Session | ||
MS-34a: Structural biology of enzymes, mechanism and regulation
Invited: Liang Wu (UK), Orsolya Barabas (Germany) | ||
Session Abstract | ||
How does crystallography provide understanding of enzymes. This topic could also include recent advances in the area of time resolved crystallography. For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction, or individual abstracts below. The session continues in MS-92. | ||
Introduction | ||
Presentations | ||
10:20am - 10:25am
ID: 1764 / MS-34a: 1 Introduction Oral/poster Introduction to session 10:25am - 10:55am
ID: 995 / MS-34a: 2 Biological and macromolecular crystallography Invited lecture to session MS: Structural biology of enzymes, mechanism and regulation Keywords: Inhibitors, Heparan Sulfate, Glycosaminoglycans, Heparanase Adventures in heparan sulfate degradation 1The Rosalind Franklin Institute, Didcot, OX11 0FA, United Kingdom; 2Department of Chemistry, University of York, York, YO10 5DD, United Kingdom; 3Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands; 4Technion Integrated Cancer Center (TICC), The Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel External Resource: https://www.xray.cz/iucrv/vidp.asp?id=261
10:55am - 11:25am
ID: 787 / MS-34a: 3 Biological and macromolecular crystallography Oral/poster MS: Structural biology of enzymes, mechanism and regulation Keywords: Fatty Acid Photodecarboxylase, Reaction mechanism, Alkane biosynthesis High-resolution structure and reaction cycle of Fatty Acid Photodecarboxylase: anatomy of a crime scene 1CEA, Saint Paul lez Durance, France; 2IBS, Grenoble, France; 3ESRF, Grenoble, France; 4SOLEIL, Gif-sur-Yvette, France; 5Lomonosov Moscow State University, Moscow, Russia; 6I2BC,Gif-sur-Yvette, France; 7Ecole Polytechnique, Palaiseau, France; 8MPI, Heidelberg, Germany External Resource: https://www.xray.cz/iucrv/vidp.asp?id=262
11:25am - 11:45am
ID: 141 / MS-34a: 4 Biological and macromolecular crystallography Oral/poster MS: Structural biology of enzymes, mechanism and regulation Keywords: monooxygenase, O2 activation, protonation state, neutron crystallography Structural insights into the enzymatic mechanism of lytic polysaccharide monooxygenases NC State / ORNL, Raleigh, United States of America External Resource: https://www.xray.cz/iucrv/vidp.asp?id=263
11:45am - 12:05pm
ID: 1240 / MS-34a: 5 Biological and macromolecular crystallography Oral/poster MS: Solution scattering and combined techniques for biological systems, including component dynamics system, Structural biology of enzymes, mechanism and regulation Keywords: Glucosamine kinase, antibiotic production, X-ray crystallography, small-angle X-ray scattering Structural studies on a unique glucosamine kinase unveil a novel enzyme family 1IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal; 2Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; 3CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; 4PhD Program in Experimental Biology and Biomedicine (PDBEB), University of Coimbra, Coimbra, Portugal External Resource: https://www.xray.cz/iucrv/vidp.asp?id=264
12:05pm - 12:25pm
ID: 1287 / MS-34a: 6 Biological and macromolecular crystallography Oral/poster MS: Structural biology of enzymes, mechanism and regulation Keywords: Mycobacterium, polymethylated polysaccharides, sugar methyltransferase, S-adenosyl-L-methionine, 3D structure Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides 1IBMC – Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; 2Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; 3CNC – Center for Neuroscience and Cell Biology, 3004-504 Coimbra, Portugal.; 4ITQB – Instituto de Tecnologia Química Biológica, Universidade Nova de Lisboa, 2780-157 Oeiras, Portugal.; 5IIIUC - Interdisciplinary Research Institute, University of Coimbra, 3004-504 Coimbra, Portugal. External Resource: https://www.xray.cz/iucrv/vidp.asp?id=265
12:25pm - 12:45pm
ID: 491 / MS-34a: 7 Bursary application Oral/poster MS: Structural biology of enzymes, mechanism and regulation Keywords: x-ray free electron lasers; time-resolved studies; photoswitchable fluorescent proteins Time-resolved serial femtosecond crystallography on photoswitchable fluorescent proteins Institut de Biologie Strucutrale, Grenoble, France Bibliography
Publications in preparation External Resource: https://www.xray.cz/iucrv/vidp.asp?id=266
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