Conference Agenda

11:00am - 11:12am
ID: 108 / 1.1: 1

ASSESSMENT OF THE PREDICTIVE PERFORMANCE OF A FLUID-STRUCTURE-GROWTH MODEL FOR ASCAA

K. Yan^1,2,3, W. Ye¹, A. Martinez¹, L. Geronzi⁴, P. Escrig², J. Tomasi², M. Rochette¹, P. Haigron², A. Bel-Brunon³

1: ANSYS, 69621 Villeurbanne, France; 2: Univ Rennes, CHU Rennes, Inserm, LTSI – UMR 1099, F-35000 Rennes, France; 3: Univ Lyon, Univ Gustave Eiffel, Univ Claude Bernard Lyon 1, LBMC UMR_T 9406, F-69622 Lyon, France; 4: Department of Enterprise Engineering “Mario Lucertini”, University of Rome “Tor Vergata”, Rome, Italy

11:12am - 11:24am
ID: 246 / 1.1: 2

AN EXPERIMENTALLY VALIDATED INVERSE APPROACH FOR PATIENT-SPECIFIC CHARACTERIZATION OF AAA MECHANICS

G. Caruso¹, A. Guala^3,4, L. Dux-Santoy³, G. Teixidó-Turà^3,5, J. F. Rodriguez-Palomares^3,4,5, M. Bragulat-Arévalo^3,4, S. Bellmunt⁵, M. García-Reyes⁵, M. A. Martínez^1,2, E. Peña Baquedano²

1: Universidad de Zaragoza, Spain; 2: CIBER-BBN, Centro de Investigación en Red en Bioingeniería, Spain; 3: Vall d’Hebron Institut de Recerca, Barcelona, Spain; 4: Biomedical Research Networking Center on Cardiovascular Diseases, CIBER-CV, Instituto de Salud Carlos III, Madrid, Spain; 5: Department of Vascular Surgery, Hospital Universitari Vall d’Hebron, Barcelona, Spain

11:24am - 11:36am
ID: 384 / 1.1: 3

PREDICTING HEMODYNAMICS FROM AORTIC GEOMETRY

J. Marín¹, A. Bayón², F. Martínez-Gil¹, P. Romero^1,3, M. Lozano¹, I. García-Fernández¹

1: CoMMLab – Computational Multiscale Simulation Lab, University of Valencia, Spain.; 2: Department of Hydraulic and Environmental Engineering, Universitat Politècnica de València, Spain.; 3: Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.

11:36am - 11:48am
ID: 482 / 1.1: 4

EXPERIMENTALLY VALIDATED COMPUTATIONAL MODELLING OF FLOW REVERSAL IN TYPE B AORTIC DISSECTION

M. Correnti^1,2, M. Roy³, S. Di Leonardo^1,2, A. Monteleone¹, R. P. Lim^4,5, A. Ooi⁶, G. Micale², S. Chakraborty^3,7, G. Burriesci^1,2,8

1: Ri.MED Foundation, Palermo, Italy; 2: Università degli Studi di Palermo, Italy; 3: School of Medical Science and Technology, Indian Institute of Technology Kharagpur, India; 4: Department of Radiology, Austin Health, Australia; 5: Departments of Radiology and Surgery, The University of Melbourne, Australia; 6: Department of Mechanical Engineering, The University of Melbourne, Australia; 7: Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, India; 8: UCL Mechanical Engineering, University College London, UK

11:48am - 12:00pm
ID: 193 / 1.1: 5

PREDICTING POST-TEVAR ENDOLEAKS: A PRE-OPERATIVE RISK FACTOR FROM FLUID-STRUCTURE INTERACTION SIMULATIONS

F. Duca¹, S. Tavarone¹, M. Domanin^2,3, D. Bissacco^2,3, S. Trimarchi^2,3, F. Migliavacca^1,3, C. Vergara¹

1: LaBS, Dipartimento di Chimica, Materiali e Ingegneria Chimica, Politecnico di Milano, Italy; 2: Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Italy; 3: Section of Vascular Surgery, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico Milano, Italy

12:00pm - 12:12pm
ID: 641 / 1.1: 6

A CFD-LABELLED SYNTHETIC DATASET OF HAEMODYNAMICS IN ABDOMINAL AORTIC ANEURYSM

V. Nandurdikar¹, T. Canchi², A. Revell¹, A. Frangi^1,3, A. B Harish¹

1: School of Engineering, The University of Manchester, United Kingdom; 2: University of Sydney; 3: School of Health Sciences, The University of Manchester, United Kingdom

12:12pm - 12:24pm
ID: 389 / 1.1: 7

BIOMECHANICS OF HUMAN AORTA: SPATIAL AND DEMOGRAPHICAL VARIATIONS

A. Aggarwal, J.-E. Byun, A. McBride

University of Glasgow, United Kingdom

12:24pm - 12:36pm
ID: 180 / 1.1: 8

IN SILICO MODELING OF NEONATAL AORTIC ARCH HYPOPLASIA

T. Timmer^1,2, K. Jacob², G. Krings², M. Thirugnanasambandam¹, W. Huberts¹

1: Eindhoven University of Technology, Netherlands; 2: University Medical Center Utrecht, Netherlands

12:36pm - 12:39pm
ID: 643 / 1.1: 9

IMPACT OF WALL COMPLIANCE ON ABDOMINAL AORTIC ANEURYSM GEOMETRY-HAEMODYNAMIC RELATIONSHIP

S. Banagiri¹, V. Nandurdikar¹, T. Canchi², A. Revell¹, A. Frangi^1,3, A. B Harish¹

1: School of Engineering, The University of Manchester, United Kingdom; 2: University of Sydney; 3: School of Health Sciences, The University of Manchester, United Kingdom

12:39pm - 12:42pm
ID: 656 / 1.1: 10

TOWARDS A DIGITAL TWIN TO PREDICT PATIENT PROSTHESIS MISMATCH AFTER AORTIC VALVE REPLACEMENT

J. Jacob¹, J. McLaughlin¹, L. Hill², S. Bozkurt¹

1: School of Engineering, Ulster University, UK; 2: School of Nursing and Paramedic Science, Ulster University, UK

12:42pm - 12:45pm
ID: 334 / 1.1: 11

FLUID-STRUCTURE INTERACTION MODELING OF PATIENT-SPECIFIC STENOTIC CAROTID ARTERIES

M. B. Németh¹, Z. Mihály², G. Paál¹, B. Csippa¹

1: Budapest University of Technology and Economics, Hungary; 2: Semmelweis University, Department of Neurosurgery and Neurointerventions, Hungary

12:45pm - 12:48pm
ID: 446 / 1.1: 12

NON-INVASIVE PRESSURE-VOLUME LOOP IN PATIENTS WITH AORTIC STENOSIS

G. Palazzo¹, S. Di Filippo¹, G. Disabato¹, R. Gorla¹, P. Spagnolo¹, M. Lombardi¹, F. Bedogni¹, F. Sturla^1,2

1: IRCCS Policlinico San Donato, Italy; 2: Politecnico di Milano, Milano, Italy

12:48pm - 12:51pm
ID: 435 / 1.1: 13

FINITE-VOLUME IMMERSED-BOUNDARY MODELLING OF LEFT-HEART VALVE-FLOW MECHANICS FOR XENOTRANSPLANTATION

S. Pamulaparthi Venkata, C. Valeti, P. Cardiff

University College Dublin, Ireland

12:51pm - 12:54pm
ID: 150 / 1.1: 14

MRI-INFORMED HAEMODYNAMIC MODELLING FOR NONINVASIVELY QUANTIFYING CEREBROVASCULAR STIFFNESS

B. Ghitti¹, S. Dempsey², F. Argus¹, G. Maso Talou¹

1: Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand; 2: GE HealthCare, Gisborne, New Zealand

12:54pm - 12:57pm
ID: 618 / 1.1: 15

TOWARD CFD-BASED ESTIMATION OF PEAK-TO-PEAK GRADIENT IN AORTIC COARCTATION

M. A. Cetățoiu¹, B. M. Fanni², C. Bonfanti^1,2, S. Bonfanti^1,2, L. Ait Ali³, C. Marrone³, F. Berti¹, G. Pennati¹, S. Celi²

1: Laboratory of Biological Structures Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering Giulio Natta, Politecnico di Milano, Italy; 2: BioCardioLab, Bioengineering Unit, Fondazione Toscana Gabriele Monasterio, Ospedale del Cuore, Italy; 3: Pediatric Cardiology and Adult CHD Unit , Fondazione Toscana Gabriele Monasterio, Ospedale del Cuore, Italy

12:57pm - 1:00pm
ID: 687 / 1.1: 16

CALIBRATION OF A SPHERICAL VENTRICULAR MODEL FOR CARDIAC DIGITAL TWIN APPLICATIONS

F. Ninno, M. Pfaller

Yale University, Department of Biomedical Engineering, New Haven, CT, USA

11:00am - 11:12am
ID: 282 / 1.2: 1

RADIOMICS-BASED IDENTIFICATION OF PATIENTS WITH CARDIOVASCULAR DISEASES FROM RETINAL IMAGES

I. Bottini^1,2,3, A. Corti³, B. Grossi^1,2,4, L. M. Perri^1,4, R. Tatoni¹, M. R. Romano^1,2, G. Condorelli^1,2, V. D. Corino³, L. Mainardi³

1: Department of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy; 2: IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy; 3: Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy; 4: Department of Chemistry, Material and Chemical Engineering, Politecnico di Milano, Milan, Italy

11:12am - 11:24am
ID: 527 / 1.2: 2

DEFORMABLE IMAGE REGISTRATION ASSESSMENT OF THE AORTIC REMODELING IN AORTOPATHY PATIENTS

R. Sivera¹, S. Schievano¹, A. Impellizzeri³, G. L. Ragazzoni², E. Cervi², C. Capelli¹

1: Institute of Cardiovascular Science, University College London, United Kingdom; 2: Department of Cardiology, Great Ormond Street Hospital, United Kingdom; 3: Barts' Heart Centre, St Bartholomew's Hospital, United Kingdom

11:24am - 11:36am
ID: 267 / 1.2: 3

A SECTOR-BASED RADIOMIC APPROACH TO CHARACTERIZE CAROTID PLAQUE EVOLUTION

M. De Santis¹, A. Tziotziou², D. Bos², L. Mainardi¹, V. Corino^1,3, A. Akyildiz^2,4, A. Corti¹

1: Politecnico di Milano, Milan, Italy; 2: Erasmus Medical Center, Rotterdam, the Netherlands; 3: Centro Cardiologico Monzino IRCCS, Milan, Italy; 4: Delft University of Technology, the Netherlands

11:36am - 11:48am
ID: 428 / 1.2: 4

QUANTIFYING FEATURES OF UMBILICAL CORD VASCULAR PHENOTYPES FROM ULTRASOUND IMAGING

D. Hardman¹, K. Hunt², R. C. Townsend^1,3, M. O. Bernabeu¹, P. Hoskins⁴

1: Centre for Medical Informatics, Usher Institute, University of Edinburgh, UK; 2: Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, UK; 3: Institute for Regeneration and Repair, University of Edinburgh, UK; 4: Centre for Reproductive Health, Institute for Regeneration and Repair, University of Edinburgh, UK

11:48am - 12:00pm
ID: 227 / 1.2: 5

HCM-NET: A DEEP NEURAL NETWORK FOR IMPROVED CARDIAC IMAGE SEGMENTATION OF HYPERTROPHIC CARDIOMYOPATHY

E. McMillian¹, A. Banerjee², A. Bueno-Orovio¹

1: Department of Computer Science, University of Oxford, Oxford OX1 3QD, United Kingdom; 2: Institute of Biomedical Engineering, University of Oxford, Oxford OX3 7DQ, United Kingdom

12:00pm - 12:12pm
ID: 360 / 1.2: 6

SMARTLYF – A STRESS-INTEGRATED DIGITAL TWIN FRAMEWORK FOR FUNCTIONAL RISK STRATIFICATION IN AAA

H. von Tengg-Kobligk¹, N. L'Abate¹, G. M. Cereghetti¹, D. Becker², M. Thirugnanasambandam⁴, O. Opatz³, A. Aksöz⁵, B. Jung¹, F. Haupt¹

1: Insel Group, Inselspital, University of Bern, Dpt. of Diagnostic, Internventional and Pediatric Radiology, Bern, Switzerland; 2: Department of Vascular Surgery, Inselspital, University of Bern, Switzerland; 3: Department of Anesthesiology and Intensive Care Medicine, Charité – Universitätsmedizin Berlin, Germany; 4: PULS/e, Department of Biomedical Engineering, Eindhoven, the Netherlands; 5: Laboratory for Rehabilitation Engineering, Bern University of Applied Sciences, Switzerland

12:12pm - 12:24pm
ID: 623 / 1.2: 7

AUTOMATED VMS-CFD PIPELINE FOR HEMODYNAMIC DECISION SUPPORT IN ANEURYSM SEGMENTATION

J. Zarate¹, B. Figliuzzi¹, P. Meliga¹, Y. Chau², E. Hachem¹

1: Mines Paris - PSL; 2: Nice University Hospital

12:24pm - 12:36pm
ID: 370 / 1.2: 8

LEFT VENTRICULAR VORTEX DYNAMICS AS A MECHANISTIC BIOMARKER OF CARDIAC FUNCTION BASED ON CLINICAL CARDIAC DATA

P. Soni¹, A. bhattacharya¹, A. Y. Usmani², S. K. Viswakerma¹, S. K. Rai¹, O. Shankar³, A. Verma⁴, B V R. Kumar⁵

1: School of Biomedical Engineering, Indian Institute of Technology (BHU) Varanasi, India; 2: Deparment of Mechanical Engineering, Zakir Hussian College of Engineering and Technology AMU, Aligarh, India; 3: Department of Cardiology, Insititue of Medical Sciences Varanasi, India; 4: Department of Radio-diagnosis, Insititue of Medical Sciences Varanasi, India; 5: Department of Mathematics and Statistics, Indian Institute of Technology Kanpur, India

