Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

Please note that all times are shown in the time zone of the conference. The current conference time is: 26th Nov 2022, 01:05:54pm CET

Session Overview
MS-49: Protein design and engineering
Wednesday, 18/Aug/2021:
2:45pm - 5:10pm

Session Chair: Charlotte Uetrecht
Session Chair: Sheena McGowan
Location: Club A

170 1st floor

Invited: Elizabeth M.J. Gillam (Australia), Mauri Kostiainen (Finland)

Session Abstract

Protein design and engineering offers an exciting opportunity for the development of new biotechnologies, therapeutics, food security measures and basic scientific understanding. The IuCR 2020 microsymposium on protein design and engineering will feature the latest research findings from a diverse range of speakers, providing new information and opportunities for collaboration.

For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction, or individual abstracts below.

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2:45pm - 2:50pm

Introduction to session

Charlotte Uetrecht, Sheena McGowan

2:50pm - 3:20pm

Using Ancestral Sequence Reconstruction to Create Robust, Highly Expressed Proteins for Crystallography

Elizabeth M.J. Gillam1, Raine E.S. Thomson1, Stephlina A. D'Cunha1, Kurt L. Harris1, Gabriel Foley1, Mikael Boden1, Aaron G. Bart2, Emily E. Scott2

1The University of Queensland, Brisbane, Australia; 2University of Michigan, Ann Arbor, MI, Unites States

3:20pm - 3:50pm

Protein cage directed nanoparticle superlattices

Mauri Kostiainen

Aalto University, Espoo, Finland

3:50pm - 4:10pm

The bright-side and the dark-side of computational protein stabilization

Martin Marek1,2, Klara Markova1, Antonin Kunka1,2, Klaudia Chmelova1, Martin Havlasek1, Petra Babkova1,2, Sérgio Marques1,2, Michal Vasina1,2, Joan Iglesias-Planas1, Radka Chaloupkova1,2, David Bednar1,2, Zbynek Prokop1,2, Jiri Damborsky1,2

1Masaryk University, Brno, Czech Republic; 2International Clinical Research Center, St. Anne’s University Hospital Brno, Czech Republic

4:10pm - 4:30pm

Enzyme engineering by random mutagenesis: structural and functional studies of modified plant-type L-asparaginase (EcAIII)

Joanna Loch1, Agnieszka Klonecka1, Kinga Kądziołka1, Piotr Bonarek2, Jakub Barciszewski3, Krzysztof Lewiński1, Mariusz Jaskolski3,4

1Jagiellonian University, Faculty of Chemistry, Krakow, Poland; 2Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology, Krakow, Poland; 3Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland; 4Faculty of Chemistry, A. Mickiewicz University, Poznan, Poland

4:30pm - 4:50pm

Computational design of symmetric eight and nine-bladed β-propellers

Bram Mylemans, Arnout RD Voet

KU Leuven, Heverlee, Belgium

4:50pm - 5:10pm

Structural evidence for the bleaching caused by oxygen in rsCherry

Thi Yen Hang Bui1, Benjamien Moeyaert1, Ludovic Pecqueur2, Bindu Srinivasu3, Anastassios Economou3, Marc Fontecave2, Peter Dedecker1, Luc Van Meervelt1

1Biochemistry, Molecular and Structural Biology; Department of Chemistry, KU Leuven, Belgium; 2Chemistry of Biological Processes, Collège de France, Paris, France; 3Laboratory of Molecular Bacteriology, Rega Institute, KU Leuven, Belgium

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