| Session | ||
MS-81: Nucleic acids and binding proteins structure and function
Invited: Millie Georgiadis (USA), Liliya Yatsunyk (USA) | ||
| Session Abstract | ||
|
Structural biology is particularly sucessful in elucidating how proteins recognize nucleic acids in various physiological process from decoding genetic information, maintenance of the genome, through RNA turnover to name a few. Recent advancements in the field will be presented in this session. | ||
| Presentations | ||
2:45pm - 2:50pm
Introduction to session 2:50pm - 3:20pm
Non-canonical DNA structures and their interactions with small molecule ligands Swarthmore College, 500 College Ave, Swarthmore, PA, United States of America External Resource: https://www.xray.cz/iucrv/vidp.asp?id=564
3:20pm - 3:50pm
Structural properties of Alien DNA, an alternative genetic system 1Indiana University School of Medicine, Indianapolis, Indiana, United States of America; 2Foundation for Applied Molecular Evolution, Alachua, Florida, United States of America External Resource: https://www.xray.cz/iucrv/vidp.asp?id=565
3:50pm - 4:10pm
APE1 Exonuclease Distinguishes Various DNA Substrates by an Induced Space-Filling Mechanism. 1Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan; 2Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu 30068, Taiwan; 3Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 4Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30068, Taiwan External Resource: https://www.xray.cz/iucrv/vidp.asp?id=566
4:10pm - 4:30pm
Structural characterization of clinically reported missense mutations identified in BRCA1 Tata Memorial Centre Advanced Centre for Treatment, Research and Education in Cancer, Mumbai, India External Resource: https://www.xray.cz/iucrv/vidp.asp?id=567
4:30pm - 4:50pm
Solid-solid phase transition in adenine riboswitch crystals driven by large conformational changes induced by ligand 1Center for Structural Biology, Centre for Cancer Research, National Cancer Institute, Frederick, MD-21702, USA.; 2Optical Microscopy and Analysis Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.; 3X-ray Science Division, Argonne National Laboratory, Lemont, IL 60439, USA External Resource: https://www.xray.cz/iucrv/vidp.asp?id=568
Molecular mechanism of self-antigen recognition by the ligand binding domain of B cell inhibitory co-receptor CD72 1Department of Structural Biology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan; 2RIKEN SPring-8 Center, Hyogo, Japan; 3Department of Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan External Resource: https://www.xray.cz/iucrv/vidp.asp?id=569
| ||