Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

Please note that all times are shown in the time zone of the conference. The current conference time is: 26th Nov 2022, 02:01:49pm CET

 
 
Session Overview
Session
MS-33: CryoEM for macromolecules - from single particles to microcrystals
Time:
Tuesday, 17/Aug/2021:
10:20am - 12:45pm

Session Chair: Jan Pieter Abrahams
Session Chair: Jiri Novacek
Location: Club A

170 1st floor

Invited:  Nenad Ban (Switzerland), Dimple Karia (Netherlands)


Session Abstract

Cryogenic electron microscopy (cryo-EM) rivals X-ray crystallography in terms of resolution and can be used to determine atomic structures of macromolecules that are either refractory to crystallization or difficult to crystallize in specific functional states. Electron diffraction can yield structures of proteins even when crystals are smaller than the wavelength of light. The session focuses on examples of both methods.  We encourage people working on both single particle cryo-EM of biological macromolecules and electron diffractions of microcrystals to submit their abstract and to attend the Microsymposium entitled “Cryo-EM for macromolecules – from single particles to microcrystals”.


For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction, or individual abstracts below.

 


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Presentations
10:20am - 10:25am

Introduction to session

Jan Pieter Abrahams, Jiří Nováček



10:25am - 10:55am

Structural basis of SARS-CoV-2 translational shutdown and programmed ribosomal frameshifting

Nenad Ban

ETH Zurich, Zurich, Switzerland



10:55am - 11:25am

Home source for cryo-EM

Dimple Karia1, Adrian Koh1, Zuzana Hlavenkova2, Milos Malinsky2, Vojtech Dolezal2, Alevtyna Yakushevska1, Lingbo Yu1, Abhay Kotecha1

1Thermo Fisher Scientific, Materials and Structural Analysis Division, Achtseweg Noord, Eindhoven, Netherlands; 2Thermo Fisher Scientific Brno s.r.o, Materials & Structural Analysis, Brno, Czech Republic



11:25am - 11:50am

High-resolution structures of immature and chimeric flaviviruses reveal key features redefining viral architecture and maturation

Joshua Hardy1, Natalee Newton2, Naphak Modhiran2, Connor Scott2, Hari Venugopal1, Laura Vet2, Paul Young2, Roy Hall2, Jody Hobson-Peters2, Daniel Watterson2, Fasseli Coulibaly1

1Monash University, Clayton, VIC, Australia; 2The University of Queensland, Brisbane, QLD, Australia



11:50am - 12:15pm

Receptor induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating

Dominik Hrebík, Tibor Füzik, Mária Gondová, Lenka Šmerdová, Athanassios Adamopoulos, Ondrej Šedo, Zbyněk Zdráhal, Pavel Plevka

CEITEC MU, Brno, Czech Republic



12:15pm - 12:40pm

M. tuberculosis enolase: Crystal and Cryo-EM structures provide insights into 2-phosphoglycerate binding and catalysis

Mohammed Ahmad1, Bhavya Jha1, Sucharita Bose2, Satish Tiwari1, Abhisek Dwivedy1, Richard Mariadasse3, Ravikant Pal1, Tanya Parish4, J jayekanthan3, Vinothkumar kutti Ragunath2, Bichitra Kumar Biswal1

1National Institute of Immunology, New Delhi, India; 2National Centre for Biological Sciences, Bangalore 560065, India; 3Alagappa University ,Karaikudi, Tamil Nadu 630003, India; 4Infectious Disease Research Institute, 1616 Eastlake Avenue E, Suite 400, Seattle,WA98102, United States



 
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