Interoception research, much like the visceral body it studies, waxes and wanes over the decades. One constant in this cycle is the challenge of gaining direct access to the organs involved. Unlike exteroceptive systems, shifting visceral signals in humans is difficult without crossing into invasive methods. In this talk I will outline new approaches to measuring interoception across gastric, respiratory, and cardiac domains, and highlight recent work where we test ways of intervening on these axes. To move from correlational description toward mechanism, we need interventions that are both reproducible and meaningful. I will look back at some of the earlier attempts that shaped the field, then turn to current work that shows where progress may come next.Research on interoception has long been limited by the difficulty of directly accessing visceral signals without invasive methods. In this talk, new approaches to measuring interoceptive signals across gastric, respiratory, and cardiac domains are presented.