Microglial TREM2 receptor signaling shapes CA1 metabolism and synapses during development.

Erica Tagliatti, Genni Desiato, Sara Mancinelli, Matteo Bizzotto, Maria Cristina Gagliani, Rebeca Hernandez-Soto, Andrea Cugurra, Paola Poliseno, Matteo Miotto, Rafael Arguello, Fabia Filipello, Katia Cortese, Raffaella Morini, Elisa Faggiani, Simona Lodato, Michela Matteoli

Autophagic regulation of RNAs in the brain.

Lisa Gambarotto, Claudiane Guay, Vassiliki Nikoletopoulou

Rabphilin3A: From NMDA receptor synaptic retention to neurodevelopmental disorders

Marta Barzasi, Lisa Pavinato, Chiara Galizia, Monica Di Luca, Alfredo Brusco, Fabrizio Gardoni

Regulation of firing rate homeostasis by mutations associated with tauopathies and Alzheimer’s disease

Dema Hreaky, Antonella Ruggiero, Ilana Shapira, Inna Slutsky

Understanding sex differences in psychiatric disorders

Clara Unger

Active zone mechanisms underlying the functional differentiation of olfactory sensory neurons in Drosophila melanogaster

Namrata Acharya, Nadine Ehmann, Robert J. Kittel

Investigating the pathophysiological and molecular underpinnings of SynGAP Syndrome.

Taanisha Gupta, Judith von Sivers, Poornima Anantha Subramanian, Nils Rademacher, Stella-Amrei Kunde, Sarah Shoichet

Rab3 mediates cyclic AMP-dependent presynaptic plasticity and olfactory learning

Aishwarya Aravamudhan, Divya Sachidanandan, Achmed Mrestani, Jana Nerlich, Marius Lamberty, Natalie Hasenauer, Nadine Ehmann, Dennis Pauls, Teresa Seubert, Isabella Maiellaro, Mareike Selcho, Manfred Heckmann, Stefan Hallermann, Robert J. Kittel

Molecular mechanisms underlying the impairment of LTP in Fmr1 KO mice

Elisa Corti, Ramiro D. Almeida, Paulo Pinheiro, Carlos B. Duarte

Idiosyncrasy of antisense oligonucleotide targeting protein-coding gene embedded with non-coding RNA in vivo.

Md Hasan Ali, Savani Anbalagan

Structural dynamics of the pre-fusion form of SNARE proteins at the membrane interface: Recent insights by NMR spectroscopy

Tobias Stief, Katharina Vormann, Mirko Kraus, Reinhard Jahn, Angel Perez-Lara, Nils-Alexander Lakomek

Cell-adhesion proteins interplay with NMDA Receptors: implication for synaptic nanoarchitecture

Carlos Cação, Constança Ferreira, João Martins, Ana Luísa Carvalho, Joana Ferreira

Novel role for Piccolo in the secretion of astrocyte-derived perineuronal net components

Joanne Falck, Maryam Mohamaddokht, Frauke Ackermann

Pathophysiological consequences of middle domain DNM1 mutations

Marie Pronot, Michael Cousin

NMDA receptor autoantibodies primarily impair the extrasynaptic compartment

Zoë Jamet, Camille Mergaux, Morgane Meras, Delphine Bouchet, Jakob Kreye, Harald Prüss, Laurent Groc

Synaptic vesicle protein recycling in coupled exo-endocytosis in mammalian presynapses.

Vivek Belapurkar, Lou Bouit, Šárka Jelínková, David Perrais

Ultrastructure of dopaminergic synapses revealed with cryo-CLEM

Paul Lapios, Robin Anger, Rémi Fronzes, Etienne Herzog, David Perrais

Phosphoproteomic landscape of neuronal cytoskeletal regulators during chemically induced long-term depression

Rafaela Pedro Silva, Patricia Kreis, Till Mack, Marieluise Kirchner, Philipp Mertins, Britta J. Eickholt

Effects of Perturbed Sumoylation, Neddylation, and Ufmylation on Synaptic Transmission

Josefa Torres, Catarina Perdigao, Zehra Vural, Chunku Lee, Jeong Seop Rhee, Nils Brose, Marilyn Tirard

