Veranstaltungsprogramm

B cell immunity in atherosclerosis

Christoph Binder

Medical University of Vienna, Austria

Understand Genetics – Nomenklatur und neue Gene bei schwerer HTG

Winfried März

Synlab Holding Deutschland GmbH, Mannheim

Save the Pancreas – interdisziplinäres Management von HTG-Pankreatitiden

Ahmed Madisch

Centrum Gastroenterologie Bethanien, Frankfurt a.M.

Prevent Pancreatitis – aus der Sicht des Lipidologen

Ulrich Laufs

Universitätsklinikum Leipzig

Phänotypologie und Klassifizierungsscores

Oliver Weingärtner

Universitätsklinikum Jena

Polygenic risk score - pro (therapieweisend)

Winfried März

Synlab Holding Deutschland GmbH, Mannheim

Polygenic risk score - against (noch ein weiterer score?)

Wolfgang Koenig

Deutsches Herzzentrum München

Lp(a) in der kardiovask. Risikostratifizierung …in der Klinik

Ulrike Schatz

Universitätsklinikum Dresden

Lp(a) in der kardiovask. Risikostratifizierung …in der Niederlassung

Jens Ringel

DIAMEDIKUM Potsdam

Intervallfasten und Herzinsuffizienz

Jochen Dutzmann

Universitätsklinikum Halle (Saale)

Sport, aber wie(viel)?

Ulrich Laufs

Universitätsklinikum Leipzig

Ess‘ ich‘s oder lass ich‘s lieber sein?

Stefan Lorkowski

Friedrich-Schiller-Universität Jena

Adjustment of the SMART risk score by bioactive adrenomedullin enables a more accurate prediction of mortality in patients with ASCVD

Berkan Kurt¹, Matthias Rau¹, Oliver Hartmann², Fábia Daniela Lobo de Sá², Julia Möllmann¹, Jens Spießhöfer³, Andrea Milzi¹, Jennifer Wipperfürth⁴, Edgar Dahl⁴, Nikolaus Marx¹, Michael Lehrke¹, Florian Kahles¹

1: Med. Klinik I - Kardiologie, Angiologie und Internistische Intensivmedizin, Uniklinik RWTH Aachen, Aachen; 2: Sphingotec GmbH, Hennigsdorf; 3: Med. Klinik V - Klinik für Pneumologie und Internistische Intensivmedizin, Uniklinik RWTH Aachen, Aachen; 4: RWTH cBMB am Institut für Pathologie, Uniklinik RWTH Aachen, Aachen

Association between BMI and cause-specific long-term mortality in acute myocardial infarction patients.

Timo Schmitz¹, Dennis Freuer¹, Philip Raake², Jakob Linseisen¹, Christa Meisinger¹

1: Epidemiology, Medical Faculty, University of Augsburg, Augsburg, Germany; 2: University Hospital Augsburg, Department of Cardiology, Respiratory Medicine and Intensive Care, Augsburg, Germany

ChemR23 expression protects against smooth muscle cell phenotype switching in atherosclerosis

Bryce Ridley Evans^1,2,3, Manovriti Thakur^1,2, Anais Yerly^1,2,3, Julia Schulz^1,2,3,4, Berenice Martínez-Salazar^1,2, Nico Angliker¹, Mark Siegrist¹, Yvonne Jansen⁵, Christian Weber^5,7,8, Sarah Maike Bernhard^1,2, Drosos Kotelis^2,4, Marc Schindewolf^1,2, Emiel van der Vorst^5,6,8,, Yvonne Döring^1,2,6,8

1: Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Switzerland; 2: Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland; 3: 3Graduate School for Cellular and Biomedical Sciences, University of Bern, Switzerland; 4: Department of Vascular Surgery, University Hospital Bern, 3010 Bern, Switzerland; 5: Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), 80336 Munich, Germany; 6: Institute for Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Aachen, Germany; 7: Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; 8: DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, 80336 Munich, Germany

Comprehensive and parallel analysis of different cardiovascular diseases using CITE-sequencing

Christin Elster¹, Alexander Lang¹, Miriam Ommer-Bläsius¹, Marius Böttenberg¹, Sarah Verheyen¹, Susanne Pfeiler¹, Tobias Lautwein², Holger Winkels³, Malte Kelm¹, Norbert Gerdes¹

