Since the mid-2000s, large-scale investments in agriculture have increased sharply in developing countries, driven by rising commodity prices, strategic concerns of food-importing countries, and commercial opportunities. In Tanzania, there are a growing number of large-scale agricultural investments by the private sector, often involving the acquisition of large tracts of land. While such investments are frequently carried out for the means of improving food security and reducing poverty, they are often implicated in contributing to farmland encroachment and displacement of rural people, exacerbating food insecurity and poverty among women as small-scale food producers. This Master Class provides recommendations on how the Responsible Investments in Property and Land (RIPL) Guidebooks can be utilized to guide land-based investments in Tanzania to better ensure that women meaningfully participate and benefit from such investments. The RIPL Guidebooks offer valuable information for governments, investors and civil society groups in regard to designing policies and practices.