Non-canonical function of ADAM10 in presynaptic plasticity

Julia Bär, Tomas Fanutza, Christopher C. Reimann, Lisa Seipold, Maja Grohe, Janike R. Bolter, Flemming Delfs, Michael Bucher, Christine E . Gee, Michaela Schweizer, Paul Saftig, Marina Mikhaylova

Dissecting the role of the primary Synaptotagmin-1/SNARE complex interface on vesicle priming, spontaneous release clamping and Ca2+-triggered release

Estelle Toulme, Andrea Salazar-Lazaro, Klaudia Jaczynska, Thorsten Trimbuch, Jose Rizo, Christian Rosenmund

Characterization of EPS15 and EPS15R loss of function in brain

Jasmeet Kaur Shergill, Domenico Azarnia Tehran, Volker Haucke, Tanja Maritzen

NMDA Receptors Maintain Homeostatic Firing Rate Set Points in Hippocampal Circuits

Antonella Ruggiero, Leore R. Heim, Lee Susman, Dema Hreaky, Ilana Shapira, Maxim Katsenelson, Kobi Rosenblum, Inna Slutsky

Neuronal loss of the Alzheimer’s disease risk factor CALM perturbs synaptic plasticity and exacerbates amyloid pathology

Domenico Azarnia Tehran, Jasmeet Kaur Shergill, Volker Haucke, Tanja Maritzen

Ketamine increases glutamate release within minutes

Abdelmoneim Eshra, Noa Lipstein, Jana Nerlich, Stefan Hallermann

Membrane tension drives synaptic vesicle cycle through a conformational switch in the early endocytic machinery

Agata Witkowska, Tim Berneiser, Abdelmoneim Eshra, Svea Hohensee, Dmytro Puchkov, Stefan Hallermann, Volker Haucke

Divergent effects of PKA signaling on synaptic strength in glutamatergic and GABAergic cultured neurons

Astghik Abrahamyan, Christian Rosenmund, Melissa Herman

Oxidative stress dependent regulation of Ataxia Telangiectasia Mutated (ATM) kinase at the central nervous system synapse

Dimitra Ranti, Patricia Kreis, Janine Kirstein, Britta Eickholt

Towards a human IPSC-derived neuronal & glial network for translatable cognitive drug screenings

Larissa Breuer, Katarzyna Ludwik, Harald Stachelscheid, Camin Dean

The synapse specificity of schizophrenia genetic associations

Kamile Tamusauskaite, Nicholas E Clifton

Synaptic control of microtubule organisation in Parvalbumin interneurons

Daniela Hacker, Arie Maeve Brueckner, Sangmun Lee, Michael Bucher, Marina Mikhaylova, Eunjoon Kim

Sumoylation tunes actin dynamics in dendritic spines by unlocking the autoinhibitory interaction between the BAR and GAP domains of OPHN1

Alessia Seccia, Marta Busnelli, Cristina Guglielmetti, Marco Erreni, Marie Pronot, Fabrizia Claudia Guarnieri, Ninoska Polona Diestra, Chiara Scacchi, Marta Prieto, Martina Biagioni, Federica Baronchelli, Silvia Bassani, Davide Pozzi, Matteo Fossati, Maria Passafaro, Federico Forneris, Stèphane Martin, Michela Matteoli, Alessandra Folci

Type 1 transmembrane AMPA-receptor regulatory proteins are auxiliary subunits of kv7.2 voltage-gated potassium channels

Marina Ventura Rodrigues, Angela Sanches Inácio, Théo Bauberg, Maria Virginia Soldovieri, Telmo Leal, Sara Ribau, Luisa Amado, Luis Ribeiro, Nuno Beltrão, Gladys Caldeira, Laurent Groc, Joana Ferreira, Maurizio Taglialatela, Ana Luisa Carvalho

Modeling of Liquid-Liquid Phase Separation of the Synaptic Vesicle Cluster Using a Patchy Particle Model

Simon Dannenberg, Alena Taskina, Devika Magan, Stefan Klumpp

Dopaminergic modulation of Drd1a-Cre+ neurons and their local network activity in the murine medial prefrontal cortex

