Conference Agenda

COMPUTATIONAL ANALYSIS OF VENTRICULAR EXPANDER TO TREAT DIASTOLIC DYSFUNCTION

J. Weissmann¹, I. Benoliel¹, C. H. Yap², G. Marom¹

¹Tel Aviv University, Israel; ²Imperial College London, United Kingdom

PATIENT-SPECIFIC COMBINED FEA-FSI METHODOLOGY TO MODEL THE TEVAR PROCEDURE

A. Ramella¹, F. Migliavacca¹, J. F. Rodriguez Matas¹, T. J. Mandigers², D. Bissacco², M. Domanin^2,3, S. Trimarchi^2,3, G. Luraghi¹

¹Politecnico di Milano, Italy; ²Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, italy; ³Università degli Studi di Milano, Italy

MODELING IN-VITRO MATURATION OF TISSUE-ENGINEERED BIOHYBRID HEART VALVE IMPLANTS

M. Sesa¹, H. Holthusen¹, C. Böhm², S. Jockenhövel², S. Reese¹

¹Institute of Applied Mechanics, RWTH Aachen University, Aachen, Germany; ²Biohybrid & Medical Textile (BioTex), Institute of Applied Medical Engineering, RWTH Aachen University, Aachen, Germany

A MULTISCALE MODEL OF IN-STENT RESTENOSIS IN CORONARY ARTERIES INTEGRATING DRUG KINETICS WITH CELL DYNAMICS

A. Corti¹, A. McQueen², F. Migliavacca¹, C. Chiastra³, S. McGinty²

¹LaBS, Department of Chemistry, Materials and Chemical Engineering “Giulio Natta”, Politecnico di Milano, Milan, Italy; ²Division of Biomedical Engineering, University of Glasgow, Glasgow, UK; ³PoliToBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy

IN SILICO MODELLING OF ENDOVASCULAR DRUG DELIVERY FROM DRUG-COATED BALLOONS

A. Fensterseifer Schmidt¹, K. Oldroyd², A. Aggarwal³, S. McGinty^1,3

¹Division of Biomedical Engineering, University of Glasgow, United Kingdom; ²Cardiovascular & Metabolic Health, University of Glasgow, United Kingdom; ³Glasgow Computational Engineering Centre, University of Glasgow

SEMIRIGID SPINAL FIXATION TECHNIQUES COULD HELP PREVENT PROXIMAL JUNCTIONAL KYPHOSIS – A FINITE ELEMENT STUDY

M. Turbucz^1,2, A. Pokorni^1,2, A. Lazary³, P. Eltes^1,3

¹In Silico Biomechanics Laboratory, National Center for Spinal Disorders, Budapest, Hungary; ²Semmelweis University, Budapest, Hungary; ³National Center for Spinal Disorders, Budapest, Hungary

BIOMECHANICAL ALTERATIONS AFTER SPINAL FUSION TREATMENT AND THEIR RELATION TO CAGE SUBSIDENCE

S. Ananth Swaminathan¹, L. Becker², N. Taheri², M. Pumberger², H. Schmidt¹, S. Checa¹

¹Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Germany; ²Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Germany

AUTOMATIC SEGMENTATION OF THE SPINE FROM MR AND SYNTHETIC CT IMAGES

J. Kok¹, Y. Shcherbakova², T. Schlösser², P. Seevinck^2,3, T. van der Velden^2,3, R. Castelein², K. Ito^1,2, B. van Rietbergen¹

¹Eindhoven University of Technology, Netherlands, The; ²University Medical Center Utrecht, Netherlands, The; ³MRIguidance BV, Netherlands, The

BIOMECHANICAL EFFECT OF LUMBAR SPINE DECOMPRESSION: COMPARISON OF TWO DIFFERENT SURGICAL TECHNIQUES

S. Montanari¹, S. Di Santo¹, E. Serchi², A. Conti², L. Cristofolini¹

¹Alma Mater Studiorum - Università di Bologna, Italy; ²IRRCS Istituto delle Scienze Neurologiche, Bellaria Hospital (BO), Italy

INFLUENCE OF CERVICAL TOTAL DISC REPLACEMENT ON MOTION IN THE TARGET SEGMENTS AND ADJACENT SEGMENTS

M. Vogt¹, C. Mehren², H.-J. Wilke¹

¹Institute of Orthopaedic Research and Biomechanics, University of Ulm, Germany; ²Spine Center, Schoen Clinic Munich-Harlaching, Munich, Germany

A NEW OPEN-SOURCE WORKFLOW FOR MULTISCALE MODELING OF HEPATIC PERFUSION

M. A. CHETOUI, M. MORVAN, P. BEAUREPAIRE, A. VACAVANT

Clermont Auvergne University, Clermont Auvergne INP, CNRS, Institut Pascal, France

