Tamir Gonen investigates the structure and function of cell membrane proteins that act as receptors, channels, and transporters and play critical roles in homeostasis and signaling, as well as nutrient, ion, and water uptake. His work seeks to understand how the thousands of channels and transporters in a single cell membrane maintain homeostasis – keeping that cell in balance and functioning properly. While leading a lab at the HHMI Janelia Research Campus he began developing Microcrystal Electron Diffraction (MicroED) as a new method for cryoEM and structural biology.