Mohammed Abuelem, Luis Fernando Messore, Zoltán Molnár, Edward Mann

CMTr cap-adjacent 2'-O-ribose mRNA methyltransferases are required for mRNA localization to synapses and reward learning

Matthias Soller, Yanjing Wu, Karthik Nallasivan, Nathan Archer, Zsuzsa Bodi, Daniel Hebenstreit, Scott Waddel, Rupert Fray, Irmgard Haussmann

Individual synaptic vesicles: molecular architecture

Uljana Kravcenko, Max Ruwolt, Jana Kroll, Artsemi Yushkevich, Julia Ruta, Rowaa Lotfy, Christian Rosenmund, Fan Liu, Mikhail Kudryashev

Synaptic Calcium Imaging as a high-throughput screen for Synapse Strengthening and Weakening Compounds

John Carl Begley, Paul Turko, Camin Dean

Activity-dependent interactions between neurons and microglia in the developing brain

Auguste Vadisiute, Anna Hoerder-Suabedissen, Zoltan Molnar

Characterization of the earliest thalamocortical interactions in the human fetal brain

Sara Bandiera, Faye McLeod, Eri Kawashita, Gavin Clowry, Zoltan Molnar

Unraveling the nanoscale organization and dynamics of endoplasmic reticulum in dendritic spines

Mariline Silva, Giovanna Coceano, Martina Damenti, Jonatan Alvelid, Chiara Sgattoni, Simone Ezendam, Ilaria Testa

An orexin-gated circuit in neocortical layer 6 regulates cortical excitability and anxiety behaviour

Luis Fernando Messore, Rajeevan Therpurakal, Jean-Philippe Dufour, Anna Hoerder-Suabedissen, Luiz Guidi, Kim Korrell, David Bannerman, Edward Mann, Zoltán Molnár

Role of glial pituicytes in neurohypophyseal synaptic morphogenesis

Naveen Nedunchezhian, Savani Anbalagan

Biochemical and neurophysiological effects of TIMM50 deficiency in neurons and fibroblasts

Eyal Paz, Sahil Jain, Irit Gottfried, Orna Staretz-Chacham, Muhammad Mahajnah, Pritha Bagchi, Nicholas T. Seyfried, Uri Ashery, Abdussalam Azem

MNK1 and MNK2 in translational regulation and synaptic function

Rosalba Olga Proce, Maria Steinecker, Erika Uddström, Lucie Hortmann, Hanna Hörnberg

Phosphorylation of PLPPR3 membrane proteins as signaling integrator at neuronal synapses

Cristina Kroon, Britta J. Eickholt

Linking Synaptic Mitochondrial Dysfunction and Dopamine Oxidation: A Parkinson's Perspective?

Leonie Heger, Lena Burbulla

Investigate the molecular mechanisms underlying autism-associated behavioral phenotypes

Rosalba Olga Proce, Hanna Hörnberg

Touch sensation requires the mechanically gated ion channel ELKIN1

Sampurna Chakrabarti, Jasmin Klich, Mohammed Khallaf, Amy Hulme, Zuzanna Baran, Anuar Makhmut, Rocio Finol-Urdaneta, Fabian Coscia, Mirella Dottori, Gary Lewin

Exploring ADAMTS-5 Inhibition: A Novel Drug Repurposing Strategy Against ECM Remodelling in Neural Pathologies

Anjali Singh, Pasent Zaki, Alexander Dityatev, Stepan Aleshin

All-in-one cryoCLEM probes

Sylvestre Bachollet, Daniel Roderer, Johannes Broichhagen

Fluorophores with optimized chemical and photophysical properties for smFRET

Blaise Gatin-Fraudet, Sigrid Milles, Johannes Broichhagen

Identifying synaptic substrates of ESCRT-dependent degradation

Devaraj Thittayil Puthusssery, Marijn Kuijpers

Functional characterization of the disease-associated scaffold protein CNKSR2

Poornima Anantha Subramanian, Hanna Zieger, Benno Kuropka, Taanisha Gupta, Judith von Sivers, Stella-Amrei Kunde, Nils Rademacher, Sarah Shoichet