PRE-OPERATIVE RISK ASSESSMENT OF PARAVALVULAR LEAKAGE USING A COMPUTATIONAL TAVI DEPLOYMENT MODEL

M. Spanjaards¹, R. Ubachs¹, V. Lavezzo¹, O. Van der Sluis^1,2

¹Philips Research, Netherlands, The; ²Eindhoven University of Technology

3D STATISTICAL SHAPE MODELING FOR CLASSIFICATION OF TREATMENT EFFECTS ON OSTEOPOROTIC MOUSE BONE GEOMETRY

S. Moraiti^1,4, V. S. Cheong^3,4,5, E. Dall'Ara^2,4, V. Kadirkamanathan^3,4, P. Bhattacharya^1,4

¹Dept. of Mechanical Engineering, University of Sheffield, UK; ²Dept. of Oncology and Metabolism, University of Sheffield, UK; ³Dept. of Automatic Control and Systems Engineering, University of Sheffield, UK; ⁴Insigneo Institute for in silico Medicine, Sheffield, UK; ⁵Singapore-ETH Centre

EXPERIMENT AND SIMULATION STUDY OF THE ENERGY ABSORBTION IN BIOMIMETIC SCAFFOLD LATTICES

M. Vafaeefar, K. M. Moerman, T. J. Vaughan

University of Galway, Ireland

PRE-CONDITIONING OF TRAINING DATA FOR GAUSSIAN PROCESS REGRESSION ENABLED OPTIMISATION OF THE NEOVAD

L. D. Nissim¹, S. Karnik², P. A. Smith², Y. Wang², K. H. Fraser¹

¹University of Bath, United Kingdom; ²Texas Heart Institute, United States of America

FRACTURE MANAGEMENT STRATEGIES INFLUENCE THE FRACTURE HEMATOMA PROTEOME AFTER MULTIPLE TRAUMA.

C. Kuik¹, R. V. M. Groven^2,3, J. Greven⁴, Ü. Mert⁴, F. G. Bouwman⁵, M. Huber-Lang⁶, F. Hildebrand⁴, T. Blokhuis³, M. van Griensven², B. Cillero-Pastor^1,2

¹Maastricht Multimodal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University, Maastricht, The Netherlands; ²Department of Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands; ³Division of Trauma Surgery, Department of Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands; ⁴Department of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany.; ⁵NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands.; ⁶Institute of Clinical and Experimental Trauma Immunology, University Hospital Ulm, Ulm, Germany.

COMPUTATIONAL MODELING FOR EVALUATING THE EFFECTIVENESS OF PROTECTIVE PLATES IN NON-PENETRATING BALLISTIC IMPACTS

M. Lustig¹, Y. Epstein², A. Gefen¹

¹Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel; ²Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

A MUSCLE MODEL FOR INJURY SIMULATION

M. Millard^1,2, F. Kempter², J. Fehr², N. Stutzig¹, T. Siebert¹

¹Institute of Sport Science, University of Stuttgart, Allmandring 28, 70569 Stuttgart, Germany; ²Institute of Engineering and Computational Mechanics, Pfaffenwaldring 9, 70569 Stuttgart, Germany

CERVICAL MUSCLE REFLEXES DURING LATERAL ACCELERATIONS

M. Millard^1,2, S. Hunger¹, L. Bross¹, J. Fehr², C. Holzapfel³, N. Stutzig¹, T. Siebert¹

¹Institute of Sport Science, University of Stuttgart, Allmandring 28, 70569 Stuttgart, Germany; ²Institute of Engineering and Computational Mechanics, Pfaffenwaldring 9, 70569 Stuttgart, Germany; ³FKFS, Pfaffenwaldring 12, 70569 Stuttgart, Germany

DEVELOPMENT OF A HEAD ACCELERATION EVENT CLASSIFICATION ALGORITHM FOR FEMALE RUGBY UNION

D. R. L. Powell^1,2, F. J. Petrie², P. D. Docherty^3,4, H. Arora¹, E. M. P. Williams²

¹ZCCE, Faculty of Science and Engineering, Swansea University, Wales, UK; ²2Applied Sports, Technology, Exercise and Medicine Research Centre (A-STEM), Swansea University, Wales, UK; ³3Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand; ⁴Institute for Technical Medicine (ITeM), Furtwangen University, Villingen Schwenningen, Germany

THE REASONS FOR DIFFERENCES BETWEEN 2D AND 3D ECHOCARDIOGRAPHY STRAIN MEASUREMENTS

M. Ren¹, W. X. Chan², L. Green², A. Armstrong³, A. Tulzer⁴, G. Tulzer⁴, M. L Buist¹, C. H. Yap²

¹Dept of Biomedical Engineering, National University of Singapore, Singapore; ²Dept of Bioengineering, Imperial College London, London, UK; ³The Heart Center, Nationwide Children’s Hospital, Columbus, Ohio, USA; ⁴Dept of Pediatric Cardiology, Kepler University Hospital, Linz, Austria

