10:20am - 10:50amID: 126
/ MS-2: 1
All topics
Invited lecture to session
MS: Validation of cryoEM structures and mapsKeywords: hydrogen bond, Phenix, crystallography, cryo-EM, validation
Protein hydrogen bond parameters as a new validation tool
Pavel Afonine1, Oleg Sobolev1, Nigel Moriarty1, Yanting Xu1,2, Thomas Terwilliger3,4, Paul Adams1,5
1Lawrence Berkeley National Laboratory, Berkeley, United States of America; 2International Center for Quantum and Molecular Structures, Shanghai University, Shanghai 200444, People's Republic of China; 3Bioscience Division, Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545, USA; 4New Mexico Consortium, Los Alamos, NM 87544, USA; 5Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA
10:50am - 11:20amID: 1234
/ MS-2: 2
Biological and macromolecular crystallography
Invited lecture to session
MS: Validation of cryoEM structures and mapsKeywords: cryo-EM, flexible fitting, dynamics, biomolecules
Integrative modeling to characterize structure and dynamics of biomolecules
Florence Tama
Nagoya University & RIKEN, Nagoya, Japan
11:20am - 11:50amID: 385
/ MS-2: 3
All topics
Invited lecture to session
MS: Validation of cryoEM structures and mapsKeywords: Validation
Community recommendations on validating cryo-EM models and data
Gerard Kleywegt
EMBL EBI, Cambridge, United Kingdom
11:50am - 12:05pmID: 1256
/ MS-2: 4
Biological and macromolecular crystallography
Oral/poster
MS: Validation of cryoEM structures and maps, CryoEM for macromolecules - from single particles to microcrystalsPosters only: General (if it does not fit to any specific topics nor areas)Keywords: EMDA, cryo-EM, correlation, likelihood, signal
Cryo-EM Validation Metrics in EMDA
Rangana Warshamanage, Keitaro Yamashita, Garib N. Murshudov
MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, Biomedical Campus, Cambridge, CB2 0QH, UK
12:05pm - 12:20pmID: 1095
/ MS-2: 5
All topics
Oral/poster
MS: Validation of cryoEM structures and mapsPosters only: Theory, computation, modeling, data, standards (if it does not fit to any specific topics)Keywords: CryoEM, map-to-model validation, local resolution
FSC-Q: A method for quality analysis of cryoEM-derived models
Erney RamÃrez-Aportela, David Maluenda, Yunior C. Fonseca, Pablo Conesa, Roberto Marabini, Carlos Oscar S. Sorzano, Jose M. Carazo
CNB-CSIC, Madrid, Spain
12:20pm - 12:35pmID: 1294
/ MS-2: 6
Biological and macromolecular crystallography
Oral/poster
MS: Validation of cryoEM structures and mapsKeywords: CryoEM, Validation, Structural Biology, Challenges, Data Archiving
Outcomes from EMDataResource model challenges
Catherine Lawson1, Andriy Kryshstafovych2, Wah Chiu3
1Rutgers University, NJ, USA; 2University of California Davis, CA, USA; 3Stanford University/SLAC, Stanford, CA, USA
12:35pm - 12:50pmID: 1174
/ MS-2: 7
All topics
Oral/poster
MS: Validation of cryoEM structures and mapsKeywords: cryo-EM, model, structure, Q-scores, resolution
Quantifiying resolvability of atomic features in cryo-EM maps using Q-scores
Greg Pintilie1, Michael Schmid2, Wah Chiu3
1Stanford University; 2Stanford University, SLAC National Accelerator Laboratory; 3Stanford University, SLAC National Accelerator Laboratory
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