12:36pm - 12:39pm
ID: 459 / 1.2: 9

TOWARDS A PATIENT-STRUCTURED DATA MODEL FOR AI-DRIVEN ANALYSIS OF PHOTON-COUNTING CORONARY CT

A. Arcangeli, K. Capellini, A. Aimo, M. Emdin, M. Occhipinti, M. Muca, F. Pignatelli, C. De Gori, V. Positano, S. Celi, A. Clemente

Fondazione Gabriele Monasterio, Italy

12:39pm - 12:42pm
ID: 295 / 1.2: 10

RECONSTRUCTION OF PLANAR BLOOD FLOW IN LEFT VENTRICLE WITH OUT-OF-PLANE MASS TRANSPORT CONSIDERED

F. Yamada¹, K. Shimano², S. Shiratori², H. Nagano²

1: Graduate School of Integrative Science and Engineering, Tokyo City University, Japan; 2: Department of Mechanical Systems Engineering, Faculty of Science and Engineering, Tokyo City University, Japan

12:42pm - 12:45pm
ID: 205 / 1.2: 11

TOPOLOGICAL DEEP LEARNING ON GRAPHS FOR ARRHYTHMIA RISK PREDICTION FROM IMAGES

E. Njomgue Fotso^1,2, L. Buntheng², H. COCHET², M. Sermesant^1,2

1: Inria, Université Côte d'Azur, Epione team, Sophia Antipolis, France; 2: IHU Liryc, Université de Bordeaux, Bordeaux, France

12:45pm - 12:48pm
ID: 447 / 1.2: 12

AUTOMATED FRAMEWORK FOR CT-BASED STRAIN ESTIMATION AT THE LEFT ATRIAL APPENDAGE LANDING ZONE

I. Verdirame^1,2, A. Papini^1,2, F. Dell'Agnello¹, R. Buongiorno¹, B. M. Fanni¹, E. Vignali¹, S. Berti³, S. Celi¹

1: BioCardioLab, Bioengineering Unit, Fondazione Monasterio, Massa, Italy; 2: Department of Information Engineering, University of Pisa, Pisa, Italy; 3: Adult Cardiology Unit, Fondazione Monasterio, Massa, Italy

12:48pm - 12:51pm
ID: 660 / 1.2: 13

MATRIX-FREE SIMULATION OF CARDIAC PERFUSION ON HIGHPERFORMANCE COMPUTING ARCHITECTURES

J. Wang, L. Dede'

MOX, Dipartimento di Matematica Politecnico di Milano, Italy

12:51pm - 12:54pm
ID: 677 / 1.2: 14

UNCERTAINTY QUANTIFICATION IN CARDIAC MODEL PERSONALISATION FROM ULTRAFAST ULTRASOUND

C. Ferrario^1,2, M. Sermesant^1,2

1: Inria, France; 2: IHU Liryc, France

12:54pm - 12:57pm
ID: 680 / 1.2: 15

RESIDUAL GRAPH NEURAL NETWORK FOR VASCULAR RECONSTRUCTION FROM THINNING SKELETONS

V. Bedi

University College London, United Kingdom

12:57pm - 1:00pm
ID: 682 / 1.2: 16

A COMPUTATIONAL MODEL OF THE HEART TO INVESTIGATE RIGHT HEART FAILURE

G. Guerin¹, A. Banti¹, C. Dupont¹, E. Galli², A.-V. Salsac¹, E. Cutrì¹

1: Université de technologie de Compiègne, CNRS, Alliance Sorbonne Université, BMBI, Compiègne, France; 2: Translational Cardiovascular Medicine, Université de Strasbourg, France

11:00am - 11:12am
ID: 134 / 1.3: 1

IMAGE-BASED HIP FRACTURE ASSESSMENT WITH 3D CNN SURROGATES

Y. Zhou¹, D. Jha¹, A. D Praveen¹, S. J. Ferguson^1,2, T. Hoefler^1,2, B. Helgason^1,2

1: Singapore-ETH Centre, Singapore; 2: ETH-Zürich, Switzerland

11:12am - 11:24am
ID: 170 / 1.3: 2

AN FPCA-BASED METHOD TO PREDICT TIBIOFEMORAL KINEMATICS FROM TWO BIPLANE RADIOGRAPHS

E. Jolas¹, S. Guitteny¹, N. Fougeron², R. Aissaoui³, C. Pontonnier², R. Dumas¹

1: Univ. Eiffel, LBMC UMR_T9406, Lyon, France; 2: Univ. Rennes, Inria, CNRS, IRISA - UMR 6074, Rennes, France; 3: ÉTS, LIO-ETS, Montréal, Canada

11:24am - 11:36am
ID: 237 / 1.3: 3

A VOXEL-BASED LINEAR FINITE ELEMENT MODEL TO PREDICT PROXIMAL HIP FRACTURE IN SIDE-FALLS

J. Wilkinson, C. Brockett, P. Bhattacharya

Insigneo Institute and the University of Sheffield, United Kingdom

11:36am - 11:48am
ID: 252 / 1.3: 4

IN-SILICO INFORMED GAIT RETRAINING TO REDUCE MEDIAL COMPARTMENT LOADING IN EARLY KNEE OSTEOARTHRITIS: A PROOF-OF-CONCEPT STUDY

M. Willems, B. A. Killen, I. Jonkers

KU Leuven, Belgium

11:48am - 12:00pm
ID: 285 / 1.3: 5

SURFACE EMG-DRIVEN MODELING OF ANKLE BIOMECHANICS IN STAIR ASCENDING FOR PROSTHETIC DEVICE DEVELOPMENT

E. Bozdag^1,3, B. Imamoglu Yildirim¹, S. Öncü², C. A. Yücesoy¹

1: Institute of Biomedical Engineering, Boğaziçi University, Istanbul, Turkey; 2: Department of Mechanical Engineering, Boğaziçi University, Istanbul, Turkey; 3: Technical University of Munich, TUM School of Computation, Information and Technology, Munich, Germany

12:00pm - 12:12pm
ID: 407 / 1.3: 6

IMPACT OF PERSONALIZED GEOMETRY ON ESTIMATIONS OF OA-RELATED BIOMARKERS IN A MULTI-SCALE FRAMEWORK

A. Abedi¹, S. A. Elahi¹, Y. Zhang¹, A. Esrafilian², M. Willems¹, B. A. Killen¹, I. Jonkers¹

1: Department of Movement Sciences, KU Leuven, Leuven, Belgium; 2: Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

12:12pm - 12:24pm
ID: 436 / 1.3: 7

A LOCALIZED ARTICULAR CARTILAGE TEAR INDUCES GLOBAL BONE ADAPTATION: A FINITE ELEMENT STUDY

A. Paz Carvajal^1,2, M. Venäläinen³, J. Salo⁴, H. Isaksson⁵, R. Korhonen¹, P. Tanska¹, M. Liukkonen²

1: Department of Technical Physics, University of Eastern Finland, Finland; 2: Imaging Center, Kuopio University Hospital, Finland; 3: Department of Medical Physics, Turku University Hospital and University of Turku, Finland; 4: Orthopaedics and Traumatology Clinic, Mehiläinen, Helsinki, Finland; 5: Department of Biomedical Engineering, Lund University, Sweden

12:24pm - 12:36pm
ID: 548 / 1.3: 8

DEVELOPMENT OF AN EMG-INFORMED 6-DOF MUSCULOSKELETAL KNEE MODEL FOR INJURY PREVENTION

M. Dalle Vacche, G. Rigoni, S. Chiocca, F. Spolaor, Z. Sawacha

University of Padua, Italy

12:36pm - 12:39pm
ID: 194 / 1.3: 9

FRAMEWORK FOR ENDURANCE EVALUATION OF CUSTOM-MADE OSSEOINTEGRATED PROSTHESES FOR TRANSFEMORAL AMPUTEES

G. Galteri¹, C. Curreli², G. Dozza¹, M. Viceconti¹, L. Cristofolini¹

1: Department of Industrial Engineering, Alma Mater Studiorum-University of Bologna, Bologna, Italy; 2: Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

12:39pm - 12:42pm
ID: 211 / 1.3: 10

IMPLEMENTATION OF A MUSCULOSKELETAL PELVIC FLOOR MODEL AND SIMULATION OF PHYSIOLOGICAL SCENARIOS

T. Baumgartner¹, D. Ignasiak², B. Röhrnbauer¹

1: Institute of Mechanical Systems, School of Engineering, Zurich University of Applied Sciences/ZHAW, Switzerland; 2: Institute for Biomechanics, ETH Zurich, Switzerland

12:42pm - 12:45pm
ID: 288 / 1.3: 11

AI-POWERED DIGITAL TWIN PIPELINE FOR SKELETAL MUSCLE USING UNIFIED CNN-MLP-PINN FRAMEWORK

N. Mehrabi¹, G. Handsfield²

1: University of North Carolina at Chapel Hill, United States of America; 2: UNC-Chapel Hill & NC State University, United States of America

12:45pm - 12:48pm
ID: 547 / 1.3: 12

STATISTICAL SHAPE MODELING FOR DISTAL HUMERUS RECONSTRUCTION FROM ROUTINE CLINICAL CT SCANS

L. McCarthy¹, J. Hereš², S. J. Ferguson¹, P. Moroder³, A. Porto⁴, E. C. Herbst^1,3

1: Institute for Biomechanics, ETH, Zurich, Switzerland; 2: University of West Bohemia, Czech Republik; 3: Schulthess Klinik, Zurich, Switzerland; 4: University of Florida, U.S.A.

12:48pm - 12:51pm
ID: 344 / 1.3: 13

EX VIVO EXPERIMENTAL INVESTIGATIONS AND MODELLING OF VISCO-HYPERELASTIC BEHAVIOUR OF THE HUMAN FACIAL TISSUES

E. Awad^1,2, N. Briot¹, M. Hossain¹, G. Chagnon¹, D. Peric¹

1: Grenoble Alpes University, France; 2: Swansea University

12:51pm - 12:54pm
ID: 397 / 1.3: 14

ENHANCING FALL RISK EVALUATION: A FRAMEWORK BASED ON DIGITAL HEALTH TOOLS

P. Riccioni¹, R. Fognani¹, G. M. Farella², L. Berti², A. Leardini³, G. Martinese⁴, M. Miceli⁴, S. Ranciati⁵, F. Lamberti⁵, M. Baleani¹, G. Davico⁶

1: Laboratorio di Tecnologia Medica, IRCCS Istituto Ortopedico Rizzoli, Italy; 2: Medicina Fisica e Riabilitativa1, IRCCS Istituto Ortopedico Rizzoli, Italy; 3: Laboratorio Analisi del Movimento e Valutazione Funzionale Protesi, IRCCS Istituto Ortopedico Rizzoli; 4: Radiologia Diagnostica e Interventistica, IRCCS Istituto Ortopedico Rizzoli, Italy; 5: Dipartimento di Scienze Statistiche, Università di Bologna, Italy; 6: Dipartimento di Ingegneria Industriale, Università di Bologna, Italy

12:54pm - 12:57pm
ID: 670 / 1.3: 15

THE IMPACT OF GAIT SPEED ON THE PREDICTED KNEE LOADS DURING LEVEL WALKING

G. Davico

Alma Mater Studiorum - University of Bologna, Italy

12:57pm - 1:00pm
ID: 678 / 1.3: 16

FACET JOINTS COMPUTATIONAL MODELLING: DO LITERATURE-DERIVED CONTACT PARAMETERS COMPROMISE FIDELITY?