INVESTIGATION OF SUBCLINICAL HEMOLYSIS IN AORTIC VALVE STENOSIS USING 4D FLOW MRI-BASED CFD SIMULATIONS

T. Wang¹, C. Quast², F. Bönner², M. Kelm^2,3, U. Steinseifer¹, M. Neidlin¹

¹Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty, RWTH Aachen University, Aachen, Germany; ²Department of Cardiology, Pulmonary Diseases and Vascular Medicine, Heinrich-Heine University, Düsseldorf, Germany; ³CARID, Cardiovascular Research Institute Düsseldorf, Heinrich-Heine University, Düsseldorf, Germany

THE IMPACT OF A LIMITED FIELD-OF-VIEW ON COMPUTED HEMODYNAMICS IN ABDOMINAL AORTIC ANEURYSMS

J. Fonken^1,2, E. Maas^1,2, A. Nievergeld^1,2, M. van Sambeek^1,2, F. van de Vosse¹, R. Lopata¹

¹Eindhoven University of Technology, The Netherlands; ²Catharina Hospital Eindhoven, the Netherlands

A NOVEL APPROACH FOR EXAMINING MOTION AND DEFORMATION OF LEFT VENTRICLE: FINITE ELEMENT ANALYSIS OF 3D ECHOCARDIOGRAPHY DATA

B. Cansiz, K. Sveric, A. Linke, M. Kaliske

Technishce Universität Dresden, Germany

PERSONALIZED FINITE ELEMENT ANALYSIS OF LARGE ABDOMINAL AORTIC ANEURYSMS USING MULTI-PERSPECTIVE 3D+T ULTRASOUND

E. J. Maas^1,2, T. Timmer¹, A. H. M. Nievergeld^1,2, J. H. C. Fonken^1,2, R. G. P. Lopata¹, M. R. H. M. van Sambeek^1,2

¹Eindhoven University of Technology, The Netherlands; ²Catharina Hospital Eindhoven, The Netherlands

PATIENT SPECIFIC NUMERICAL STUDY OF AN INTRACRANIAL ANEURYSM MECHANICAL CHARACTERISATION DEVICE

J. Raviol¹, G. Plet¹, M. Ohta², H. Magoariec¹, C. Pailler-Mattei^1,3

¹Laboratoire de Tribologie et Dynamique des Systèmes, CNRS UMR 5513, Université de Lyon, École Centrale de Lyon, France; ²Institute of Fluid Science, Tohoku University, Sendai, Japan; ³Université de Lyon, Université Claude Bernard Lyon 1, ISPB- Faculté de Pharmacie

AN INVERSE FINITE ELEMENT ANALYSIS FOR THE DETERMINATION OF THE IN VIVO BIOMECHANICAL PROPERTIES OF THE BLADDER

E. Silva¹, S. Brandão², T. Mascarenhas³, R. N. Jorge⁴

¹LAETA, INEGI, Portugal; ²Department of Radiology, Centro Hospitalar de São João-EPE, Faculty of Medicine, University of Porto, Portugal; ³Department of Gynecology and Obstetrics, Centro Hospitalar de São João-EPE, Faculty of Medicine, University of Porto, Portugal; ⁴LAETA, INEGI, Faculty of Engineering, University of Porto, Portugal

PATIENT-SPECIFIC MODELLING OF THE TRAPEZIOMETACARPAL JOINT LIGAMENTS

T. Valerio, J.-L. Milan, B. Goislard de Monsabert, L. Vigouroux

Aix-Marseille University, France

THE INFLUENCE OF TWISTED STRUCTURES OF THE ACHILLES TENDON ON STRAIN DISTRIBUTION - PATIENT-SPECIFIC FE STUDY

A. Funaro¹, V. Shim², I. Mylle¹, B. Vanwanseele¹

¹KU Leuven, Belgium; ²University of Auckland, New Zealand

A COMPREHENSIVE BIOMECHANICAL ANALYSIS OF HEMIPELVIC CUSTOM-MADE RECONSTRUCTIONS IN THE LONG-TERM FOLLOW-UP

E. Schileo¹, G. Fraterrigo^1,2, G. Valente¹, M. De Paolis³, D. M. Donati¹, F. Taddei¹

¹IRCCS Istituto Ortopedico Rizzoli, Italy; ²Politecnico di Torino,Torino, Italy; ³IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy

VALIDATION OF A DIGITAL TWIN TO QUANTIFY THE LEVEL OF MOTOR CONTROL SUBOPTIMALITY IN PATIENTS

G. Davico^1,2, D. Princelle^1,2, M. Viceconti^1,2

¹Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Italy; ²Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Italy

