Conference Agenda

Poster session abstracts

Radomír Kužel

Hundreds of starting points for spliceosomal PPI modulators identified by crystallographic fragment screening with the F2X-Universal Library

Tatjana Barthel^1,3, Jan Wollenhaupt¹, Gustavo M. A. Lima², Markus C. Wahl³, Manfred S. Weiss¹

¹Helmholtz-Zentrum Berlin, Macromolecular Crystallography, Albert-Einstein-Str. 15, 12489 Berlin, Germany; ²MAX IV Laboratory, BioMAX, Fotongatan 2, 224 84 Lund, Sweden; ³Freie Universität Berlin, Institute of Chemistry and Biochemistry, Laboratory of Structural Biochemistry, Takustraße 6, 14195 Berlin, Germany

HIF-Prolyl-Hydroxylase 2 Clinical Inhibitor Complex Structure and XChem Fragment-Based Screen Obtained with Succinate Co-Product Used as a Crystallisation Tool.

William D. Figg Jr¹, Michael A. McDonough¹, Yu Nakashima^1,3, Rasheduzzaman Chowdhury^1,2, Christopher J. Schofield¹

¹Department of Chemistry, University of Oxford, Oxford, United Kingdom; ²Cardiovascular Research Institute, University of California, San Fransciso, CA, United States; ³Institute of Natural Medicine, University of Toyama, Toyama, Japan

Updates from FragMAX, a crystallographic fragment screening platform at MAX IV Laboratory

Tobias Krojer

MAX IV Laboratory, Lund University, PO Box 118, S-221 00 Lund, Sweden