Poster session abstracts

Radomír Kužel

Fragment Based Drug Discovery of SARS-CoV-2 Main Protease

Weixiao Song, Sen Li, AhWing Edith Chan, Alun Coker

University College London, London, United Kingdom

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Repurposing an ancient protein core structure: structural studies on FmtA, a novel esterase of Staphylococcus aureus

vikram Dalal¹, Pramod Kumar¹, Gaddy Rakhaminov², Aneela Qamar², Xin Fan², Howard Hunter², Shailly Tomar¹, Dasantila Golemi-Kotra², Pravindra Kumar¹

¹Department of Biotechnology, IIT Roorkee, Roorkee, India; ²Department of Biology,York University, 4700 Keele Street, Toronto, Canada

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Studies of LysSi3, a Gram-negative targeting endolysin with broad bactericidal activity.

Tatyana Prudnikova¹, Daria V Vasina², Dmitry Loginov¹, Ivana Kuta Smatanova¹

¹Laboratory of Structural Chemistry, Institute of Chemistry, Faculty of Science, University of South Bohemia in České Budějovice, Czech Republic; ²N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.

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Structural insight into the degradation selectivity of C2H2 zinc finger by thalidomide metabolite

Hirotake Furihata¹, Satoshi Yamanaka², Toshiaki Honda³, Norio Shibata³, Masaru Tanokura¹, Tatsuya Sawasaki², Takuya Miyakawa¹

¹Graduate School of Agricultural and Life Sciences, The University of Tokyo; ²Proteo-Science Center, Ehime University; ³Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology

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Structure determination of the motor domain of centromere associated protein E

Asuka Shibuya¹, Naohisa Ogo², Jun-ichi Sawada², Akira Asai², Hideshi Yokoyama¹

¹Faculty of Pharmaceutical Sciences, Tokyo University of Science; ²Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka

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Structural studies towards the development of an oral main protease (Mpro) inhibitor to treat SARS-CoV-2 infection

Joanne Lemieux¹, Muhammad Bashir Khan¹, Arutyunova Arutyunova¹, Jimmy Lu¹, James Nieman³, D. Lorne Tyrrell², Howard S Young¹

¹Department of Biochemistry, University of Alberta, Edmonton, Canada; ²Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada; ³Li Ka Shing Applied Virology Institute, University of Alberta, Edmonton, Alberta, Canada,

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