KNEE FLEXION ANGLE ESTIMATION BASED ON FUNCTIONALLY INSTEAD OF ANATOMICALLY DEFINED COORDINATE SYSTEMS

J. De Schutter¹, A. Verduyn¹, M. Vochten¹, E. Aertbeliën¹, A. Ancillao²

¹KU Leuven & Flanders Make, Belgium; ²TU Wien, Austria

EVALUATION OF MARKERLESS MOTION CAPTURE USING MUSKULOSKELETAL MODELS

S. Auer¹, L. Gschoßmann¹, S. Dendorfer^1,2

¹Laboratory for Biomechanics, OTH Regensburg, Germany; ²Regensburg Center of Health Sciences and Technology, Germany

A FRAME ORIENTATION OPTIMISATION METHOD TO ENABLE VALID KINEMATIC COMPARISONS: ASSESSING IMU-BASED KNEE KINEMATICS

A. Ortigas Vásquez^1,2, W. R. Taylor³, A. Maas^1,2, M. Woiczinski², T. M. Grupp^1,2, A. Sauer^1,2

¹Research and Development, Aesculap AG, Tuttlingen, Germany; ²Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Centre Munich (MUM), Campus Grosshadern, Ludwig Maximilians University Munich, Munich, Germany; ³Laboratory for Movement Biomechanics, ETH Zurich, Switzerland

MIMU BASED POSTUROGRAPHY: COMPARISON OF METHODS

A. Guiotto¹, E. Pegolo¹, Z. Sawacha^1,2

¹Dept of Information Engineering, University of Padova, Italy; ²Dept of Medicine, University of Padova, Italy

BIOMECHANICAL ANALYSIS OF KNEE JOINT FLEXION IN HEALTHY, CRUCIATE DEFICIENT AND CRUCIATE SUBSTITUTE CONDITIONS

E. Bori¹, S. Todros², M. Favaron¹, P. Pavan², B. Innocenti¹

¹BEAMS Department, ULB - Université Libre de Bruxelles, Brussels, Belgium; ²Department of Industrial Engineering, University of Padova, Padua, Italy

CAN OSTEOARTHRITIS AFTER ACL RECONSTRUCTION BE EXPLAINED BY (ALTERING) GRAFT MECHANICAL PROPERTIES?

J. Spierings, M. van den Hengel, B. van Rietbergen, K. Ito, J. Foolen

Eindhoven University of Technology, Netherlands, The

LENGTH CHANGES OF THE MEDIAL PATELLOFEMORAL LIGAMENT DURING IN VIVO KNEE MOTION: A DYNAMIC EVALUATION.

M. R. Boot¹, S. A. W. van de Groes², H. Dunning¹, E. Tanck¹, D. Janssen¹

¹Orthopaedic Research Laboratory, Radboud University Medical Center, Nijmegen, The Netherlands; ²Department of Orthopaedics, Radboud University Medical Center, Nijmegen, The Netherlands

TIBIOFEMORAL GAPS OF HUMAN CADAVERIC KNEES BEFORE AND AFTER SACRIFICING BOTH CRUCIATE LIGAMENTS

S. A. Brendle^1,2, S. Krüger¹, J. Grifka³, P. E. Müller², T. M. Grupp^1,2

¹Research and Development, Aesculap AG, Tuttlingen, Germany; ²Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, LMU Munich, Munich, Germany; ³Department of Orthopaedics, Asklepios Klinikum, Bad Abbach, Germany

CONSEQUENCES OF LIMITING ELECTROMYOGRAPHY AND GROUND REACTION FORCES ON MODELLED ANTERIOR CRUCIATE LIGAMENT FORCES

A. Nasseri¹, R. Akhundov¹, A. Bryant², D. Lloyd¹, D. J. Saxby¹

¹Griffith Centre of Biomedical and Rehabilitation Engineering (GCORE), Menzies Health Institute Queensland, Griffith University, Australia; ²Centre for Health, Exercise & Sports Medicine, University of Melbourne, Australia

FROM MECHANOBIOLOGY OF AORTIC SMOOTH MUSCLE CELLS TO IMPROVED PROGNOSIS OF THORACIC AORTIC ANEURYSMS

S. Avril

Mines Saint-Etienne, France

THE IMPACT OF 4D-FLOW MRI-DERIVED INLET CONDITIONS IN FLOW SIMULATIONS OF ANEURYSMAL TYPE-B AORTIC DISSECTION

C. Stokes^1,2, D. Ahmed³, N. Lind⁴, F. Haupt⁴, D. Becker⁵, V. Muthurangu⁶, H. von Tengg-Kobligk⁴, G. Papadakis³, S. Balabani^1,2, V. Diaz-Zuccarini^1,2

¹Department of Mechanical Engineering, University College London, UK; ²Wellcome-EPSRC Centre for Interventional Surgical Sciences, London, UK; ³Department of Aeronautics, Imperial College London, UK; ⁴Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern, Switzerland; ⁵Centre for Translational Cardiovascular Imaging, University College London; ⁶Clinic of Vascular Surgery, Inselspital, University of Bern, Switzerland

