Session | ||
MS-81: Nucleic acids and binding proteins structure and function
Invited: Millie Georgiadis (USA), Liliya Yatsunyk (USA) | ||
Session Abstract | ||
Structural biology is particularly sucessful in elucidating how proteins recognize nucleic acids in various physiological process from decoding genetic information, maintenance of the genome, through RNA turnover to name a few. Recent advancements in the field will be presented in this session. | ||
Presentations | ||
2:45pm - 2:50pm
ID: 1812 / MS-81: 1 Introduction Oral/poster Introduction to session 2:50pm - 3:20pm
ID: 169 / MS-81: 2 Biological and macromolecular crystallography Invited lecture to session MS: Nucleic acids and protein - nuclear acid interactions Keywords: G-quadruplex DNA, i-motif, X-ray crystallography, ligand binding Non-canonical DNA structures and their interactions with small molecule ligands Swarthmore College, 500 College Ave, Swarthmore, PA, United States of America External Resource: https://www.xray.cz/iucrv/vidp.asp?id=564
3:20pm - 3:50pm
ID: 1564 / MS-81: 3 Biological and macromolecular crystallography Invited lecture to session MS: Nucleic acids and protein - nuclear acid interactions Keywords: Alien DNA; crystal structure; helical form; host-guest; unnatural base pair Structural properties of Alien DNA, an alternative genetic system 1Indiana University School of Medicine, Indianapolis, Indiana, United States of America; 2Foundation for Applied Molecular Evolution, Alachua, Florida, United States of America External Resource: https://www.xray.cz/iucrv/vidp.asp?id=565
3:50pm - 4:10pm
ID: 849 / MS-81: 4 Biological and macromolecular crystallography Oral/poster MS: Nucleic acids and protein - nuclear acid interactions Keywords: APE1, DNA repair, Exonuclease, Protein-Nucleic Acid Interaction, Protein-DNA complex APE1 Exonuclease Distinguishes Various DNA Substrates by an Induced Space-Filling Mechanism. 1Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan; 2Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu 30068, Taiwan; 3Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; 4Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30068, Taiwan External Resource: https://www.xray.cz/iucrv/vidp.asp?id=566
4:10pm - 4:30pm
ID: 738 / MS-81: 5 Bursary application Oral/poster MS: Nucleic acids and protein - nuclear acid interactions, Structural biology of viruses - in memory of Michael Rossmann Special sessions: Exemplary practice in chemical, biological and materials database archiving Posters only: Macromolecular and biological crystallography (if it does not fit to any specific topics), General (if it does not fit to any specific topics nor areas) Keywords: Hereditary breast cancer, BRCA1, BRCT, DNA binding region Structural characterization of clinically reported missense mutations identified in BRCA1 Tata Memorial Centre Advanced Centre for Treatment, Research and Education in Cancer, Mumbai, India Bibliography
Manuscript under preparation External Resource: https://www.xray.cz/iucrv/vidp.asp?id=567
4:30pm - 4:50pm
ID: 1306 / MS-81: 6 Biological and macromolecular crystallography Oral/poster MS: Nucleic acids and protein - nuclear acid interactions, Macromolecular machines and hybrid methods to crystallography Keywords: riboswitch, crystal phase transition, time-resolved crystallography, conformational space Solid-solid phase transition in adenine riboswitch crystals driven by large conformational changes induced by ligand 1Center for Structural Biology, Centre for Cancer Research, National Cancer Institute, Frederick, MD-21702, USA.; 2Optical Microscopy and Analysis Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.; 3X-ray Science Division, Argonne National Laboratory, Lemont, IL 60439, USA External Resource: https://www.xray.cz/iucrv/vidp.asp?id=568
ID: 1500
/ MS-81: 7
Biological and macromolecular crystallography Poster MS: Nucleic acids and protein - nuclear acid interactions, Structural biology of eukaryotic immune systems, Structural biology of receptors, signaling and membrane proteins Keywords: crystal structure; immune system; nucleic acid Molecular mechanism of self-antigen recognition by the ligand binding domain of B cell inhibitory co-receptor CD72 1Department of Structural Biology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan; 2RIKEN SPring-8 Center, Hyogo, Japan; 3Department of Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan External Resource: https://www.xray.cz/iucrv/vidp.asp?id=569
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