XXV General Assembly and Congress of the
International Union of Crystallography - IUCr 2021
August 14 - 22, 2021 | Prague, Czech Republic
Conference Agenda
Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
Please note that all times are shown in the time zone of the conference. The current conference time is: 1st Nov 2024, 01:34:21am CET
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Session Overview |
| Session | ||
MS-66: Integrative structural biology: The next 50 years of the Protein Data Bank
Invited: Andrej Sali (USA), Fei Xu (China) | ||
| Session Abstract | ||
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Since 1971, the Protein Data Bank has provided open access to biomolecular structure data from crystallography, nuclear magnetic resonance spectroscopy, and electron microscopy. Over the next 50 years, structural biologists will shift their focus from single experimental technique studies to so-called integrative or hybrid methods investigations. The Integrative Structural Biology Microsymposium will showcase the power of combining complementary techniques of physical measurement and computational analysis to the problem of understanding the structure and function of large macromolecular machines important in fundamental biology, biomedical research, and bioenergy. The invited speakers will share their internationally-recognized expertise in macromolecular crystallography, cryo-electron microscopy, mass spectrometry, and computational structure modeling. Additional speakers, exemplifying the breadth of integrative structural biology research worldwide, will be selected from contributed abstracts. For all abstracts of the session as prepared for Acta Crystallographica see PDF in Introduction, or individual abstracts below. | ||
| Introduction | ||
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2:45pm - 2:50pm
Introduction to session 2:50pm - 3:20pm
Crystal structure of the first orphan GPCR ShanghaiTech University, Shanghai, China, People's Republic of 3:20pm - 3:50pm
From integrative structural biology to cell biology University of California, San Francisco, San Francisco, United States of America External Resource:
 3:50pm - 4:10pm
Crystal and Cryo-EM structures provide insight into how pro-neurodegenerative SARM1 is activated and cleave NAD+. 1Griffith University, Southport, Australia; 2University of Queensland, Brisbane, Australia; 3Evotec Ltd, Abingdon, Oxfordshire, UK; 4Disarm Therapeutics, a wholly-owned subsidiary of Eli Lilly & Co., Cambridge, USA External Resource:
4:10pm - 4:30pm
Structural studies of Cysteine Synthase Complex obtained from Klebsiella pneumoniae. 1Unité de Glycobiologie Structurale et Fonctionnelle, UMR 8576, CNRS, 50 Avenue Halley, 59650 Villeneuve d'Ascq, France; 2Biotechnology Department, Jaypee Institute of Information Technology (JIIT), A-10, sector-62 NOIDA, 201309, India External Resource:
4:30pm - 4:50pm
Crystal structure of a complex between the electron-transfer partners arsenite oxidase and cytochrome c552, from the arsenite respiring bacterium Rhizobium sp. NT-26. 1School of Chemistry and The Bio21 Instittute Molecular Sciences and Biotechnology Institute, The University of Melbourne, Parkville, 3052, Australia; 2Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, United Kingdom; 3Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia External Resource:
4:50pm - 5:10pm
Structural evidence for active site complementation and diverse oligomerization in two bacterial α-L-Fucosidases from the same organism 1Institute of Biotechnology of the Czech Academy of Sciences, 25250 Vestec, Czech Republic; 2University of Chemistry and Technology, 166 28 Prague, Czech Republic External Resource:
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