MERGING 4D ULTRASOUND AND MODIFIED VIRTUAL FIELDS METHOD TO REGIONALLY CHARACTERIZE ABDOMINAL AORTIC ANEURYSMS

M. Thirugnanasambandam^1,2, E. J Maas^1,2, A. H M Nievergeld^1,2, M. R H M van Sambeek^1,2, S. Avril³, R. G P Lopata¹

¹Eindhoven University of Technology, the Netherlands; ²Catharina Hospital Eindhoven, the Netherlands; ³Ecole des MINES St. Etienne, France

ANALYZING ABDOMINAL AORTIC ANEURYSM VESSEL, LUMEN AND THROMBUS GROWTH USING 3D+T ULTRASOUND

A. Nievergeld^1,2, E. Maas^1,2, J. Fonken^1,2, M. van Sambeek², R. Lopata¹

¹Eindhoven University of Technology, Netherlands, The; ²Catharina Hospital Eindhoven, Netherlands

RISK ASSESSMENT OF ASCENDING AORTIC ANEURYSMS USING PROBABILISTIC MATERIAL PARAMETERS AND IN VIVO THICKNESS

S. Dreesen, K. Vander Linden, N. Famaey

KU Leuven, Belgium

3D BIOPRINTED SCAFFOLD WITH CONTROLLED RELEASE OF MESENCHYMAL STEM SECRETOME FOR BONE REGENERATION

M. Conti

University of Pavia, Italy

PARACRINE EFFECTS OF MACROPHAGE PHENOTYPE ON TENDON TISSUE REMODELING

H. F. M. Brouwer^1,2, A. Mansoor^1,2, L. Verberne^1,2, C. V. C. Bouten^1,2, A. I. P. M. Smits^1,2, J. Foolen^1,2

¹Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; ²ICMS, Eindhoven University of Technology, The Netherlands

VARIABLE OXYGEN CONDITIONS AND CARDIOMYOCYTE STRUCTURE AND FUNCTION IN NOVEL IMMUNO-HEART CHIP

A. A. Schmidt^1,2, L. David^1,2, W. Liu^1,2, A. Grosberg^1,2

¹Dept. of Biomedical Engineering, University of California, Irvine, Irvine, CA, United States of America; ²UCI Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center, UCI, Irvine, CA, United States of America

THE EFFECTS OF ANTI-OSTEOPOROTIC DRUGS ON A 3D DYNAMIC IN VITRO HUMAN BONE REMODELIG MODEL

B. W. M. de Wildt, K. de Graaf, K. Ito, S. Hofmann

Orthopaedic Biomechanics, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, Eindhoven, The Netherlands.

MINI INVASIVE IMAGING WINDOW TO GUIDE AND IMAGE FOREIGN BODY REACTIONS IN VIVO

C. Conci¹, L. Sironi², E. Jacchetti¹, D. Panzeri², D. Inverso², R. Martínez³, G. Cerullo⁴, R. Osellame³, M. Collini², G. Chirico², M. Raimondi¹

¹Politecnico di Milano, Dip Chimica Mat e Ing. Chimica G.Natta, Italy; ²Univ. di Milano-Bicocca, Dipartimento di Fisica, Milan, Italy; ³Istituto di Fotonica e Nanotecnologie (IFN)-CNR; ⁴Dipartimento di Fisica, Politecnico di Milano, Milan, Italy

SCREW LENGTH IMPACT ON BONE STRAIN FOR A PROXIMAL HUMERAL PLATE VIA A NEURAL NETWORK MODEL

D. Mini, K. Reynolds, M. Taylor

Medical Device Research Institute, College of Science & Engineering, Flinders University, Australia

VALIDATED, HIGH-RESOLUTION, NON-LINEAR, EXPLICIT FINITE ELEMENT MODELS FOR SIMULATING SCREW PUSH-IN STRENGTH

Y. Zhou¹, B. Helgason², S. J. Ferguson², C. Persson¹

¹Uppsala University, Sweden; ²ETH Zürich, Switzerland

FRACTURE ANGLES INFLUENCE HEALING IN FULLY REDUCED DISTAL FEMUR FRACTURES TREATED WITH LOCKING PLATES

X. Yu¹, A. H. Simpson², P. Pankaj¹

¹Institute for Bioengineering, School of Engineering, The University of Edinburgh, UK; ²Department of Orthopaedics and Trauma, Edinburgh Medical School, The University of Edinburgh, UK

A FULLY COUPLED COMPUTATIONAL FRAMEWORK FOR BONE FRACTURE REPAIR IN THE PRESENCE OF BIOABSORBABLE MAGNESIUM FIXATION DEVICES

