Poster session abstracts
Radomír Kužel
Structural characterisation of mitochondrial complex IV assembly factors
Shadi Magool1, Luke Formosa2, Dinesha Cooray3, David Stroud4, David Aragão5, Michael Ryan2, Megan Maher1
1School of Chemistry and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Australia; 2Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton 3800, Australia; 3Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne 3086, Australia; 4Department of Biochemistry and Molecular Biology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia; 5Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK
Chemical biology and structural studies on the mechanism of regulation of phosphoinositide-dependent protein kinase 1 (PDK1)
Lissy Z. F. Gross1, Mariana Sacerdoti1, Alejandro E. Leroux1, Abhijeet Ghode4, Ganesh S. Anand4, Jörg O. Schulze2, Melissa A. Graewert5, Dmitri I. Svergun5, Sebastian Klinke3, Ricardo M. Biondi1,2
1IBioBA - CONICET - Partner Institute of the Max Planck Society, Buenos Aires, Argentine Republic; 2Department of Internal Medicine I, Universitätsklinikum Frankfurt, Germany; 3Leloir Institute - CONICET, Buenos Aires, Argentine Republic; 4Department of Biological Sciences, National University of Singapore, Singapore; 5European Molecular Biology Laboratory (EMBL), DESY Hamburg, Germany
Structure of the Caulobacter Crescentus suppressor of copper sensitivity protein C
Guillaume A. Petit1, Karrera Y. Djoko2, Jennifer L. Martin1,3, Maria A. Halili1
1Griffith Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia; 2Department of Biosciences, Durham University, UK; 3Vice-Chancellor’s Unit, University of Wollongong, NSW, Australia
The structural panorama of L-asparaginases includes an alien from nitrogen-fixing bacteria
Mariusz Jaskolski1, Joanna Loch2, Mirek Gilski1, Barbara Imiolczyk3
1Faculty of Chemistry, A.Mickiewicz University, Poznan, Poland, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland; 2Faculty of Chemistry, Jagiellonian University, Cracow, Poland; 3Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
Structures of a DYW domain shed first light on a unique plant RNA editing regulation principle
Mizuki Takenaka1, Sachi Takenaka1, Tatjana Barthel2, Brody Frink1, Sascha Haag3, Daniil Verbitskiy3, Bastian Oldenkott4, Mareike Schallenberg-Rüdinger4, Christian Feiler2, Manfred S. Weiss2, Gottfried J. Palm5, Gert Weber2
1Department of Botany, Graduate School of Science, Kyoto University, Kyoto, Japan; 2Helmholtz-Zentrum-Berlin (HZB), Berlin, Germany; 3Molekulare Botanik, Universität Ulm, Germany; 4IZMB – Institut für Zelluläre und Molekulare Botanik, Abt. Molekulare Evolution, University of Bonn, Bonn, Germany; 5University of Greifswald, Molecular Structural Biology, Greifswald, Germany
Seeing is believing: glycosylation in the crystal structure of human myeloperoxidase
Lucas Krawczyk1, Shubham Semwal1, Goedele Roos1, Pierre Van Antwerpen2, Julie Maria Jozefa Bouckaert1
1Centre National de REcherche Scientifique, Villeneuve d'Ascq, France; 2Laboratory of Pharmaceutical Chemistry and Analytical Platform, Faculty of Pharmacy, Université libre de Bruxelles, CP205/05, Boulevard du Triomphe, 1050 Brussels, Belgium
14-3-3 protein dependent modulation of ubiquitin ligase Nedd4-2
Pavel Pohl1,2, Tomáš Obšil1,3, Veronika Obšilová1
1Intitute of physiology, CAS, Vestec, Czech Republic; 2Second Faculty of Medicine, Charles University in Prague, Czech Republic; 3Dept. of Physical and Macromolecular Chemistry, Faculty of Science, Charles University in Prague, Czech Republic
Bacillithiol disulfide reductase Bdr - insight into a new type of FAD-containing NADPH-dependent oxidoreductases
Marta Hammerstad1, Ingvild Gudim1, Hans-Petter Hersleth1,2
1University of Oslo, Department of Biosciences, Oslo, Norway; 2University of Oslo, Department of Chemistry, Oslo, Norway
Exploring Polysaccharide lyases of PL-5 family through the lens of structure, function, and dynamics
Prerana Dash1,2, Rudresh Acharya1,2
1National Institution of science education and research, Bhubaneswar, India; 2Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400094, Maharashtra, India
Structural and functional characterization of a DNA binding protein of pIP501– a broad-host-range plasmid
Tamara Margot Isamel Berger1, Nina Gubensäk1, Walter Keller1, Verena Kohler2
