Conference Agenda

8:30am - 8:42am
ID: 179 / 4.1: 1

MACHINE-LEARNING-SUPPORTED PERSONALISATION OF ZERO-DIMENSIONAL CARDIOVASCULAR MODEL WITH BAROREFLEX

K. Tlałka^1,2, I. Halliday^2,3, A. Narracott^2,3, M. Malawski^1,4

1: Sano Centre for Computational Medicine, Poland; 2: University of Sheffield, United Kingdom; 3: Insigneo Institute, United Kingdom; 4: AGH University of Kraków, Poland

8:42am - 8:54am
ID: 192 / 4.1: 2

PARAMETER ESTIMATION OF A LUMPED-PARAMETER CARDIOVASCULAR MODEL, WITH A NOVEL UNSCENTED KALMAN FILTER

A. L. Thornton¹, I. Halliday¹, R. H Clayton¹, H. Saxton², X. Xu¹

1: University of Sheffield, United Kingdom; 2: Astellas Pharma

8:54am - 9:06am
ID: 329 / 4.1: 3

AN INTEGRATED 1D 0D MODEL OF THE CARDIORESPIRATORY SYSTEM WITH SHORT TERM CARDIOPULMONARY CONTROL MECHANISMS

C. Dalmaso¹, P. J. Blanco², L. O. Müller¹

1: Department of Mathematics, University of Trento, Italy; 2: National Laboratory for Scientific Computing, LNCC/MCTI, Brazil

9:06am - 9:18am
ID: 368 / 4.1: 4

PARAMETER IDENTIFICATION IN AN ECMO PHANTOM CIRCULATION MODEL

A. Utrera^1,2, C. Bertoglio¹, W. Huberts³, M. Rutten³

1: University of Groningen, The Netherlands; 2: University of Santiago, Chile; 3: Eindhoven University of Technology, The Netherlands

9:18am - 9:30am
ID: 427 / 4.1: 5

MODELING VENOUS HEMODYNAMICS: A 1D FRAMEWORK FOR INVESTIGATING VALVES AND EXTERNAL COMPRESSION

S. Ferlito¹, M. Reda¹, A. Sen², J. Alastruey², S. Avril¹

1: Ecole des Mines de Saint-Etienne, Saint-Etienne, France, Italy; 2: King's College London, London, United Kingdom

9:30am - 9:42am
ID: 630 / 4.1: 6

A 0D MODEL REPRESENTING HUMAN RESPONSE TO HYPERGRAVITY

K. Czechowicz^1,2, A. Narracott^1,2, R. D. Hose^1,2, R. Anderton³, I. Halliday^1,2, P. D Morris^1,2,4

1: The University of Sheffield, United Kingdom; 2: Insigneo Institute, United Kingdom; 3: UK Civil Aviation Authority, United Kingdom; 4: Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom

9:42am - 9:54am
ID: 241 / 4.1: 7

ESTIMATION OF ARTERIAL WALL MATERIAL PARAMETERS FROM NON-INVASIVELY MEASURABLE BLOOD PRESSURE SIGNALS

K. Pálfalvi, R. Wéber

Budapest University of Technology and Economics, Hungary

9:54am - 9:57am
ID: 199 / 4.1: 8

SECONDARY FLOWS INSIDE ARTIFICAL VESSEL GEOMETRIES

P. Friedrich, B. Csippa, G. Paál

Budapest University of Technology and Economics, Hungary

9:57am - 10:00am
ID: 243 / 4.1: 9

MULTISCALE HEMODYNAMIC MODELING OF ECMO-INDUCED ALTERATIONS IN MICROVASCULAR FILTRATION AND THROMBOTIC RISK

R. Wéber¹, M. Judit¹, F. Romano²

1: Department of Hydrodynamic Systems, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, 1111, Hungary; 2: Univ. Lille, CNRS, ONERA, Arts et Métiers Institute of Technology, Centrale Lille, UMR 9014 - LMFL - Laboratoire de Mécanique des Fluides de Lille - Kampé de Fériet, F-59000 Lille, France

10:00am - 10:03am
ID: 299 / 4.1: 10

TURBULENCE-INDUCED HEMOLYSIS IN A TAYLOR-COUETTE-DEVICE: DESIGN AND EXPERIMENTAL CHARACTERIZATION

M. Wiegand^1,2, A. Groh³, S. Bender^1,2, K. Pölkow³, C. N. Nayeri³, K. Vellguth^1,2, V. Froese^1,2, J. Brüning^1,2, S. Martinke³, O. Paschereit³, L. Goubergrits^1,2

1: Deutsches Herzzentrum der Charité, Institute of Computer-assisted Cardiovascular Medicine (ICM), Germany; 2: Charité—Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Germany; 3: Hermann-Föttinger Institute, Technische Universität Berlin, Gemany

10:03am - 10:06am
ID: 490 / 4.1: 11

ELECTROMECHANICAL SIMULATION OF LEFT VENTRICULAR CONTRACTION AFTER MYOCARDIAL INFARCTION

A. Schlief¹, L. Obermeier¹, L. Verbeek², C. Knosalla³, N. Solowjowa³, L. Goubergrits¹

1: Deutsches Herzzentrum der Charité, Institute of Computer-assisted Cardiovascular Medicine (ICM), Berlin, Germany; 2: Eindhoven University of Technology, Eindhoven, The Netherlands; 3: Deutsches Herzzentrum der Charité, Department of Cardiothoracic and Vascular Surgery, Berlin, Germany

10:06am - 10:09am
ID: 578 / 4.1: 12

THE ROLE OF LAYER-SPECIFIC COMPOSITION AND FIBER ORIENTATION ON THE MECHANICAL RESPONSE OF PORCINE PULMONARY ARTERIES

J. A Peña¹, M. A Martinez^1,2, E. Peña^1,2

1: Universidad de Zaragoza, Spain; 2: CIBER-BBN, Centro de Investigación en Red en Bioingeniería, Spain

10:09am - 10:12am
ID: 577 / 4.1: 13

LATENT DYNAMICS NEURAL NETWORK MODELS OF CARDIAC ELECTROPHYSIOLOGY IN A PATIENT-SPECIFIC LEFT ATRIUM

M. Di Ridolfi^1,4, S. Pagani², F. Caforio^1,3,4, F. Regazzoni², L. Dede'², L. Preziosi⁵

1: Dept. of Mathematics and Scientific Computing, NAWI Graz, University of Graz, Austria; 2: MOX, Dept. of Mathematics, Politecnico di Milano, Italy; 3: Gottfried Schatz Research Center, Medical University of Graz, Austria; 4: BioTechMed-Graz, Austria; 5: Dept. of Mathematical Sciences, Politecnico di Torino, Italy

10:12am - 10:15am
ID: 613 / 4.1: 14

HIGH SPEED ACUTE CARDIAC INFARCTION SIMULATIONS USING THE NEURAL NETWORK FINITE ELEMENT METHOD

B. Thomas, M. Sacks

University of Texas at Austin, United States of America

10:15am - 10:18am
ID: 229 / 4.1: 15

PATIENT-SPECIFIC 1D–3D SIMULATIONS OF BLOOD AND CONTRAST FLOW IN STENTED VENOUS SEGMENTS

M. Baragona¹, W. Mhaouch², P. Haulez², A. van der Horst¹, S. Shulepov¹, J.-M. Armengol Collado¹, B. Frackowiak¹

1: Royal Philips, Netherlands, The; 2: Eindhoven University of Technology, The Netherlands

8:30am - 8:42am
ID: 181 / 4.2: 1

COUPLING BAYESIAN INFERENCE AND SENSITIVITY ANALYSIS FOR IN-SILICO THERAPY GUIDANCE OF HYPOTENSION DURING SURGERY

J.-N. Thiel¹, M. Zlicar², U. Steinseifer¹, B. Kirn³, M. Neidlin¹

1: Cardiovascular Engineering, Applied Medical Engineering, Medical Faculty, RWTH Aachen University, Aachen, Germany; 2: Clinical Department of Anaesthesiology and Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia; 3: Institute of Physiology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia

8:42am - 8:54am
ID: 293 / 4.2: 2

REDUCED ORDER MODELS FOR REAL-TIME PATIENT-SPECIFIC CARDIOVASCULAR SIMULATIONS VIA WEB-SERVER

G. Rozza

SISSA, Italy

8:54am - 9:06am
ID: 318 / 4.2: 3

EVALUATION OF A DIGITAL TWIN FOR REAL-TIME CARDIAC CONTRACTILITY ESTIMATION USING SYNTHETIC AND IN VIVO DATA

S. Snijders^1,2, M. Rutten¹, J. Sels^3,4, P. Tonino^1,5, W. Huberts^1,6

1: Eindhoven University of Technology, The Netherlands; 2: Laurentius Hospital, The Netherlands; 3: Maastricht UMC+, The Netherlands; 4: CARIM Cardiovascular Research Institute Maastricht, The Netherlands; 5: Catharina Hospital, The Netherlands; 6: University of Amsterdam, The Netherlands

9:06am - 9:18am
ID: 336 / 4.2: 4

INVESTIGATING THE TRANSLATION GAP TO UNLOCK THE POTENTIAL OF DIGITAL TWINS IN HEALTHCARE

S. Bridio¹, G. Luraghi², J. F. Rodriguez Matas², G. Dubini², F. Migliavacca^2,3, M. Whelan¹

1: European Commission - Joint Research Centre (JRC), Ispra, Italy; 2: Department of Chemistry, Materials and Chemical Engineering “Giulio Natta”, Politecnico di Milano, Italy; 3: Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy

9:18am - 9:30am
ID: 340 / 4.2: 5

AN INTEGRATED DECISION SUPPORT SYSTEM FOR HYPERTROPHIC CARDIOMYOPATHY DISEASE MANAGEMENT

N. Faiem, A. Kallonen, M. van Gils

Tampere University, Finland

9:30am - 9:42am
ID: 561 / 4.2: 6

DIGITAL TWIN INTEGRATING MULTISCALE DATA AND MODELS FOR STRATIFICATION OF HYPERTROPIC CARDIOMYOPATHY

J. Hyttinen¹, K. Aalto-Setälä¹, A. Afantitis¹¹, F. Agakov², A. Oravio Bueno³, T. Crist⁵, K. Curran⁴, V. Le Rolle⁶, L. Mainardi⁷, S. Severi⁹, i. Olivetto⁸, M. van Gils¹, M. von Tottleben¹⁰

1: Tampere University, Finland; 2: Pharmatics Ltd; 3: University of Oxford; 4: University College Dublin; 5: University Klinikum Eppendorf; 6: University of Rennes; 7: Politecnico di Milan; 8: University of Florence; 9: University of Bologna; 10: Empirica Ltd; 11: NovoMechnaics Ltd

9:42am - 9:54am
ID: 624 / 4.2: 7

CAN MAKING CARDIOVASCULAR SYSTEM MODELS EASY TO CALIBRATE BRIDGE THE GAP TO THE INTENSIVE CARE UNIT?

