ID: 1968
/ Poster - 41 Receptors: 1
Poster session abstracts
Poster
Poster session abstracts
Radomír Kužel
ID: 709
/ Poster - 41 Receptors: 2
Bursary application
Oral/poster
MS: Structural biology of receptors, signaling and membrane proteinsPosters only: Macromolecular and biological crystallography (if it does not fit to any specific topics)Keywords: RTKs; crystal structure; secondary structural changes; mutations; cancer; change in intramolecular interactions
Structural anomalies in the Eph receptor due to clinically relevant mutations and the subsequent effect on kinase domain
Shubhashish Chakraborty1,2, Ashok Kumar Varma1,2
1Advanced centre for Treatment, Research and Education in cancer, Kharghar, Navi Mumbai, Maharashtra – 410210,INDIA; 2Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra – 400094 ,INDIA.
Bibliography Comparative structural analysis of clinically relevant cancer mutations reported in EphA7 receptor tyrosine kinase*.
*Manuscript in process.
ID: 998
/ Poster - 41 Receptors: 3
Biological and macromolecular crystallography
Poster
MS: Structural biology of receptors, signaling and membrane proteinsKeywords: NK cell; NKp30; B7-H6; glycosylation; oligomerization
Influence of glycosylation on the structure of human natural killer cell receptor NKp30 in complex with its tumor ligand B7-H6
Tereza Skalova1, Ondřej Skořepa2, Barbora Kalousková2, Jan Bláha2, Celeste Abreu2, Jan Dohnálek1, Ondrej Vaněk2
1Institute of Biotechnology CAS, v.v.i., Vestec, Czech Republic; 2Department of Biochemistry, Faculty of Science, Charles University Prague, Hlavova 8, 128 40 Praha, Czech Republic
ID: 1467
/ Poster - 41 Receptors: 4
Biological and macromolecular crystallography
Poster
MS: Structural bioinformatics, Structural biology of eukaryotic immune systems, Structural biology of receptors, signaling and membrane proteinsPosters only: Macromolecular and biological crystallography (if it does not fit to any specific topics)Keywords: TCR repertoire, cholesterol-dependent cytolysins, T cell epitopes, pneumolysin
CD4+ T cell recognition of pneumolysin, a pore-forming cytolysin derived from Streptococcus pneumoniae presented by a common HLA allotype
Lisa Ciacchi1, Martijn D. B. van de Garde2, Jan Petersen1, Carine Farenc1, Martien C. M. Poelen2, Hugh H. Reid1, Kristin Ladell3, David A. Price3, Cecile A. C. M. van Els2, Jamie Rossjohn1
1Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia; 2Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands; 3Cardiff University School of Medicine, Cardiff, United Kingdom
ID: 1627
/ Poster - 41 Receptors: 5
Biological and macromolecular crystallography
Poster
MS: Structural biology of receptors, signaling and membrane proteinsKeywords: CD160/BY55; HVEM/TNFRSF14; immune receptor; immunological synapse; receptor-ligand interaction
Molecular characterization of the native (non-linked) CD160-HVEM protein complex revealed by initial crystallographic analysis
Simona Lenhartová1, Marek Nemčovič2, Radka Šebová1, Mário Benko1, Dirk Zajonc3,4, Ivana Nemčovičová1
1Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovak Republic; 2Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia; 3Division of Immune Regulation, La Jolla Institute for Immunology, La Jolla, CA, USA; 4Cancer Immunology Discovery, Pfizer Inc., San Diego, CA, USA
ID: 1534
/ Poster - 41 Receptors: 6
Biological and macromolecular crystallography
Oral/poster
MS: Structural biology of receptors, signaling and membrane proteins, Structure guided drug design and antibiotic resistance targetsKeywords: X-ray, Cryo-EM, drug design, membrane proteins
Structure-based drug discovery enabled for membrane protein targets
Michael Hennig
leadXpro AG, Villigen, Switzerland
ID: 1453
/ Poster - 41 Receptors: 7
Biological and macromolecular crystallography
Poster
MS: Structural biology of receptors, signaling and membrane proteins, Protein design and engineeringPosters only: Macromolecular and biological crystallography (if it does not fit to any specific topics)Keywords: antibody labeling, epitope insertion, antibody-assisted structural analysis, electron microscopy, protein crystallography
Optimization of the NZ-1 labeling technique for the application to 3D structure analysis
Rie Aruga1, Risako Tamura-Sakaguchi1, Mika Hirose2, Toru Ekimoto1, Rika Oi1, Mika K. Kaneko3, Yukinari Kato3,4, Mitsunori Ikeguchi1,5, Kenji Iwasaki6, Terukazu Nogi1
1Graduated School of Medical Life Science, Yokohama-city University, Japan; 2Institute for Protein Research, Osaka University, Japan; 3Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Japan; 4New Industry Creation Hatchery Center, Tohoku University, Japan; 5Center for Computational Science, RIKEN, Japan; 6Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan
ID: 1633
/ Poster - 41 Receptors: 8
Biological and macromolecular crystallography
Oral/poster
MS: Structural bioinformatics, CryoEM for macromolecules - from single particles to microcrystals, Structural biology of receptors, signaling and membrane proteins, Macromolecular machines and hybrid methods to crystallography, Structural bioinformaticsPosters only: Hot structures of biological importanceKeywords: cryoEM, bacterial toxins, phylogenetics, membrane proteins, pore-forming proteins
Structure, function and evolution of the orally active insecticidal toxin complex, YenTc
Sarah Piper1,2, Lou Brillault1,2, Joseph Box1, Yu Shang Low1, Irene Chassagnon1, Gabriel Foley1, Nadezhda Aleksandrova1, Lauren Hartley-Tassell4, Cassandra Pegg1, Ben Schulz1, Thomas Ve4, Shaun Lott3, Mark Hurst5, Michael Landsberg1,2
1School of Chemistry and Molecular Bioscience, The University of Queensland, St Lucia, Australia; 2Institute for Molecular Bioscience, The University of Queensland; 3School of Biological Sciences, The University of Auckland; 4Institute for Glycomics; 5AgResearch NZ
ID: 1729
/ Poster - 41 Receptors: 9
All topics
Poster
MS: Structural biology of receptors, signaling and membrane proteinsKeywords: TLR signalling pathway
Understanding the structural basis of TIR-domain assembly formation in TRAM- and TRIF- dependent TLR signalling
Mengqi Pan, Andrew Hedger, Jeff Nanson, Bostjan Kobe
the University of Queensland, St Lucia, Australia
ID: 1920
/ Poster - 41 Receptors: 10
Poster sessions
Poster
Posters only: Structural biology of receptors, membrane proteinsKeywords: Toll-like receptors, Negative-stain EM, TLR signaling
Structural basis of higher-order assembly formation in Toll-like receptors 1,2 and 6 signaling pathway
YAN LI
The University of Queensland, St Lucia, Australia
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