1University of Graz, Graz, Austria; 2University of Stockholm, Stockholm, Sweden
First crystallographic study of a glutathione transferase from cyanobacteria
Eva Mocchetti1, Arnaud Hecker2, Benoît Guillot1, Sandrine Mathiot1, Franck Chauvat3, Corinne Cassier-Chauvat3, Claude Didierjean1
1CRM2, UL, CNRS, Nancy, France; 2IAM, UL, INRAE, Nancy, France; 3I2BC, UPS, CNRS, CEA, Paris-Saclay, France
Structural insights into the ferroxidase and iron sequestration mechanisms of ferritin from Caenorhabditis elegans
Tess R. Malcolm1, Sanjeedha Mohamed Mubarak1, Eric Hanssen2, Hamish G. Brown2, Gawain McColl3, Megan J. Maher1,4, Guy N.L. Jameson1
1Bio21 Molecular Science and Biotechnology Institute, Parkville, Australia; 2Ian Holmes Imaging Centre, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia; 3The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia; 4Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia
Precise Redox-dependent Structural Change of the plant-type Ferredoxin revealed by X-ray structures at 0.77 Å resolution, originated and propagating from the [2Fe-2S] cluster
Yusuke Ohnishi1,2, Hideki Tanaka1, Genji Kurisu1
1Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita city, Osaka 565-0871, Japan; 2School of Pharmaceutical Sciences, Wakayama Medical University, 25-1 Shichibancho, Wakayama city, Wakayama 640-8156, Japan
Crystal structure of carbohydrate esterase SmAcE1 from Sinorhizobium meliloti
Changsuk Oh1, Truc Kim1, T. Doohun Kim2, Kyeong Kyu Kim1
1Department of Precision Medicine, Sungkyunkwan University, Suwon, Korea, Republic of Korea; 2Department of Chemistry, College of Natural Science, Sookmyung Women's University, Seoul, 04310, Republic of Korea
Half way to hypusine. Structural characterization of human deoxyhypusine synthase.
Elżbieta Wątor, Piotr Wilk, Przemysław Grudnik
Małopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland
On substrate binding cavity of hyoscyamine 6β-hydroxylase from devil’s trumpet
Anna Kluza1, Beata Mrugala1, Katarzyna Kurpiewska1,2, Przemyslaw J Porebski1,3, Ewa Niedzialkowska1,3, Wladek Minor3, Manfred S Weiss4, Maksymilian Chruszcz5, Tomasz Borowski1
1Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Krakow, Poland; 2Department of Crystal Chemistry and Crystal Physics, Faculty of Chemistry, Jagiellonian University, Krakow, Poland; 3Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, USA; 4Macromolecular Crystallography, Helmholtz-Zentrum Berlin für Materialien und Energie, Berlin, Germany; 5Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA
Control of hydroxylation regioselectivity by hyoscyamine 6β-hydroxylase as revealed by crystallographic and QM/MM studies
Zuzanna Wojdyla, Anna Kluza, Tomasz Borowski
Jerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences, Krakow, Poland
Domain movements of NADPH–cytochrome P450 oxidoreductase (CPR) are required for the smooth electron transfer from CPR to heme–heme oxygenase-1 (HO-1) complex
Masakazu Sugishima1, Junichi Taira2, Mikuru Iijima3, Hideaki Sato1, Kei Wada4, Masato Noguchi1, Keiichi Fukuyama5, Mitsunori Takano3, Hiroshi Sakamoto2, Ken Yamamoto1
1Kurume University School of Medicine, Kurume, Japan; 2Kyushu Institute of Technology, Iizuka, Japan; 3Waseda University, Tokyo, Japan; 4University of Miyazaki, Miyazaki, Japan; 5Osaka University, Toyonaka, Japan
Conservation of a glutamate residue in ATP-citrate lyase and succinyl-CoA synthetase
Marie Elizabeth Fraser, Ji Huang
University of Calgary, Calgary, Canada
Monitoring the crystallization of two enzymes in real time by dynamic light-scattering
Kévin Rollet1,2, Raphaël de Wijn1, Sylvain Engilberge3, Alastair G. McEwen4, Oliver Hennig2, Heike Betet2, Mario Mörl2, François Riobé5, Olivier Maury5, Philippe Bénas1, Bernard Lorber1, Claude Sauter1
1Université de Strasbourg, ARN, CNRS UPR9002, IBMC, Strasbourg, France; 2Institute for Biochemistry, Leipzig University, Leipzig, Germany; 3Université Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France; 4Université de Strasbourg, IGBMC, CNRS UMR 7104, INSERM U 1258, Illkirch, France; 5Université Lyon 1, ENS Lyon, CNRS-UMR 5182, Lyon, France
Investigating The Structural Dynamics of the Water and Proton Channels Using snap-shots of Photosystem II
Mohamed Ibrahim
HU-Berlin, Berlin, Germany
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