2:45pm - 2:50pmID: 1812
/ MS-81: 1
Introduction
Oral/poster
Introduction to session
Stephen Neidle, Charles Bond
2:50pm - 3:20pmID: 169
/ MS-81: 2
Biological and macromolecular crystallography
Invited lecture to session
MS: Nucleic acids and protein - nuclear acid interactionsKeywords: G-quadruplex DNA, i-motif, X-ray crystallography, ligand binding
Non-canonical DNA structures and their interactions with small molecule ligands
Liliya A. Yatsunyk, Dana Beseiso, Sawyer McCarthy, Erin Chen, Elizabeth Gallagher, Joanne Miao
Swarthmore College, 500 College Ave, Swarthmore, PA, United States of America
3:20pm - 3:50pmID: 1564
/ MS-81: 3
Biological and macromolecular crystallography
Invited lecture to session
MS: Nucleic acids and protein - nuclear acid interactionsKeywords: Alien DNA; crystal structure; helical form; host-guest; unnatural base pair
Structural properties of Alien DNA, an alternative genetic system
Millie M. Georgiadis1, Shuichi Hoshika2, Steven Benner2
1Indiana University School of Medicine, Indianapolis, Indiana, United States of America; 2Foundation for Applied Molecular Evolution, Alachua, Florida, United States of America
3:50pm - 4:10pmID: 849
/ MS-81: 4
Biological and macromolecular crystallography
Oral/poster
MS: Nucleic acids and protein - nuclear acid interactionsKeywords: APE1, DNA repair, Exonuclease, Protein-Nucleic Acid Interaction, Protein-DNA complex
APE1 Exonuclease Distinguishes Various DNA Substrates by an Induced Space-Filling Mechanism.
Tung-Chang Liu2, Chun-Ting Lin1, Kai-Cheng Chang1, Kai-Wei Guo2, Shuying Wang3, Jhih-Wei Chu4, Yu-Yuan Hsiao2
1Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan; 2Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu 30068, Taiwan; 3Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 4Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30068, Taiwan
4:10pm - 4:30pmID: 738
/ MS-81: 5
Bursary application
Oral/poster
MS: Nucleic acids and protein - nuclear acid interactions, Structural biology of viruses - in memory of Michael RossmannSpecial sessions: Exemplary practice in chemical, biological and materials database archivingPosters only: Macromolecular and biological crystallography (if it does not fit to any specific topics), General (if it does not fit to any specific topics nor areas)Keywords: Hereditary breast cancer, BRCA1, BRCT, DNA binding region
Structural characterization of clinically reported missense mutations identified in BRCA1
Neha Mishra, Suchita Dubey, Ashok K Varma
Tata Memorial Centre Advanced Centre for Treatment, Research and Education in Cancer, Mumbai, India
Bibliography Manuscript under preparation
4:30pm - 4:50pmID: 1306
/ MS-81: 6
Biological and macromolecular crystallography
Oral/poster
MS: Nucleic acids and protein - nuclear acid interactions, Macromolecular machines and hybrid methods to crystallographyKeywords: riboswitch, crystal phase transition, time-resolved crystallography, conformational space
Solid-solid phase transition in adenine riboswitch crystals driven by large conformational changes induced by ligand
Jason R. Stagno1, Saminathan Ramakrishnan1, William F. Heinz2, Valentin Magidson2, Xiaobing Zuo3, Yun-Xing Wang1
1Center for Structural Biology, Centre for Cancer Research, National Cancer Institute, Frederick, MD-21702, USA.; 2Optical Microscopy and Analysis Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.; 3X-ray Science Division, Argonne National Laboratory, Lemont, IL 60439, USA
ID: 1500
/ MS-81: 7
Biological and macromolecular crystallography
Poster
MS: Nucleic acids and protein - nuclear acid interactions, Structural biology of eukaryotic immune systems, Structural biology of receptors, signaling and membrane proteinsKeywords: crystal structure; immune system; nucleic acid
Molecular mechanism of self-antigen recognition by the ligand binding domain of B cell inhibitory co-receptor CD72
Nobutaka Numoto1, Kunio Hirata2, Chizuru Akatsu3, Takeshi Tsubata3, Nobutoshi Ito1
1Department of Structural Biology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan; 2RIKEN SPring-8 Center, Hyogo, Japan; 3Department of Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
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