F. Argus¹, B. Ghitti¹, M. Shafieizadegan¹, A. Sharifzadeh-Kermani¹, M. Gee², S. Creamer¹, B. Ebrahimi¹, E. Guy⁴, J. Fisher³, J. G. Chase⁴, M. Tawhai¹, G. Maso Talou¹

1: Auckland Bioengineering Institute, University of Auckland, NZL; 2: University of Delaware, USA; 3: FMHS, University of Auckland, NZL; 4: Department of Mechanical Engineering, University of Canterbury, NZL

9:54am - 10:06am
ID: 372 / 4.2: 8

TOWARDS REAL-TIME TAVR DIGITAL TWINS: 2D NAVIER-STOKES PINN IN STENOTIC FLOWS AND CORONARY ASSESSMENT

J. Gosselin¹, R. Leask¹, R. Cecere¹, F. Couët², S. Lalancette², R. Mongrain¹

1: McGill University, Canada; 2: Haemonectics Quebec, Canada

10:06am - 10:09am
ID: 556 / 4.2: 9

AN OPTIMIZATION FRAMEWORK FOR DESIGNING MECHANICALLY INFORMATIVE SOFT TISSUE EXPERIMENTS

U. Manack^1,2, B. Alheit¹, N. Famaey², M. Peirlinck¹

1: Delft University of Technology; 2: KU Leuven

10:09am - 10:12am
ID: 277 / 4.2: 10

SINO-ATRIAL NODE MODEL FOR INFERRING AUTONOMIC ACTIVITY FROM HEART RATE VARIABILITY

C. Dong, G. Talou, K. Tran, F. Argus

University of Auckland, New Zealand

10:12am - 10:15am
ID: 430 / 4.2: 11

A COMPARATIVE INVESTIGATION ON DIFFERENT SOLUTIONS OF 1D MODEL OF BLOOD FLOW

E. Vaezi¹, J. Hernández², E. Soudah^1,2

1: International Center for Numerical Methods in Engineering(CIMNE), Barcelona, Spain; 2: Universitat Politècnica de Catalunya (UPC), Barcelona, Spain

10:15am - 10:18am
ID: 439 / 4.2: 12

PREDICTING POST-TEER HEMODYNAMICS IN MITRAL REGURGITATION USING PATIENT-SPECIFIC MODELLING

J. Franz^1,2, F. Barbieri^2,3, V. Exarchos^2,3, K. Vellguth^1,2, J. Brüning^1,2, A. Borzistaia^1,2, M. Reinthaler^2,3, T. Kühne^1,2, L. Goubergrits^1,2

1: Deutsches Herzzentrum der Charité, Institute of Computer-assisted Cardiovascular Medicine, Berlin, Germany; 2: Charité - Universitätsmedizin Berlin, Berlin, Germany; 3: Deutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, Germany

10:18am - 10:21am
ID: 472 / 4.2: 13

INFLUENCE OF AORTIC ARCH MORPHOLOGY ON CARDIOGENIC EMBOLIC STROKE RISK: A CFD-BASED FRAMEWORK

C. Bettinelli¹, I. Ianniruberto¹, F. Morelli^1,2, Y. Tatari³, A. Arzani³, D. Mazzaccaro^2,4, E. Votta¹, F. Sturla^2,1

1: Politecnico di Milano, Milano, Italy; 2: IRCCS Policlinico San Donato, San Donato Milanese, Italy; 3: University of Utah, Salt Lake City, USA; 4: Università degli Studi di Milano, Milano, Italy

10:21am - 10:24am
ID: 524 / 4.2: 14

SEMI-AUTOMATED GENERATION OF SURGICAL BAFFLE GEOMETRY FOR BIVENTRICULAR REPAIR

E. S. Martinez, A. D. Kaiser, A. K. Reed, S. W. Stocker, A. Sharir, P. S. Choi, S. A. Maskatia, M. R. Ma, A. L. Marsden

Stanford University, United States of America

10:24am - 10:27am
ID: 551 / 4.2: 15

MACHINE LEARNING SURROGATE MODEL FOR HIPSC CARDIOMYOCYTE ELECTROMECHANICS

O. Ylinen, O. Noita, A. Ahola, J. Koivumäki, J. Hyttinen

Tampere University, Finland

10:27am - 10:30am
ID: 560 / 4.2: 16

AI-DRIVEN HEART FAILURE RISK PREDICTION FROM ECG VERSUS TRADITIONAL CLINICAL RISK MEASURES: WHICH PERFORMS BETTER?

X. An^1,2, W. Sun⁵, S. V Kalmady⁵, J. A White⁶, A. J Swift^1,2,3,4, R. Greiner^5,7, P. Kaul⁵, C. Chen^1,2

1: University of Sheffield, United Kingdom; 2: Insigneo Institute, United Kingdom; 3: Sheffield Teaching Hospitals, United Kingdom; 4: National Institute for Health and Care Research, United Kingdom; 5: University of Alberta, Canada; 6: University of Calgary, Canada; 7: Alberta Machine Intelligence Institute, Canada

8:30am - 8:42am
ID: 143 / 4.3: 1

A METHODOLOGY FOR DESIGNING OPTIMIZED PATIENT-SPECIFIC BONE SCAFFOLD FROM ROUTINE CLINICAL IMAGES

N. Olivera¹, L. D'Andrea¹, E. Zamengo², P. Vena¹

1: Politecnico di Milano, Italy; 2: Ludwig Boltzmann Institute of Osteology and AUVA, Austria

8:42am - 8:54am
ID: 160 / 4.3: 2

GENERATING AN ATLAS OF PAEDIATRIC SKELETAL MODELS FOR MORPHOLOGICAL ASSESSMENT

H. Talbott^1,2, G. Allison^1,2, A. Moayedi^1,2, M. Cohen^1,2,3, E. Dall'Ara^1,2, A. Offiah^1,2,4, X. Li^1,2

1: University of Sheffield, United Kingdom; 2: Insigneo Institute, United Kingdom; 3: Sheffield Teaching Hospitals NHS Foundation Trust, United Kingdom; 4: Sheffield Children’s Hospital, United Kingdom

8:54am - 9:06am
ID: 189 / 4.3: 3

CHARACTERIZING HEALTHY HIP DEVELOPMENT IN KIDS USING A STATISTICAL SHAPE AND APPEARANCE MODEL

S. Attar¹, H. Isaksson¹, M. K Karlsson², C. J. Tiderius², L. Grassi¹

1: Department of Biomedical Engineering, Lund University, Lund, Sweden; 2: Division of Orthopaedics, Department of Clinical Sciences, Lund University, Lund, Sweden

9:06am - 9:18am
ID: 235 / 4.3: 4

UNCERTAINTY EVALUATION OF AN ARTIFICIAL INTELLIGENCE MODEL FOR LEG-LENGTH ESTIMATION IN A CLINICAL SETTING.

M. Ronat^1,2, S. Beddiaf², R. Philippot^3,1, L. Cheze⁴

1: LIBM - Inter-university Laboratory of Human Movement Science, University Lyon - University Jean-Monnet Saint-Etienne, France; 2: ISTP - Higher Institute of Advanced Performance Techniques, Saint-Etienne, France; 3: CUSA - Department of Orthopaedic Surgery, University Hospital Centre of Saint-Étienne, Saint-Etienne EA 7424, France; 4: LBMC - Univ Lyon, Univ Gustave Eiffel, Univ Claude Bernard Lyon 1, UMR_T 9406, F-69622 Lyon, France

9:18am - 9:30am
ID: 249 / 4.3: 5

STATISTICAL SHAPE MODELING TO ASSESS THE MORPHOLOGICAL VARIABILITY OF TIBIAL MEDULLARY CANAL

F. Montigiani, G. Galteri, L. Cristofolini

Dept. of Industrial Engineering, University of Bologna - Alma Mater Studiorum, Italy

9:30am - 9:42am
ID: 287 / 4.3: 6

PHYSICS-INFORMED MACHINE LEARNING FOR ESTIMATING CONSTITUENT-SPECIFIC PROPERTIES OF CARTILAGE

P. Tanska^1,2, A. Salo¹, M. E. Mononen¹

1: University of Eastern Finland, Finland; 2: Kuopio University Hospital, Wellbeing Services County of North Savo, Finland

9:42am - 9:54am
ID: 306 / 4.3: 7

UISS-BMR: A MECHANISTIC AGENT-BASED MODEL OF IMMUNE– BONE CROSSTALK DURING FRACTURE HEALING

F. Cernuto, V. Russo

University of Catania, Italy

9:54am - 10:06am
ID: 421 / 4.3: 8

THE MECHANICAL INTERPLAY BETWEEN BONE AND SCAFFOLD - A COMPUTATIONAL ANALYSIS

H. Souhail¹, L. D'Andrea², E. Zamengo³, S. Blouin³, A. Berzlanovich⁴, M. A. Hartmann³, P. Vena², D. Ruffoni¹

1: University of Liège, Liège, Belgium; 2: Politecnico di Milano, Milan, Italy; 3: Ludwig Boltzmann Institute of Osteology, Vienna, Austria; 4: Center of Forensics Medicine, Vienna, Austria

10:06am - 10:18am
ID: 508 / 4.3: 9

DESIGN, MANUFACTURING, AND TESTING OF A SYSTEM FOR IN VITRO SKELETAL MUSCLE TISSUE MECHANICAL STIMULATION.

N. Klein Hofmeijer¹, C. Rivares Benitez¹, J. Rouwkema², M. Sartori¹

1: Neuromuscular robotics University of Twente, The Netherlands; 2: Engineering Organ Support Technologies University of Twente, The Netherlands

10:18am - 10:30am
ID: 601 / 4.3: 10

SOFT TISSUE DRIVEN BONE REMODELLING – A FRAMEWORK FOR PATIENT-SPECIFIC DENTAL PROTHESIS DESIGN

J. Chen¹, J. Zhong², M. Swain³, Q. Li³, L. Wang¹

1: University of Exeter, United Kingdom; 2: Max Planck Institutes of Colloids and Interfaces; 3: The University of Sydney

8:30am - 8:42am
ID: 122 / 4.4: 1

DECOUPLING INTER- FROM INTRA-CELLULAR STRESSES

R. Aparicio Yuste^1,2, L. Hundsdorfer¹, E. Bastounis¹, M. J. Gomez-Benito³

1: Interfaculty Institute of Microbiology and Infection Medicine, Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI, EXC 2124), University of Tübingen, Germany; 2: Friedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany; 3: Engineering Research Institute of Aragon (I3A), University of Zaragoza, Spain.

8:42am - 8:54am
ID: 135 / 4.4: 2

TOWARDS AN IN SILICO MODEL OF THE GUT-BRAIN AXIS: FROM GASTROINTESTINAL STIMULATION TO COGNITIVE PERCEPTION

E. L. Carniel¹, I. Toniolo¹, A. Berardo¹, C. G. Fontanella¹, B. Pomaro¹, G. Mazzucco¹, L. Polese¹, S. Perretta²

1: Centre for Mechanics of Biological Materials, University of Padova, Italy; 2: Department of General Surgery, CHRU Strasbourg, IHU Strasbourg, France

8:54am - 9:06am
ID: 557 / 4.4: 3

THE ECOSYSTEM WITHIN US: SIMULATING MICROBIOME DYNAMICS TOWARDS A DIGITAL TWIN OF THE HUMAN GUT

S. Qathan¹, D. Popp², F. Centler¹

1: University of Siegen, Germany; 2: University of Leipzig Medical Center, Germany

9:06am - 9:18am
ID: 419 / 4.4: 4

[LIB]OPENCOR: MOVING COMPUTATIONAL BIOLOGY TO THE WEB

A. Garny, D. P Nickerson, P. J Hunter

University of Auckland, New Zealand

9:18am - 9:30am
ID: 171 / 4.4: 5

FROM NEURAL DYNAMICS TO PRECISION THERAPY FOR PARKINSON’S DISEASE: A MULTISCALE IN SILICO MODEL OF CORTICAL EXCITABILITY AND NETWORK IMBALANCE,

J. Jung^1,3, H.-Y. Chu^2,3, W. Lytton^1,3

1: Department of Physiology and Pharmacology, SUNY Downstate Health Sciences University, Brooklyn, NY., USA; 2: Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington DC., USA; 3: Aligning Science Across Parkinson’s (ASAP) Collaborative Research Network, Chevy Chase, Maryland, USA

9:30am - 9:42am
ID: 404 / 4.4: 6

A SYSTEMS APPROACH TO REELIN-NOTCH SIGNALING TO DECIPHER REGULATORY DYNAMICS IN LYMPHANGIOGENESIS

S. Bekisz¹, Y. Graine¹, A. Noël², L. Geris^1,3, L. Ladeira¹

1: Biomechanics Research Unit, University of Liège, Belgium; 2: Laboratory of Biology of Tumor and Development, University of Liège, Belgium; 3: Skeletal Biology and Engineering Research Center, KU Leuven, Belgium

9:42am - 9:54am
ID: 322 / 4.4: 7

A PBK-TD GUT MICROBIOME MODEL OF THE FIRST 1000 DAYS OF LIFE: TOWARDS A PREVENTIVE HEALTHCARE DIGITAL TWIN

T.-K. LY, A. G. HOEKSTRA, V. M. SHERATON

Computational Science Lab, Informatics Institute, Faculty of Science, University of Amsterdam, The Netherlands

