| Session | ||
MS-2: Validation of cryoEM structures and maps
Invited: Florence Tama (Japan), Pavel Afonine (USA), G. Kleywegt (Germany) | ||
| Session Abstract | ||
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New achievements in Cryo-electron microscopy enabled a revolution in structural biology and over the last few years reached resolutions comparable with crystallography. Still, quantitative assessment of these structures is urgently needed, and essential for the validation of all these new EMDB and PDB entries. New algorithms tailored to the nature of these data need to be developed and made widely available to the community. This session will present the advancements in this field. For all abstracts of the session as prepared for Acta Crystallographica see external PDF, or individual abstracts below. | ||
| Presentations | ||
10:20am - 10:50am
ID: 126 / MS-2: 1 All topics Invited lecture to session MS: Validation of cryoEM structures and maps Keywords: hydrogen bond, Phenix, crystallography, cryo-EM, validation Protein hydrogen bond parameters as a new validation tool 1Lawrence Berkeley National Laboratory, Berkeley, United States of America; 2International Center for Quantum and Molecular Structures, Shanghai University, Shanghai 200444, People's Republic of China; 3Bioscience Division, Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545, USA; 4New Mexico Consortium, Los Alamos, NM 87544, USA; 5Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA 10:50am - 11:20am
ID: 1234 / MS-2: 2 Biological and macromolecular crystallography Invited lecture to session MS: Validation of cryoEM structures and maps Keywords: cryo-EM, flexible fitting, dynamics, biomolecules Integrative modeling to characterize structure and dynamics of biomolecules Nagoya University & RIKEN, Nagoya, Japan 11:20am - 11:50am
ID: 385 / MS-2: 3 All topics Invited lecture to session MS: Validation of cryoEM structures and maps Keywords: Validation Community recommendations on validating cryo-EM models and data EMBL EBI, Cambridge, United Kingdom 11:50am - 12:05pm
ID: 1256 / MS-2: 4 Biological and macromolecular crystallography Oral/poster MS: Validation of cryoEM structures and maps, CryoEM for macromolecules - from single particles to microcrystals Posters only: General (if it does not fit to any specific topics nor areas) Keywords: EMDA, cryo-EM, correlation, likelihood, signal Cryo-EM Validation Metrics in EMDA MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, Biomedical Campus, Cambridge, CB2 0QH, UK 12:05pm - 12:20pm
ID: 1095 / MS-2: 5 All topics Oral/poster MS: Validation of cryoEM structures and maps Posters only: Theory, computation, modeling, data, standards (if it does not fit to any specific topics) Keywords: CryoEM, map-to-model validation, local resolution FSC-Q: A method for quality analysis of cryoEM-derived models CNB-CSIC, Madrid, Spain 12:20pm - 12:35pm
ID: 1294 / MS-2: 6 Biological and macromolecular crystallography Oral/poster MS: Validation of cryoEM structures and maps Keywords: CryoEM, Validation, Structural Biology, Challenges, Data Archiving Outcomes from EMDataResource model challenges 1Rutgers University, NJ, USA; 2University of California Davis, CA, USA; 3Stanford University/SLAC, Stanford, CA, USA 12:35pm - 12:50pm
ID: 1174 / MS-2: 7 All topics Oral/poster MS: Validation of cryoEM structures and maps Keywords: cryo-EM, model, structure, Q-scores, resolution Quantifiying resolvability of atomic features in cryo-EM maps using Q-scores 1Stanford University; 2Stanford University, SLAC National Accelerator Laboratory; 3Stanford University, SLAC National Accelerator Laboratory | ||