Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

Please note that all times are shown in the time zone of the conference. The current conference time is: 1st Nov 2024, 02:06:39am CET

 
 
Session Overview
Session
MS-26: Solution scattering and combined techniques for biological systems, including component dynamics
Time:
Monday, 16/Aug/2021:
2:45pm - 5:10pm

Session Chair: Frank Gabel
Session Chair: Masaaki Sugiyama
Location: Club B

50 1st floor

Invited: Mitsunori Ikeguchi (Japan), Anne Martel (France)


Session Abstract

This MS will gather together interesting studies focused on clarifying aspects of complex biological systems, such as the equilibrium between association and dissociation of multiple biomacromolecules, as well as the dynamics within each biomacromolecule. Recently, structural biologists have combined several techniques in order to access such issues. In this MS, focusing on solution scattering, SAXS and SANS, and combined techniques including computational science, recent progress will be discussed.

For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction, or individual abstracts below.


Introduction
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Presentations
2:45pm - 2:50pm
ID: 1755 / MS-26: 1
Introduction
Oral/poster

Introduction to session

Frank Gabel, Masaaki Sugiyama



2:50pm - 3:20pm
ID: 907 / MS-26: 2
All topics
Invited lecture to session
MS: Solution scattering and combined techniques for biological systems, including component dynamics system
Keywords: Small Angle Neutron Scattering;Solution structure and dynamics; membrane protein; biological complexes

Motion of a Membrane Enzyme as Seen by SANS

Waqas Javed1,2,3, Christine Ebel1, Cedric Orelle2, Jean-Michel Jault2, Anne Martel3

1IBS; Univ. Grenoble Alpes, CNRS, CEA; Grenoble, 38000; France; 2Molecular Microbiology & Structural Biochemistry (MMSB) UMR 5086; CNRS/University of Lyon; Lyon, 69000; France; 3Institut Laue Langevin, Grenoble, France

External Resource:
Video Link


3:20pm - 3:50pm
ID: 983 / MS-26: 3
All topics
Invited lecture to session
MS: Solution scattering and combined techniques for biological systems, including component dynamics system
Keywords: SAXS; all-atom MD; coarse-grained MD; vitamin D receptor; nucleosome

MD-SAXS: Hybrid method of molecular dynamics simulations and small-angle x-ray scattering experiments

Mitsunori Ikeguchi1,2

1Yokohama City University, Yokohama, Japan; 2RIKEN, Center for Computational Science, Yokohama, Japan

External Resource:
Video Link


3:50pm - 4:10pm
ID: 1172 / MS-26: 4
Biological and macromolecular crystallography
Oral/poster
MS: Solution scattering and combined techniques for biological systems, including component dynamics system
Keywords: SAXS SANS SARS-CoV-2 transcription multimodal

Transient complexes of the Nsp7, Nsp8 and Nsp12 in SARS-CoV-2 replication transcription complex

Greg Hura

Lawrence Berkeley National Laboratory, Berkeley, United States of America

External Resource:
Video Link


4:10pm - 4:30pm
ID: 1025 / MS-26: 5
Biological and macromolecular crystallography
Oral/poster
MS: Solution scattering and combined techniques for biological systems, including component dynamics system
Keywords: Small-angle scattering; protein complex; protein dynamics

The dynamics and interactions of Scs proteins from Proteus mirabilis

Andrew Whitten1, Furlong Emily2, Choudhury Hassanul2, Kurth Fabian2, Duff Anthony1, Martin Jennifer2

1Australian Nuclear Science and Technology Organisation, Lucas Heights, Australia; 2Institute for Molecular Bioscience, University of Queensland, Australia

External Resource:
Video Link


4:30pm - 4:50pm
ID: 981 / MS-26: 6
All topics
Oral/poster
MS: Solution scattering and combined techniques for biological systems, including component dynamics system
Keywords: Multi-domain protein, integrative structural biology, lanthanide ion

Application of a lanthanide tag for evaluation of conformational states of a multidomain protein

Tomohide Saio1, Hiroshi Nakagawa2, Soya Hiramatsu3, Mizue Asada4, Honoka Kawamukai1,3, Toshikazu Nakamura4, Koichiro Ishimori3,5

1Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan; 2Materials Sciences Research Center, Japan Atomic Energy Agency, Tokai, Japan; 3Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo, Japan; 4Instrument Center, Institute for Molecular Science, Okazaki, Japan; 5Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan

External Resource:
Video Link


4:50pm - 5:10pm
ID: 1029 / MS-26: 7
Biological and macromolecular crystallography
Oral/poster
MS: Solution scattering and combined techniques for biological systems, including component dynamics system
Special sessions: Advances in data and model validation in biomolecular Small-Angle Scattering: Impacts on data and meta-data recording and data archiving
Keywords: SAXS, meta-data, objectivity, correction

An Objective Metric to Guide Background Correction and Interepretation of Small Angle X-ray Scattering Data

Yunyun Gao1,2, Timothy R. Stachowski3, Edward H. Snell3, Thomas D. Grant3, Arwen R. Pearson1

1Institute of Nanostructure and Solid State Physics, Universität Hamburg, Hamburg, Germany; 2The Max Planck Institute for the Structure and Dynamics of Matter, Hamburg, Germany; 3Hauptman-Woodward Medical Research Institute, Buffalo, NY, USA

External Resource:
Video Link


 
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