Session | ||
MS-19: Crystal structures of pharmaceutical and organic compounds from electron diffraction
Invited: Enrico Mugnaioli (Italy), Brent Nannega (USA) | ||
Session Abstract | ||
Many drugs are provided as microcrystalline compounds. Their uptake in the body, the optimisation of their effectivity, and the minimisation of side effects is guided by properties of crystal packing and inter-particle interactions. As a consequence, 3D electron crystallography has attracted increasing attention in the characterisation of pharmaceutical and organic compounds. This microsymposium aims to discuss possibilities and future directions of 3D electron crystallography. For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction, or individual abstracts below. | ||
Introduction | ||
Presentations | ||
10:20am - 10:25am
Introduction to session 10:25am - 10:55am
Combining MicroED and GIWAXS for determining structure and orientation of organic semiconductor thin films Arizona State University, Tempe, United States of America External Resource: https://www.xray.cz/iucrv/vidp.asp?id=159
10:55am - 11:25am
Strategies for structure solution of small-molecule organics by 3D ED using a small beam 1Center for Nanotechnology Innovation@NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, Pisa 56127, Italy; 2NanoMEGAS SPRL, Rue Émile Claus 49 bte 9, Brussels1050, Belgium External Resource: https://www.xray.cz/iucrv/vidp.asp?id=160
11:25am - 11:45am
The crystal structure determination of an organic dye with triclinic symmetry by electron diffraction 1LENS, MIND/IN2UB, University of Barcelona, Barcelona, Catalonia; 2Institut für Angewandte Geowissenschaften, Technische Universität Darmstadt, Darmstadt, Germany; 3Fyzikální Ústav, Akademie vĕd České Republiky, Prague, Czech Republic; 4NanoMegas SPRL, Brussels, Belgium; 5Institut für Anorganische Chemie und Analytische Chemie, Goethe-Universität Frankfurt, Frankfurt, Germany; 6Institut für Anorganische Chemie und Analytische Chemie, Johannes Gutenberg-Universität Mainz, Mainz, Germany External Resource: https://www.xray.cz/iucrv/vidp.asp?id=161
11:45am - 12:05pm
Refinement with multipolar scattering factors Biological and Chemical Research Centre, Department of Chemistry, University of Warsaw, Poland External Resource: https://www.xray.cz/iucrv/vidp.asp?id=162
12:05pm - 12:25pm
Improving data quality for 3D electron diffraction (3DED) by Gatan Image Filter Stockholm University, Stockholm, Sweden External Resource: https://www.xray.cz/iucrv/vidp.asp?id=163
12:25pm - 12:45pm
3D electron diffraction: a dedicated device for structural elucidation of nanocrystalline particles ELDICO Scientific AG, 5234 Villigen, Switzerland External Resource: https://www.xray.cz/iucrv/vidp.asp?id=164
|