Conference Agenda

4:15pm - 4:40pm

ANGIOTENSIN II REGULATES KV7 CHANNELS IN CENTRAL NEURONS AND BRAIN ENDOTHELIAL CELLS

Camilla Celentano¹, Stafania Iervolino¹, Giovanni Schipani¹, Rossella Vitale¹, Flavia De Martino¹, Giusy Carleo¹, Marialuisa Perrotta^2,3, Daniela Carnevale^2,4, Francesco Miceli¹, Maurizio Taglialatela¹, Vincenzo Barrese¹

¹Dept Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Italy; ²Department of Angiocardioneurology and Translational Medicine, IRCCS Neuromed, Pozzilli (IS), Italy; ³Department of Molecular Medicine, "Sapienza" University of Rome, Rome, Italy; ⁴Department of Medical and Surgical Sciences and Biotechnologies, Polo Pontino, 'Sapienza' University of Rome, Rome, Italy

4:40pm - 5:05pm

GLIAL KCNQ CHANNELS REGULATE NEURONAL EXCITABILITY VIA GLIAL GABA RELEASE

Bianca Graziano, Lei Wang, Olivia R. White, Daryn H. Kaplan, Jesus Fernandez-Abascal, Antonella Mini, Tylor M. Pohl, Brianna N. Carney, Roberta Brambilla, Laura Bianchi

University of Miami, United States of America

5:05pm - 5:30pm

KV7.2 IS THE PRINCIPAL M-TYPE K+ CHANNEL SUBUNIT MODULATING PAIN BEHAVIOURS IN RATS.

Frederick Jones^1,2, Shihab Shah¹, Stephen W. Milne¹, Pierce Mullen¹, Baolin Li³, Emanuele Sher⁴, Nikita Gamper¹

¹Faculty of Biological Sciences, University of Leeds, United Kingdom; ²Department of Life Sciences, Manchester Metropolitan University, United Kingdom; ³Neuroscience Discovery, Eli Lilly and Company, Indiana; ⁴Lilly UK Neuroscience Hub, Eli Lilly and Company, United Kingdom

5:30pm - 5:55pm

KV7.2 CHANNELS SHAPE EXCITABILITY AND SALTATORY CONDUCTION AT THE NODE OF RANVIER IN HEAVILY MYELINATED NERVES

Sotatsu Tonomura, Jennifer Ling, Jianguo Gu

The University of Alabama at Birmingham, United States of America

5:55pm - 6:05pm

PHARMACOLOGICAL ACTIVATION OF KCNQ4 SUPPRESSES PERIPHERAL NOCICEPTIVE SIGNALING IN MICE

Long Wang^1,4, Man Xu^1,2, Demin Ma³, Zhiyong Gu^1,4, Haiyan Xu^1,4, Fajun Nan^1,2, Jiangtao Guo³, Zhaobing Gao^1,2,4

¹State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; ²College of Pharmacy, University of Chinese Academy of Sciences, Beijing 100049, China; ³Department of Biophysics and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China; ⁴Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China