R. Bishr, S. Bhattacharya, M. Mengoni

Institute of Medical and Biological Engineering, University of Leeds, Leeds LS2 9JT, United Kingdom

11:00am - 11:12am
ID: 357 / 1.4: 1

MODEL-INFORMED RADIOTHERAPY SCHEDULE SELECTION UNDER HYPOXIA: A PHENOTYPE-STRUCTURED PDE APPROACH

F. Albanese^1,3, G. Chiari², M. Delitala¹

1: Politecnico di Torino, Italy; 2: Basque Center for Applied Mathematics, Spain; 3: Swinburne University of Technology, Australia

11:12am - 11:24am
ID: 631 / 1.4: 2

DISCRETE-CONTINUOUS MODELLING AND CALIBRATION OF CANCER SPHEROID FORMATION

E. C. Braun¹, G. Bretti¹, M. Menci², M. Semplice³, S. Preda³

1: Istituto per le Applicazioni del Calcolo ”Mauro Picone (IAC-CNR), Roma , Italy; 2: Università Campus Bio-Medico di Roma, Italy; 3: Dipartimento di Scienza e Alta Tecnologia, Università dell’Insubria, Italy

11:24am - 11:36am
ID: 401 / 1.4: 3

COMPUTATIONAL MODEL OF HIGH GRADE SEROUS OVARIAN CANCER CLONAL EVOLUTION

M. Cortesi, E. D. Giordano

University of Bologna, Italy

11:36am - 11:48am
ID: 497 / 1.4: 4

MECHANISTIC MODELING OF INFUSION TIME-OF-DAY EFFECT ON IMMUNE CHECKPOINT INHIBITOR ANTITUMOUR EFFICACY

M. Haghebaert¹, S. Dulong^1,2, P. Innominato³, F. Lévi², B. Duchemann², A. Ballesta¹

1: Inserm U1331, Institut Curie, Mines-Paris, PSL Univ., France; 2: Cancer Chronotherapy unit, INSERM, Univ Paris Saclay, France.; 3: Ysbyty Gwynedd Hospital, Warwick University, UK

11:48am - 12:00pm
ID: 308 / 1.4: 5

PREDICTING RADIOTHERAPY OUTCOMES: A MULTI-SCALE IN SILICO FRAMEWORK COUPLING VASCULAR OXYGEN DYNAMICS WITH TUMOUR PHENOTYPIC EVOLUTION

C. Macaluso¹, P. Vitullo¹, S. Gazzoni¹, L. Possenti², T. Rancati², P. Zunino¹

1: MOX, Department of Mathematics, Politecnico di Milano, Milan, Italy; 2: CMON Lab, Data Science Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

12:00pm - 12:12pm
ID: 359 / 1.4: 6

IN SILICO MODELING OF BONE METASTASIS FOR TUMOR PROGRESSION AND THERAPY RESPONSE

L. Marsilio^1,2, S. Barrios³, S. Maksimovic³, A. Maccarini^2,4, E. Serafini^2,5,6, M. Grimaldi^1,2, T. J. Heyman³, P. Cerveri^1,4, S. Casarin^2,5,6, E. Dondossola³

1: Politecnico di Milano, Italy; 2: Houston Methodist Research Institute, Houston, Texas; 3: The University of Texas MD Anderson Cancer Center; 4: Univerità degli Studi di Pavia, Italy; 5: La Rochelle Université, La Rochelle, France; 6: Houston Methodist Hospital, Houston, Texas

12:12pm - 12:24pm
ID: 622 / 1.4: 7

A PHYSICALLY CONSISTENT MODEL OF EXPANSILE TUMOR GROWTH

J. Stollberg, M. F. ten Eikelder, D. Schillinger

Technical University of Darmstadt, Germany

12:24pm - 12:36pm
ID: 251 / 1.4: 8

MULTISCALE RADIATION–MATTER INTERACTION SIMULATIONS IN 3D MULTICELLULAR IN SILICO TUMOR SUBSTRATES

C. Tinelli, C. Scotti, L. Morelli, G. Baroni, C. Paganelli

Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy

12:36pm - 12:48pm
ID: 569 / 1.4: 9

MACHINE LEARNING AND NETWORK MODELING REVEAL IMMUNE REGULATION IN BREAST CANCER AXILLARY METASTASIS

A. Fischer-Carles^1,4, G. Piella⁴, C. López^1,3, T. Sánchez-Alcántara¹, N. Gallardo-Borràs¹, E. Sauras-Colón¹, A. Fiorin^1,3, M. Lejeune^1,3, R. Bosch Príncep¹, L. Adalid-Llansa^1,2, D. Mata Cano¹, J. Noailly⁴

1: Oncological Pathology and Bioinformatics Research Group, HUTVC, IRB CatSud, URV, Spain; 2: Department of Pathology, HUJ23, ICS, Spain; 3: Department of Computer Engineering and Mathematics, URV, Spain; 4: BCN MedTech, Department of Engineering, UPF, Spain

12:48pm - 12:51pm
ID: 221 / 1.4: 10

IN SILICO PSYCHO-ONCOLOGY: AI MODELS FOR PREDICTING QUALITY OF LIFE & IDENTIFYING PREDICTORS IN WOMEN WITH EARLY BREAST CANCER

E. Kolokotroni¹, P. Poikonen-Saksela², G. Stamatakos¹

1: National Technical University of Athens, School of Electrical and Computer Engineering, Institute of Communication and Computer Systems, Athens, Greece; 2: University of Helsinki, Faculty of Medicine, HUS Comprehensive Cancer Center, Helsinki, Finland

12:51pm - 12:54pm
ID: 301 / 1.4: 11

MECHANISTIC MODELING OF RADIOTHERAPY‑INDUCED ABSCOPAL RESPONSES IN SOLID TUMORS

A. G. Hadjigeorgiou¹, Y. Roussakis², C. Zamboglou^2,3,4, T. Stylianopoulos¹

1: University of Cyprus, Cyprus; 2: German Oncology Center, Cyprus; 3: University of Freiburg Medical Center, Germany; 4: German Cancer Consortium, Germany

12:54pm - 12:57pm
ID: 467 / 1.4: 12

A GOMPERTZ-TYPE MODEL FOR SERUM PROSTATE-SPECIFIC ANTIGEN KINETICS IN PATIENTS IN ACTIVE SURVEILLANCE

B. Dionisi Ferrera, F. Badenchini, C. Marenghi, A. Cicchetti, T. Rancati, J. Iacovacci

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

12:57pm - 1:00pm
ID: 628 / 1.4: 13

A MULTISCALE MODEL OF GLIOBLASTOMA-MESENCHYMAL STROMAL CELLS TUMOR SPHEROIDS

A. Prasilova, B. Charvatova, T. Bily

Charles University, Czech Republic

11:00am - 11:12am
ID: 395 / 1.5: 1

FROM CLASSICAL ML TO GNNS: ACCELERATING BONE STRESS PREDICTION FROM HOURS TO MILLISECONDS

S. Okkath Krishnanunni¹, A. Moslemivaraki¹, E. Alizadeh¹, M. A González Ballester^1,2, J. Noailly¹

1: University of Pompeu Fabra (UPF), Spain; 2: ICREA, Spain

11:12am - 11:24am
ID: 400 / 1.5: 2

PATIENT-SPECIFIC 3D RENAL PERFUSION MODELS IN SUPPORT OF SELECTIVE CLAMPING DURING PARTIAL NEPHRECTOMY

S. Vermijs^1,2,3, J. Vangeneugden^2,3,4, K. Mestdagh^2,3,4, P. De Visschere⁵, P. De Backer^6,7, P. De Kuyper⁸, F. Baekelandt⁹, C. Ghysel⁹, Y. Raskin¹⁰, B. Bynens¹⁰, C. Berquin⁴, N. Lumen^2,4, K. Decaestecker^2,4,8, C. Van Praet^2,3,4, C. Debbaut^1,3

1: BioMMedA@iBME, Dept. of Electronics and Information Systems, Faculty of Engineering and Architecture, Ghent University, Belgium; 2: Dept. of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University, Belgium; 3: Cancer Research Institute Ghent, Belgium; 4: Dept. of Urology, ERN eUROGEN accredited center, Ghent University Hospital, Belgium; 5: Dept. of Radiology and Nuclear Medicine, Ghent University, Belgium; 6: ORSI Academy, Belgium; 7: Dept. of Urology, AZORG, Belgium; 8: Dept. of Urology, AZ Maria Middelares Hospital, Belgium; 9: Dept. of Urology, AZ Sint-Jan Brugge, Belgium; 10: Dept. of Urology, Ziekenhuis Oost-Limburg (ZOL) Genk, Belgium

11:24am - 11:36am
ID: 452 / 1.5: 3

CIN-VIT@LLY: A REUSABLE CONCEPT FOR VIRTUAL TWINS INCUBATED WITHIN HOSPITAL INFRASTRUCTURE

E. Kutafina¹, A. Maxion², J. Tigerholm², J. Wodke³, M. Trommer¹, O. Beyan¹

1: University Hospital Cologne, Germany; 2: University Hospital RWTH Aachen; 3: University Hospital Greifswald

11:36am - 11:48am
ID: 486 / 1.5: 4

FROM DATA TO DIAGNOSIS: A HOSPITAL PROOF OF CONCEPT OF AI-DRIVEN ALLERGY DIAGNOSTICS

P. Tworek¹, M. Szczypka¹, M. Mikołajczyk², R. Lewandowski^2,3, J. Sousa^1,4

1: Sano - Centre for Computational Personalized Medicine, Poland; 2: Voivodeship Rehabilitation Hospital for Children in Ameryka, Poland; 3: University of Warmia and Mazury, Poland; 4: Coimbra University, Multidisciplinary Institute of Ageing, Portugal

11:48am - 12:00pm
ID: 496 / 1.5: 5

ORTHOAI A NEUROSYMBOLIC FRAMEWORK FOR EVIDENCE-GROUNDED BIOMECHANICAL REASONING IN CLEAR ALIGNER ORTHODONTICS

E. Lansiaux^1,2, M. Leman¹, M. Ammi²

1: Lille University Hospital, France; 2: LIASD, Paris 8 University, France

12:00pm - 12:12pm
ID: 507 / 1.5: 6

ORTHOAI V2 FROM SINGLE-AGENT SEGMENTATION TO DUAL-AGENT TREATMENT PLANNING FOR CLEAR ALIGNERS

E. Lansiaux, M. Leman

STaR-AI, Emergency Department, Lille University Hospital, France

12:12pm - 12:24pm
ID: 597 / 1.5: 7

CLINICAL EVALUATION OF A GLUCOSE–INSULIN MODEL FOR INTENSIVE CARE UNIT PATIENTS WITHOUT EXOGENOUS INSULIN

P. Verstraeten¹, V. Uyttendaele¹, M. Seret¹, A.-F. Rousseau², B. Lambermont², G. Minguet², D. Wertz², N. Esser³, J. G. Chase⁴, T. Desaive¹

1: Model-based therapeutics, GIGA Institute, University of Liège, Belgium; 2: Department of Intensive Care, CHU Liège, Belgium; 3: Departmentof Diabetology, CHU Liège, Belgium; 4: Department of Mechanical Engineering, University of Christchurch, New Zealand

12:24pm - 12:36pm
ID: 603 / 1.5: 8

AI-CARE: A DECISION SUPPORT SYSTEM BASED ON FEDERATED AND CONTINUOUS LEARNING

D. Tartarini^1,2, M. mittal¹, L. Thomas¹, V. Venkatakrishnan¹, J. Walton¹

1: University of Sheffield, United Kingdom; 2: Insigneo Institute for in silico medicine, Sheffield, UK

12:36pm - 12:39pm
ID: 120 / 1.5: 9

MODULAR PLUGIN TO RADIOTHERAPY TREATMENT-PLANNING SYSTEM EMPOWERS EVIDENCE-BASED TREATMENT PLANNING

H. Hållberg^1,2, E. Dalqvist^1,3, A. Berglund², E. Onjukka^1,3

1: Department of Nuclear Medicine and Medical Physics, Karolinska University Hospital, Stockholm, Sweden; 2: Epistat AB, Uppsala, Sweden; 3: Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden

12:39pm - 12:42pm
ID: 645 / 1.5: 10

VIBRONAV: VIBROACOUSTIC SIGNAL ANALYSIS FOR AI-ASSISTED NAVIGATION IN MINIMALLY INVASIVE PROCEDURES

J. Gawron¹, A. Kos¹, H. Oran², S. Rybak¹, D. Rzepka², K. Steeg³, M. Friebe¹, K. Heryan^1,2

1: AGH University of Krakow, Poland; 2: MedSun Labs sp. z o. o., Warsaw, Poland; 3: Justus‑Liebig‑University Giessen, Germany

12:42pm - 12:45pm
ID: 333 / 1.5: 11

DEEP MULTI-STATE MODELS FOR INDIVIDUALIZED PROGNOSIS IN MULTIPLE MYELOMA

S. Schwick¹, Y. Salimi¹, G. Azarias³, H. Fröhlich^1,2,4

1: Department of Biomedical AI & Data Science, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Sankt Augustin, Germany; 2: Bonn-Aachen International Center for Information Technology (b-it), University of Bonn, Bonn, Germany; 3: TriNetX Oncology GmbH, Freiburg, Germany; 4: Institute for Digital Medicine, University Hospital Bonn, Bonn, Germany

12:45pm - 12:48pm
ID: 182 / 1.5: 12

A REAL-TIME SIMULATION ENVIRONMENT FOR TAILORED BARIATRIC SURGERY

I. Toniolo^1,2, E. L. Carniel^1,2, G. Mazzucco^2,3

1: Department of Industrial Engineering, University of Padova, Italy; 2: Centre for Mechanics of Biological Materials, University of Padova, Italy; 3: Department of Civil, Environmental and Architectural Engineering, University of Padova, Italy

12:48pm - 12:51pm
ID: 311 / 1.5: 13

DATA-DRIVEN MODELLING OF EARLY KIDNEY GRAFT DYSFUNCTION CHALLENGES INJURY-CENTRIC PARADIGMS

A. I. Morales^1,2, M. Prieto^1,2, A. G. Casanova^1,2, Ó. Pellicer³, J. Tascón¹, A. Düwel¹, G. Tabernero¹, M. A. Ramos⁴, C. Gómez-Alamillo⁴, A. Coca⁵, J. D. Martín-Guerrero³, F. J. López-Hernández^1,2

1: Instituto de Investigación Biomédica de Salamanca, Spain; 2: Universidad de Salamanca, Spain; 3: Universitat de Valencia, Spain; 4: Hospital Valdecilla, Spain; 5: Hospital de Valladolid, Spain

12:51pm - 12:54pm
ID: 664 / 1.5: 14

TOXIPRED: A WEB-BASED EXPLAINABLE AI PLATFORM FOR MULTI-ENDPOINT DERMATOXICITY PREDICTION

M. Soltesova Prnova^1,2, A. Rybar², E. Rogansky², S. Račák², A. Pylypenko², D. Sira², M. Lepacek¹, P. Bodo¹, L. Soltes², M. Ries²

1: Center of Experimental Medicine Slovak Academy of Science, Slovak Republic; 2: Faculty of Informatics and Information Technologies, Slovak University of Technology in Bratislava, Slovakia

12:54pm - 12:57pm
ID: 672 / 1.5: 15

COMPREHENSIVE HEMODYNAMIC PROFILING OF VAD: A MCL STUDY UNDER DYNAMIC HEART FAILURE CONDITIONS

E. Vignali¹, E. Gasparotti¹, M. Hirschhorn², L. Fresiello³, S. Celi¹, B. M. Fanni¹

1: BioCardioLab, Bioengineering unit, Fondazione Toscana Gabriele Monasterio, Italy; 2: U.S. Food & Drug Administration, USA; 3: Cardiovascular and Respiratory Physiology, University of Twente, The Netherlands

11:00am - 11:12am
ID: 510 / 1.6: 1

FROM HOMEOSTASIS TO SYNOVITIS: A REGULATORY NETWORK MODEL OF MACROPHAGE POLARIZATION IN KNEE OSTEOARTHRITIS.