C. R. Quinn

University of Galway, Ireland

FEASIBILITY OF BONE-LIKE PROSTHESES USING A PARAMETRIC TRABECULAR BONE MODEL AND DEM SIMULATIONS

N. ROGALSKI¹, S. LAPORTE¹, I. IORDANOFF², J. GIRARDOT², C. CLUZEL³

¹Arts et Métiers, Université Sorbonne Paris Nord, IBHGC, Paris, France; ²Arts et Métiers, Université de Bordeaux, CNRS, Bordeaux INP, INRAE, I2M Bordeaux, France; ³Université Paris-Saclay, Centrale Supélec, ENS Paris-Saclay, CNRS, LMPS, Gif-Sur-Yvette, France

TRABECULAR TORSION CAN LOCALISE FRACTURE IN VITRO IN TRUSS FINITE ELEMENT MODELS

M. Pani¹, C. Ruiz Wills², S. Tassani²

¹SMDE, University of Portsmouth, United Kingdom; ²BCN MedTech, DTIC, Universidad Pompeu Fabra, Barcelona, Spain

PREDICTION OF OVERLOADING FAILURE OF OSTEOSYNTHESIS PLATES USING VALIDATED FINITE ELEMENT SIMULATIONS

D. Mischler¹, A. Valenti^1,2, P. Varga¹

¹AO Research Institute Davos, Switzerland; ²University of Bern, Switzerland

TOWARDS UNBIASED AND ACCURATE SIMULATIONS OF SCREW-BONE CONSTRUCTS WITH HOMOGENIZED FE MODELS

A. Synek¹, L. Ortner¹, D. Pahr^1,2

¹TU Wien, Austria; ²Karl Landsteiner University of Health Sciences, Austria

SIMPLIFIED SCREW-BONE INTERFACE MODELS FOR COMPUTATIONALLY EFFICIENT µFE SIMULATIONS

P. Stefanek¹, D. H. Pahr^1,2, A. Synek¹

¹TU Vienna, Austria; ²Karl Landsteiner University of Health Sciences, Austria

FE ANALYSIS OF AN EXTERNAL STABILIZER APPLIED IN TREATMENT OF THE PROXIMAL PHALANX FRACTURE IN HORSES

M. Pawlikowski¹, K. Jankowski¹, B. Turek²

¹Warsaw University of Technology, Poland; ²Warsaw University of Life Sciences, Poland

DETERMINATION OF THE INTERNAL LOADS OF THE PROXIMAL PHALANX DURING REHABILITATION EXERCISES

P. Schwarzenberg¹, T. Colding-Rasmussen², D. J. Hutchinson³, J. San Jacinto Garcia³, V. Granskog⁴, T. Pastor¹, T. Weis², M. Malkoch³, C. Wong², P. Varga¹

¹AO Research Institute, Switzerland; ²RegionH, Denmark; ³KTH Royal Institute of Technology, Sweden; ⁴Biomedical Bonding AB, Sweden

DEVELOPMENT OF 3D PRINTED PATIENT-SPECIFIC SCAPHOID IMPLANT TO ACHIEVE CUSTOMISED SCAPHOID REPLACEMENT

S. L. Teng¹, F. Li¹, K. Y. Chung², A. Y. H. Chin¹, Y. R. Wong¹

¹Singapore General Hospital, Singapore; ²Temsek Polytechnic, Singapore

STRAINS AND FAILURE MODES IN HUMAN METASTATIC VERTEBRAE

M. Palanca¹, G. Cavazzoni¹, L. Cristofolini¹, E. Dall'Ara^2,3

¹Dept of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Italy; ²Dept of Oncology and Metabolism, The University of Sheffield, UK; ³INSIGNEO Institute for in silico medicine, The University of Sheffield, UK

VALIDATION OF HOMOGENIZED FINITE ELEMENT MODELS OF HUMAN METASTATIC VERTEBRAE USING DIGITAL VOLUME CORRELATION

C. Garavelli^1,2, A. Aldieri^2,3, M. Palanca¹, E. Dall'Ara^4,5, M. Viceconti^1,2

¹Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Italy; ²Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; ³PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino, Italy; ⁴Department of Oncology and Metabolism, University of Sheffield, UK; ⁵INSIGNEO Institute for In Silico Medicine, University of Sheffield, UK

INTERVERTEBRAL DISC IMPACT ON STRESSES IN GROWTHPLATES OF AN ADOLESCENT IDIOPATHIC SCOLIOTIC SPINE FOLLOWING UNILATERAL MUSCLE WEAKENING

Z. Kamal¹, R. kakavad², A. Komeili²

¹University Medical Center Groningen, Netherlands, The; ²University of Calgary, Calgary, AB, Canada

SPINAL AXIAL TORQUE IN ADOLESCENT IDIOPATHIC SCOLIOSIS BEFORE AND AFTER SURGICAL CORRECTION

T. Langlais^1,2, X. du Cluzel³, N. Mainard⁴, S. George³, L. Gajny¹, J. Dubousset¹, R. Vialle⁴, W. Skalli¹, C. Vergari¹

¹ENSAM, IBHGC-Institut de Biomécanique Humaine Georges Charpak, Paris, France; ²Département Orthopédie Pédiatrique, Hôpital des enfants, Purpan, Toulouse, France; ³Département Orthopédie Pédiatrique, Hôpital Necker Enfants Malades, APHP, UPC, Paris, France; ⁴Department of Pediatric Orthopedic surgery, Armand Trousseau Hospital, APHP, Sorbonne University, Paris, France

