Conference Agenda
Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
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Daily Overview |
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146: Advancing Biological Psychology and Neuroscience through Meta-Analytical Approaches
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Meta-analyses have become foundational tools for synthesising evidence and are receiving increasing attention across research disciplines. This symposium will present meta-analytical approaches from various fields, providing an overview of their application and demonstrating their potential as well as challenges that may arise. The symposium will bring together meta-analyses and related methods conducted by senior and early-career researchers working in various fields. Gordon Feld (Mannheim) will open the symposium with a talk presenting findings of a resampling study showing that effect sizes in small-sample fMRI studies are likely to be overestimated compared to behavioral effects. The following two talks will focus on traditional meta-analyses on aggregate data (AD-MAs). Maria Bruntsch (Bielefeld) will present a meta-analysis in the field of fear conditioning investigating how anxiety-related traits (e.g. trait anxiety, neuroticism and intolerance of uncertainty) may influence fear learning processes. Laura Klatt (Nijmegen) will report findings from a meta-analysis of the lateralization of cortical alpha rhythms in response to spatial cuing to investigate how experimental manipulation modulates brain activity. Julian Packheiser (Bochum) will give the last talk, focusing on individual participant data meta-analysis (IPD-MA) in health psychology, highlighting the necessity of conducting IPD-MAs. The symposium will conclude with a moderated discussion on the role of meta-analyses in psychological and neuroscientific research, focusing on their methodological implications, strengths, and limitations. | ||
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Mass Univariate Testing Inflates Effect Sizes in fMRI Central Institute of Mental Health, Germany Kommt noch Meta-Analytical Investigation of the Association Between Anxiety-Related Traits and Fear Learning Processes 1Universität Bielefeld, Germany; 2University Medical Center Hamburg-Eppendorf, Germany; 3University of Texas at Austin, USA; 4Reichman University, Israel; 5Philipps-Universität Marburg, Germany; 6KU Leuven, Belgium; 7American College of Thessaloniki, Greece; 8City University of New York, USA; 9University of Southampton, UK; 10University College Dublin, Ireland Altered processing of fear and safety learning has been linked to individual differences of anxiety symptoms and anxiety-related personality traits, such as neuroticism, intolerance of uncertainty, and negative emotionality. However, the literature is limited by individual studies focusing on different aspects of fear conditioning and extinction, using varying outcome measures, and assessing different anxiety-related traits, mostly in isolation. This heterogeneity poses a challenge to cumulative knowledge building on g the overall relationship between anxiety-related traits and fear learning processes. To bridge this gap, a comprehensive systematic review and meta-analysis (Registered Report) was performed, examining how anxiety-related traits relate to fear acquisition and extinction. Following a thorough screening of titles, abstracts, and full texts, over 90 studies were included in the final analysis. Additionally, an item-level content analysis was conducted on the questionnaires used to assess anxiety-related traits in the included studies (n = 28) to also evaluate the conceptual overlap among these constructs. The presentation will share preliminary findings from both analyses, discuss their implications for the field of research and highlight directions for future research in this field. Alpha Lateralization: A Meta-Analytic Test Case For What We Can Know About The Link Between Cognition and Oscillatory Brain Activity 1Donders Institute for Brain, Cognition and Behavior, Radboud University, The Netherlands; 2Institute for Medical Psychology, Goethe University Frankfurt, Frankfurt, Germany; 3Université de Toulouse III Paul Sabatier, Toulouse, France; Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Cerveau et Cognition (CerCo), UMR 5549, Toulouse, France; 4University of Dundee, Psychology, DD1 4HN Nethergate, Dundee, UK; 5University of Stirling, Psychology, FK9 4LA Stirling, UK; 6Wilhelm Wundt Institute for Psychology, University of Leipzig, Leipzig, Germany; 7Otto-von-Guericke University Magdeburg, Magdeburg, Germany; 8University of Lancashire, Preston, Lancashire, UK; 9Basque Center on Cognition, Brain and Language, Universitat Politècnica de Catalunya, Barcelona, Spain; 10Department of Psychology, University of Lübeck, Germany; 11Department of Psychology, University of Southern Denmark, Denmark; 12School of Psychology, University of Aberdeen, UK Quantifying the strength of the relationships between brain rhythms and cognition remains a core interest in cognitive neuroscience. Yet, despite a long-standing emphasis on reporting and interpreting effect sizes, reflected in journal guidelines and publication manuals, the field is still overly focused on statistical significance. In this large-scale proof-of-concept study, we aim to provide a comprehensive meta-analytic assessment of the landscape of effect sizes and reporting standards, using the established effect of attentional modulations of alpha power. We identified 4601 records, out of which 200 passed the abstract and full-text screening stage. Out of those 200 studies, only 46% provided sufficient information to either extract or compute a measure of effect size for alpha power lateralization. The primary reasons for missing effect sizes were the use of cluster-based permutation tests (52%), incomplete reporting of statistical parameters (35%), and the lack of appropriate tests against zero (13%). A descriptive analysis of the dataset reveals that most studies investigated anticipatory, endogenous shifts of attention in the visual domain, whereas other timescales of attention (e.g., retro-active shifts of attention), exogenous cuing, or other modalities (e.g., auditory/tactile) are less frequently targeted. A preliminary meta-analysis of 92 studies revealed a medium-sized effect. The data also show clear signs of significant funnel plot asymmetry. Ongoing analyses aim at assessing how effect sizes differ for a range of potential moderators, such as sensory modality, cue validity or target eccentricity. Implications for reporting standards in the field will be discussed. Beyond Aggregation: Practical Challenges and Methodological Decisions in Individual Participant Data Meta-Analyses 1Department of Social Neuroscience, Center of Medical Psychology and Translational Neurosciences, Medical Faculty, Ruhr University Bochum, Bochum, Germany; 2Research Center One Health Ruhr of the University Alliance Ruhr, Ruhr University Bochum, Germany Individual participant data (IPD) meta-analyses are increasingly regarded as a gold standard for evidence synthesis, offering substantial advantages over traditional aggregate-data approaches. However, these benefits come at the cost of considerable practical and methodological complexity. In this talk, I will use an ongoing IPD meta-analysis as a case example to illustrate key challenges and decision points in conducting IPD meta-analyses. The presentation will focus on the full workflow, from initial data acquisition to statistical modeling. First, I will discuss challenges related to data collection, including study identification, data requests, and common barriers to data sharing, such as legal and ethical constraints. Second, I will address issues of data harmonization, including the alignment of heterogeneous measures, handling of missing data, and ensuring comparability across studies. Third, I will outline key analytical decisions, with a particular focus on the comparison between one-stage and two-stage modeling approaches and their implications for inference. The talk aims to provide a transparent account of the practical realities of IPD meta-analyses, highlighting common pitfalls and strategies to address them. By doing so, it seeks to contribute to ongoing discussions on best practices and to support researchers considering IPD approaches in their own work. | ||