Y. ALEMU¹, Z. WORKINEH¹, L. TIO², J. MONFORT², J. NOAILLY¹

1: Universitat Pompeu Fabra, Spain; 2: Hospital del Mar Research Institute, Spain

11:12am - 11:24am
ID: 271 / 1.6: 2

DESIGN OF A FAST METAMODEL FOR THE GENERATION OF HD-SEMG AMPLITUDE HEATMAPS

M. Boubred, J. Laforet, S. Boudaoud

Université de Technologie de Compiègne, CNRS, BMBI, Compiègne, France.

11:24am - 11:36am
ID: 605 / 1.6: 3

INVESTIGATING THE DETECTION LIMITS FOR EMG-BASED CLASSIFICATION OF SPONTANEOUS MUSCLE ACTIVITY

P. Brandenburg¹, J. Marquetand², O. Röhrle¹, B. Senay², T. Klotz¹

1: Institute for Modeling and Simulation of Biomechanical Systems, University of Stuttgart, Germany, Germany; 2: Hertie-Institute for Clinical Brain Research, University of Tübingen, Germany

11:36am - 11:48am
ID: 540 / 1.6: 4

AN IN-SILICO FRAMEWORK TO SIMULATE TRAINING-DRIVEN MULTISCALE SKELETAL MUSCLE ADAPTATION

E. Feola, M. Sartori, N. Verdonschot

university of twente, Netherlands, The

11:48am - 12:00pm
ID: 432 / 1.6: 5

TOWARD DIGITAL TWINS OF OSTEOARTHRITIS: INTEGRATING GENETIC VARIANTS AND MECHANICAL SIGNALS

A. Gaikwad, J. Igras, J. Post

Quantitative Biology Lab, Department of BioEngineering Technologies, University of Twente,The Netherlands

12:00pm - 12:12pm
ID: 511 / 1.6: 6

ESTIMATING EYE-HEAD-NECK MUSCLE ACTIVATIONS FOR TARGET SKULL POSITIONING

T. Saigre, E. Harsigny, P. Alvarez, M. Duprez, S. Cotin

Université de Strasbourg, CNRS, Inria, ICube, F-67000 Strasbourg, France

12:12pm - 12:24pm
ID: 191 / 1.6: 7

KNEE JOINT VIRTUAL TWIN TO ESTIMATE MECHANO-INFLAMMATORY RESPONSE OF CARTILAGE

A. Salo¹, J. Kosonen¹, J. Peitola¹, A. Esrafilian¹, P. Tanska^1,2, R. Korhonen¹, A. Eskelinen^1,2

1: University of Eastern Finland, Kuopio, Finland; 2: Kuopio University Hospital, Wellbeing Services County of North Savo, Kuopio, Finland

12:24pm - 12:36pm
ID: 233 / 1.6: 8

IMPACT OF ANISOTROPIC MUSCLE CONDUCTIVITY ON PHRENIC NERVE ACTIVATION THRESHOLDS

L. Wegert¹, M. Ziolkowski¹, A. Hunold^1,2, T. Kalla¹, I. Lange¹, J. Haueisen¹

1: Technische Universität Ilmenau, Germany; 2: neuroConn GmbH, Germany

12:36pm - 12:39pm
ID: 456 / 1.6: 9

CHARACTERIZATION OF PCL SCAFFOLD MECHANICS AND THEIR SUITABILITY FOR TENDON CELL CULTURES

A. Pérez-Ruiz¹, M. Corral-Barricarte², E. Ruiz Robles¹, J. Grasa^2,3, S. Sanegre¹, J. Iamsamang⁴, M. Castilho⁴, B. Calvo^2,3

1: Department of Biomedical Sciences, School of Health Sciences, Universidad CEU Cardenal Herrera, Valencia, Spain; 2: Aragón Institute of Engineering Research (I3A), Universidad de Zaragoza, Spain; 3: Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain; 4: Biomaterial Engineering & Biofabrication, Departament of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

12:39pm - 12:42pm
ID: 146 / 1.6: 10

MULTISCALE MODELING OF ARTICULAR CARTILAGE COLLAGEN MATRIX: MECHANICAL IMPACT OF STRUCTURAL CHANGES

E. Núñez-Ortega¹, J. A. Sanz-Herrera¹, E. A. Gaffney², C. P. Brown³, E. Reina-Romo¹

1: University of Seville, Spain; 2: University of Oxford; 3: Queensland University of Technology

12:42pm - 12:45pm
ID: 544 / 1.6: 11

A COUPLED SIGNALING–METABOLIC MODEL OF CHONDROCYTE STATES IN OSTEOARTHRITIS

P. Tejero¹, L. Geris^1,2,3

1: Biomechanics Section, KU Leuven, Belgium; 2: Skeletal Biology & Engineering Research Center, KU Leuven, Belgium; 3: GIGA Research Center, U.Liège, Belgium

12:45pm - 12:48pm
ID: 606 / 1.6: 12

RULE-BASED PARTICLE SWARM OPTIMIZATION FOR PATIENT-SPECIFIC LUMPED PARAMERER CARDIOVASCULAR MODEL

F. Xu¹, E. Perra², M. Broomé³, S. Dual¹

1: Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, Sweden; 2: Getinge, Sweden; 3: Department of Physiology and Pharmacolog, Karolinska Institute, Sweden

12:48pm - 12:51pm
ID: 665 / 1.6: 13

AN IN SILICO FRAMEWORK FOR SPINAL CAGE DESIGN: MULTI-SCALE MODELLING OF AGENT BASED OSTEOINTEGRATION

A. Orlandini¹, C. Carrara², S. Baraldo¹, L. Gambardella³, A. Valente¹

1: SUPSI, Switzerland; 2: MCH-tronics Sagl; 3: USI, Switzerland

12:51pm - 12:54pm
ID: 671 / 1.6: 14

MULTISCALE IN SILICO MODELING OF CRANIOFACIAL DEFECT HEALING: FROM MECHANISMS TO VALIDATION

L. Lafuente-Gracia¹, L. Groeneveldt¹, M. Barzegari², C. Geeroms¹, A. Carlier³, L. Geris^1,4

1: KU Leuven, Belgium; 2: TU Eindhoven, The Netherlands; 3: Maastricht University, The Netherlands; 4: University of Liège, Belgium

12:54pm - 12:57pm
ID: 679 / 1.6: 15

KNEE OSTEOARTHRITIS MULTISCALE MODELING: INSIGHT TOWARD POPULATION LEVEL

M. A. Asadi Amoli^1,2, S. Mukherjee³, L. Geris^1,2

1: KU Leuven, Belgium; 2: University of Liège, Belgium; 3: Washington University at Saint Louis, USA

11:00am - 11:12am
ID: 162 / 1.7: 1

IN-SILICO TRIALS FOR RENAL ANEMIA TREATMENT USING DIGITAL TWINS OF DIALYSIS PATIENTS

D. J. Jörg, D. H. Fuertinger

Renal Research Institute, New York, United States

11:12am - 11:24am
ID: 172 / 1.7: 2

DIGITAL TWIN FRAMEWORK FOR PERSONALIZED ASSESSMENT OF HIP FRACTURE RISK REDUCTION STRATEGIES

D. Jha¹, A. Fung², Y. Zhou¹, A. D. Praveen¹, E. Schileo³, S. J. Ferguson^1,2, F. Taddei³, B. Helgason^1,2

1: ETH Singapore SEC Ltd, Singapore; 2: ETH-Zürich, Switzerland; 3: Istituto Ortopedico Rizzoli, Bologna, Italy

11:24am - 11:36am
ID: 186 / 1.7: 3

FRAILTY-AWARE IN SILICO TRIALS TO IMPROVE HIP FRACTURE INCIDENCE PREDICTION ACROSS COHORTS

G. Savelli¹, A. Aldieri², M. Viceconti²

1: Rizzoli Orthopaedic Institute, Italy; 2: University of Bologna, Italy

11:36am - 11:48am
ID: 238 / 1.7: 4

IN SILICO STUDY OF POST-INTERVENTIONAL RECONSTRUCTION STRATEGIES FOR INTRACRANIAL WIDE-NECK ANEURYSMS

A. Bernovskis^1,2, F. Gießler³, F. Gaidzik^1,4, N. Larsen⁵, S. Saalfeld⁴, P. Berg^1,2

1: Research Campus STIMULATE, OVGU, Germany; 2: Department of Medical Engineering, OVGU, Germany; 3: Institute for Medical Informatics and Statistics, UKSH, Germany; 4: Laboratory of Fluid Dynamics and Technical Flows, OVGU, Germany; 5: Department for Radiology and Neuroradiology, UKSH, Germany

11:48am - 12:00pm
ID: 343 / 1.7: 5

IN SILICO EVALUATION OF PATIENT DAILY ACTIVITIES ON KNEE IMPLANT WEAR USING IN VIVO DATA

D. Barbieri¹, L. Mattei², M. Viceconti³, C. Curreli¹

1: Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; 2: Department of Civil and Industrial Engineering, University of Pisa, Italy; 3: Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Italy

12:00pm - 12:12pm
ID: 388 / 1.7: 6

DEVELOPING A KNOWLEDGE INTEGRATION FRAMEWORK TO SUPPORT VIRTUAL PATIENT GENERATION FOR RARE DISEASES

G. Monchietto¹, S. Zohar¹, K. Sinclair²

1: INSERM, Inria, Université Paris-Cité, France; 2: Novartis Pharma AG, Switzerland

12:12pm - 12:24pm
ID: 410 / 1.7: 7

PATIENT-SPECIFIC SURGICAL PLANNING OF FEMORAL FRACTURES USING DIGITAL TWINS AND MACHINE LEARNING

O. L. Lorente¹, J. Gómez³, A. Bono², B. Martín del brio², J. Albareda³, S. Puértolas¹

1: Dept. Mechanical Engineering, University of Zaragoza, I3A Institute, Spain.; 2: Dept. of Electronic Engineering and Communications, University of Zaragoza, I3A Institute, Spain.; 3: Orthopedic Surgery and Traumatology, University Hospital Lozano Blesa, Zaragoza, Spain.

12:24pm - 12:36pm
ID: 177 / 1.7: 8

BREAKING THE SCALABILITY BARRIER: CLOUD-PARALLELIZED INFRASTRUCTURE FOR HIGH-THROUGHPUT IN SILICO CLINICAL TRIALS

C. Mueri¹, D. Pandurangan², G. Ramswami², S. Sovani³, S. Levine⁴, T. Marchal⁵, P. Favre¹

1: Zimmer Biomet, Switzerland; 2: Invisibl Cloud, India; 3: Amazon Web Services (AWS), USA; 4: Dassault Systèmes, USA; 5: Synopsys, Belgium

12:36pm - 12:39pm
ID: 239 / 1.7: 9

AI-DRIVEN DECISION SUPPORT SYSTEM TO EMPOWER ENGAGEMENT IN PEDIATRIC NEUROMOTOR REHABILITATION

S. Costantini^1,2, F. A. Storm², E. Biffi², G. Andreoni^2,3, A. M. Bianchi¹

1: Department of Electronics Information and Bioengineering, Politecnico di Milano, Milan, Italy; 2: Scientific Institute, IRCCS “E. Medea”, Bosisio Parini, Italy; 3: Department of Design, Politecnico di Milano, Milan, Italy

12:39pm - 12:42pm
ID: 119 / 1.7: 10

COMPARISON OF BIOMECHANICAL STABILITY OF ANKLE ARTHRODESIS TECHNIQUES USING FINITE ELEMENT ANALYSIS

A. Tanaka, K. Noriyuki, T. Yamamoto, T. Takami, R. Okada, S. Yoshida, M. Kamachi, S. Sano, R. Kuroda

Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Japan

12:42pm - 12:45pm
ID: 279 / 1.7: 11

ANGULATED SCREW CONFIGURATION REDUCES IMPLANT STRESS IN SUBTALAR ARTHRODESIS: A FINITE ELEMENT STUDY

T. Yamamoto, A. Tanaka, N. Kanzaki, T. Takami, R. Okada, S. Yoshida, M. Kamachi, S. Sano, R. Kuroda

Kobe University Graduate School of Medicine, Japan

12:45pm - 12:48pm
ID: 674 / 1.7: 12

FAST HIGH-FIDELITY NEURAL NETWORK SURROGATE FOR INFERENCE OF A CARDIOVASCULAR-BAROREFLEX MODEL

A. Ben-Tolila¹, X. Chen², J. Duprez¹, A. Al Wazzan¹, E. Donal¹, A. Hernández¹, F. Agakov², V. Le Rolle¹

1: University of Rennes, CHU Rennes, Inserm, LTSI - U1099, Rennes, France; 2: Pharmatics Ltd., Edinburgh, United Kingdom

