Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
Please note that all times are shown in the time zone of the conference. The current conference time is: 6th Dec 2022, 02:46:29am CET
Session Chair: Jose-Maria Carazo Session Chair: Elena Orlova
170 1st floor
Invited: Florence Tama (Japan), Pavel Afonine (USA), G. Kleywegt (Germany)
New achievements in Cryo-electron microscopy enabled a revolution in structural biology and over the last few years reached resolutions comparable with crystallography. Still, quantitative assessment of these structures is urgently needed, and essential for the validation of all these new EMDB and PDB entries. New algorithms tailored to the nature of these data need to be developed and made widely available to the community. This session will present the advancements in this field.
For all abstracts of the session as prepared for Acta Crystallographica see external PDF, or individual abstracts below.
10:20am - 10:50am
Protein hydrogen bond parameters as a new validation tool
Pavel Afonine1, Oleg Sobolev1, Nigel Moriarty1, Yanting Xu1,2, Thomas Terwilliger3,4, Paul Adams1,5
1Lawrence Berkeley National Laboratory, Berkeley, United States of America; 2International Center for Quantum and Molecular Structures, Shanghai University, Shanghai 200444, People's Republic of China; 3Bioscience Division, Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545, USA; 4New Mexico Consortium, Los Alamos, NM 87544, USA; 5Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA
10:50am - 11:20am
Integrative modeling to characterize structure and dynamics of biomolecules
Nagoya University & RIKEN, Nagoya, Japan
11:20am - 11:50am
Community recommendations on validating cryo-EM models and data
EMBL EBI, Cambridge, United Kingdom
11:50am - 12:05pm
Cryo-EM Validation Metrics in EMDA
Rangana Warshamanage, Keitaro Yamashita, Garib N. Murshudov
MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, Biomedical Campus, Cambridge, CB2 0QH, UK
12:05pm - 12:20pm
FSC-Q: A method for quality analysis of cryoEM-derived models
Erney Ramírez-Aportela, David Maluenda, Yunior C. Fonseca, Pablo Conesa, Roberto Marabini, Carlos Oscar S. Sorzano, Jose M. Carazo