9:54am - 10:06am
ID: 302 / 4.4: 8

PERSONALIZED MODELS TO UNVEIL MECHANISMS OF ENGINEERED T-CELL THERAPY IN MULTIPLE MYELOMA

S. Orozco-Ruiz^1,2,3, V. Noël^1,2,3, G. Stoll^1,2,3, S. Pankaew^1,2,3, L. Gasull-Celades⁴, E. van Vliet⁴, P. Hernández-López⁴, P. Brazda⁴, F. Keramati⁴, C. Kuhn⁵, M. Rade⁵, D. Fandrei^5,7,9, M. Alb⁶, Z. Sebestyén^4,10, M. Merz^5,7,8,9, J. Kuball^4,10, K. Reiche^5,11,9,12, E. Barillot^1,2,3, L. Calzone^1,2,3

1: Institut Curie, Université PSL, F-75005, Paris, France; 2: INSERM, U1331, F-75005, Paris, France; 3: Mines ParisTech, Université PSL, F-75005, Paris, France; 4: Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; 5: Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany; 6: Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital Würzburg; 7: Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital of Leipzig; 8: Myeloma and Cellular Therapy Services, Memorial Sloan Kettering Cancer Center, New York, NY, USA; 9: Cancer Center Central Germany (CCCG) Leipzig-Jena, University Hospital of Leipzig, Leipzig, Germany; 10: Department of Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; 11: Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany; 12: Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), Dresden, Leipzig, Germany

10:06am - 10:09am
ID: 137 / 4.4: 9

TOWARDS A DIGITAL TWIN OF THE HUMAN GUT: A MULTISCALE COUPLED PDE MODEL OF HOST-MICROBIOTA INTERACTION

E. Pastremoli, B. Laroche, L. Sala

INRAE, France

10:09am - 10:12am
ID: 356 / 4.4: 10

REAL-TIME PREDICTION OF EARLY LIVER ALLOGRAFT DYSFUNCTION USING AN IMAGE-BASED MULTISCALE BIOMECHANICAL MODEL

L. Mandl^1,2, S. Gerhäusser¹, A. Schnurpel², A.-L. Hoh², U. Dahmen³, M. König⁴, T. Ricken¹, H.-M. Tautenhahn²

1: University of Stuttgart, Germany; 2: University of Leipzig Medical Center, Germany; 3: Jena University Hospital, Germany; 4: Humboldt University of Berlin, Germany

10:12am - 10:15am
ID: 555 / 4.4: 11

SMOOTH MUSCLE CELL POPULATION VARIATION

N. Anderton¹, O. Noita¹, F. Menna², J. Suihkonen¹, A. Ben-Tolila², J. Koivumäki¹, J. Duprez², V. Le Rolle², J. Hyttinen¹

1: Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; 2: University of Rennes, CHU Rennes, Inserm, LTSI-UMR, Rennes, France

10:15am - 10:18am
ID: 594 / 4.4: 12

A REPRODUCIBLE FRAMEWORK FOR COUPLING TISSUE-LEVEL AND INTRACELLULAR KINETIC MODELS OF HEPATOCYTES

M. Pedrazzi¹, P. Kottman¹, M. Cascante de Serratosa², D. Drasdo¹

1: Inria Saclay, France; 2: Barcelona University, Spain

10:18am - 10:21am
ID: 638 / 4.4: 13

BONE REMODELING MULTISCALE COMPUTACIONAL MODEL: COUPLING CELLULAR AND TISSUE DYNAMICS

A. Verly, P. Amaral, F. Bastos, L. Assis, B. Quintela

Federal University of Juiz de fora, Brazil

10:21am - 10:24am
ID: 661 / 4.4: 14

IN SILICO DESIGN OF MG-BASED DEGRADABLE POROUS SCAFFOLDS FOR THE REPAIR OF CRITICAL-SIZE DEFECTS

S. Nguyen¹, M. Barzegari², L. Geris^1,3

1: KU Leuven, Belgium; 2: TU Eindhoven, The Netherlands; 3: University of Liège, Belgium

10:24am - 10:27am
ID: 668 / 4.4: 15

MECHANICS OF DIFFUSIVE CROSSLINKERS IN BIOPOLYMER NETWORKS: A CONTINUUM APPROACH

L. Pacheco^1,2, M. Parente^1,2, J. Ferreira¹

1: Faculty of Engineering - University of Porto, Portugal; 2: INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering, Portugal

10:27am - 10:30am
ID: 297 / 4.4: 16

PRECLINICAL TOOL TO ESTIMATE OSTEOPOROTIC WOVEN BONE MECHANICS BASED ON EXPERIMENTAL DATA

J. J. Toscano-Angulo¹, J. Mora-Macías², P. Blázquez-Carmona³, E. Reina-Romo¹

1: University of Seville, Spain; 2: University of Huelva, Spain; 3: University of Cadiz, Spain

8:30am - 8:42am
ID: 324 / 4.5: 1

ESTIMATION OF ACTIVE MYOCARDIAL CONTRACTILITY VIA PHYSICS-INFORMED NEURAL NETWORKS FOR SCAR DETECTION

M. Höfler^1,4, F. Regazzoni², S. Pagani², E. Karabelas^1,4, C. Augustin^3,4, G. Haase^1,4, G. Plank^3,4, F. Caforio^1,3,4

1: Dept. of Mathematics and Scientific Computing, NAWI Graz, University of Graz, Austria; 2: MOX, Dept. of Mathematics, Politecnico di Milano, Italy; 3: Gottfried Schatz Research Center, Medical University of Graz, Austria; 4: BioTechMed-Graz, Austria

8:42am - 8:54am
ID: 154 / 4.5: 2

PERSONALIZED TRACKING OF CORE TEMPERATURE FROM WEARABLES VIA A PHYSICS-GUIDED BAYESIAN ODE

Y. Cao, Y. Cao

Nanyang Technological University, Singapore

8:54am - 9:06am
ID: 550 / 4.5: 3

PRE-OPERATIVE, DIAGNOSIS-ADJUSTED RISK PREDICTION OF PROLONGED HOSPITALISATION AFTER PAEDIATRIC CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS

F. E. G. Kessler¹, A. Zenonos^1,2, R. Issitt^1,2, V. Muthurangu¹

1: University College London, United Kingdom; 2: Great Ormond Street Hospital for Children

9:06am - 9:18am
ID: 234 / 4.5: 4

UNSUPERVISED MATERIAL MODEL DISCOVERY OF MYOCARDIAL TISSUE BEHAVIOR

M. Peirlinck

Delft University of Technology, The Netherlands

9:18am - 9:30am
ID: 141 / 4.5: 5

SCALABLE INFERENCE OF GUT MICROBIOTA LOTKA–VOLTERRA MODELS WITH PHYSICS-INFORMED NEURAL NETWORKS

L. Sala

Univ. Paris-Saclay, INRAE, MaIAGE; Inria, MUSCA, France

9:30am - 9:42am
ID: 321 / 4.5: 6

A FEASIBILITY PIPELINE: STRUCTURING MULTIMODAL REAL-WORLD DATA FOR DIGITAL TWIN DEVELOPMENT

A. SANDRALEGAR^1,2, E. Golubeva³, L. Bührer^3,4, S. Morel⁵, P. Bijlenga^1,2

1: Division of Neurosurgery, Geneva University Hospitals, Switzerland; 2: Faculty of Medicine, University of Geneva, Switzerland; 3: Centre for Computational Health, Institute of Computational Life Sciences, Zurich University of Applied Sciences, Switzerland; 4: Department of Mathematical Modeling and Machine Learning, University of Zurich, Switzerland; 5: NeuroCentre, Geneva University Hospitals, Switzerland

9:42am - 9:54am
ID: 115 / 4.5: 7

ADAPTIVE MODEL REDUCTION FOR EFFICIENT DATA AUGMENTATION FOR MACHINE LEARNING CLASSIFICATION

M. Stefanati¹, S. Gahima², J. F. Rodríguez Matas¹, A. García‑González^2,3, P. Díez^2,3

1: DCMC, Politecnico di Milano, Italy; 2: Universitat Politècnica de Catalunya, Spain; 3: CIMNE, Spain

9:54am - 10:06am
ID: 174 / 4.5: 8

ROBUST LEARNING DOMAIN FORMULATION FOR DEEP LEARNING MODELS IN A SMALL DATA REGIME

K. Zhao¹, B. Ghitti¹, M. Nash^1,2, G. Maso Talou¹

1: Auckland Bioengineering Institute, University of Auckland, New Zealand; 2: Department of Engineering Science and Biomedical Engineering, University of Auckland, New Zealand

10:06am - 10:09am
ID: 124 / 4.5: 9

PATIENT-SPECIFIC 0D CIRCULATION MODELING WITH REGRESSION-BASED PARAMETER UPDATES TO PREDICT POST-HEPATECTOMY OUTCOMES

F. Songia¹, K. Hakkakian², S. Roullet^2,3, A. Coilly^2,4, N. Golse^2,4, I. Vignon-Clementel¹

1: Inria Saclay, France; 2: AP-HP Hôpital Paul-Brousse; 3: Inserm U1176, Université Paris-Saclay; 4: Inserm U1193, Université Paris-Saclay

10:09am - 10:12am
ID: 169 / 4.5: 10

LLM + MULTISCALE MODELING FOR NEUROLOGY

W. Lytton¹, G. Cedersund², J. Lee¹, R. McDougal³, A. Newton¹, C. Kelley⁴, J. Jung¹, M. DiStasio³

1: DHSU, United States of America; 2: Linkopings University, Sweden; 3: Yale, USA; 4: McGill, Canada

10:12am - 10:15am
ID: 128 / 4.5: 11

GLUCODIFFSURV: TREATMENT-AWARE CONTINUOUS-TIME DIFFUSION FORECASTING WITH TIME-TO-HYPOGLYCEMIA RISK

S. Maqsood¹, E. Belousovienė², T. Tamosuitis², R. Maskeliūnas¹

1: Vytautas Magnus University, Lithuania; 2: University of Health Sciences, Lithuania

10:15am - 10:18am
ID: 168 / 4.5: 12

GNN-BASED SURROGATE MODEL FOR OBSTETRIC INJURY PREDICTION

R. Moura^1,2, D. Oliveira¹, D. Antunes², D. Fidalgo¹, M. Parente²

1: INEGI, Portugal; 2: Faculty of Engineering of the University of Porto, Portugal

10:18am - 10:21am
ID: 592 / 4.5: 13

IDENTIFIABILITY OF LATENT TRAJECTORIES WITH NEURAL ODES IN SMALL DATA REGIMES

T. Rachel¹, H. Yang¹, T. Litwin¹, M. Karakioulaki², M. Hess¹

1: Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany; 2: Department of Dermatology, Medical Faculty and Medical Center, University of Freiburg, Freiburg, Germany

10:21am - 10:24am
ID: 403 / 4.5: 14

HUMAN-LEVEL MRS SCORING FROM NEUROSURGICAL LETTERS USING A LARGE LANGUAGE MODEL

A. SANDRALEGAR^1,2, A. Bornet³, E. Benguettat¹, F. Ravarelli¹, P. E. Constanthin^1,2, A. Lavé¹, J. Haemmerli^1,4, I. Janssen¹, J. Issa², E. Qaderdan², E. G. Godin², K. Schaller^1,2, D. Teodoro³, P. Bijlenga^1,2

1: Geneva University Hospitals, Switzerland; 2: Faculty of Medicine, University of Geneva, Switzerland; 3: Data Science for Digital Health (DS4DH), Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Switzerland; 4: Department of Neurosurgery, Winterthur Kantonsspital, Switzerland

10:24am - 10:27am
ID: 216 / 4.5: 15

SYNTHETIC PATIENTS TO ENHANCE MULTIPLE SCLEROSIS TRIAL DESIGN VIA COVARIATE ADJUSTMENT

M. Franzese¹, R. Reggio³, E. Dolcetti², M. Aiello¹, A. Colacino¹, D. Centonze², R. Gomeni⁴, E. Merlo Pich³, M. Salvatore¹

1: IRCSS Synlab SDN, Napoli, Italy; 2: IRCSS Neuromed, Pozzilli, Italy; 3: Gelf Health, Milano, Italy; 4: Pharmacometrica, France