12:48pm - 12:51pm
ID: 663 / 1.7: 13

AUTOMATED FINITE ELEMENT MODELS OF VERTEBRAE FOR PATIENT-SPECIFIC BONE FRAGILITY ASSESSMENT

G. Fraterrigo¹, E. Schileo¹, F. Taddei¹, L. Grassi²

1: Istituto Ortopedico Rizzoli, Italy; 2: Lund University, Sweden

2:30pm - 2:42pm
ID: 533 / 2.1: 1

DESIGN OPTIMISATION OF DIALYSIS CATHETERS FOR PAEDIATRIC PATIENTS USING A COMPUTATIONAL APPROACH

C. Bruno¹, A. Klostermann², J. Oldenburg², F. Borowski², M. Stiehm², S. Schievano¹, R. Shroff³, C. Capelli¹

1: University College London, London, UK; 2: Institute for ImplantTechnology and Biomaterials e.V., Rostock, Germany; 3: Great Ormond Street Hospital for Children, London, UK

2:42pm - 2:54pm
ID: 110 / 2.1: 2

STRUCTURAL DESIGN AND OPTIMIZATION OF BIODEGRADABLE ZINC ALLOY VASCULAR STENTS BASED ON MACHINE LEARNING

Z. Lin, G. Yuan

Shanghai Jiao Tong University, China, People's Republic of

2:54pm - 3:06pm
ID: 313 / 2.1: 3

MODELLING STENT-INDUCED REMODELLING IN ANEURYSMAL AORTAS USING HOMOGENISED CONSTRAINED MIXTURE THEORY

S. K. Marimuthu¹, C. Maclean³, R. Brodie³, N. A Hill², S. McGinty¹

1: James Watt School of Engineering, University of Glasgow, Glasgow, UK; 2: School of Mathematics and Statistics, University of Glasgow, Glasgow, UK; 3: R&D, TerumoAortic, Glasgow, UK

3:06pm - 3:18pm
ID: 440 / 2.1: 4

IN-SILICO ASSESSMENT OF CONTACT FORCE EFFECTS IN CARDIAC CATHETER ABLATION

A. Petras¹, L. Pasini¹, M. Anees¹, Z. Moreno Weidmann², D. Vilades Medel², A. Neic³, E. J. Vigmond^4,5, J. M. Guerra², L. Gerardo-Giorda⁶

1: RICAM - Johann Radon Institute for Computational and Applied Mathematics, Austria; 2: Hospital de la Santa Creu i Sant Pau, IR SANT PAU, Universitat Autonoma de Barcelona, CIBERCV, Spain; 3: NumeriCor GmbH, Austria; 4: Liryc Heart Rhythm Disease Institute, Fondation Bordeaux University, France; 5: CNRS, Bordeaux INP, IMB, University of Bordeaux, France; 6: Johannes Kepler University (JKU), Austria

3:18pm - 3:30pm
ID: 414 / 2.1: 5

DEPTH-DEPENDENT CORONARY CLEARANCE AFTER TAVI: A PATIENT-SPECIFIC IN SILICO STUDY

S. U. Zoni¹, L. R. Mata Quinonez², S. Bhat², L. P. Dasi², S. Singh-Gryzbon¹

1: Department of Chemical Engineering & Biotechnology, University of Cambridge, Cambridge, UK; 2: Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA

3:30pm - 3:42pm
ID: 586 / 2.1: 6

HIGH FIDELITY INTRASACCULAR FLOW DISRUPTOR MODELLING FOR INTRACRANIAL ANEURYSM TREATMENT

C. Faitini¹, P. Meliga¹, Y. Chau², E. Hachem¹

1: Mines Paris - PSL University; 2: Interventional Neuroradiology Department, Nice University Hospital

3:42pm - 3:54pm
ID: 517 / 2.1: 7

FSI MODELLING OF SUB-CLINICAL LEAFLET THROMBOSIS FOLLOWING TRANSCATHETER AORTIC VALVE INTERVENTION

M. Pons Vidal¹, H. Hurrell², S. Redwood², T. Patterson², J. Lee¹

1: King's College London, United Kingdom; 2: St Thomas' Hospital, London, United Kingdom

3:54pm - 3:57pm
ID: 422 / 2.1: 8

DESIGN, IN-VITRO AND IN SILICO EVALUATION OF TWO IDEALIZED AORTIC ENDOGRAFT CONFIGURATIONS

L. Battaglia¹, M. Conti^2,3, M. Schembri³, G. Spinella⁴

1: University of Genova, Italy; 2: C3D Lab, IRCCS San Donato; 3: University of Pavia; 4: Policlinico San Martino Hospital

3:57pm - 4:00pm
ID: 684 / 2.1: 9

A SYSTEMATIC REVIEW OF MULTISCALE VENTRICULAR MODELS: BRIDGING CELLULAR MECHANICS AND GLOBAL HAEMODYNAMICS

A. Kamtikar¹, D. Donker^1,2, L. Fresiello¹

1: Cardiovascular and Respiratory Physiology, TechMed Centre, University of Twente, Enschede, The Netherlands; 2: Intensive Care Centre, University Medical Centre Utrecht, Utrecht, The Netherlands

2:30pm - 2:42pm
ID: 117 / 2.2: 1

IN-SILICO CLINICAL TRIAL OF AN INVESTIGATIONAL PULMONARY VALVE DEVICE FOR TREATING PAEDIATRIC PATIENTS

N. Götzen¹, T. Turgut¹, V. Bouwman¹, D. Oztürk², M. Bastron², S. Pasta³, G. Gentile⁴, B. Meuris⁵, S. Consortium⁶

1: 4RealSim BV, The Netherlands; 2: capvidia BV, Belgium; 3: University of Palermo, Italy; 4: IRCCS ISMETT, Italy; 5: UZ-Leuven, Belgium; 6: SimInSitu, EU

2:42pm - 2:54pm
ID: 153 / 2.2: 2

COUPLED ANATOMICAL-PHYSIOLOGICAL CALIBRATION FOR GENERATING CARDIOVASCULAR VIRTUAL POPULATIONS

B. Ghitti, J. Lang, A. Sharifzadeh-Kermani, F. Argus, M. Ragheb, G. Maso Talou

Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand

2:54pm - 3:06pm
ID: 223 / 2.2: 3

GENERATIVE MODELING WITH CONDITIONAL LDDMM FLOW MATCHING: APPLICATION TO DOMAIN UNCERTAINTY QUANTIFICATION IN HEMODYNAMICS

S. Katz¹, F. Romor¹, J.-J. Zhu², A. Caiazzo¹

1: Weierstrass Institute for Applied Analysis and Stochastics (WIAS), Germany; 2: KTH Royal Institute of Technology, Sweden

3:06pm - 3:18pm
ID: 398 / 2.2: 4

AN RBF-BASED FRAMEWORK FOR GEOMETRIC CONTROL OF CARDIOVASCULAR STATISTICAL SHAPE MODELS

A. Baldini^1,2, L. Geronzi², M. E. Biancolini¹

1: University of Rome Tor Vergata, Italy; 2: LivGemini srl, Italy

3:18pm - 3:30pm
ID: 326 / 2.2: 5

THROMBECTOMY SIMULATIONS FOR AN IN-SILICO TRIAL EVALUATING THE PERFOMANCE OF TWO STENT-RETRIEVERS

V. Fregona¹, G. Luraghi¹, L. Bontempi^2,3, T. Kuipers⁴, S. Barati¹, P. Polec⁵, M. Hoeijmakers⁶, F. Gijsen^2,3, H. Marquering⁴, C. Majoie⁴, F. Migliavacca¹, J. F. Rodriguez Matas¹

1: Politecnico di Milano, Italy; 2: Delft University of Technology, The Netherlands; 3: Erasmus Medical Center, The Netherlands; 4: Amsterdam UMC, The Netherlands; 5: ACC Cyfronet AGH, Poland; 6: Ansys

3:30pm - 3:42pm
ID: 568 / 2.2: 6

AN IN SILICO WORKFLOW FOR TAVI: SYNTHETIC COHORTS, MECHANICAL SIMULATIONS, AND DEEP LEARNING SURROGATES

J. Oldenburg¹, L. Supp¹, F. Borowski¹, M. Leuchter¹, M.-A. Weber², A. Öner¹, K.-P. Schmitz¹, M. Stiehm¹

1: Institute for ImplantTechnology and Biomaterials, Germany; 2: Institute of Diagnostic and Interventional Radiology, University Medical Center Rostock, GER

3:42pm - 3:54pm
ID: 390 / 2.2: 7

VIRTUAL STROKE PATIENT GENERATION USING GENERATIVE AI FOR IN SILICO THROMBECTOMY TRIALS

S. Verstraeten¹, T. Kuipers¹, E. Bekkers², P. Konduri^1,3, C. Majoie¹, H. Marquering¹

1: Amsterdam UMC, The Netherlands; 2: University of Amsterdam, The Netherlands; 3: Stanford University, United States

3:54pm - 3:57pm
ID: 565 / 2.2: 8

IN SILICO CLINICAL TRIAL FOR PVL EVALUATION AFTER TAVI

L. Supp¹, J. Oldenburg¹, M. Leuchter¹, J. Brüning², C. Capelli³, A. Öner¹, M.-A. Weber⁴, K.-P. Schmitz¹, M. Stiehm¹, F. Borowski¹

1: Institute for ImplantTechnology and Biomaterials e.V., Germany; 2: Institute of Computer‑assisted Cardiovascular Medicine, Charité - Universitätsmedizin Berlin, Germany; 3: Institute of Cardiovascular Science, University College London, UK; 4: Institute of Diagnostic and Interventional Radiology, University Medical Center Rostock, Germany

3:57pm - 4:00pm
ID: 683 / 2.2: 9

DEVELOPMENT AND VALIDATION OF A VIRTUAL COHORT FOR VA ECMO AND MECHANICAL VENTILATION

F. Colombi¹, D. A. M. Dias¹, D. W. Donker^1,2, F. Libera¹

1: Cardiovascular and Respiratory Physiology, TechMed Centre, University of Twente, Enschede, The Netherlands; 2: Intensive Care Center, University Medical Center Utrecht, Utrecht, The Netherlands

2:30pm - 2:42pm
ID: 386 / 2.3: 1

DEFINING RELIABILITY DOMAIN FOR PHYSICALLY REPRESENTATIVE INTERLAMELLAR FAILURE MODELLING OF ANNULUS FIBROSUS

S. Bhattacharya, M. Mengoni

Institute of Medical and Biological Engineering, University of Leeds, United Kingdom

2:42pm - 2:54pm
ID: 129 / 2.3: 2

MUSCULOSKELETAL FE MODEL OF THE LUMBAR SPINE: COMPARING HEALTHY AND PATHOLOGIC LORDOSIS

L. Carpenedo, L. La Barbera

LaBS, Dept. of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Italy

2:54pm - 3:06pm
ID: 513 / 2.3: 3

COMPARISON OF VISCOELASTIC AND BIPHASIC MODELS OF BOVINE DISC RELAXATION, CREEP AND STIFFNESS

B. Mathai, M. Alipat, S. Bhattacharya, R. Wilcox, N. Wijayathunga, M. Mengoni

Institute of Medical and Biological Engineering, University of Leeds, United Kingdom

3:06pm - 3:18pm
ID: 378 / 2.3: 4

METABOLIC RISK FOR INTERVERTEBRAL DISC STRATIFICATION, BASED ON PERSONALIZED CHEMO-MECHANICAL SIMULATIONS

E. Muñoz-Moya, C. Ruiz Wills, G. Piella, J. Noailly

BCN MedTech, Department of Engineering, Universitat Pompeu Fabra, Barcelona, Spain

3:18pm - 3:30pm
ID: 130 / 2.3: 5

MECHANO-BIOLOGICAL MODELING OF SPINAL FUSION SURGERY

D. Ninarello¹, H. Isaksson², L. La Barbera¹

1: LaBS, Dept. of Chemistry, Materials and Chemical Engineering “G. Natta”, Politecnico di Milano, Italy; 2: Department of Biomedical Engineering, Lund University, Lund, Sweden

3:30pm - 3:42pm
ID: 609 / 2.3: 6

MECHANO-METABOLISM FINITE-ELEMENT PREDICTIONS IN EARLY LUMBAR DISC DEGENERATION AND LOW BACK PAIN STRATIFICATION

E. Muñoz-Moya¹, T. McSweeney², J. Karppinen², C. Ruiz Wills¹, M. van Gils³, G. Piella¹, J. Noailly¹

1: BCN MedTech, Department of Engineering, Universitat Pompeu Fabra, Barcelona, Spain; 2: Research Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland; 3: Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

3:42pm - 3:54pm
ID: 625 / 2.3: 7

A MULTIPHYSICS PHASE-FIELD FRAMEWORK FOR FRACTURE RISK ASSESSMENT IN METASTATIC VERTEBRAE

M. Ahmadi, A. Lamprakis, N. Ovenden

Dept of Mathematics, University College London, United Kingdom

3:54pm - 3:57pm
ID: 402 / 2.3: 8

REGIONAL AND AGE-RELATED MRI-DERIVED T2 MAPPING IN HUMAN INTERVERTEBRAL DISCS

R. Benais^2,3,4, M. Pasini¹, M. Palanca¹, L. Cristofolini¹, F. Buraffaldi⁵, S. Fantoni⁵, L. Conti⁶, C. Bignardi^2,3, A. Aldieri¹

1: Department of Industrial Engineering, Alma Mater Studiorum, University of Bologna, Italy; 2: Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy; 3: PolitoBIOMedLab, Politecnico di Torino, Italy; 4: Institute of Continuum Mechanics and Biomechanics, Friedrich-Alexander-University Erlangen-Nuremberg, Germany; 5: Medical Technology Laboratory, IRCCS Istituto Ortopedico Rizzoli, Italy; 6: Department of Physics and Astronomy, Alma Mater Studiorum, University of Bologna, Italy

