Conference Agenda

Session
MS-92 (34b): Structural biology of enzymes, mechanism and regulation II
Time:
Saturday, 21/Aug/2021:
10:20am - 12:45pm

Session Chair: Mirjam Czjzek
 Location: Club A

170 1st floor

Session Abstract

How does crystallography provide understanding of enzymes. This topic could also include recent advances in the area of time resolved crystallography.

For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction of M S-34, or individual abstracts below.


Presentations
10:20am - 10:50am

Structural insights into the transposition of antibiotic resistance

Georgy Smyshlyaev1,2,3, Buse Isbilir1,2, Carlos Rojas-Cordova1,2, Anna Rubio-Cosials1, Lotte Lambertsen1, Alex Bateman3, Orsolya Barabas1,2

1University of Geneva, Geneva, Switzerland; 2Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany; 3European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK

External Resource: https://www.xray.cz/iucrv/vidp.asp?id=621

10:50am - 11:20am

Extraordinary Structures of Orphan Methyltransferases with Their Substrate DNA

John Horton, Jujun Zhou, Clayton Woodcock, Xing Zhang, Xiaodong Cheng

Department of Epigenetics and Molecular Carcinogenesis, The University of Texas -M.D. Anderson Cancer Center, Houston TX, USA

External Resource: https://www.xray.cz/iucrv/vidp.asp?id=622

11:20am - 11:40am

Structural and mechanistic basis for protein glutamylation by the kinase fold

Diana R. Tomchick1, Miles H. Black1, Adam Osinski1, Krzysztof Pawłowski2, Marcin Gradowski2, Zhe Chen1, Yang Li1, Kelly A. Servage1, Vincent S. Tagliabracci1

1UT Southwestern Medical Center, Dallas, United States of America; 2Warsaw University of Life Sciences, Warsaw, Poland

External Resource: https://www.xray.cz/iucrv/vidp.asp?id=623

11:40am - 12:00pm

Mechanism of RNA stimulated ATP hydrolysis by tick-borne encephalitis virus NS3 helicase

Paulina Duhita Anindita, Pavel Grinkevich, Marco Halbeisen, Roman Tuma, Zdenek Franta

Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic

External Resource: https://www.xray.cz/iucrv/vidp.asp?id=624

12:00pm - 12:20pm

Quinol-dependent Nitric Oxide Reductases are dimers in cryoEM structures

Samar Hasnain

University of Liverpool, Liverpool, United Kingdom

External Resource: https://www.xray.cz/iucrv/vidp.asp?id=625

12:20pm - 12:40pm

Interactive GUI for the calculation of Fobs-Fobs electron density difference maps and extrapolated structure factors based on the cctbx toolbox

Elke De Zitter1, Nicolas Coquelle2, Thomas Barends3, Jacques-Philippe Colletier1

1Institut de Biologie Structurale, Université de Grenoble Alpes, CEA, CNRS, 38044 Grenoble, France; 2Institut Laue-Langevin, 38044 Grenoble, France; 3Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, 69120 Heidelberg, Germany

External Resource: https://www.xray.cz/iucrv/vidp.asp?id=626