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Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

Daily Overview

Session

Parallel Session 3-2 Amyloids I

Time:

Tuesday, 25/Aug/2026:

11:00am - 1:00pm

Session Chair: Mei Hong

Location: Aspen

Lecture Hall in level 3, capacity 300

Presentations

11:00am - 11:24am

Solid-state NMR (SSNMR) analysis of structure and cross-seeding properties for amyloid-β (Aβ) and 𝛂-synuclein (𝛂Syn) fibrils and recent progress in SSNMR with ultra-high field and ultra-fast MAS

Ishii, Yoshitaka

Institute of Science Tokyo, Japan

11:24am - 11:36am

NMR Reveals Zn²⁺-Induced Dissociation of Transthyretin Tetramers into Monomers Drives Formation of Toxic, Seeding-Active Oligomers

Lim, Kwang Hun

East Carolina University, United States of America

11:36am - 11:48am

Novel PDS ESR-Based Blood Test for Early ALS Diagnosis Through SOD1 Structural Analysis

Nair, Carissa¹; Sinha Roy, Aritro¹; Lai, Alex²; Srivastava, Madhur^1,2

1: ACERT, United States of America; 2: Advanced Center for Electron Spin Resonance Research and Technology (ACERT), Inc.

11:48am - 12:12pm

Homomeric and heteromeric functional amyloids reveal structural control mechanisms in the programmed cell death pathway necroptosis

Sunde, Margie¹; Varghese, Nikhil¹; Williams, Brayden¹; Pham, Chi¹; Steain, Megan¹; He, Chengming²; McDermott, Ann²

1: School of Medical Sciences, The University of Sydney, Australia; 2: Department of Chemistry, Columbia University, New York

12:12pm - 12:24pm

Cryogenic DNP-enhanced solid-state NMR reveals how acetylation and amyloid context reshape the α-synuclein N-terminus

Lagasca, Dominique; Dumarieh, Rania; Allen, Carah; Krishna, Sakshi; Diaz, David; Ansari, Shoyab; Frederick, Kendra

University of Texas Southwestern Medical Center, United States of America

12:24pm - 12:36pm

PI3K SH3 Domain - Amyloid Model Protein (Un)folding investigated by NMR

Jaspert, Melinda^1,2; Gardon, Luis^1,2; Levorin, Leonardo^1,2; Kraus, Mirko^1,2; Gremer, Lothar^1,2; Neudecker, Philipp^1,2; Lakomek, Nils-Alexander^1,2; Heise, Henrike^1,2

1: Institute of Physical Biology, Heinrich-Heine-Universität Düsseldorf, Germany; 2: Institute of Biological Information Processing (IBI-7) and Jülich Center for Structural Biology (JuStruct), Forschungszentrum Jülich, Germany

12:36pm - 1:00pm

Aducanumab binding to Aβ1-42 Amyloid Fibrils

Palani, Ravi¹; Williams, Christopher²; Thacker, Dev³; Silvers, Robert⁴; Qian, Fang⁵; Weinreb, Paul⁵; Mueller, Leonard²; Linse, Sara³; Griffin, Robert¹

1: Massachusetts Institute of Technology, United States of America; 2: Department of Chemistry, University of California, Riverside; 3: Biochemistry and Structural Biology, Lund University, Lund, Sweden; 4: Biochemistry and Institute of Molecular Biophysics, Florida State University, Tallahassee, FL; 5: Biogen, Cambridge, MA