3:57pm - 4:00pm
ID: 415 / 2.3: 9

KNEEVIEW: AN OPEN-SOURCE REPOSITORY OF PATIENT-SPECIFIC KNEE GEOMETRIES AND STRUCTURED MESHES

R. Janssen¹, S. Natarajan¹, F. Chemorion¹, I. Radalov³, J. Monfort Faure^4,5, M. A. González Ballester^1,2, J. Noailly¹

1: Universitat Pompeu Fabra, Spain; 2: ICREA, Spain; 3: Department of Radiology, Hospital Del Mar, Spain; 4: Rheumatology service, Hospital Del Mar, Spain; 5: Hospital del Mar Research Institute, Inflammation and Cartilage Research Group, Spain

2:30pm - 2:42pm
ID: 228 / 2.4: 1

PHYSIOME LINKS (PHLYNX): A WEB-BASED TOOL FOR MODULAR, MULTISCALE MODEL COUPLING AND DEVELOPMENT

J. M. Dowrick, F. Argus, H. Sorby

Auckland Bioengineering Institute, New Zealand

2:42pm - 2:54pm
ID: 316 / 2.4: 2

SEMANTIC ANNOTATION FOR COMPUTATIONAL BIOLOGICAL MODELS

L. W. Santoso, W. Ai, K. Tran, D. Nickerson

University of Auckland, New Zealand

2:54pm - 3:06pm
ID: 323 / 2.4: 3

THE ACUTE PHASE RESPONSE TO BURN INJURY: AN IN SILICO MODELLING APPROACH

R. V. Bumbuc^1,2,3, V. M. Sheraton³, P. P. Mulder^1,5,6,8, B. K. H. L. Boekema^1,5,6, A. G. Hoekstra³, P. P. P. M. van Zuijlen^1,4,5,6,7, H. I. Korkmaz^1,2,4,6

1: Department of Plastic, Reconstructive and Hand Surgery, Amsterdam Movement Sciences (AMS) Institute, Amsterdam University Medical Center (UMC), VUmc location, The Netherlands; 2: Department of Molecular Cell Biology and Immunology, Amsterdam Infection and Immunity (AII) Institute, Amsterdam University Medical Center (UMC), VUmc location, The Netherlands; 3: Computational Science Lab, Informatics Institute, faculty of Science, University of Amsterdam, The Netherlands; 4: Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, Beverwijk, The Netherlands; 5: Burn Research Lab, Beverwijk, The Netherlands; 6: Alliance of Dutch Burn Care, Beverwijk, The Netherlands; 7: Amsterdam UMC location University of Amsterdam, Pediatric Surgical Centre, Emma Children’s Hospital, The Netherlands; 8: Civil-Military Centre of Expertise for Trauma Care (CETC), Central Military Hospital, Ministry of Defence, Utrecht, The Netherlands

3:06pm - 3:18pm
ID: 433 / 2.4: 4

THE PHYSIOME MODEL REPOSITORY: CURRENT STATUS AND FUTURE PLANS

D. Nickerson, T. Yu, A. Garny, A. Kyaw Hein, P. Hunter

Auckland Bioengineering Institute, University of Auckland, New Zealand

3:18pm - 3:30pm
ID: 438 / 2.4: 5

TOWARDS A REACTION-DIFFUSION FRAMEWORK FOR IN SILICO ASSESSMENT OF HEALING IN BREAST-CONSERVING SURGERY

O. De Becker¹, J. Vander Sloten¹, L. Geris^1,2

1: KU Leuven, Belgium; 2: ULiège, Belgium

3:30pm - 3:42pm
ID: 506 / 2.4: 6

DHPI: A MULTISCALE MODEL FOR DRUG–HOST–PATHOGEN DYNAMICS IN INFECTIOUS DISEASE

A. Ravoni¹, E. Mastrostefano¹, D. Moretti¹, E. Onofri¹, F. Pelusi¹, P. Tieri¹, F. Castiglione^1,5, A. Dokoumetzidis^2,3, E. Karakitsios¹, S. D’Agate⁴, A. Di Deo⁴, U. Villani⁴, O. Della Pasqua⁴

1: Institute for Applied Mathematics "Mauro Picone", CNR, Rome, Italy; 2: Department of Pharmacy, University of Athens, Athens, Greece; 3: Pharma-Informatics Unit, Athena Research Center, Marousi, Greece; 4: Clinical Pharmacology and Therapeutics Group, University College London, London, UK; 5: Medicine Department - Pulmonary Systems Medicine, University of Florida, Gainesville, FL 32610, USA

3:42pm - 3:54pm
ID: 648 / 2.4: 7

BRIDGING PHARMACOKINETICS, PHARMACODYNAMICS AND PHARMACOGENOMICS WITH PHARMACOLIBRARY – FREE LIBRARY TO MODEL PHARMACOLOGY

T. Kulhánek, S. Denil, G. Ertaylan

VITO, Belgium

3:54pm - 3:57pm
ID: 585 / 2.4: 8

PERSONALIZED SIMULATION USING FINITE ELEMENTS OF MULTI-NEEDLE INSERTION IN PROSTATE BRACHYTHERAPY

C. P. Papanikas¹, E. Sellountos¹, E. Ioannou¹, V. Vavourakis²

1: University of Cyprus, Cyprus; 2: University College London, United Kingdom

2:30pm - 2:42pm
ID: 273 / 2.5: 1

MODELLING CEREBRAL AUTOREGULATION ACROSS SCALES: FROM HEALTH TO POST-STROKE DYSFUNCTION

C. Lambride^1,2,3, M. El Amki^1,2, S. Wegener^1,2, F. Schmid³

1: Department of Neurology, University Hospital and University of Zurich, Switzerland; 2: Neuroscience Center Zurich, University of Zurich, Switzerland;; 3: ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland

2:42pm - 2:54pm
ID: 420 / 2.5: 2

DIGITAL TWIN-DRIVEN MODELLING OF INTRACRANIAL ANEURYSM CARE PATHWAYS

L. Bührer^1,2, A. Sandralegar^3,4, S. Morel⁵, P. Bijlenga^3,4, S. Hirsch¹, G. R Spinner¹

1: Centre for Computational Health, Institute of Computational Life Sciences, Zurich University of Applied Sciences, Wädenswil, Switzerland; 2: Department of Mathematical Modeling and Machine Learning, University of Zurich, Zürich, Switzerland; 3: Division of Neurosurgery, Geneva University Hospitals, Geneva, Switzerland; 4: Faculty of Medicine, University of Geneva, Geneva, Switzerland; 5: HUG NeuroCentre, Geneva University Hospitals, Geneva, Switzerland

2:54pm - 3:06pm
ID: 599 / 2.5: 3

TWIN MODELS OF SURVIVAL IN PATIENTS WITH GLIOBLASTOMA USING NORMATIVE NEUROIMAGING

A. Janus^1,2, J. Falcó-Roget¹, B. Wojtarowicz¹, J. Rybska¹, C. di Paola³, A. Ielo⁴, S. Lillo^5,6, L. S. Politi^7,8, J. K. Argasiński^1,2, A. Cacciola^7,8

1: Sano Centre for Computational Medicine, Poland; 2: Jagiellonian University, Poland; 3: University of Messina, Italy; 4: RCCS Centro Neurolesi "Bonino Pulejo", Italy; 5: CNAO National Center for Oncological Hadrontherapy, Italy; 6: University of Pavia, Italy; 7: Humanitas University, Italy; 8: RCCS Humanitas Research Hospital, Italy

3:06pm - 3:18pm
ID: 602 / 2.5: 4

CEREBROSPINAL FLUID DYNAMICS AND BRAIN TISSUE POROMECHANICS FOR THE STUDY OF WASTE CLEARANCE

I. Fumagalli, M. Corti, R. Petrucci, N. Parolini, P. F. Antonietti

MOX, Dipartimento di Matematica, Politecnico di Milano, Italy

3:18pm - 3:30pm
ID: 655 / 2.5: 5

AN ALLOMETRIC AND ANISOTROPIC APPROACH TO PREDICTING CRANIAL GROWTH

M. Potgieter, D. Finlay, J. McLaughlin, S. Bozkurt

School of Engineering, Ulster University, United Kingdom

3:30pm - 3:42pm
ID: 248 / 2.5: 6

IN-SILICO MEDICINE APPLICATION OF MULTIMODAL NEUROIMAGING BIOMARKERS IN ALZHEIMER’S DISEASE

A. Vernone, C. D'Agostino, I. Stura, E. Ficiarà, C. Guiot, F. Pizzagalli

University of Turin, Italy

3:42pm - 3:45pm
ID: 466 / 2.5: 7

AN UNCERTAINTY-AWARE FRAMEWORK FOR SAFE EEG-BASED STROKE TRIAGE

R. Blanco¹, M. N. van Stigt³, E. A. Groenendijk³, J. K. Argasiński^1,2, J. M. Coutinho³, A. Lisowska⁴, H. A. Marquering³

1: Sano Centre for Computational Medicine, Poland; 2: Jagiellonian University, Poland; 3: Dept. of Neurology / Radiology and Nuclear Medicine / Biomedical Engineering and Physics, Amsterdam University Medical Center, the Netherlands; 4: Vrije Universiteit / Amsterdam University Medical Center, the Netherlands

3:45pm - 3:48pm
ID: 485 / 2.5: 8

CT-DERIVED LESION DESCRIPTORS AND COMPUTATIONAL MODELLING OF INTRACRANIAL HAEMORRHAGE

H. Kelsey¹, F. Lecky¹, T. Vande Vyvere², A. Marzo¹, N. Wang¹, X. Yu¹

1: The University of Sheffield, United Kingdom; 2: Antwerp University Hospital, Belgium

3:48pm - 3:51pm
ID: 492 / 2.5: 9

A GOVERNED BAYESIAN DIGITAL TWIN FOR PARKINSON’S DISEASE PROGRESSION MONITORING WITH UNCERTAINTY GATED REPORTING

A. hemedan

Luxembourg institute of health, Luxembourg

3:51pm - 3:54pm
ID: 666 / 2.5: 10

ESTABLISHING A CLINICALLY VALIDATED PATIENT-SPECIFIC VIRTUAL PROCEDURE FOR MECHANICAL THROMBECTOMY

R. Wu¹, N. Ruseckaite², A. H. Ashok³, T. Matys³, Y. Joshi³, R. Mudkavi⁴, G. Toumbas⁵, J. Kaggie³, N. Evans⁶, S. Singh-Gryzbon²

1: Dept of Chemical and Environmental Engineering, Yale University, Connecticut, US; 2: Dept of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; 3: Dept of Radiology, University of Cambridge, Cambridge, UK; 4: East & North Hertfordshire Teaching NHS Trust, Stevenage, UK; 5: School of Clinical Medicine, University of Cambridge, Cambridge, UK; 6: Dept of Clinical Neurosciences, University of Cambridge, Cambridge, UK

2:30pm - 2:42pm
ID: 178 / 2.6: 1

PHYSICS-BASED SYNTHETIC X-RAY IMAGE GENERATION FOR IMPROVING DEEP LEARNING IN MEDICAL IMAGING

A. Allain, N. Crolais, C. Hatton

Scalian, France

2:42pm - 2:54pm
ID: 494 / 2.6: 2

DESIGN OF A ROBUST CNN FOR CANCER DETECTION IN MAMMOGRAPHY IMAGES

E. Raina^1,2, M. Oria^1,2, M. Salvi², A. Manzin¹

1: Istituto Nazionale di Ricerca Metrologia, Italy; 2: Politecnico di Torino, Italy

2:54pm - 3:06pm
ID: 374 / 2.6: 3

SIMULTANEOUS 4D ULTRASOUND AND HIGH-DENSITY ELECTROMYOGRAPHY ACQUISITION OF THE HUMAN TIBIALIS ANTERIOR DURING DYNAMIC MUSCLE CONTRACTION

P. Zhang¹, L. Vosse², G. Cerone^3,4, A. Botter^3,4, T. Siebert², O. Roehrle¹

1: Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Germany; 2: Institute of Sport and Movement Science, University of Stuttgart, Germany; 3: Laboratory for Engineering of the Neuromuscular System (LISiN), Department of Electronics and Telecommunications, Politecnico di Torino, Italy; 4: PoliToBIOMed Laboratory, Politecnico di Torino, Turin, Italy

3:06pm - 3:18pm
ID: 207 / 2.6: 4

AUTOMATED IN VIVO ULTRASOUND QUANTIFICATION OF THORACOLUMBAR FASCIA THICKNESS AND GLIDING

c. g. fontanella, l. bonaldi, c. pirri, c. stecco, F. Uccheddu

University of Padova, Italy

3:18pm - 3:30pm
ID: 346 / 2.6: 5

CT-BASED THROMBUS MECHANICAL PHENOTYPING IN ACUTE ISCHEMIC STROKE

L. Bontempi^1,2, J. Cruts¹, R. Cahalane^1,3, N. Boodt¹, D. Bos¹, B. Fereidoonnezhad², P. J. van Doormaal¹, A. van der Lugt¹, D. Dippel¹, F. Gijsen^1,2

1: Erasmus MC, University Medical Center, Rotterdam, the Netherlands; 2: Delft University of Technology, Delft, the Netherlands; 3: University of Limerick, Limerick, Ireland

3:30pm - 3:42pm
ID: 151 / 2.6: 6

TOWARDS TREATMENT DECISION SUPPORT: VALIDATING A PERSONALISED COLLATERAL DIGITAL TWIN WITH IMAGING-DERIVED COLLATERAL SCORES