8:30am - 8:42am
ID: 290 / 4.6: 1

FEMUR FRACTURE PREDICTION IN POSTMENOPAUSAL WOMEN: MULTI-COHORT CLINICAL VALIDATION OF BBCT-HIP PIPELINE

J. A. Szyszko¹, A. La Mattina², M. Amabile², C. Ripamonti³, L. Lisi³, P. Bhattacharya⁴, F. Baruffaldi², A. Aldieri¹, M. Viceconti¹

1: Department of Industrial Engineering, University of Bologna; 2: Medical Technology Laboratory, IRCCS Istituto Ortopedico Rizzoli, Bologna; 3: SSD Medicina e Reumatologia, IRCCS Istituto Ortopedico Rizzoli, Bologna; 4: Mechanical, Aerospace and Civil Engineering & INSIGNEO Institute for In Silico Medicine, University of Sheffield

8:42am - 8:54am
ID: 132 / 4.6: 2

PHANTOMLESS CALIBRATION FOR THE ESTIMATION OF BONE STRENGTH IN PAEDIATRIC FEMORA

G. Allison^1,2, S. Almutairi³, A. C Offiah^2,3, X. Li^1,2

1: School of Mechanical, Aerospace & Civil Engineering, University of Sheffield, United Kingdom; 2: Insigneo Institute, University of Sheffield, United Kingdom; 3: School of Medicine and Population Health, University of Sheffield, United Kingdom

8:54am - 9:06am
ID: 261 / 4.6: 3

FROM ASTM F543 PHYSICAL TESTING TO IN SILICO EVIDENCE: CREDIBILITY ASSESSMENT OF A DEVICE-AGNOSTIC FE MODEL

D. Benoit¹, F. Le Navéaux¹, L. Degueldre¹, M.-H. Beauséjour², Y. Petit², É. Wagnac², J. Clin¹

1: Numalogics; 2: École de Technologie Supérieure

9:06am - 9:18am
ID: 156 / 4.6: 4

TOWARDS THE VIRTUAL MOUSE TWIN FOR PRE-CLICNICAL TESTING OF NEW TREATMENTS FOR OSTEOPOROSIS

E. Dall'Ara¹, T. Valerio¹, S. Singh¹, S. Dirstaru¹, S. Farage-O'Reilly¹, V. S. Cheong¹, P. Pivonka²

1: The University of Sheffield, United Kingdom; 2: Queensland University of Technology, Australia

9:18am - 9:30am
ID: 335 / 4.6: 5

A DYNAMIC MUSCULAR-ARTICULAR DATASET FOR LOWER LIMB DIGITAL TWINS: FIRST APPLICATION AND IN VIVO VALIDATION

M. Conconi¹, M. Romeo¹, N. Sancisi¹, R. Dumas²

1: Department of Industrial Engineering, University of Bologna, Italy; 2: LBMC UMR_T 9406, University Eiffel - University Lyon 1, France

9:30am - 9:42am
ID: 363 / 4.6: 6

PHANTOM TYPE MATTERS: A BENCHTOP VALIDATION OF FEMUR STRENGTH DETERMINATION WITH FINITE ELEMENT MODELS

E. S Galliker¹, A. Dams¹, D. Jha², G. Galteri³, A. Baker¹, S. Väänänen⁴, L. Grassi⁵, V. San Cheong^2,6, H. Isaksson⁵, L. Cristofolini³, S. J Ferguson^1,2, B. Helgason^1,2

1: ETH Zürich, Switzerland; 2: Singapore-ETH Center, Singapore; 3: University of Bologna, Italy; 4: Kuopio University Hospital, Finland; 5: Lund University, Sweden; 6: University of Sheffield, United Kingdom

9:42am - 9:54am
ID: 325 / 4.6: 7

INTER-RATER VARIABILITY OF BONE FRAGMENT SEGMENTATION AND SURGICAL REDUCTION IN COMPLEX TIBIA FRACTURES

S. Comtesse^1,2, L. Sommerhalder², L. Zamboni², A. Crotta², T. Zumbrunn², B. Helgason¹, S. J. Ferguson¹

1: Institute for Biomechanics, ETH Zurich, Zurich, Switzerland; 2: CustomSurg AG, Zurich, Switzerland

9:54am - 10:06am
ID: 409 / 4.6: 8

CLINICAL METRIC ERRORS INDUCED BY THE PROPAGATION OF LANDMARKING UNCERTAINTY IN AUTOMATED TKA PLANNING

Y. Roch^1,3, D. Lozano³, N. Fougeron⁵, B. Gaulin^1,2, C. Horteur^1,2, M. Bucki¹, Y. Payan³, A. Perrier^1,3,4

1: TIMC, Univ. Grenoble Alpes, CNRS, France; 2: Grenoble-Alpes CHU, France; 3: Twinsight, France; 4: GH Diaconesses Croix St-Simon, France; 5: Univ. Rennes, Inria, CNRS, France

10:06am - 10:09am
ID: 514 / 4.6: 9

SIMULATION OF THE ABDOMINAL WALL FOR PERSONALIZED HERNIA ASSESSMENT

E. Antoniadi^1,2, M. P. Ferraz^1,3, M. Parente^1,2, E. Silva^1,2

1: Faculty of Engineering, University of Porto, Portugal; 2: LAETA/INEGI; 3: Ii3s, University of Porto, Portugal

10:09am - 10:12am
ID: 298 / 4.6: 10

GEMINI: DIGITAL TWIN FOR PERSONALIZED ISCHEMIC STROKE TREATMENT DEVICE SELECTION: A STUDY PROTOCOL

T. Brouwer^1,2, B. Emmer¹, J. Coutinho³, B. Roozenbeek⁴, S. Cornelissen⁵, H. Lingsma⁶, L. Bontempi⁷, G. Luraghi⁸, C. Majoie¹, H. Marquering²

1: Department of Radiology and Nuclear Medicine, Amsterdam UMC, The Netherlands; 2: Department of Biomedical Engineering and Physics, Amsterdam UMC, The Netherlands; 3: Department of Neurology, Amsterdam UMC, The Netherlands; 4: Department of Neurology, Erasmus MC, The Netherlands; 5: Department of Radiology and Nuclear Medicine, Erasmus MC, The Netherlands; 6: Department of Public Health, Erasmus MC, The Netherlands; 7: Department of Biomedical Engineering, Erasmus MC, The Netherlands; 8: Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials, and Chemical Engineering, Politecnico di Milano, Italy

10:12am - 10:15am
ID: 257 / 4.6: 11

CALIBRATION OF A BIOCHEMO-MECHANO MULTI-SCALE COMPUTATIONAL MODEL TO PREDICT BONE ADAPTATION

S. Dirstaru¹, S. Farage-O'Reilly¹, V. San Cheong¹, S. Singh¹, I. Bellantuono¹, P. Pivonka², E. Dall'Ara¹

1: The University of Sheffield, United Kingdom; 2: Queensland University of Technology, Australia

10:15am - 10:18am
ID: 434 / 4.6: 12

CREDIBILITY ASSESSMENT APPROACH FOR VIRTUAL IMPLANT TESTING OF CUSTOM-MADE CRANIOMAXILLOFACIAL DEVICES

S. Herrmann, T. Koett, L. Alarcon Rueda, S. Aberle, A. Beckmann

Engineering inSilico, KLS Martin SE & Co. KG, Germany

10:18am - 10:21am
ID: 258 / 4.6: 13

FROM STANDARDS TO PRACTICE: SCALABLE CREDIBILITY ASSESSMENT OF VIRTUAL PHYSIOLOGICAL HUMAN MODELS

K. Zając¹, M. Kasztelnik², P. Połeć², P. Nowakowski^1,2

1: Sano - Centre for Computational Medicine, Poland; 2: Academic Computer Centre Cyfronet AGH, Poland

10:21am - 10:24am
ID: 520 / 4.6: 14

VERIFICATION AND VALIDATION OF MDSIM’S ATLAS SPINE MODEL: APPLICATION TO A PATIENT-SPECIFIC DEFORMITY CASE

M. Tarquini, M. Rasouligandomani, S. T. Dukkipati, D. Kaçar, R. Assaker, L. Adam

MDsim, Luxembourg

10:24am - 10:27am
ID: 662 / 4.6: 15

GAIT AND MRI-DERIVED DISC MORPHOLOGY ALTERATIONS IN PATIENTS WITH LUMBAR HERNIATION

I. Mendes¹, N. Cristino^2,3, R. Fernandes^4,5,6, A. Castro^1,7

1: ESTSetúbal, Instituto Politécnico de Setúbal, Portugal; 2: Neurosurgery Department, Hospital da Luz Setúbal, Portugal; 3: iNOVA4Health, NOVA Medical School, Universidade Nova de Lisboa, Portugal; 4: ESS, Instituto Politécnico de Setúbal, Portugal; 5: Comprehensive Health Research Center, NOVA Medical School, Universidade Nova de Lisboa, Portugal; 6: LBMF, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Portugal; 7: IDMEC, Instituto Superior Técnico, Universidade de Lisboa, Portugal

8:30am - 8:42am
ID: 118 / 4.7: 1

DIGITAL TWINS IN HEALTHCARE: AN ANALYSIS WITHIN THE EU REGULATORY FRAMEWORK

M. Baltuzzi^1,2,3

1: University of Torino, Italy; 2: University of Bologna, Italy; 3: KU Leuven, Belgium

8:42am - 8:54am
ID: 303 / 4.7: 2

ETHICAL AND TECHNICAL FRONTIERS IN VIRTUAL HUMAN TWINS FOR HEALTHCARE

M. BARBIER

National Institute for Research in Digital Science and Technology - INRIA

8:54am - 9:06am
ID: 107 / 4.7: 3

FROM ALGORITHMS TO HEADLINES: MEDIA COVERAGE OF IN SILICO MEDICINE

D. Montesarchio^1,2, Z. Van Horenbeeck^1,2, M. Del Piero²

1: VPH- The Society for In Silico Medicine; 2: KU Leuven

9:06am - 9:18am
ID: 470 / 4.7: 4

THE ZERO-ENTROPY ENVIRONMENT: WHY REGULATION OF DIGITAL TWINS MUST ADDRESS HUMAN AGENCY

V. Prosseda, M. Bertolaso

Università Campus Bio-Medico, Italy

9:18am - 9:30am
ID: 491 / 4.7: 5

IN SILICO METHODOLOGIES IN HIGH-RISK MEDICAL DEVICE DEVELOPMENT: IMPLICATIONS FOR HEALTHCARE SYSTEMS

D. Rösler^1,2, T. Czypionka¹, J. Brüning³, S. Eisenberg¹, M. Kraus¹, M. Reiss¹, C. Zech¹

1: Institute for Advanced Studies Vienna, Department of Health Systems and Health Policy, Austria; 2: University of Vienna, Department of Science and Technology Studies, Austria; 3: Charité Berlin, Institute of Computer-assisted Cardiovascular Medicine, Germany

9:30am - 9:42am
ID: 589 / 4.7: 6

PRIVACY BY DESIGN IN MEDICAL AI: MITIGATING LIFECYCLE RISKS

M. Maouche¹, P. Soda², M. Barbier³

1: National Institute for Research in Digital Science and Technology - INRIA UGA; 2: Research Unit of Artificial Intelligence and Computer Systems, Department of Engineering, Università Campus Bio-Medico di Roma, Italy and Department of Diagnostics and Intervention, Umeå University, Sweeden; 3: National Institute for Research in Digital Science and Technology - INRIA UCA

9:42am - 9:54am
ID: 450 / 4.7: 7

MORE THAN A DATA SUBJECT: RETHINKING PATIENTHOOD IN THE DEVELOPMENT OF MEDICAL DIGITAL TWINS

Z. Van Horenbeeck^1,2, E. Elhadj², E. Lievevrouw², I. Van Hoyweghen²

1: VPH; 2: KU Leuven

9:54am - 9:57am
ID: 393 / 4.7: 8

REAL-TIME PERSONALIZED HEART MODELS FOR HARDWARE IN THE LOOP INTERACTION WITH DEVICES

N. Adhikari¹, B. Allen¹, R. Fenwick-Rose¹, V. Suomi², P. Patel², D. P Nickerson¹, M. L Trew¹, W. Ai¹

1: The University of Auckland, New Zealand; 2: MathWorks, Inc

9:57am - 10:00am
ID: 341 / 4.7: 9

CFD REDUCED-ORDER MODELS FOR INTERACTIVE ASSESSMENT OF CARDIAC HEMODYNAMICS FOR PEDIATRIC SURGERY

B. M. Fanni¹, E. Vignali¹, E. Costa², E. Di Meo³, M. Camponeschi³, V. Carbone⁴, M. E. Biancolini³, S. Celi¹

1: BioCardioLab, Bioengineering Unit, Fondazione Monasterio, Italy; 2: ENGYS, Italy; 3: RBF Morph, Italy; 4: InSilicoTrials Technologies, Italy

