Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

 
 
Session Overview
Session
Session 4-D: Medicine and biology applications 1
Time:
Wednesday, 11/Oct/2023:
9:30am - 10:45am

Session Chair: Peter Ambjörn Fritzson
Location: Charles

Session Topics:
Medicine and biology applications

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Presentations

Creating cardiovascular and respiratory models using Physiolibrary 3.0

Marek Mateják1,2

1Charles University inPrague, Czech Republic; 2Institute for Clinical and Experimental Medicine, Czech Republic

The free open-source library called Physiolibrary (https://github.com/MarekMatejak/Physiolibrary) in version 3.0 recast components from physiological domains such as hydraulic (cardiovascular), thermal, osmotic and chemical into Modelica Standard Library (MSL) concept of Fluid/Media. Components are expanded to include gases transports, acid-base, electrolytes, nutrients delivery and endocrines by simple selecting pre-packaged media. They can be connected directly (the same medium) or across membranes (different media), allowing small physiological models to be easily coupled within more quantitative ones with minimal effort.

Mateják-Creating cardiovascular and respiratory models using Physiolibrary 30-189_a.pdf


Design ideas behind Bioprocess Library for Modelica

Jan Peter Axelsson

Vascaia AB, Sweden

In this paper I describe key design ideas behind the Bioprocess Library. The library facilitates modelling and simulation of bioprocesses mainly for the pharmaceutical industry. It borrows some structures from MSL Fluid and Media but differs in central design choices and is much simpler. A typical application consists of both configuration of standard components from the library and tailor-made Modelica code defining the application dependent medium and bioprocess reactions. The guiding idea is that configuration of components works well for defining the setup of process equipment for a production line, while more flexibility is needed for modelling bioprocess reactions and therefore equations are used. Another central design idea is that components of equipment are centrally adapted to the medium used. One could say that the library is parameterised with the application media and reaction models. The focus of this paper is structural aspects of the library rather than the content.

Axelsson-Design ideas behind Bioprocess Library for Modelica-169_a.pdf


Bodylight.js 2.0 - Web components for FMU simulation, visualisation and animation in standard web browser

Tomas Kulhanek1,2, Arnost Mladek2, Jiri Kofranek1,2, Filip Jezek2,3

1Creative Connections, Czechia; 2Charles University, Prague, Czechia; 3University of Michigan, Ann Arbor, USA

Simulators used in teaching and education comprises a

mathematical model of the system under study and user

interface that allows to control model inputs and visual-

ize model state and results in an intuitive way. This pa-

per presents web components - that can be used to build

in-browser web simulator. The models used for the web

simulators must be written in standard Modelica language

and compiled as standard FMU (Functional mockup unit).

The toolchain version Bodylight.js 2.0 contains tools to

compile FMU into WebAssembly language able to be exe-

cuted directly by web browser. Bodylight.js 2.0 web com-

ponents can be then used to combine model, interactive

animation and charts into rich web document in HTML or

Markdown syntax only without any other programming or

scripting.

Kulhanek-Bodylightjs 20 - Web components for FMU simulation, visualisation and animation-137_a.pdf


 
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