LOWER EXTREMITY GAIT BIOMECHANICS AND THEIR ASSOCIATION WITH TRUNK FLEXION IN PATIENTS WITH LUMBAR SPINAL STENOSIS

C. Nüesch^1,2, D. Koch^1,2, S. Schären¹, A. Mündermann^1,2, C. Netzer^1,2

¹University Hospital Basel, Basel, Switzerland; ²University Basel, Basel, Switzerland

RECOVERY OF SHOULDER MOTION DURING GAIT AT 1-WEEK, 3-MONTHS AND 1-YEAR AFTER SPINAL FUSION SURGERY IN AIS

T. Ackermans¹, S. Schelfaut², P. Severijns¹, P. Moens², L. Moke^1,2, L. Scheys^1,2

¹KU Leuven, Belgium; ²University Hospitals Leuven, Belgium

TO ASSESS THE RISK FOR A SURGICAL INTERVENTION: THROUGH FLOW BIOPHYSICAL MODELING OR MACHINE LEARNING?

I. Vignon-Clementel

INRIA, France

CFD VIRTUAL ANGIOGRAM FOR AVM PRE-INTERVENTIONAL TREATMENT PLANNING

A. Blanch-Granada¹, C. Sim Lim², J. Tsui², V. Muthurangu¹, V. Diaz-Zuccarini¹, S. Balabani¹

¹University College London, United Kingdom; ²Royal Free London NHS Foundation Trust, United Kingdom

ULTRASOUND-BASED FSI MODELING OF ABDOMINAL AORTIC ANEURYSMS INCLUDING PATIENT-SPECIFIC VELOCITY PROFILES

J. Fonken^1,2, E. van Engelen¹, M. Gillissen¹, K. Franse¹, M. van Sambeek^1,2, F. van de Vosse¹, R. Lopata¹

¹Eindhoven University of Technology, The Netherlands; ²Catharina Hospital Eindhoven, the Netherlands

USING DIGITAL TWIN TECHNOLOGY TO REDUCE ANIMAL STUDIES FOR DEVELOPMENT OF PERINATAL LIFE SUPPORT SYSTEMS

B. G. van Willigen^1,2, M. B. van der Hout-van der Jagt^1,2,3, W. Huberts^1,4, F. N. van de Vosse¹

¹Cardiovascular Biomechanics, Biomedical Engineering, Eindhoven University of Technology, The Netherlands; ²Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, The Netherlands; ³Signal Processing Systems, Electrical Engineering, Eindhoven University of Technology, The Netherlands; ⁴Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands

ASSESSMENT OF THE COMBINED EFFECTS OF VALVE PHENOTYPE AND ANEURYSM PROGRESSION ON ATAA HEMODYNAMICS

F. Galbiati^1,2, E. Vignali³, K. Capellini³, C. Morin², S. Avril², E. Costa¹, S. Celi³

¹RINA Consulting S.p.A., Italy; ²Mines Saint Etienne, INSERM, SAINBIOSE U1059, F-42023, Saint-Étienne, France; ³BioCardioLab, Fondazione Toscana Gabriele Monasterio, Massa, Italy

WHAT MECHANICAL QUANTITY DO CELLS REGULATE IN SOFT TISSUES?

C. J. Cyron^1,2

¹Hamburg University of Technology, Germany; ²Helmholtz-Zentrum Hereon, Germany

MODELING AND SIMULATION OF TISSUE GROWTH CAUSED BY CELL PROLIFERATION DURING MORPHOGENESIS

Y. Yokoyama¹, Y. Kameo^1,2, T. Adachi^1,2

¹Department of Micro Engineering, Graduate School of Engineering, Kyoto University, Japan; ²Institute for Life and Medical Sciences, Kyoto University, Japan

A HOMOGENIZED CONSTRAINED MIXTURE MODEL FOR HEART VALVE GROWTH AND REMODELING

E. Middendorp^1,2, F. Bräu^3,4, F. P. Baaijens^1,2, J. D. Humphrey⁵, C. J. Cyron^6,7, S. Loerakker^1,2

¹Department of Biomedical Engineering, Eindhoven University of Technology, the Netherlands; ²Institute of Complex Molecular Systems, Eindhoven University of Technology, the Netherlands; ³Singapore Eye Research Institute, Singapore National Eye Center, Singapore; ⁴Singapore-MIT Alliance for Research and Technology, Singapore; ⁵Department of Biomedical Engineering, Yale University, USA; ⁶Institute for Continuum and Material Mechanics, Hamburg University of Technology, Germany; ⁷Institute for Material Systems Modeling, Helmholtz-Zentrum, Germany