10:00am - 10:03am
ID: 304 / 4.7: 10

DIGITAL TWINS AS A “THIRD PARTY” IN CARE: ETHICAL IMPLICATIONS FOR THE PATIENT–DOCTOR RELATIONSHIP

M. BARBIER¹, N. DIE²

1: INRIA, France; 2: DASSAULT SYSTEMES

10:03am - 10:06am
ID: 391 / 4.7: 11

MODEL-BASED DESIGN OF PHYSIOLOGICAL CLOSED-LOOP CONTROL SYSTEMS FOR MEDICAL DEVICES

V. Suomi¹, M. Nord²

1: MathWorks, Germany; 2: MathWorks, France

10:06am - 10:09am
ID: 448 / 4.7: 12

EMBEDDING ETHICS IN INSILICO HEALTH: AN EMPIRICAL ETHICS APPROACH TO VIRTUAL HUMAN TWIN DEVELOPMENT

K. Scheunpflug

Vrije Universiteit Amsterdam, Netherlands, The

10:09am - 10:12am
ID: 647 / 4.7: 13

UNSUPERVISED FAIRNESS ASSESSMENT TO ADDRESS INTERSECTIONALITY AND PROXY FEATURES

E. Beauxis-Aussalet

Vrije Universiteit Amsterdam, Netherlands, The

10:12am - 10:15am
ID: 667 / 4.7: 14

DIGITAL TWINS IN HEALTHCARE. NORMS, EPISTEMOLOGY AND ETHICS IN EUROPE

M. Baltuzzi^1,2,3

1: University of Torino, Italy; 2: University of Bologna, Italy; 3: KU Leuven, Belgium

10:15am - 10:18am
ID: 681 / 4.7: 15

REGIONAL ASSESSMENT OF BRAIN MECHANICAL PROPERTIES DURING AGING

S. Zolghadr¹, N. Reiter¹, J. Hinrichsen¹, L. Hoffmann², S. Rampp³, L. Bräuer⁴, F. Paulsen⁴, S. Budday¹

1: Friedrich-Alexander-University Erlangen-Nuremberg, Germany; 2: Department of Neuropathology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Germany; 3: Department of Neuroradiology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Germany; 4: Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-Nuremberg, Germany

10:18am - 10:21am
ID: 669 / 4.7: 16

INSILICOHEALTH MSCA JOINT DOCTORAL NETWORK: TRAINING VIRTUAL TWIN PROFESSIONALS TO SUPPORT HEALTHY AGEING”

E. Beaucage-Gauvreau¹, R. Castro Viñuelas¹, L. Vangeel¹, I. Jonkers^1,2

1: iSi Health-KU Leuven, Belgium; 2: Department of Movement Sciences, KU Leuven, Belgium

12:00pm - 12:12pm
ID: 131 / 5.1: 1

PREDICTING ADVERSE EVENTS AFTER FROZEN ELEPHANT TRUNK REPAIR USING PATIENT-SPECIFIC FLUID-STRUCTURE INTERACTION SIMULATIONS

Y. Zhu¹, K. Wang¹, A. Awwad², A. Oo², M. Field³, M. Radike³, U. Rosendahl⁴, S. Mirsadraee⁴, X. Y. Xu¹

1: Imperial College London, United Kingdom; 2: Barts Health NHS Trust, United Kingdom; 3: Liverpool Heart and Chest Hospital, United Kingdom; 4: Royal Brompton and Harefield Hospitals, United Kingdom

12:12pm - 12:24pm
ID: 519 / 5.1: 2

ADVANCING ABDOMINAL AORTIC ANEURYSM RISK ASSESSMENT THROUGH ANEURYSM MORPHOLOGICAL CHARACTERIZATION

M. L. Alfarano^1,2, E. Soudah^1,2, M. Aguirre^1,2

1: Universitat Politècnica de Catalunya (UPC), Barcelona, Spain; 2: CIMNE-International Centre for Numerical Methods in Engineering, Barcelona, Spain

12:24pm - 12:36pm
ID: 139 / 5.1: 3

IS THE THIRD BRANCH OPTIMAL? A PATIENT-SPECIFIC FSI ANALYSIS OF TRIPLE-BRANCHED TEVAR

B. Li¹, Y. Zhu^1,2, S. Sica³, M. D'Oria⁴, G. Tinelli³, S. Lepidi⁴, X. Y. Xu¹

1: Department of Chemical Engineering, Imperial College London, United Kingdom; 2: National Heart and Lung Institute, Imperial College London, United Kingdom; 3: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; 4: Department of Medical Surgical and Health Sciences, University of Trieste, Italy

12:36pm - 12:48pm
ID: 441 / 5.1: 4

CORRELATING PATIENT-SPECIFIC RUPTURE RISK WITH NON-INVASIVE DESCRIPTORS IN ASCENDING AORTIC ANEURYSMS

J. Moutinho Gonçalves¹, L. Maes¹, N. Famaey^1,2

1: KU Leuven, Belgium; 2: FIBEr, KU Leuven, Belgium

12:48pm - 1:00pm
ID: 529 / 5.1: 5

CAN IN SILICO GROWTH AND REMODELLING MODELS PREDICT ATAA EVOLUTION?

D. Tarantino¹, S. Pasta^1,2, B. Fantaci³

1: Department of Engineering, Università degli Studi di Palermo, Italy; 2: Department of Research, IRCCS ISMETT, Italy; 3: Aragon Institute of Research Engineering, Universidad de Zaragoza, Spain.

12:00pm - 12:12pm
ID: 352 / 5.2: 1

MODELING THE ROLE OF OBESITY IN KIDNEY DISEASE TREATMENT WITH GLP-1 AGONIST

J. Mallette, R. Hester, J. Clemmer

University of Mississippi Medical Center, Jackson, MS, United States of America

12:12pm - 12:24pm
ID: 399 / 5.2: 2

IN SILICO COMPARISON OF SUBSTRATE-BASED ABLATION STRATEGIES IN STRUCTURAL VENTRICULAR TACHYCARDIA

N. Biasi¹, M. Parollo², D. Vultaggio³, G. Zucchelli², A. Tognetti^1,3

1: Research Center E. Piaggio, University of Pisa, Italy; 2: Second Division of Cardiology, Cardio-Thoracic and Vascular Department, Pisa University Hospital; 3: Information Engineering Department, University of Pisa

12:24pm - 12:36pm
ID: 423 / 5.2: 3

IN SILICO EVALUATION OF TRANSCATHETER TRICUSPID VALVE REPLACEMENT WITH THE EVOQUE SYSTEM

M. Pillitteri¹, A. Zerillo², G. Sausa², S. Pasta^1,2, S. Cannata², C. Gandolfo²

1: University of Palermo, Italy; 2: IRCCS ISMETT, Italy

12:36pm - 12:48pm
ID: 636 / 5.2: 4

EFFICIENT TRANSIENT 0D MICROVASCULAR HEMODYNAMIC MODEL TO INVESTIGATE PERICYTE-INDUCED STALLS.

S. Liu¹, B. Ghitti¹, G. Maso Talou¹, H. Davis², F. Argus¹

1: University of Auckland, New Zealand; 2: University College London, England

12:48pm - 1:00pm
ID: 688 / 5.2: 5

AI-BASED GEOMETRIC AND HEMODYNAMIC BIOMARKERS FOR ABDOMINAL AORTIC ANEURYSM PREDICTION

M. Benovoy¹, A. Guest¹, A. Forneris¹, M. Biglioli², B. B. Ghoshhajra³, G. Soulez⁴, S. C. Muluk⁵, B. W. Starnes⁶, R. D. Moore^1,7, E. S. Di Martino^1,2, A. Satriano¹

1: ViTAA Medical Solutions Inc., Montréal, Québec, Canada; 2: Department of Biomedical Engineering, University of Calgary; 3: Department of Radiology, Harvard Medical School, Boston, Massachusetts, US; 4: Department of Vascular and Interventional Radiology, Centre Hospitalier de l'Université de Montréal, Québec, Canada; 5: Division of Vascular Surgery, AHN Allegheny General Hospital, Pittsburgh, Pennsylvania, US; 6: Division of Vascular Surgery, University of Washington, Seattle, Washington, US; 7: Division of Vascular Surgery, University of Calgary, Calgary, Alberta, Canada

12:00pm - 12:12pm
ID: 140 / 5.3: 1

DEVELOPMENT AND VALIDATION OF AN IN SILICO FRAMEWORK TO PREDICT FRACTURE OF METASTATIC VERTEBRAE

L. Cristofolini¹, G. Barbanti-Bròdano², V. Carbone³, E. Dall'Ara⁴, R. Ferenc⁵, S. J Ferguson⁶, J. M. Garcìa Aznar⁷, N. Germscheid⁸, Á. Lazáry⁹, M. Palanca¹, S. Sale¹⁰, P. Vajkoczy¹¹, J.-J. Verlaan¹², L. Vidacs¹³, E. Voisin¹⁴

1: Alma Mater Studiorum - University of Bologna, Italy; 2: IRCCS Rizzoli Orthopedic Institute, Bologna, Italy; 3: InSilicoTrials Technologies, Italy; 4: University of Sheffield, Sheffield, UK; 5: FrontEndART, Hungary; 6: Federal Institute of Technology ETH Zurich, Switzerland; 7: University of Zaragoza, Spain; 8: AO Foundation, Switzerland; 9: Buda Health Center, Hungary; 10: Eurice, Germany; 11: Charité Universitätsmedizin Berlin, Germany; 12: University Medical Center Utrecht, The Netherland; 13: University of Szeged, Hungary; 14: Voisin Consulting Life Sciences, France

12:12pm - 12:24pm
ID: 175 / 5.3: 2

CIRCADIAN RHYTHMS WITHIN THE INTERVERTEBRAL DISC

L. Baumgartner, J. Noailly

Pompeu Fabra University, Spain

12:24pm - 12:36pm
ID: 212 / 5.3: 3

LESION SIZE AND LOCATION AFFECT THE COMPRESSIVE FAILURE LOAD OF HUMAN METASTATIC VERTEBRAE

R. Roger¹, R. Ghosh¹, Á. Lazáry², L. Guo¹, D. Lacroix¹, E. Dall'Ara¹

1: University of Sheffield, United Kingdom; 2: National Center for Spinal Disorders, Budapest, Hungary

12:36pm - 12:48pm
ID: 213 / 5.3: 4

A BIOMECHANICS-BASED DECISION SUPPORT SYSTEM FOR PREDICTING METASTATIC VERTEBRAL FAILURE RISK

R. Ghosh¹, E. Shearman¹, R. Roger¹, M. Palanca², E. Dall'Ara¹, D. Lacroix¹

1: The University of Sheffield, United Kingdom; 2: Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Italy

12:48pm - 1:00pm
ID: 460 / 5.3: 5

INVERSE OPTIMIZATION OF BONE-TUMOUR INTERFACE AND MATERIAL MAPPING IN METASTATIC VERTEBRAE

J. Muñoz-Allué¹, E. Dall’Ara², M. Palanca³, M. Á. Pérez¹, J. M. García-Aznar¹

1: Aragon Institute of Engineering Research (I3A), University of Zaragoza, Spain; 2: Division of clinical medicine and Insigneo institute, University of Sheffield, United Kingdom; 3: Dept of Industrial Engineering, University of Bologna, Italy

12:00pm - 12:12pm
ID: 543 / 5.4: 1

INTEGRATING IMAGING BIOMARKERS AND RADIOTHERAPY DOSE INTO CARDIOVASCULAR DIGITAL TWINS FOR LONGITUDINAL RISK MODELING

A. Catalano¹, E. Gioscio¹, F. Pisani¹, C. Veronese¹, P. Vallerio¹, L. Dedè², P. Zunino², A. Cicchetti¹

1: Fondazione IRCCS Istituto Nazionale Tumori di Milano, Italy; 2: MOX, Department of Mathematics, Politecnico di Milano, Italy