1: Division for Cardiology, Pulmonology and Vascular Medicine, Medical Faculty and University Hospital, Heinrich-Heine University, Düsseldorf, Germany; 2: Genomics and Transcriptomics Laboratory, Biologisch-Medizinisches-Forschungszentrum (BMFZ), Heinrich Heine University Düsseldorf, Germany; 3: Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

GLP-1 provides significant added value on top of the SMART risk score for prediction of cardiovascular mortality in patients with coronary artery disease: the LURIC study

Martin Reugels¹, Marcus E. Kleber², Andrea Milzi³, Jens Spiesshoefer⁴, Carolin V. Schneider⁵, Kai M. Schneider⁵, Winfried März⁶, Nikolaus Marx¹, Michael Lehrke¹, Florian Kahles¹

1: Department of Internal Medicine I - Cardiology, Angiology and Internal Intensive Care Medicine, University Hospital RWTH Aachen, Aachen, Germany; 2: Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; 3: Cardiovascular Department, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale (EOC), Università della Svizzera Italiana, Lugano, Switzerland; 4: Pneumology and Intensive Care Medicine Department, University Hospital RWTH Aachen, Aachen, Germany; 5: Department of Medicine III - Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany; 6: SYNLAB Holding Deutschland GmbH, SYNLAB Academy, Mannheim, Germany

Gut immune cells are upregulated in heart failure and aggravate left ventricular dysfunction in mice

Maximilian Neuhaus¹, Nadim Tabaza¹, Naresh Ganesh¹, Luis Quintana¹, Maximilian Sausen¹, Maria C. Arrivas¹, Carolin V. Schneider¹, Susanne Just¹, Berkan Kurt¹, Jens Spiesshoefer¹, Kai Markus Schneider¹, Angela Schippers¹, Holger Winkels², Norbert Wagner¹, Michael Lehrke¹, Nikolaus Marx¹, Florian Kahles¹

1: Uniklinik RWTH Aachen, Aachen, Deutschland; 2: Uniklinik Köln, Köln, Deutschland

Loss of B cell-ACKR3 reduces atherosclerosis by decreasing plasma cells and pro-inflammatory antibody production

Anais Yerly^1,2, Yvonne Jansen³, Maria Berenice Martinez Salazar^1,2, Bryce Evans^1,2, Manivriti Thakur^1,2, Nico Angliker^1,2, Julia Schulz^1,2, Mark Siegrist^1,2, Sarah Maike Bernhard⁴, Drosos Kotelis⁴, Marc Schindewolf⁴, Yvonne Döring^1,2,3

1: Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital , Switzerland; 2: DBMR affiliation Department for BioMedical Research, University of Bern, Switzerland; 3: Institute of Cardiovascular Prevention, Department of Medicine, Ludwig-Maximilians-University Munich , Munich, Germany; 4: Division of vascular surgery, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, Switzerland

Macrophage expressed CD36 promotes plaque vulnerability in atherosclerosis

Mark Colin Gissler¹, Timothy Mwinyella¹, Hauke Horstmann¹, Clement Cochain², Michal Mokry³, Alexander Maier¹, Timoteo Marchini¹, Dirk Westermann¹, Dennis Wolf¹

1: University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany; 2: Institute of Experimental Biomedicine, University Hospital Wuerzburg, Wuerzburg, Germany; 3: Central Diagnostic Laboratory, University Medical Center Utrecht, Utrecht, Netherlands

Reversibility of Cardiovascular Impacts in Celiac Disease: Insights from a Gluten-Free Diet Intervention Study

Karin Keppeler¹, Aline Pesi², Simon Lange¹, Johanna Helmstädter¹, Lea Strohm¹, Henning Ubbens¹, Marin Kuntic¹, Ivana Kuntic¹, Dominika Mihalikova¹, Ksenija Vujacic-Mirski¹, Alexandra Rosenberger¹, Leonie Küster¹, Charlotte Frank², Matthias Oelze¹, Stefanie Finger^3,4, Agnieszka Zakrzewska⁵, Elena Verdu⁶, Johannes Wild^1,3,4, Susanne Karbach^1,3,4, Philip Wenzel^1,3,4, Philipp Wild^1,4, David Leistner^4,7, Thomas Münzel^1,4, Andreas Daiber^1,4, Detlef Schuppan^2,8, Sebastian Steven^1,3,7

