Conference Agenda

ID: 1975 / Poster - 48 Fragment screening: 1
Poster session abstracts
Poster

Poster session abstracts

Radomír Kužel

ID: 1479 / Poster - 48 Fragment screening: 2
Biological and macromolecular crystallography
Poster
MS: Fragment screening - 1 project, 100 datasets
Keywords: crystallographic fragment screening, spliceosome, protein-protein interaction, structure-guided drug design

Hundreds of starting points for spliceosomal PPI modulators identified by crystallographic fragment screening with the F2X-Universal Library

Tatjana Barthel^1,3, Jan Wollenhaupt¹, Gustavo M. A. Lima², Markus C. Wahl³, Manfred S. Weiss¹

¹Helmholtz-Zentrum Berlin, Macromolecular Crystallography, Albert-Einstein-Str. 15, 12489 Berlin, Germany; ²MAX IV Laboratory, BioMAX, Fotongatan 2, 224 84 Lund, Sweden; ³Freie Universität Berlin, Institute of Chemistry and Biochemistry, Laboratory of Structural Biochemistry, Takustraße 6, 14195 Berlin, Germany

ID: 1404 / Poster - 48 Fragment screening: 3
Biological and macromolecular crystallography
Poster
MS: Fragment screening - 1 project, 100 datasets, Structure guided drug design and antibiotic resistance targets, Structural biology of enzymes, mechanism and regulation
Posters only: Macromolecular and biological crystallography (if it does not fit to any specific topics)
Keywords: Anaemia, Hypoxia-inducible factor (HIF), Prolyl-hydroxylases (PHDs), Oxygenases, Molidustat

HIF-Prolyl-Hydroxylase 2 Clinical Inhibitor Complex Structure and XChem Fragment-Based Screen Obtained with Succinate Co-Product Used as a Crystallisation Tool.

William D. Figg Jr¹, Michael A. McDonough¹, Yu Nakashima^1,3, Rasheduzzaman Chowdhury^1,2, Christopher J. Schofield¹

¹Department of Chemistry, University of Oxford, Oxford, United Kingdom; ²Cardiovascular Research Institute, University of California, San Fransciso, CA, United States; ³Institute of Natural Medicine, University of Toyama, Toyama, Japan

ID: 1062 / Poster - 48 Fragment screening: 4
Biological and macromolecular crystallography
Oral/poster
MS: Fragment screening - 1 project, 100 datasets
Keywords: fragment screening, protein crystallography, drug discovery

Updates from FragMAX, a crystallographic fragment screening platform at MAX IV Laboratory

Tobias Krojer

MAX IV Laboratory, Lund University, PO Box 118, S-221 00 Lund, Sweden