12:12pm - 12:24pm
ID: 558 / 5.4: 2

PATIENT-SPECIFIC FINITE ELEMENT ANALYSIS OF STENTING FOR SINUS VENOSUS ATRIAL SEPTAL DEFECTS

M. Chatoo¹, N. R. Alonso¹, F. Crasci², S. Schievano¹, G. Giusti³, C. Capelli¹

1: University College London, United Kingdom; 2: Universita’ degli studi di Palermo, Palermo, Italy; 3: Niguarda Hospital, Milan, Italy

12:24pm - 12:36pm
ID: 562 / 5.4: 3

FINITE ELEMENT MODELLING OF PERCUTANEOUS PULMONARY VALVE IMPLANTATION IN PAEDIATRIC ANATOMIES

M. Lecuona¹, L. Swanson¹, A. Salam², S. Khambadkone², G. Giusti³, S. Schievano^1,2, C. Capelli^1,2

1: Institute of Cardiovascular Science, University College London, London; 2: Great Ormond Street Hospital for Children, London; 3: Niguarda Hospital, Milan, Italy

12:36pm - 12:48pm
ID: 537 / 5.4: 4

PATIENT-SPECIFIC MECHANICAL THROMBECTOMY SIMULATION: A CONVERSATION BETWEEN CLINICIANS AND ENGINEERS

T. Brouwer¹, V. Fregona², T. Kuipers¹, L. Bontempi^3,4, F. Gijsen^3,4, H. Marquering¹, J. F. Rodriguez Matas², F. Migliavacca², G. Luraghi², C. Majoie¹

1: Amsterdam UMC, The Netherlands; 2: Politecnico di Milano, Italy; 3: TU Delft, The Netherlands; 4: Erasmus MC, The Netherlands

12:48pm - 1:00pm
ID: 651 / 5.4: 5

ENGINEERING DESIGN CHOICES - A DIRECT PATIENT COMPLICATION RISK

L. Prahl Wittberg¹, M. Broman^2,3

1: Royal Institute of Technology (KTH), Sweden; 2: ECMO Centre Karolinska,Intensive Care and Transport, Pediatric Medicine and Intensive Care, Astrid Lindgren Children’s Hospital, KarolinskaUniversity Hospital, Stockholm, Sweden; 3: Department of Physiology and Pharmacology, Karolinska Institutet,Stockholm, Swede

12:00pm - 12:12pm
ID: 204 / 5.5: 1

BREAKING SILOS WITH DYNAMIC DATA GOVERNANCE

M. Quaranta¹, A. Kremer¹, K. Reiche², A. Funck Hansen³

1: Information Technology for Translational Medicine (ITTM S.A.), Luxembourg; 2: Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany; Interdisciplinary Transformation University (IT:U), Linz, Austria & Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), Dresden, Leipzig, Germany; 3: Fraunhofer Society for the Advancement of Applied Research, Munich, Germany

12:12pm - 12:24pm
ID: 232 / 5.5: 2

TRANSLATING DIGITAL TWIN GLUCOSE PREDICTIONS INTO PATIENT ACTION THROUGH AI BEHAVIOURAL COACHING

K. Nanthakumar, R. Naranpanawa, F. Argus, E. Broadbent, M. Tawhai, G. Maso Talou

University of Auckland, New Zealand

12:24pm - 12:36pm
ID: 284 / 5.5: 3

REGULATORY GAPS AND A LIFECYCLE-BASED FRAMEWORK FOR GENERAL DIGITAL TWINS UNDER THE EU MDR AND AI ACT

C. Welzel, S. Gilbert

Else Kröner Fresenius Center for Digital Health, TUD Dresden University of Technology, Germany

12:36pm - 12:48pm
ID: 518 / 5.5: 4

SPINESIM: A BIOMECHANICAL DIGITAL TWIN FOR SURGERY PLANNING AND BIOMECHANICAL ANALYSIS

M. Tarquini, M. Rasouligandomani, S. T. Dukkipati, D. Kaçar, R. Assaker, L. Adam

MDsim, Luxembourg

12:48pm - 1:00pm
ID: 320 / 5.5: 5

TOWARDS QUALIFICATION AND REGULATORY ACCEPTANCE OF VIRTUAL CONTROL GROUPS (VCGS) - THE IHI VICT3R PROJECT

T. Steger-Hartmann¹, K. Kopanska^2,3, F. Sanz⁴, F. Bringezu⁵, I. Soininen⁶

1: Bayer AG, Germany; 2: John Hopkins University; 3: CAATevents gGmbH; 4: Universitat Pompeu Fabra; 5: Merck Healthcare KGaA; 6: SYNAPSE Research Management Partners

12:00pm - 12:12pm
ID: 184 / 5.6: 1

PORTAL THROMBOSIS FOLLOWING MAJOR LIVER SURGERY: THE IMPACT OF HEMODYNAMIC SHEAR

M. Garreau¹, A. Vlasceanu^1,2,3, A. Facque³, G. Cardillo⁴, A. I. Barakat⁴, N. Golse², I. Vignon-Clementel⁴

1: INRIA Saclay, France; 2: Centre Hépato-Biliaire - Hôpital Paul Brousse, AP-HP, France; 3: CHRU Tours, France; 4: LadHyX, CNRS, Ecole Polytechnique, IP Paris, France

12:12pm - 12:24pm
ID: 270 / 5.6: 2

AGEING AS A SCAR: REDEFINING AGEING AS AN ACCUMULATION OF SMALL DAMAGES DURING LIFETIME

P.-A. Grott¹, M. Ousset¹, A. Lorsignol¹, L. Casteilla¹, P. Monsarrat¹, D. Peurichard², J. Paupert¹

1: RESTORE Research Center; 2: Inria Paris

12:24pm - 12:36pm
ID: 406 / 5.6: 3

DISRUPTED BRAIN DYNAMICS IN EARLY PARKINSON’S DISEASE: TOWARD DIGITAL BIOMARKERS AND BRAIN DIGITAL TWINS

D. Pischedda¹, M. Vitacca¹, F. Palesi^1,2, A. Tessitore³, R. De Micco³, M. Siciliano³, F. Esposito³, C. A. Gandini Wheeler-Kingshott^1,2,4, E. D'Angelo^1,2

1: Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; 2: Digital Neuroscience Centre, IRCCS Mondino Foundation, Pavia, Italy; 3: Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy; 4: Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Queen Square Multiple Sclerosis Centre, NMR Research Unit, London, UK

12:36pm - 12:48pm
ID: 536 / 5.6: 4

CARDIACFOAM: TOWARDS A FRAMEWORK FOR IN-SILICO INSIGHTS INTO PIG-TO-HUMAN HEART XENOTRANSPLANTATION

S. Nieto de Castro¹, P. Castrillo^1,2, C. Cownay³, P. Cardiff¹

1: School of Mechanical & Materials Engineering, University College Dublin, Ireland.; 2: Instituto de Estructuras y Transporte, Universidad de la República, Uruguay.; 3: Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Ireland

12:48pm - 1:00pm
ID: 608 / 5.6: 5

A NOVEL ELECTROMECHANICAL MODEL OF THE MEDIAN NERVE WITH APPLICATION TO CARPAL TUNNEL SYNDROME

J. Rittelmann, O. Röhrle, C. Bleiler

Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Germany

12:00pm - 12:12pm
ID: 113 / 5.7: 1

NEUROANATOMY ATLAS AS A CORE FOR VIRTUAL BRAIN TWIN: SHARING THREE-DECADE-LONG EXPERIENCE

W. Nowinski

Sano Center for Computational Personalised Medicine, Poland

12:12pm - 12:24pm
ID: 319 / 5.7: 2

CERTAINTY: A CELLULAR IMMUNOTHERAPY VIRTUAL TWIN FOR PERSONALISED CANCER TREATMENT

M. Kreuz¹, U. Weirauch¹, M. Quaranta², A. Kremer², S. Franke³, H. Fröhlich⁴, Y. Salimi⁴, S. Schwick⁴, M. Merz⁵, R. Demlova⁶, C. Steinbeisser⁷, K. Reiche^1,8

1: Fraunhofer IZI, Leipzig, Germany; 2: Information Technology for Translational Medicine, Esch-sur-Alzette, Luxembourg; 3: ICCAS, Universität Leipzig, Leipzig, Germany; 4: Fraunhofer SCAI, Sankt Augustin, Germany; 5: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, USA; 6: Faculty of Medicine, Masaryk University, Brno, Czechia; 7: Collaborate Project Management, Munich, Germany; 8: Interdisciplinary Transformation University (IT:U), Linz, Austria

12:24pm - 12:36pm
ID: 444 / 5.7: 3

INTEGRATION OF SINGLE‑CELL RNA-SEQ DATA INTO VIRTUAL TWINS FOR MULTIPLE MYELOMA CAR-T CELL THERAPY

C. Kämpf¹, G. Popp¹, J. Keller², A. Scholz^1,3, N. Seeger¹, M. Quaranta⁴, R. Tching⁴, M. Merz^1,5,6, S. Franke², K. Reiche^1,3,7,8,9

1: Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany; 2: Innovation Center Computer Assisted Surgery (ICCAS), Leipzig, Germany; 3: Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany; 4: Information Technology for Translational Medicine, Esch-sur-Alzette, Luxembourg; 5: Myeloma and Cellular Therapy Services, Memorial Sloan Kettering Cancer Center, New York, NY, USA; 6: Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany; 7: Interdisciplinary Transformation University (IT:U), Linz, Austria; 8: Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), Dresden, Leipzig, Germany; 9: Zuse School of Embedded and Composite AI (SECAI) Dresden-Leipzig, Germany

12:36pm - 12:48pm
ID: 484 / 5.7: 4

I-OPADE: A MULTIMODAL BIOMARKER PLATFORM ENABLING DIGITAL TWIN-BASED PRECISION PSYCHIATRY

L. Androutsos¹, A. Floares¹, A. Zety¹, S. Naseer¹, M. Mohsin¹, G. Corrivetti², A. Marenna², R. Panella², C. Vecchi², F. Monao², A. Vignapiano², C. Floares¹, K. Palm³, T. Timmusk³, A. Sirp³, M. Piirsalu³, M. Annuk³, A. Rahni³, R. Maruste³, H.-Y. Chiang⁴, F. Zucchi⁴, M. A. Isaza Ruget⁵, C. Aristizábal Guzmán⁵, J. Mcdouall Lombana⁵, J. A. Castro Munoz⁵, M. A. Palacios Ariza⁵, E. Frigola-Capell⁶, G. Brugues⁶, A. Maestre⁶, J. Serrano⁶, R. Brugada⁶, A. Brugada⁶, M. Coll⁶, L. Lopez⁶, P. Hajduk⁷, A. Szymanek⁷, A. Bouwens⁷, P. Carmellini⁸, A. Fagiolini⁸, M. M. ŞİMŞEK⁹, A. Kılıç⁹, İ. KÖSE⁹, R. Visconti¹⁰, M. Cuomo¹⁰, C. Martinez Carazo¹¹, O. Ibarrola Moreno¹¹

1: ARTIFICIAL INTELLIGENCE EXPERT, Greece; 2: EBRIS, Italy; 3: PROTOBIOS, Esthonia; 4: CEPHALGO; 5: FUS, Colombia; 6: IDIBGI, Spain; 7: PERSEUS BIOMICS, Belgium; 8: UNISI, Italy; 9: IMU, Turkey; 10: CEINGE, Italy; 11: BIOKERALTY, Spain

12:48pm - 1:00pm
ID: 449 / 5.7: 5

A DATA INTEGRATION PIPELINE COMBINING FUNCTIONAL DATA ANALYSIS WITH MULTI-LAYER CORRELATION NETWORK

R. Asnaghi, A. Morabito, M. Carrara, M. Ferrario

Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Milano, Italy

4:30pm - 4:42pm
ID: 166 / 6.1: 1

BIOMECHANICAL EFFECT OF PERCUTANEOUS PULMONARY VALVE POSITIONING IN PATIENT-SPECIFIC MODELS

M. Arminio¹, D. Gallo¹, D. Carbonaro^1,2, R. Paz^3,4, F. Del Pin³, U. Morbiducci¹, S. Schievano^5,6, C. Chiastra¹, C. Capelli^5,6

1: Politecnico di Torino, Italy; 2: University of Calabria, Italy; 3: Ansys/Synopsys, Inc., California, USA; 4: CONICET, National Council for Scientific and Technical Research, Argentina; 5: University College London, UK; 6: Great Ormond Street Hospital for Children, UK

4:42pm - 4:54pm
ID: 183 / 6.1: 2

PATIENT-SPECIFIC COMPUTATIONAL FLUID DYNAMICS BEFORE AND AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION

L. Bevis¹, Y. Bhatti^1,2, E. Rauseo^1,2, E. Karabelas^3,4, X. Chen¹, R. Burns¹, A. Khan¹, S. E Petersen¹, C. M Augustin⁵, A. Neic³, G. Plank^3,5, C. H Roney¹, G. Slabaugh¹, A. Mathur^1,2

1: Queen Mary University of London, United Kingdom; 2: Barts Health NHS Trust, United Kingdom; 3: Numericor Gmbh, Austria; 4: BioTechMed-Graz, Austria; 5: Medical University of Graz, Austria

4:54pm - 5:06pm
ID: 291 / 6.1: 3

TOWARDS PATIENT-SPECIFIC VENTRICLE-TAVI INTERACTION: A VALIDATED ELECTROMECHANICAL MODEL OF LEFT VENTRICLE

B. Grossi^1,2,3, L. Cestariolo³, C. Boccaperta Schiavetti³, T. Casini³, L. M. Perri^1,3, G. Stefanini^1,2, G. Condorelli^1,2, G. Luraghi³, F. Migliavacca^3,4, J. F. Rodriguez Matas³

1: Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy; 2: IRCCS Humanitas Research Hospital, Via Alessandro Manzoni 56, 20089 Rozzano, Milan, Italy; 3: Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milan, Italy; 4: Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza, 35, 20122 Milan, Italy.

5:06pm - 5:18pm
ID: 327 / 6.1: 4

IN-SILICO HEMODYNAMIC MODEL FOR THE ASSESSMENT OF MITRAL REGURGITATION QUANTIFICATION METHODS

I. Vervaeke¹, J. Degroote¹, A. Caenen^1,2, P. Segers¹

1: Ghent University, Belgium; 2: KU Leuven, Belgium

5:18pm - 5:30pm
ID: 475 / 6.1: 5

AN IN-SILICO STUDY ON THE IMPACT OF INDIVIDUAL GEOMETRICAL FEATURES FOR PREDICTING HEART VALVE FUNCTION

P. Yevtushenko¹, K. Vellguth¹, L. Goubergrits¹, M. Schafstedde^1,2

1: Charité-Universitätsmedizin Berlin, Germany; 2: Berlin Institute of Health

5:30pm - 5:42pm
ID: 553 / 6.1: 6

PATIENT-SPECIFIC HAEMODYNAMIC DIGITAL TWIN WITH PATHOLOGICAL VALVE DYNAMICS

A. J. Escobar¹, O. Chehab^1,2, T. Patterson^1,2, J. Lee¹

1: King's College London, United Kingdom; 2: St Thomas' Hospital, London, United Kingdom

5:42pm - 5:54pm
ID: 580 / 6.1: 7

A MITRAL VALVE DIGITAL TWIN FOR SURGICAL PLANNING

M. Sacks

Unversity of Texas at Austin, United States of America

4:30pm - 4:42pm
ID: 133 / 6.2: 1

UNCERTAINTY AND SENSITIVITY IN VENOUS MODELLING ACROSS 0D, 3D AND STATISTICAL SHAPE FRAMEWORKS

M. Otta^1,2, K. Zając¹, I. Halliday², C. Lim³, J. Tsui^3,4, M. Malawski^1,5, A. Narracott²

1: Sano Centre for Computational Medicine, Poland; 2: University of Sheffield, UK; 3: Royal Free Hospital, UK; 4: University College London, UK; 5: AGH University of Kraków, Poland

4:42pm - 4:54pm
ID: 633 / 6.2: 2

TOWARDS HEPATIC DIGITAL TWINS: MULTISCALE-MULTIPHYSICS MODELING AND VALIDATION OF LIVER REGENERATION

J. Hohl, A. Ebrahem, E. Jessen, D. Schillinger

Technical University of Darmstadt, Germany

4:54pm - 5:06pm
ID: 457 / 6.2: 3

CORONARY DIGITAL TWIN GENERATION FROM ULTRA HIGH-RESOLUTION PHOTON-COUNTING CT: AN ITERATIVE APPROACH

A. Arcangeli, K. Capellini, A. Aimo, M. Emdin, M. Occhipinti, M. Muca, F. Pignatelli, A. Clemente, V. Positano, S. Celi, C. De Gori

Fondazione Gabriele Monasterio, Italy

5:06pm - 5:18pm
ID: 369 / 6.2: 4

MICROSTRUCTURE-DRIVEN IN SILICO MACHINE LEARNING MODEL FOR PHOTOACOUSTIC THROMBUS CHARACTERIZATION

H. Ghodsi¹, S. Kumar², B. Fereidoonnezhad³, S. Iskander-Rizk¹

1: Department of Precision and Microsystems Engineering, Faculty of Mechanical Engineering, Delft University of Technology, Delft, The Netherlands; 2: Department of Materials Science and Engineering, Delft University of Technology, The Netherlands; 3: Department of BioMechanical Engineering , Faculty of Mechanical Engineering, Delft University of Technology, The Netherlands

5:18pm - 5:30pm
ID: 478 / 6.2: 5

A COMPUTATIONAL MODEL OF CHEMICALLY- AND MECHANICALLY-INDUCED THROMBUS FORMATION IN CEREBRAL ANEURYSMS

G. Cardillo¹, P. Pouponneau², A. I. Barakat¹

1: Ecole Polytechnique, Institut Polytechnique de Paris,Palaiseau, France; 2: Artedrone Microrobots Cerebral Vascular, Paris, France

5:30pm - 5:42pm
ID: 525 / 6.2: 6

WITHIN LIVER VASCULAR NETWORKS: QUANTIFYING THE INTERPLAY BETWEEN GEOMETRY AND TRANSPORT

J. Kowalski¹, L. Sala², D. Drasdo¹, C. Debbaut³, I. Vignon-Clementel¹

1: Inria Saclay, Palaiseau, France; 2: Université Paris-Saclay, INRAE, Jouy-en-Josas, France; 3: Ghent University, Ghent, Belgium

5:42pm - 5:54pm
ID: 600 / 6.2: 7

MODELLING HAEMORRHAGE AND PHYSIOLOGICAL RESPONSE IN PENETRATING TRAUMA

A. Jayakody¹, V. Suresh^1,2, F. Argus¹

1: Auckland Bioengineering Institute, University of Auckland, New Zealand; 2: Department of Engineering Science and Biomedical Engineering, University of Auckland, New Zealand

4:30pm - 4:42pm
ID: 256 / 6.3: 1

LINKING CORONARY MORPHOLOGY TO CARDIAC ALLOGRAFT VASCULOPATHY THROUGH STATISTICAL SHAPE MODELLING

B. Griffo¹, C. Fogarasi², M. Lodi Rizzini¹, A. Aldieri³, D. Gallo¹, M. Laudato⁴, H. Bille Andersson², J. Jurga², M. Melin², J. Nickander², D. Marlevi², U. Morbiducci¹

1: Politecnico di Torino, Turin, Italy; 2: Karolinska Institute, Solna, Sweden; 3: University of Bologna, Bologna, Italy; 4: KTH Royal Institute of Technology, Stockholm, Sweden

4:42pm - 4:54pm
ID: 283 / 6.3: 2

HEMODYNAMIC CHARACTERIZATION OF ATHEROSCLEROTIC CAROTID BIFURCATION

V. Quartieri¹, F. Harte², A. Mastrofini⁴, E. Karlöf³, U. Hedin³, M. Marino⁴, T. C. Gasser¹

1: Royal Institute of Technology, Sweden; 2: Eindhoven University of Technology, Netherlands; 3: Karolinska Institute, Sweden; 4: University of Rome Tor Vergata, Italy

4:54pm - 5:06pm
ID: 418 / 6.3: 3

THE POTENTIAL OF SOUND ANALYSIS FOR THE SURVEILLANCE OF HEMODIALYSIS ARTEROVENOUS FISTULAE

S. Poloni¹, S. Zerbi², C. Ghilardini², L. Soliveri³, C. G. Condemi², A. Caroli¹, A. Remuzzi³, M. Bozzetto¹

1: Department of Biomedical Engineering, Istituto di Ricerche Farmacologiche Mario Negri, Italy; 2: Unit of Nephrology and Dialysis, ASST Papa Giovanni XXIII, Italy; 3: Department of Management, Information and Production Engineering, Università degli Studi di Bergamo, Italy

5:06pm - 5:18pm
ID: 425 / 6.3: 4

IMPROVING ONE-YEAR SURVIVAL FORECASTING IN PULMONARY ARTERIAL HYPERTENSION USING MACHINE LEARNING MODELS

N. Wang¹, Z. M. Goh^1,2, H. Saxton⁶, M. Paula-Ribeiro^1,2, J. Longbottom¹, M. Balmus^3,4, A. Rothman^1,2, M. Wilkins⁴, R. Wilkinson⁵, K. Worden¹, D. Wagg¹, S. Niederer^3,4, X. Xu¹, R. Clayton¹

1: University of Sheffield, UK; 2: Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, UK; 3: The Alan Turing Institute, UK; 4: Imperial College London, UK; 5: School of Mathematical Sciences, University of Nottingham, UK; 6: Astellas Pharma, UK

5:18pm - 5:30pm
ID: 462 / 6.3: 5

FAST COMPUTATIONAL FRAMEWORK FOR PATIENT-SPECIFIC TEVAR PLANNING

S. Barati¹, A. Stellino¹, G. De Campo¹, A. Ramella¹, G. Luraghi¹, J. F. Rodriguez Matas¹, I. Fulgheri², S. Trimarchi^2,3, F. Migliavacca^1,2

1: Politecnico di Milano, Italy; 2: IRCCS Policlinico di Milano, Italy; 3: Università degli Studi di Milano, Italy

5:30pm - 5:42pm
ID: 280 / 6.3: 6

SYNCHROTRON PHASE-CONTRAST TOMOGRAPHY REVEALS MYOCARDIAL ORGANISATION IN FETAL AORTIC STENOSIS

L. Chestnutt^1,2, J. Brunet^1,3, H. Dejea^3,4, V. Sabarigirivasan², K. Y. C. Li², A. Bonnin⁵, M. Olbinado^4,5, B. Bijnens⁶, M. Jongbloed⁷, L. Houyel⁸, A. Crucean⁹, P. D Lee¹, A. Cook²

1: Department of Mechanical Engineering, University College London, United Kingdom; 2: Institute of Cardiovascular Science, University College London, United Kingdom; 3: The European Synchrotron, ESRF, France; 4: Anaxam, Switzerland; 5: Paul Scherrer Institute, Switzerland; 6: ICREA - Universitat Pompeu Fabra, Spain; 7: Leiden University Medical Center, The Netherlands; 8: Necker–Enfants Malades Hospital, France; 9: Birmingham Women’s and Children’s Hospital NHS Trust, United Kingdom

5:42pm - 5:54pm
ID: 616 / 6.3: 7

SIMSCAPE-BASED CARDIOVASCULAR MODELS FOR NEXT‑GENERATION ECMO SYSTEM DEVELOPMENT

M. Nord¹, V. Suomi²

1: MathWorks, France; 2: MathWorks, Germany

4:30pm - 4:42pm
ID: 461 / 6.4: 1

TOWARDS A DIGITAL TWIN FOR PERSONALIZED PREDICTION OF RADIOTHERAPY RESPONSE OF PROSTATE CANCER

B. Blanco¹, M. A. Vicente Pardal², H. Gomez³, G. Lorenzo²

1: Universidade de Santiago de Compostela, Spain; 2: Universidade da Coruña, Spain; 3: Purdue University, USA

4:42pm - 4:54pm
ID: 226 / 6.4: 2

A CAUSAL COMPUTATIONAL FRAMEWORK FOR DIGITAL TWINS IN BREAST CANCER RADIOTHERAPY

F. Arceci¹, P. Vitullo¹, B. Dionisi Ferrera², M. Tezzele³, P. Zunino¹, T. Rancati²

1: Politecnico di Milano, Italy; 2: Fondazione IRCCS Istituto Nazionale dei Tumori, Italy; 3: Emory University, Atlanta

4:54pm - 5:06pm
ID: 296 / 6.4: 3

ENABLING CLINICAL PROGNOSIS OF BREAST CANCER DURING NEOADJUVANT THERAPIES

F. Lovallo², M. V. De Bonis¹, G. Ruocco^1,2

1: iBMB Srls, University of Basilicata, Italy; 2: DiING, University of Basilicata, Italy

5:06pm - 5:18pm
ID: 300 / 6.4: 4

PBPK‑DRIVEN OPTIMIZATION OF CAR‑T DELIVERY AND EFFICACY

A. G. Hadjigeorgiou¹, L. L. Munn², T. Stylianopoulos¹, R. K. Jain²

1: University of Cyprus, Cyprus; 2: Massachusetts General Hospital / Harvard Medical School, USA

5:18pm - 5:30pm
ID: 365 / 6.4: 5

TRI-PHASIC REPROGRAMMING OF THE SPHINGOSINE-1-PHOSPHATE AXIS DRIVES OVARIAN CANCER PROGRESSION AND ANOIKIS RESISTANCE

A. S. Baskin^1,2, B. Davidson³, R. Reich², T. Tavor Re'em¹

1: Azrieli College of Engineering in Jerusalem, Israel; 2: The Hebrew University of Jerusalem; 3: The Medical Faculty, University of Oslo, Oslo, Norway

5:30pm - 5:42pm
ID: 412 / 6.4: 6

REALISTIC IN SILICO TUMOUR SUBSTRATES FOR DW-MRI SIMULATIONS

C. Scotti, C. Tinelli, F. Casaccio, P. Fenech, G. Baroni, L. Morelli, C. Paganelli

Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Italy

5:42pm - 5:54pm
ID: 465 / 6.4: 7

PATIENT-SPECIFIC IN SILICO 3D MODEL OF BRAIN METASTASIS TREATMENT IN RESPONSE TO STEREOTACTIC RADIOSURGERY

E. Ioannou¹, C. P. Papanikas¹, D. Flouri¹, L. Siakallis¹, G. Karaoli², E. Papageorgiou², M. Theodorou², V. Vavourakis^1,3

1: University of Cyprus, Cyprus; 2: Bank of Cyprus Oncology Centre, Cyprus; 3: University College London, UK

4:30pm - 4:42pm
ID: 161 / 6.5: 1

UNRESOLVED CFD-DEM MODELING OF PLATELETS DYNAMICS ACCOUNTING FOR ACCURATE PARTICLE SHAPE

F. Zucchelli, J. Latt, B. Chopard

University of Geneva, Switzerland

4:42pm - 4:54pm
ID: 210 / 6.5: 2

VIRTUAL PATIENTS FOR MECHANISTIC MODEL DISCOVERY IN VASCULAR MECHANOBIOLOGY

A. Mastrofini, M. Marino

University of Rome Tor Vergata, Italy

4:54pm - 5:06pm
ID: 202 / 6.5: 3

GRAPH-DERIVED MECHANOCHEMICAL SIMULATIONS CAPTURE VARIABILITY IN ATHEROSCLEROSIS PROGRESSION

A. Mastrofini¹, A. Tziotziou², D. Bos^2,3, A. C. Akyildiz^3,4, M. Marino¹

1: Multiscale and Multiphysics Mechanics Group (M2M), Department of Civil Engineering and Computer Science Engineering, University of Rome Tor Vergata, Rome, Italy; 2: Department of Cardiology, Biomedical Engineering, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, Netherlands, Netherlands; 3: Department of Radiology & Nuclear Medicine, Erasmus Medical Center, Rotterdam, Netherlands; 4: Multiscale and Multiphysics Mechanics Group (M2M), Department of Civil Engineering and Computer Science Engineering, University of Rome Tor Vergata, Rome, Italy

5:06pm - 5:18pm
ID: 242 / 6.5: 4

MODELLING THE TRANSPORT OF OXYGEN AND CARBON DIOXIDE IN THE HUMAN VASCULAR SYSTEM

M. Viharos, R. Wéber

Department of Hydrodynamic Systems, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, 1111, Hungary

5:18pm - 5:30pm
ID: 244 / 6.5: 5

FROM GLOBAL HAEMODYNAMICS TO SARCOMERE MECHANICS: AN IN-SILICO MODEL APPLIED TO DILATED CARDIOMYOPATHY

A. Kamtikar¹, D. Donker^1,2, L. Fresiello¹

1: University of Twente; 2: University Medical Centre, Utrecht

5:30pm - 5:42pm
ID: 377 / 6.5: 6

A MULTI-SCALE APPROACH TO MODELING SWIRLING BLOOD FLOW IN THE LEFT HEART AND AORTA

A. Gorodkov¹, Y. Zharkov¹, E. Talyguin¹, I. Beglov², A. Agafonov¹, N. Chernykh¹

1: Bakulev National Research Centre for Cardiovascular Surgery, Russian Federation; 2: MIREA – Russian Technological University, Moscow, Russian Federation

5:42pm - 5:54pm
ID: 437 / 6.5: 7

CFD-ABM FRAMEWORK QUANTIFIES MONOCYTE NLRP3 INFLAMMASOME ACTIVATION HOTSPOTS DRIVEN BY ARTERIAL LOW-SHEAR HEMODYNAMICS

V. V. S. V. Jakka, M. Sarkissian, Y. M. Alemu, J. Noailly

Universitat Pompeu Fabra (UPF), Spain

4:30pm - 4:42pm
ID: 188 / 6.6: 1

PATIENT-SPECIFIC ATRIAL MODELS CALIBRATED WITH CLINICAL LOCAL ACTIVATION MAPS FROM TRIPLE-EXTRA PACING

D. De Luis Moura¹, C. Celotto², S. Golmaryami³, M. Termenón-Rivas¹, G. S Romitti¹, E. Silva³, J. Fernandez-Armenta³, J. F. Rodriguez², A. Liberos¹, M. Rodrigo¹

1: Universidad de Valencia, Spain; 2: Department of Chemistry Giulio Natta, Politecnico di Milano, Milán; 3: Departamento de Cardiología, Hospital Universitario Puerta del Mar, Cádiz, España

4:42pm - 4:54pm
ID: 348 / 6.6: 2

A GRAPH NEURAL FRAMEWORK FOR FULL-CYCLE VENTRICULAR MYOCARDIAL FINITE ELEMENT BIOMECHANICS SIMULATIONS

S. Mu, W. X. Chan, C. H. Yap

Imperial College London, Dept of Bioengineering, London, United Kingdom

4:54pm - 5:06pm
ID: 443 / 6.6: 3

VALIDATION OF A COMPUTATIONAL MODEL FOR CARDIAC PERFUSION IN MYOCARDIAL ISCHEMIA DETECTION

V. Cusumano^1,2, R. Maragna¹, E. Ventura¹, G. Nannini³, G. Pontone¹, C. Vergara²

1: Centro Cardiologico Monzino, IRCCS, Milano, Italy; 2: LaBS, Dipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta", Politecnico di Milano, Milano, Italy; 3: Dipartimento di Elettronica Informazione e Bioingeneria, Politecnico di Milano, Milano, Italy

5:06pm - 5:18pm
ID: 445 / 6.6: 4

TOWARDS THE VALIDATION OF PATIENT-SPECIFIC LEFT ATRIAL CFD SIMULATIONS: A COMPARATIVE PIV STUDY

I. Verdirame^1,2, E. Gasparotti¹, E. Vignali¹, B. M. Fanni¹, S. Celi¹

1: BioCardioLab, Bioengineering Unit, Fondazione Monasterio, Massa, Italy; 2: Department of Information Engineering, University of Pisa, Pisa, Italy

5:18pm - 5:30pm
ID: 455 / 6.6: 5

A V&V40-ALIGNED CREDIBILITY FRAMEWORK FOR REGULATORY-GRADE LEFT ATRIAL APPENDAGE OCCLUDER IN-SILICO TRIALS

O. Camara

Universitat Pompeu Fabra, Spain

5:30pm - 5:42pm
ID: 521 / 6.6: 6

TOWARDS CREDIBLE ECG-BASED VENTRICULAR DIGITAL TWINS: UNCERTAINTY-AWARE LIMITS OF CONDUCTION-SUBSTRATE DETECTABILITY

J. Camps, O. Camara

Universitat Pompeu Fabra, Spain

5:42pm - 5:54pm
ID: 604 / 6.6: 7

AUTOMATED CREDIBILITY ASSESSMENT: A MODEL-AGNOSTIC PIPELINE APPLIED TO CARDIAC DIGITAL TWINS

S. A. Creamer¹, A. Sharifzadeh-Kermani^1,2, F. J. Argus¹, D. Zhao¹, M. P. Nash^1,3, D. P. Nickerson¹

1: Auckland Bioengineering Institute, University of Auckland, New Zealand; 2: Mātai Medical Research Institute, New Zealand; 3: Department of Engineering Science and Biomedical Engineering, University of Auckland, New Zealand

4:30pm - 4:42pm
ID: 126 / 6.7: 1

TRANSITION-LIKELIHOOD SURROGATES FOR CALIBRATING ORGAN-ON-CHIP AND TUMOUR-ON-CHIP CELL TRAJECTORIES

F. Spill, Z. Wu, B. Cardoen, H. Lyu, J. Andrews, S. Wang

University of Birmingham, United Kingdom

4:42pm - 4:54pm
ID: 219 / 6.7: 2

COMPUTATIONAL MODELING OF TUMOR-ON-CHIP ORGANOIDS: LINKING MECHANICS AND METABOLISM

P. Garcia-Gomez¹, P. Guerrero-Lopez¹, S. Hervas-Raluy², J. M. Garcia-Aznar¹

1: Universidad de Zaragoza, Spain; 2: Technical University of Munich

4:54pm - 5:06pm
ID: 463 / 6.7: 3

SYNCHRONIZING EXPERIMENTAL AND COMPUTATIONAL MODELS OF ENDOTHELIAL BARRIER FAILURE

Ó. Paseta¹, A. Martín-Contreras¹, A. González-Loyola^2,3, J. M. García-Aznar¹, M. J. Gómez-Benito¹

1: Multiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.; 2: Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; 3: Aragonese Agency Foundation for Research and Development (ARAID).

5:06pm - 5:18pm
ID: 504 / 6.7: 4

SIMULATING THE FOREIGN BODY RESPONSE WITH AN AGENT-BASED MODELING APPROACH

J. Riccio, L. Presotto, G. Chirico

University of Milano-Bicocca, Italy

5:18pm - 5:30pm
ID: 528 / 6.7: 5

COMPUTATIONAL MODELING OF PROTEIN ACCUMULATION AND MIGRATION IN THE CNS IN THE CONTEXT OF EPILEPSY

L. Ribeiro¹, E. Toscano², M. Lobosco^1,3, B. Quintela^1,3

1: Computer Science Department, Federal University of Juiz de Fora, Brazil; 2: Pharmacology Department, Federal University of Juiz de Fora, Brazil; 3: Computational Modeling Graduate Program, Federal University of Juiz de Fora, Brazil

5:30pm - 5:42pm
ID: 637 / 6.7: 6

MECHANICAL LOADING ORGANIZES DISTINCT REGULATORY AT-TRACTOR STATES IN NUCLEUS PULPOSUS CELLS

Z. WORKINEH, J. Noailly

Universitat Pompeu Fabra, Spain

5:42pm - 5:54pm
ID: 653 / 6.7: 7

AUTOMATED IMAGE-BASED RECONSTRUCTION OF 3D SUBCELLULAR STRUCTURES FOR FINITE ELEMENT MODELING

W. Li, C. Wang, F. Zhao

Zienkiewicz Institute for Modelling, Data & AI, Faculty of Science & Engineering, Swansea University, UK