Secretory autophagosomes shape the synaptic surfaceome

Erin Wosnitzka, Devanarayanan Siva Sankar, Angeliki Kolaxi, Irina Kolotueva, Christel Genoud, Joern Dengjel, Vassiliki Nikoletopoulou

Shedding Light on Presynaptic Plasticity: Synaptic plasticity at commissural projection synapses in Hippocampus CA1

Lukas Alfred Faiss, Silvia Oldani, Jörg Breustedt, Dietmar Schmitz, Benjamin Rost

Distribution of IP3- and Ryanodine- receptors in somas and dendritic spines of hippocampal neurons through 8-Fold Expansion Microscopy

Ignacio Vega-Vásquez, Christian Werner, Markus Sauer

Investigating ultrastructural and molecular correlates of short-term facilitation at hippocampal mossy fibre synapses

Inés HOJAS GARCIA PLAZA, Francisco José LÓPEZ-MURCIA, Manuela SCHWARK, Cristian BOGACIU, Silvio Rizzoli, Holger TASCHENBERGER, Nils BROSE, Cordelia IMIG, Benjamin COOPER

MSK1 absence hinders BDNF-dependent striatal neurodevelopment and leads to schizophrenia symptomps

Natalia Varela-Andrés, Alejandro Cebrián-León, Carlos Hernández-del Caño, Inés S. Fernández del Campo, Sandra García-Losada, Noelia Martín-Ávila, Juan Carlos Arévalo, Miguel A. Merchán, Manuel Sánchez-Martín, Rubén Deogracias

Contributions of APP metabolites in early Alzheimer's dysfunction

Akshay Kapadia, Anne-Sophie Hafner

The Role of the Munc13-1 C1 domain in the regulation of SV priming and short-term plasticity at a large glutamatergic synapse of the mammalian brainstem

Mrinalini Ranjan, Kun-Han Lin, Erwin Neher, Noa Lipstein, Nils Brose, Holger Taschenberger

Spatial Regulation of Neuronal Metabolism by Autophagy

Lotte Ickert, Natalia Kononenko

Deciphering the molecular determinants of ketamine-elicited behavioral changes on NMDA receptors

Floriane Uyttersprot

Distinct functions of Synaptotagmin-1 and -7 in neurotransmitter release

Sina Tamara Zobel, Boris Bouazza-Arostegui, Thorsten Trimbuch, Christian Rosenmund

Unravelling the age-related changes in the synaptic interactome with crosslinking mass spectrometry

Anjalinna Kugathas, Domenico Azarnia Tehran, Fan Liu

Define the synaptic remodeling during cycle of hibernation in hamster by cross-linking mass spectrometry

Mei Wu, Domenico Azarnia Tehran, Cong Wang, Fan Liu

Comprehensive delineation and precision medicine of GRIN-related neurodevelopmental disorders, a primary disturbance of the NMDA receptor

Xavier Altafaj, Ana Santos-Gómez, Sílvia Locubiche-Serra, David Soto, Natalia Juliá-Palacios, Àngels García-Cazorla, Mireia Olivella

COMPUTATIONAL TOOLS TOWARDS GRIN VARIANTS STRATIFICATION

Mireia Olivella, Ana Santos-Gómez, Adrián García-Recio, Federico Miguez-Cabello, Xavier Altafaj

Role of Synapsin in Hippocampal Mossy Fiber Presynaptic Plasticity

Felicitas Brüntgens, Laura Moreno Velasquez, Alexander Stumpf, Daniel Parthier, Dragomir Milovanovic, Fabio Benfenati, Jörg Breustedt, Dietmar Schmitz, Marta Orlando

Investigating presynaptic nanoarchitecture using proximity labeling approaches

Mareike Lohse, Siqi Sun, Olaf Jahn, Nils Brose, Noa Lipstein

Gradual reduction of Munc13-1 levels after synaptogenesis

Moritz Boll, Noa Lipstein

Characterization of axonal precursor organelles for presynaptic biogenesis

Max Thomas Lucht