Conference Agenda

10:20am - 10:25am

Introduction to session

Mirham Czjzek

10:25am - 10:55am

Adventures in heparan sulfate degradation

Liang Wu¹, Zachary Armstrong², Casper de Boer³, Vincent Lit³, Gijs Ruijgrok³, Uri Barash⁴, Ilanit Boyango⁴, Neta Ilan⁴, Israel Vlodavsky⁴, Hermen S Overkleeft³, Gideon J Davies²

¹The Rosalind Franklin Institute, Didcot, OX11 0FA, United Kingdom; ²Department of Chemistry, University of York, York, YO10 5DD, United Kingdom; ³Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands; ⁴Technion Integrated Cancer Center (TICC), The Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel

10:55am - 11:25am

High-resolution structure and reaction cycle of Fatty Acid Photodecarboxylase: anatomy of a crime scene

Damien Sorigue¹, Kyprianos Hadjidemetriou², Stéphanie Blangy¹, Guillaume Gotthard³, Pierre Legrand⁴, Didier Nurizzo³, Antoine Royant³, Catherine Berthomieu¹, Martin Weik², Tatiana Domratcheva⁵, Klaus Brettel⁶, Martin Vos⁷, Ilme Schlichting⁸, Pavel Muller⁶, Fred Beisson¹, Pascal Arnoux¹

¹CEA, Saint Paul lez Durance, France; ²IBS, Grenoble, France; ³ESRF, Grenoble, France; ⁴SOLEIL, Gif-sur-Yvette, France; ⁵Lomonosov Moscow State University, Moscow, Russia; ⁶I2BC,Gif-sur-Yvette, France; ⁷Ecole Polytechnique, Palaiseau, France; ⁸MPI, Heidelberg, Germany

11:25am - 11:45am

Structural insights into the enzymatic mechanism of lytic polysaccharide monooxygenases

Flora Meilleur

NC State / ORNL, Raleigh, United States of America

11:45am - 12:05pm

Structural studies on a unique glucosamine kinase unveil a novel enzyme family

Jose Antonio Manso^1,2, Daniela Nunes Costa^3,4, Sandra Macedo Ribeiro^1,2, Nuno Empadinhas^3,4, Pedro Jose Barbosa Pereira^1,2

¹IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal; ²Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; ³CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; ⁴PhD Program in Experimental Biology and Biomedicine (PDBEB), University of Coimbra, Coimbra, Portugal

12:05pm - 12:25pm

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides

Jorge Ripoll-Rozada^1,2, Mafalda Costa³, José Antonio Manso^1,2, Ana Maranha³, Vanessa Miranda⁴, André Sequeira⁴, Maria Rita Ventura⁴, Sandra Macedo-Ribeiro^1,2, Nuno Empadinhas^3,5, Pedro José Barbosa Pereira^1,2

¹IBMC – Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; ²Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; ³CNC – Center for Neuroscience and Cell Biology, 3004-504 Coimbra, Portugal.; ⁴ITQB – Instituto de Tecnologia Química Biológica, Universidade Nova de Lisboa, 2780-157 Oeiras, Portugal.; ⁵IIIUC - Interdisciplinary Research Institute, University of Coimbra, 3004-504 Coimbra, Portugal.

12:25pm - 12:45pm

Time-resolved serial femtosecond crystallography on photoswitchable fluorescent proteins

Kyprianos Hadjidemetriou

Institut de Biologie Strucutrale, Grenoble, France