Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

Please note that all times are shown in the time zone of the conference. The current conference time is: 6th Dec 2022, 01:59:58am CET

Session Overview
MS-41: Macromolecular machines and hybrid methods to crystallography
Wednesday, 18/Aug/2021:
10:20am - 12:45pm

Session Chair: Michael Landsberg
Session Chair: Dmitry Svergun
Location: Club B

50 1st floor

Invited: Kristina Djinovic-Carugo (Austria), Tanmay Bharat (India)

Session Abstract

Structures of molecular machines give a broad understanding of the dynamic workings of complexes in a cellular context. This topic will highlight advances made both in crystallography and cryoEM on large macromolecular complexes. The use of synchrotrons in structure determination of these large molecular machines will be highlighted.


For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction, or individual abstracts below.

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10:20am - 10:25am

Introduction to session

Michael Landsberg, Dmitry Svergun

10:25am - 10:55am

Structural biology of prokaryotic cell surfaces

Tanmay Bharat

University of Oxford, Oxford, United Kingdom

10:55am - 11:25am

Order from disorder in the sarcomere: FATZ forms a fuzzy complex and phase-separated macromolecular condensates with α-actinin


University of Vienna, Vienna, Austria

11:25am - 11:45am

Deciphering the role of unique bacterial transcription-associated factor HelD.

Tomáš Kovaľ1, Tomáš Kouba2, Petra Sudzinová3, Jiří Pospíšil3, Barbora Brezovská3, Jarmila Hnilicová3, Hana Šanderová3, Martina Janoušková3, Michaela Šiková3, Petr Halada3, Michal Sýkora4, Ivan Barvík5, Jiří Nováček6, Mária Trundová1, Jarmila Dušková1, Tereza Skálová1, URee Chon7, Katsuhiko S. Murakami7, Libor Krásný3, Jan Dohnálek1

1Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic; 2EMBL Grenoble, Grenoble, France; 3Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic; 4Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic; 5Faculty of Mathematics and Physics, Institute of Physics, Charles University, Prague, Czech Republic; 6CEITEC, Masaryk University, Brno, Czech Republic; 7The Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA, USA

11:45am - 12:05pm

Anomalous small-angle X-ray scattering on biological macromolecules at the P12 beamline of EMBL-Hamburg

Andrey Gruzinov1, Martin Schroer1, Clement Blanchet1, Karen Manalastas-Cantos1, Alexey Kikhney1, Nelly Hajizadeh1, Florian Wieland2, Florian Schulz3, Daniel Franke1, Cy Jeffries1, Dmitri Svergun1

1EMBL Hamburg c/o DESY, Notkestrasse 85, 22607 Hamburg, Germany; 2Helmholtz-Zentrum Geesthacht (Außenstelle DESY), Notkestrasse 85, 22607 Hamburg, Germany; 3University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany

12:05pm - 12:25pm

An asymmetric structure of the filament is key to inducing flagellar curvature and enabling motility in the Leptospira spirochete

Fabiana San Martin1, Kimberley H Gibson2, Felipe Trajtenberg1, Megan R Brady2, Elsio A Wunder3, Mathieu Picardeau4, Ariel Mechaly1, Albert I Ko3, Charles V Sindelar2, Alejandro Buschiazzo1

1Lab of Molecular & Structural Microbiology, Institut Pasteur de Montevideo, Mataojo 2020, Montevideo, Uruguay; 2Dept of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, USA; 3Dept of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, USA; 4Biology of Spirochetes Unit, Institut Pasteur, Paris, France

12:25pm - 12:45pm

Structure of the 80S ribosome from Candida albicans revealed by integrative structural biology approach

Yuri Zgadzay1,2, Olga Kolosova2, Artem Stetsenko3, Konstantin Usachev1, Shamil Validov1, Andrey Rogachev4, Albert Guskov3,4, Marat Yusupov1,2

1Laboratory of Structural Biology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia; 2Department of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Illkirch, France; 3Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, the Netherlands; 4Moscow Institute of Physics and Technology, Dolgoprudny, Russia

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