PARAMETER SENSITIVITY AND OPTIMIZATION OF THE MECHANO-IMMUNO-DRIVEN MODEL OF ENDOGENOUS TISSUE RESTORATION

H. Shirazi¹, T. Vervenne¹, L. Maes¹, A. Hendrickx², B. Meuris², N. Famaey¹

¹Department of Mechanical Engineering, KU Leuven, Belgium; ²Experimental Cardiac Surgery, KU Leuven, Belgium

RECONCILING THE MESO- AND MICRO-SCALE MECHANICAL PROPERTIES OF LUNG TISSUE USING COMPUTATIONAL MODELING

E. Dimbath¹, L. de Castro Brás², S. George², A. Vadati²

¹Duke University, USA; ²East Carolina University, USA

NEWS FROM THE DEEP: MULTISCALE TISSUE MECHANICS OF COLD-WATER CORALS IN A CHANGING OCEAN

U. Wolfram

Heriot-Watt University, United Kingdom

PRIMARY STABILITY OF CEMENTLESS TIBIAL TRAYS DURING STAIR DESCENT AND DEEP KNEE BEND: A MICRO-CT AND DVC ANALYSIS

L. S Wearne¹, S. Rapagna¹, M. Awadalla¹, G. Keene², M. Taylor¹, E. Perilli¹

¹Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia; ²Orthopaedic Department, SportsMed, Adelaide, South Australia, Australia

LONGITUDINAL SUBCHONDRAL BONE MICROSTRUCTURE AND JOINT LOADING IN RATS WITH POST-TRAUMATIC KNEE OSTEOARTHRITIS

J. Piet¹, L. Juret¹, M. Van Nuffel¹, G. Vande Velde¹, R. Lories¹, E. Dall'Ara², I. Jonkers¹

¹KU Leuven, Belgium; ²University of Sheffield, UK

MICROSCALE COMPACT BONE PROPERTIES OF PATIENTS WHO UNDERWENT HIP ARTHROPLASTY: INFLUENCE OF AGE AND GENDER

T. Kochetkova^1,2, M. S. Hanke³, M. Indermaur², A. Groetsch¹, S. Remund⁴, B. Neuenschwander⁴, J. Michler¹, K. A. Siebenrock³, P. Zysset², J. Schwiedrzik¹

¹Empa, Swiss Federal Laboratories for Materials Science and Technology, Thun, Switzerland; ²ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland; ³Department of Orthopedic Surgery, Inselspital, University of Bern, Switzerland; ⁴ALPS Institute, Bern University of Applied Sciences, Burgdorf, Switzerland

IN VIVO MECHANICAL CHARACTERIZATION OF THE OSTEOPOROTIC DISTRACTION CALLUS

J. J. Toscano-Angulo^1,4, J. Mora-Macías^2,4, P. Blázquez-Carmona^1,4, J. Morgaz Rodríguez³, R. Navarrete-Calvo³, J. Domínguez Abascal^1,4, E. Reina-Romo^1,4

¹Escuela Técnica Superior de Ingeniería, University of Seville, Spain; ²Escuela Técnica Superior de Ingeniería, University of Huelva, Spain; ³Hospital Clínico Veterinario, University of Córdoba, Spain; ⁴Instituto de Biomedicina de Sevilla, Spain

AN IMAGE-BASED METHODOLOGY TO QUANTIFY ULTRASONIC CELL DEFORMATION

M. Ballard

University of Southampton, United Kingdom

QUANTITATIVE ASSESSMENT OF BONE MICROARCHITECTURE IN THE HUMAN KNEE USING PHOTON-COUNTING CT IS FEASIBLE

F. Azari¹, W. Coudyzer², C. E. Wyers^3,4,5, J. P. van den Bergh^3,4, G. H. van Lenthe¹

¹Ku Leuven, Belgium; ²University Hospital Leuven, Leuven, Belgium; ³VieCuri Medical Center, Venlo, the Netherlands; ⁴Maastricht University, Maastricht, the Netherlands; ⁵Maastricht University Medical Centre, Maastricht, the Netherlands

EFFECTS OF THE COLLAGEN COMPOSITION ON THE MECHANICAL MICROENVIRONMENT OF BREAST CANCER CELLS.

P. Blázquez Carmona^1,2, R. Ruíz-Mateos-Brea^1,2, J. A. Sanz-Herrera^1,2, J. Barrasa-Fano³, H. Van Oosterwyck³, E. Reina-Romo^1,2

¹Instituto de Biomedicina de Sevilla, Spain; ²ETSI, Universidad de Sevilla, Spain; ³KU Leuven, Belgium

STRESS FIBERS IN AORTIC SMOOTH MUSCLE CELLS ALTER TEHIR DIRECTION TO ELEVATED STRAIN DIRECTION UNDER HYPERTENSION

S. