Poster session abstracts
Radomír Kužel
MyD88 TIR domain higher-order assembly interactions revealed by serial femtosecond crystallography
Susannah Holmes1,10, Max T. B. Clabbers2,10,11, Timothy W. Muusse3, Parimala R. Vajjhala3, Sara J. Thygesen3, Alpeshkumar K. Malde4, Dominic J. B. Hunter3,5,6, Tristan I. Croll7, Leonie Flueckiger1, Jeffrey D. Nanson3, Md. Habibur Rahaman3, Andrew Aquila8, Mark S. Hunter8, Mengning Liang8, Chun Hong Yoon8, Jingjing Zhao2, Nadia A. Zatsepin1, Brian Abbey1, Emma Sierecki5, Yann Gambin5, Katryn J. Stacey3,6,9, Connie Darmanin1, Bostjan Kobe3,6,9, Hongyi Xu2, Thomas Ve4
1Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia; 2Department of Materials and Environmental Chemistry, Stockholm University, Stockholm, Sweden; 3School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia; 4Institute for Glycomics, Griffith University, Southport, Queensland, Australia; 5EMBL Australia Node in Single Molecule Science, University of New South Wales, Kensington, New South Wales, Australia; 6Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia; 7Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK; 8Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, California, USA; 9Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland, Australia; 10These authors contributed equally: Susannah Holmes, Max T. B. Clabbers; 11Present address: Department of Biological Chemistry, University of California Los Angeles, Los Angeles, California, USA
Crystal structure of atypical ubiquitin ligase PCAF_N
Sachiko TOMA-FUKAI1, Ryota HIBI2, Takao NAGANUMA3, Mashito SAKAI3, Shinya SAIJO4, Nobutaka SHIMIZU4, Michihiro MATSUMOTO3, Toshiyuki SHIMIZU2
1Nara Institute of Science and Technology; 2The University of Tokyo; 3National Center for Global Health and Medicine; 4High Energy Accelerator Research Organization (KEK)
Structural characterization of seven-bladed beta-propeller lectin family from Photorhabdus laumondii
Eva Fujdiarova1,2, Josef Houser1,2, Filip Melicher2, Michaela Wimmerová1,2,3
1National Centre for Biomolecular research, Masaryk University, Brno, Czech Republic; 2Central European Institute of Technology, Brno, Czech Republic; 3Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic
Structural study of the inhibitory mechanism of tau recognition antibody to tau aggregation
Tomohiro Tsuchida1, Takahiro Tsuchiya1, Katsushiro Miyamoto1, Shinji Takai1, Teruo Ueno1, Yoshihiko Fujioka1, Yasuko In1, Katsuhiko Minoura1, Taizo Taniguchi2, Koji Tomoo1
1Osaka Medical and Pharmaceutical University, Osaka, Japan; 2Pharmacrea Kobe, Hyogo, Japan
Molecular-biology and structural study of Avian orthoreovirus non-structural proteins
Barbora Kaščáková1, Zdenek Franta1, Zdeno Gardian1,2, Ivana Kutá Smatanová1, Roman Tůma1,3
1University of South Bohemia in České Budějovice, České Budějovice, Czech Republic; 2Biology Centre CAS, Laboratory of electron Microscopy, Ceske Budejovice, Czech Republic; 3University of Leeds, School of Molecular and Cellular Biology, The Astbury Centre for Structural Molecular Biology, Leeds, UK
Surface Layer Proteins of Lactobacillus acidophilus - A Story of SlpA and SlpX
Theo Sagmeister1, Markus Eder1, Christoph Grininger1, Christoph Buhlheller1, Đjenana Vejzović1, Andela Đordić1, Elisabeth Damisch1, Claudia Millán2, Isabel Usón3, Tea Pavkov-Keller1,4,5
1Institute of Molecular Biosciences, University of Graz, Austria; 2Structural Biology, Crystallographic Methods group at IBMB-CSIC, Barcelona; 3Structural Biology, ICREA at IBMB-CSIC, Barcelona; 4BioTechMed, Graz; 5Field of Excellence BioHealth, University of Graz, 8010 Graz, Austria
Structural characterization of the PTG and PTG/PP1 complex
Marta Stefania Semrau1,2, Graziano Lolli1, Paola Storici2, Gabriele Giachin3, Sonia Covaceuszach4
1University of Trento, Department of Cellular, Computational and Integrative Biology (CIBIO), Trento, Italy.; 2Protein Facility, Elettra Sincrotrone Trieste S.C.p.A, Italy; 3University of Padova, Department of Chemical Sciences (DiSC), Padova, Italy; 4CNR – Institute of Crystallography, Trieste, Italy
OrfG, a VirB8-like protein encoded by an integrative and conjugative element in S. thermophilus, has a trimeric architecture with intertwined subunits that may be involved in the Gram-positive Conj-T4SS.
Julien Cappele1, Badreddine Douzi2, Sandrine Mathiot1, Nathalie Leblond-Bourget2, Claude Didierjean1, Frédérique Favier1
1CRM², Nancy, France; 2Université de Lorraine, INRAE, DynAMic, Nancy, France
A solution-free crystal-mounting platform for native SAD
Jian Yu, Akira Shinoda, Koji Kato, Isao Tanaka, Toyoyuki Ose, Min Yao
Faculty of Advanced Life Science, Hokkaidou University, Sapporo, Japan
Structural insights into the phlorotannin binding of EHEP and akuBGL for producing biofuel from brown algae
xiaomei sun1, Yuxin Ye1, Naofumi Sakurai1, Koji Kato1, Jian Yu1, Keizo Yuasa2, Akihiko Tsuji2, Min Yao1
1Faculty of Advanced Life Science, Hokkaido university; 2Graduate School of Bioscience and Bioindustry, Tokushima University
Structural studies of C-reactive Protein
Stacey Marie Collister, William Neale, Jamie Littlejohn, Trevor Greenhough, Annette Shrive
Keele University, Staffordshire, United Kingdom
Structural studies of bacterial small alarmone hydrolases
Adriana Chrenková, Francesco Bisiak, Ditlev Egeskov Brodersen
Aarhus University, Aarhus, Denmark
Investigation of possible tolerance mutations in a VapBC Toxin-Antitoxin system through structure determination
Maria Raadkjær Nielsen, Ditlev Egeskov Brodersen
Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10, DK-8000, Aarhus C, Denmark
Investigations on Vibrio cholerae sensory regulator ToxR
Nina Gubensäk, Gabriel E. Wagner, Evelyne Schrank, Fabio S. Falsone, Tamara Margot Ismael Berger, Joachim Reidl, Klaus Zangger, Tea Pavkov-Keller
University of Graz, Graz, Austria
FAD-dependent oxidoreductase from Chaetomium thermophilum: Crystallographic fragment screening-based identification of putative substrates
Leona Švecová1,2, Lars Henrik Østergaard3, Tereza Skálová1, Tomáš Kovaľ1, Jan Dohnálek1
1Institute of Biotechnology of the Czech Academy of Sciences, v.v.i., Průmyslová 595, 252 50 Vestec, Czech Republic; 2Faculty of Nuclear Sciences and Physical Engineering, Czech Technical University in Prague, Břehová 7, 115 19 Prague 1, Czech Republic; 3Novozymes A/S, Biologiens Vej 2, 2800 Kgs. Lyngby, Denmark,
Structure-assisted design of inhibitors of CA IX enzyme based on polyhedral boron compounds
Jiří Brynda1,4, Michael Kugler1,4, Jan Nekvinda2, Josef Holub2, Suzan El Anwar2, Wiswanath Das3, Václav Šícha2, Klára Pospíšilová1, Milan Fábry4, Vlastimil Král4, Petr Pachl1, Marián Hajdůch3, Bohumír Grüner2, Pavlína Řezáčová1,4
1Institute of Organic Chemistry and Biochemistry AS CR, Praha, Czech Republic; 2Institute of Inorganic Chemistry of the Czech Academy of Sciences; 3Institute of Molecular and Translational Medicine; 4Institute of Molecular Genetics of the Czech Academy of Sciences
Understanding the structural and functional aspects of a novel Mg2+-citrate-binding protein
Suraj Kumar Mandal, Shankar Prasad Kanaujia
Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India, Guwahati, India
MlaC represents a unique class of solute-binding proteins
Angshu Dutta, Shankar Prasad Kanaujia
Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Guwahati , India
Evolutionary upgrade of stefins for secretion in parasites
Michal Buša1, Zuzana Matoušková1, Pavlína Řezáčová1, Pavla Sojková-Bartošová2, Martin Horn1, Saša Štefanič3, Michael Mareš1
1Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, Prague, 166 10, Czechia; 2Institute of Parasitology, Biology Centre of Czech Academy of Sciences, Branišovská 1160/31, České Budějovice, 370 05, Czechia; 3Institute of Parasitology, University of Zurich, Winterthurerstrasse, Zurich, CH-8057, Switzerland
Light-induced oligomerization of the transcription factor EL222
Aditya S. Chaudhari1, Edel Cunill Semanat1, Anne Martel2, Bohdan Schneider1, Gustavo Fuertes1
1Institute of Biotechnology CAS v.v.i., Vestec, Czech Republic; 2Institut Laue-Langevin, Grenoble, France
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