1: Center for Cardiolog, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany; 2: Institute of Translational Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany; 3: Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany; 4: German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz/Frankfurt a. M., Germany; 5: Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland; 6: Farncombe Digestive Disease Center, McMaster University, Hamilton, Canada; 7: Division of Cardiology, Goethe University Frankfurt, University Hospital, Department of Medicine III, Germany; 8: Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

Senolytics reduce inflammation and neutrophil migration in pre-diabetic murine hearts

Ashley-Jane Duplessis¹, Camila Zöhner¹, Tobias Lautwein², Susanne Pfeiler¹, Anja Stefanski², Malte Kelm¹, Norbert Gerdes¹, Alexander Lang¹

1: Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty and University Hospital, Heinrich-Heine University, Düsseldorf, Germany; 2: BMFZ, Heinrich-Heine Universität, Düsseldorf, Deutschland

The role of ChemR23 in the bidirectional crosstalk between perivascular adipose tissue and arterial vasculature in atherosclerosis

Julia Schulz^1,2, Bryce Evans^1,3, Anaïs Yerly^1,3, Manovriti Thakur^1,3, Nico Angliker^1,3, Mark Siegrist^1,3, Emiel van der Vorst⁴, Yvonne Jansen⁵, Marc Schindewolf³, Alexander Bartelt^5,6, Drosos Kotelis², Yvonne Döring^1,3,5,6

1: Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland; 2: Department of Vascular Surgery, Inselspital, Bern University Hospital, Bern, Switzerland; 3: Department of Angiology, Inselspital, Bern University Hospital, Bern, Switzerland; 4: Institute for Molecular Cardiovascular Research (IMCAR), RWTH University Hospital Aachen, Aachen, Germany; 5: Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), Munich, Germany; 6: DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany

Erkenntnisse zur Bempedoinsäure: Ergebnisse aus den Subgruppenanalysen

Ksenija Stach

Universitätsklinikum Mannheim

hsCRP oder LDL-C Senkung - Neue Targets oder Altbewährtes?

Ingo Hilgendorf

Universitätsklinikum Freiburg

HDL - zuviel des Guten?

Arnold von Eckardstein

Universität Zürich, Schweiz

Triglyzeridreiche Lipoproteine (TRL): Klinische Bedeutung und therapeutische Konsequenzen

Martin Merkel

Endokrinologikum Hamburg

Die Heterogenität des Stoffwechsels vom Prädiabetes bis zum Diabetes

Robert Wagner

Deutsches Diabetes-Zentrum, Düsseldorf

EAS-Konsensus: Was ist neu? Was ist wichtig?

Klaus G. Parhofer

Klinikum der Universität München

Neue Studien & Fallbesprechung

Anja Vogt

LMU, Medizinische Klinik IV, München

CHIP - Impact on Cardiovascular Disease

Moritz von Scheidt

Deutsches Herzzentrum München

Age-associated immunity in atherosclerosis

Amanda Foks

Leiden University, Niederlande

Organ crosstalk in cardiovascular disease - Lecture Schönheimer Medal DGAF

Nikolaus Marx

Universitätsklinikum Aachen

Bewusstsein schaffen für eine intensive, frühe und langanhaltende Lipidtherapie.

Daniel Sedding

Universitätsklinikum Halle (Saale)

Lower, Earlier, Longer - Von der Plaque Modulation, über Stabilisierung bis hin zur Regression.

Wolfgang Koenig

Deutsches Herzzentrum München

Proteomics Strategies to Identify New Diagnostic and Therapeutic Targets in CVD

Manuel Mayr

Imperial College, London, UK

Spatial atlas of Human Atherosclerosis for target discovery

Sikander Hayat

Universitätsklinikum Aachen

System biology approaches for CVD

Matthias Heinig

Helmholtz München

Diabetes

Dirk Müller-Wieland

Universitätsklinikum Aachen

Herzinsuffizienz

Daniel Sedding

Universitätsklinikum Halle (Saale)

Hypertonie

Johannes Stegbauer

Universitätsklinikum Düsseldorf

Intravaskuläre Bildgebung/precision PCI

David M. Leistner

Universitätsklinikum Frankfurt

Mikrovaskuläre Gefässanalyse

Walthard Vilser

TU Ilmenau