J.-F. Kuo¹, T. Józsa², S. Payne³, W. Olszewski⁴, C. Majoie⁴, H. Marquering⁴, A. Hoekstra¹

1: University of Amsterdam, Netherlands, The; 2: Cranfield University, UK; 3: University of Bristol, UK; 4: Amsterdam UMC Location, University of Amsterdam, Netherlands, The

3:42pm - 3:45pm
ID: 138 / 2.6: 7

CLASSIFICATION OF PLACENTA ACCRETA SPECTRUM USING MACHINE LEARNING AND TEXTURE ANALYSIS OF MR IMAGES

S. Coldman^1,2, G. Zhou^1,2, D. Wu^1,2, L. Guo^1,2, A. Melbourne³, A. David⁴, N. Mufti⁵, L. Gherardini⁶, J. Sousa^6,7, E. Whitby⁸, X. Li^1,2

1: University of Sheffield, UK; 2: Insigneo Institute, UK; 3: King's College London, UK; 4: University College London, UK; 5: Imperial College Healthcare, UK; 6: Computational Intelligence, Sano Centre for Computational Personalised Medicine, Poland; 7: Multidisciplinary Institute of Ageing, MIA-Portugal, University of Coimbra, Portugal; 8: Sheffield Teaching Hospitals

3:45pm - 3:48pm
ID: 157 / 2.6: 8

BONE RESECTION PLANNING IN MIXED REALITY FOR BONE IMPLANT FITTING IN THE CALCANEUS (A CASE STUDY)

G. Magrini^1,2, M. Stanuch², A. Skalski^3,2

1: Politecnico di Milano, Italy; 2: MedApp S.A., Poland; 3: AGH University of Krakow, Poland

3:48pm - 3:51pm
ID: 676 / 2.6: 9

UNSUPERVISED CLUSTERING OF TRABECULAR BONE MICRO-CT RECOVERS STRUCTURAL PATTERNS MATCHING FINITE-ELEMENT STRESS

L. Wang¹, J. Chen¹, J. Meakin², I. Sucala¹, K. Knapp³

1: Department of Engineering, University of Exeter, Exeter, United Kingdom; 2: Department of Physics and Astronomy, University of Exeter, Exeter, United Kingdom; 3: Department of Health and Care Professions, University of Exeter, Exeter, United Kingdom

2:30pm - 2:42pm
ID: 142 / 2.7: 1

GEOMETRIC VERSUS CONSTITUTIVE EFFECTS OF VOCAL FOLD LESIONS: A FLUID–STRUCTURE INTERACTION STUDY

A. Niyingenera, N. Delaney, R. Zakerzadeh

Duquesne University, United States of America

2:42pm - 2:54pm
ID: 278 / 2.7: 2

SURGICAL RESPONSE PREDICTION IN CTEPH FROM TWO INDEPENDENT CENTRES USING HAEMODYNAMIC MODELLING

B. Shaarbaf Ebrahimi¹, H.-F. Chan¹, P. Khwaounjoo¹, F. Argus¹, G. Jin¹, X. Ma¹, M. Nash¹, D. Kaye², M. Dagan², A. Doi², D. Kiely³, A. Swift³, J. Wild³, D. McGiffin², M. Tawhai¹

1: University of Auckland, New Zealand; 2: Alfred Hospital, Melbourne, Australia; 3: School of Medicine and Population Health, University of Sheffield, UK

2:54pm - 3:06pm
ID: 123 / 2.7: 3

A DIGITAL TWIN PIPELINE FOR AUTOMATED PULMONARY EMBOLISM BIOMARKER EXTRACTION

M. des Ligneris¹, N. Painchaud¹, A. Serva^2,3, L. Bertoletti³, P. Croisille^1,4, C. Frindel^1,5, O. Merveille¹

1: Univ Lyon, INSA‐Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1294, F‐69621, Lyon, France; 2: Department of Pneumology, CHU Saint-Etienne, UJM Saint-Etienne, France; 3: Université Jean Monnet Saint-Étienne, CHU Saint-Étienne, Mines Saint-Étienne, INSERM, SAINBIOSE U1059, CIC 1408, Département de Médecine Vasculaire et Thérapeutique, F-CRIN INNOVTE network, all in F-42055, Saint-Étienne, France; 4: Department of Radiology, CHU Saint-Etienne, UJM Saint-Etienne, France; 5: IUF, Institut Universitaire de France, Paris, France

3:06pm - 3:18pm
ID: 176 / 2.7: 4

AN IN SILICO APPROACH TO HIGHLIGHT THE SIGNIFICANCE OF THE TIME CONSTANT OF ALVEOLAR RECRUITMENT

R. Dunphy¹, S. Quicken¹, J. van Kimmenade¹, J. Mangold², M. Shekarnabi^2,3, V. Estopier Castillo², M. Orkisz³, A. De Bie Dekker⁴, I. Paulussen⁴, J.-C. Richard^3,5, W. Huberts¹, S. Bayat^2,6

1: Cardiovascular Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; 2: Grenoble Alpes University, STROBE Laboratory, Inserm UA07, Grenoble, France; 3: Université Claude Bernard Lyon, INSA-Lyon, CNRS, Inserm, CREATIS UMR 5220, U1294, Lyon, France; 4: Department of Intensive Care, Catharina Hospital Eindhoven, Eindhoven, The Netherlands; 5: Hospices Civils de Lyon, Croix Rousse Hospital, Department of Intensive Care, Lyon, France; 6: Grenoble University Hospital, Department of Pulmonology and Clinical Physiology, Grenoble, France

3:18pm - 3:30pm
ID: 591 / 2.7: 5

AI-BASED NEURAL IMPLICIT MODELLING OF THE PEDIATRIC TRACHEA FOR DATA-DRIVEN MEDICAL DEVICE DESIGN

L. Hijazi, F. Berro, A. Malek, B. Kose

Istanbul Medipol University, Turkiye

3:30pm - 3:42pm
ID: 382 / 2.7: 6

THE HUMAN AIRWAYS REGISTER: A WEB DATABASE TO STANDARDISE IN SILICO LUNG GEOMETRY

M. K. Ola¹, M. Seal², R. A. Sarwar¹, S. K. Mattireddy¹, C. E. Brightling^3,4, K. Burrowes², H. Kaul^1,3,4

1: School of Engineering, University of Leicester, UK; 2: Auckland Bioengineering Institute, University of Auckland, New Zealand; 3: Institute for Lung Health, Leicester NIHR BRC, Leicester, UK; 4: Department of Respiratory Sciences, University of Leicester, Leicester, UK

3:42pm - 3:45pm
ID: 563 / 2.7: 7

NETWORK-BASED DIGITAL TWINS REVEAL AIR POLLUTION MODIFIES GENETIC DISEASE SUSCEPTIBILITY THROUGH SHARED INFLAMMATORY PATHWAYS

A. Maertens, D. Ukaegbu, A. Kim

Johns Hopkins Bloomberg School of Public Health, United States of America

3:45pm - 3:48pm
ID: 383 / 2.7: 8

VIRTUAL POPULATIONS: GENERATING PHENOTYPE-SPECIFIC LUNG GEOMETRY USING CONDITIONAL AUTOENCODER

J. John¹, K. Burrowes¹, J. O'Sullivan², S. Bhatt³, E. Hoffman⁴, M. Tawhai¹

1: Auckland Bioengineering Institute, The University of Auckland, NZ; 2: Liggins Institute, The University of Auckland, NZ; 3: Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; 4: Departments of Radiology and Biomedical Engineering, University of Iowa, Iowa, USA

3:48pm - 3:51pm
ID: 611 / 2.7: 9

PHYSIOLOGICAL CLOSED-LOOP CONTROL MODEL IN SIMSCAPE FOR AUTOMATED VENTILATION STRATEGY VALIDATION

M. Nord, V. Suomi

MathWorks, France

3:51pm - 3:54pm
ID: 675 / 2.7: 10

IN-VIVO EVALUATION OF A 3D-PRINTED PLA-PCL TRACHEAL STENT IN A RABBIT MODEL.

L. Cella¹, L. Vilalta Solé², M. Malvè³, J. Rosell Tormo⁴, N. Gómez Martín⁵, R. Fernández Parra⁵

1: Doctoral School of the Catholic University of Valencia, Spain; 2: Veterinary Hospital Canis, Spain; 3: Public University of Navarre (UPNA), Spain; 4: Valencian Institute of Pathology, Spain; 5: Veterinary Referral Hospital UCV, Catholic University of Valencia San Vicente Mártir, Spain

3:54pm - 3:57pm
ID: 685 / 2.7: 11

IN-SILICO ASSESSING THE RISK OF DIFFERENTIAL HYPOXIA AND O2 DISTRIBUTION DURING PERIPHERAL VA ECMO TREATMENTS

A. Ruggeri¹, M. Belliato², M. Conti¹

1: Department of Civil Engineering and Architecture, University of Pavia, Pavia, Italy; 2: UOC Anestesia e Rianimazione 1, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

3:57pm - 4:00pm
ID: 686 / 2.7: 12

FROM LOCAL AIRWAY OBSTRUCTION TO GLOBAL RESPIRATORY IMPEDANCE: AN IN SILICO STUDY IN THE NEONATAL LUNG

M. Mentasti, R. Dellacà, C. Veneroni

Politecnico di Milano, Italy

5:00pm - 5:12pm
ID: 483 / 3.1: 1

RADIOMICS-BASED ATRIAL FLOW PROFILE DESCRIPTION FROM 4D FLOW MRI IN ATRIAL FIBRILLATION PATIENTS

C. Cortesi^1,2, G. Diotallevi¹, L. Alinezhad¹, P. Maleki¹, M. Falanga¹, J. Leite², N. Kachenoura², C. Corsi¹

1: DEI, University of Bologna, Italy; 2: Sorbonne Université, CNRS, INSERM, LIB, Paris, France

5:12pm - 5:24pm
ID: 125 / 3.1: 2

SHUNT HEMODYNAMICS ABNORMALITIES IN SUBLINGUAL MICROCIRCULATION AS INDICATION FOR SEPSIS

K. Vishnu¹, M. Hilty², A. Candreva², M. Colombo¹

1: Aarhus University, Denmark; 2: Zurich University Hospital, Switzerland

5:24pm - 5:36pm
ID: 345 / 3.1: 3

BAYESIAN INFERENCE OF SEPSIS HAEMODYNAMICS FROM ARTERIAL BLOOD PRESSURE AND PHOTOPLETHYSMOGRAPHY

H. Vaidya¹, R. Shipley¹, S. Harris¹, F. Catling^1,2

1: University College London, United Kingdom; 2: Imperial College London, United Kingdom

5:36pm - 5:48pm
ID: 413 / 3.1: 4

VALIDATION OF A VIRTUAL-POPULATION-BASED APPROACH FOR NON-INVASIVE CARDIOVASCULAR MONITORING IN HEALTHY VOLUNTEERS

B. M. Laudenzi¹, P. Yevtushenko², L. Omar Müller¹

1: Laboratory of Mathematics for Biology and Medicine, Department of Mathematics, University of Trento, Trento, Italy; 2: Institute of Computer-assisted Cardiovascular Medicine, Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany

5:48pm - 6:00pm
ID: 610 / 3.1: 5

PARAMETER ESTIMATION IN CARDIOVASCULAR FLUID–SOLID INTERACTION

D. Nolte, R. Aróstica, C. Bertoglio

University of Groningen, Netherlands, The

5:00pm - 5:12pm
ID: 332 / 3.2: 1

MODEL-BASED NON-INVASIVE RECONSTRUCTION OF PATIENT-SPECIFIC LEFT VENTRICLE PRESSURE-VOLUME DYNAMICS

R. Manoj¹, A. Caenen^2,3, L. Wouters², J.-U. Voigt², J. D’hooge², L. R. Hellevik¹

1: Division of Biomechanics, Department of Structural Engineering, Norwegian University of Science and Technology, Norway; 2: Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium; 3: Institute for Biomedical Engineering and Technology, Ghent University, Ghent, Belgium

5:12pm - 5:24pm
ID: 499 / 3.2: 2

DEMOGRAPHIC BIASES IN AI-ECG-BASED PREDICTION OF ATRIAL FIBRILLATION

B. G. van Willigen^1,2, M. M. Terpstra¹, C. M. Buck⁴, H. Bleijendaal¹, T. F. Brouwer¹, R. Coronel¹, H. A. Marquering^2,3, J. R. Groot¹

1: Experimental cardiology, Amsterdam UMC, The Netherlands; 2: Biomedical engineering & physics, Amsterdam UMC, The Netherlands; 3: Radiology and Nuclear Medicine, Amsterdam UMC, The Netherlands; 4: Cardiovascular Biomechanics, Eindhoven University of Technology, The Netherlands

5:24pm - 5:36pm
ID: 621 / 3.2: 3

A COMBINED IN SILICO APPROACH FOR THE DESIGN OPTIMIZATION OF A RIGHT VENTRICULAR ASSIST DEVICE

I. Guidetti¹, C. Yildirim², E. Cutrì³, K. Caliskan⁴, G. Guven⁵, O. Soliman², K. Pekkan⁶, F. De Gaetano¹

1: Politecnico di Milano, Italy; 2: Royal College of Surgeons in Ireland, Ireland; 3: Université de technologie de Compiègne, France; 4: Erasmus Medical Center, Netherlands; 5: Hacettepe University, Turkey; 6: The Ohio State University, USA

5:36pm - 5:48pm
ID: 195 / 3.2: 4

FROM RAW SEGMENTATIONS TO COMPUTATIONAL MESHES: AN AUTOMATED FRAMEWORK APPLIED TO THE HUMAN HEART

F. Fabbri¹, M. A. Scarpolini^1,2, F. Tudisco^1,3, F. Viola^1,2

1: Gran Sasso Science Institute, Italy; 2: INFN Roma Tor Vergata, Italy; 3: The University of Edinburgh, UK

5:48pm - 6:00pm
ID: 572 / 3.2: 5

EFFECTS OF RESPIRATORY HRV ON CARDIAC WORK

C. Kohombakadawala¹, T. Pham^1,2, K. Tran¹, A. Taberner^1,2, J.-C. Han¹

1: Auckland Bioengineering Institute, University of Auckland, New Zealand; 2: Department of Engineering Science and Biomedical Engineering, University of Auckland, New Zealand

5:00pm - 5:12pm
ID: 236 / 3.3: 1

GLOBAL SENSITIVITY ANALYSIS OF A LINEAR FINITE ELEMENT MODEL FOR THE PREDICTION OF FEMORAL STRENGTH

A. Levillain¹, M. Gardegaront¹, D. Brizard¹, C. B. Confavreux^2,3,4, J.-B. Pialat^2,5, H. Follet⁴, D. Mitton¹

1: Univ Lyon, Univ Eiffel, UCBL, LBMC UMR_T9406, France; 2: HCL, Centre hospitalier Lyon Sud, France; 3: CEMOS, Service de Rhumatologie, IC-HCL, France; 4: Univ Lyon, UCBL, INSERM, LYOS UMR 1033, France; 5: INSA-Lyon, CREATIS UMR5220, UCBL, France

5:12pm - 5:24pm
ID: 250 / 3.3: 2

AI-BASED FULLY AUTOMATIC FEMUR SEGMENTATION FROM CT SCANS FOR METASTATIC PATIENT-SPECIFIC FE MODELS

E. Bruatto¹, C. Curreli², B. Dozza³, L. Campanacci¹, A. A. La Mattina²

1: 3rd Orthopaedic and Traumatologic Clinic Prevalently Oncologic, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; 2: Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; 3: Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

5:24pm - 5:36pm
ID: 315 / 3.3: 3

RETHINKING BIONIC LIMBS: CAN DIGITAL TWINS ENHANCE CLINICAL DECISION-MAKING?

L. Frossard¹, A. Bavil¹, C. Langton^1,2, S. Feih³, S. Latimer¹, J. Maharaj¹, C. Pizzolato¹, R. Barrett¹, D. Lloyd^1,2

1: Australian Centre for Precision Health and Technology (PRECISE), Griffith University, Australia; 2: Advanced Design Prototyping Technologies Institute (ADaPT), Griffith University, Australia; 3: National Health and Medical Research Council Centre of Research Excellence in Wiser Wound Care, Griffith University, Australia

5:36pm - 5:48pm
ID: 573 / 3.3: 4

BENEFITS IN TERMS OF FIT-AND-FILL AND PRIMARY STABILITY OF A OSTEOCUSTOM STEM FOR TRANSFEMORAL AMPUTEES

G. Galteri¹, S. Casadei¹, E. Hirschberg¹, D. Alesi², S. Zaffagnini², K. Morellato³, E. Gruppioni³, L. Cristofolini¹

1: University of Bologna, Italy; 2: IRCCS Istituto Ortopedico Rizzoli, Italy; 3: Centro Protesi INAIL, Vigorso di Budrio, Bologna, Italy

5:48pm - 6:00pm
ID: 617 / 3.3: 5

HIP FRACTURE RISK ASSESSMENT WITH A PARABOLOIDAL PLASTICITY MODEL IN ABAQUS AND MOFEM: COMPARING FRACTURE DISCRIMINATION

A. Moslemi (1)¹, E. Alizadeh (1)¹, V V S V. Jakka (1)¹, C. J. Runcie (2)², A. G. Shvarts (2)², Ł. Kaczmarczyk (2)², C. Ruiz Wills (1)¹, L. del Rio (3)³, S. Di Gregorio (3)³, L. Humbert (4)⁴, J. Noailly (1)¹

1: Universitat Pompeu Fabra, Spain; 2: lasgow Computational Engineering Centre (GCEC), University of Glasgow, UK;; 3: CETIR Ascires, Spain; 4: 3D-Shaper Medical, Spain

5:00pm - 5:12pm
ID: 149 / 3.4: 1

TOWARDS ORGAN SCALE MODELING OF THE VASCULAR MICROENVIRONMENT

N. Dimola, P. Vitullo, P. Zunino

Politecnico di Milano, Italy

5:12pm - 5:24pm
ID: 159 / 3.4: 2

HETEROGENOUS TUMOR MICROENVIRONMENT IN NON-SMALL CELL LUNG CANCER DERIVED FROM FDG-PET DATA

G. Nævdal¹, I. R. Jarczyk², T. Haslerud^3,4, S. Evje²

1: NORCE Research AS, Norway; 2: University of Stavanger, Norway; 3: Stavanger University Hospital, Norway; 4: Haukeland University Hospital, Norway

5:24pm - 5:36pm
ID: 215 / 3.4: 3

MULTISCALE THERAGNOSTIC DIGITAL TWIN FOR PREDICTING RADIOPHARMACEUTICAL UPTAKE IN RENAL CELL CARCINOMA

L. Cavinato, A. Pottier

Politecnico di Milano, Italy

5:36pm - 5:48pm
ID: 259 / 3.4: 4

DIGITAL TWINS FOR PERSONALIZED PLANNING OF LIVER CANCER TREATMENTS

E. Sangiorgio^1,2, M. Salvi¹, S. Andreetta³, V. Mazzi¹, G. De Nisco¹, G. Isu³, D. Gallo¹, U. Morbiducci¹

1: Politecnico di Torino, Italy; 2: Università degli Studi di Palermo, Italy; 3: Medics srl, Italy

5:48pm - 6:00pm
ID: 503 / 3.4: 5

INCORPORATING ADC-DERIVED HYPOXIC SUBVOLUMES INTO PERSONALIZED TCP MODELLING IN HEAD-AND-NECK CANCER

E. Longhi¹, V. Cortella², E. Gioscio¹, N. A. Iacovelli¹, M. Franceschini¹, G. Calareso¹, A. Cavallo¹, M. Dassie¹, L. Possenti¹, P. Zunino², E. Orlandi³, T. Rancati¹

1: Department of Epidemiology and Data Science/Dept of Imaging Diagnostics and Radiotherapy Fondazione IRCCS Istituto Nazionale dei Tumori, Italy; 2: Department of Mathematics, Politecnico di Milano, Italy; 3: Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Campus della Salute, Policlinico San Matteo, Italy

5:00pm - 5:12pm
ID: 121 / 3.5: 1

OPTIMIZATION OF A DOUBLE FLOW CANNULA FOR AN ECMO DEVICE THROUGH COMPUTATIONAL MODELLING

P. Varsos¹, M. Graffin¹, S. Fleurot², L. Aubrege², J. Issard^2,3, O. Mercier^2,3, I. Vignon-Clementel¹

1: Inria; 2: Innovation and Preclinical Research Department, Hôpitaux Paris Saint-Joseph et Marie Lannelongue; 3: Department of Thoracic Surgery, Marie Lannelongue Hospital

5:12pm - 5:24pm
ID: 185 / 3.5: 2

GEOMETRIC ANALYSIS OF THE PULMONARY ARTERY OF HEART FAILURE PATIENTS: DEVICE LANDING ZONE ASSESSMENT

J. Brüning¹, N. Solowjowa¹, A. Laube¹, L. Kretztler¹, K. Srikantharajah², J. Romberg², C. Frottier², A. Schlief¹, L. Goubergrits¹

1: Deutsches Herzzentrum der Charité, Germany; 2: BIOTRONIK SE & Co. KG, Germany

5:24pm - 5:36pm
ID: 144 / 3.5: 3

VORTEX DURATION ASSESSMENT IN SEVERE PULMONARY ARTERIAL HYPERTENSION

M. Sabry^1,2, A. Hassan^2,3, M. H. Yacoub^1,4, P. Lamata¹, A. De Vecchi¹

1: Department of Biomedical Engineering, King's College London, United Kingdom; 2: Aswan Heart Centre, Magdi Yacoub Foundation (MYF), Egypt; 3: Cardiology Department, Cairo University, Egypt; 4: National Heart and Lung Institute, Imperial College London, UK

5:36pm - 5:48pm
ID: 330 / 3.5: 4

COMPUTATIONAL MODELLING OF THE CARDIOVASCULAR ADAPTATION IN PULMONARY ARTERIAL HYPERTENSION

S. Schomaker¹, C. Lokhorst², D. Nolte¹, R. Berger², T. Willems², J. Douwes², C. Bertoglio¹

1: University of Groningen, Netherlands, The; 2: University Medical Center Groningen, Netherlands, The

5:48pm - 6:00pm
ID: 361 / 3.5: 5

UNVEILING CARDIOVASCULAR CHANGES AFTER LUNG RESECTION USING COMPUTATIONAL MODELS

S. Huang, R. Good, P. McCall, S. McGinty, B. Shelley, A. Aggarwal

University of Glasgow, United Kingdom

5:00pm - 5:12pm
ID: 164 / 3.6: 1

COUPLED NUMERICAL–EXPERIMENTAL MODELING OF THE HUMAN SEMICIRCULAR CANAL

M. Blaise¹, E. Puyoo¹, A.-S. Poudrel², N. Totaro², F. Girardin², P. Reynard³, D. Baumgartner⁴, A. Charpiot^4,5, L. Roiban⁶, E. Ionescu³

1: INL UMR5270 CNRS, INSA Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France; 2: LVA, UR677, INSA Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France; 3: Hospices Civils de Lyon, France; 4: ICube UMR7357 CNRS, Université de Strasbourg, France; 5: Hôpitaux Universitaires de Strasbourg, France; 6: MatéIS UMR5510 CNRS, INSA Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France

5:12pm - 5:24pm
ID: 350 / 3.6: 2

A COLLABORATIVE CALL TOWARDS VIRTUAL KIDNEYS AND PHYSIOLOGY-BASED MODELS OF ACUTE KIDNEY INJURY

F. J. López-Hernández^1,2

1: Instituto de Investigación Biomédica de Salamanca, Spain; 2: Universidad de Salamanca, Spain

5:24pm - 5:36pm
ID: 381 / 3.6: 3

PERSONALISED MODELLING OF MEAL MACRONUTRIENT EFFECTS ON GLUCOSE RESPONSE

R. Naranpanawa¹, K. Nanthakumar¹, J. M. Dowrick¹, G. Chase², G. D. Maso Talou¹, M. Tawhai¹, F. Argus¹

1: University of Auckland, New Zealand; 2: University of Canterbury, New Zealand

5:36pm - 5:48pm
ID: 502 / 3.6: 4

PROPOSAL OF A PHYSICS INFORMED NEURAL NETWORK FRAMEWORK AS DIGITAL TWIN FOR EARLY SEPSIS DETECTION

P. K. Govarthan¹, D. Vijayarajan², H. Sundaresan², S. Sudhakar¹, R. Swaminathan¹

1: Department of Applied Mechanics and Biomedical Engineering, Indian Institute of Technology Madras, Chennai, India; 2: Department of Electronics and Communication Engineering, College of Engineering, Guindy, Anna University, Chennai, India

5:48pm - 6:00pm
ID: 549 / 3.6: 5

MODELING INCRETIN SECRETION AND EFFECTS IN RESPONSE TO VARIOUS MEAL CHALLENGES

J. Müller¹, S. O'Donovan¹, L. Afman², N. van Riel¹

1: Dept. of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; 2: Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands

5:00pm - 5:12pm
ID: 148 / 3.7: 1

MODELLING THE NEUROPROTECTIVE EFFECTS OF EXERCISE ON THE CEREBRAL VASCULATURE OVER A LIFETIME

S. Payne^1,2

1: University of Bristol, United Kingdom; 2: National Taiwan University, Taiwan

5:12pm - 5:24pm
ID: 309 / 3.7: 2

BLOOD FLOW IN INTERNAL CAROTID AS A SURROGATE OF CEREBRAL BLOOD FLOW: PHANTOM AND IN-SILICO MODEL

B. Frackowiak, S. Shulepov, M. Baragona, A. Immink, J. Muehlsteff

Philips, Netherlands, The

5:24pm - 5:36pm
ID: 495 / 3.7: 3

MULTISCALE MAPPING OF BRAIN DEVELOPMENT BY INTEGRTING DIFFUSION MRI AND HISTOLOGY

L. Xu

Cardiff University, United Kingdom

5:36pm - 5:48pm
ID: 501 / 3.7: 4

A SYSTEMATIC IN VITRO–IN SILICO EVALUATION OF INTRA-ARTERIAL THROMBOLYSIS EFFICACY IN MEVOS

A. Lucchetti¹, I. Mager¹, C. S. Weyland², O. Nikoubashman³, E. Alapais³, J. C. Clauser¹, M. Neidlin¹

1: Cardiovascular Engineering, Applied Medical Engineering, Medical Faculty, RWTH Aachen, Germany; 2: Department of Diagnostic and Interventional Neuroradiology, University Hospital Aachen, Germany; 3: Department of Diagnostic and Interventional Neuroradiology, University Hospital OWL Bielefeld, Germany

5:48pm - 6:00pm
ID: 590 / 3.7: 5

MULTISCALE MODELING AND HIGH-ORDER NUMERICAL SIMULATION OF BRAIN ELECTROPHYSIOLOGY

S. Pagani, C. B. Leimer Saglio, F. Daniele, M. Corti, N. Kumar, P. F. Antonietti

MOX-Dipartimento di Matematica, Politecnico di Milano, Italy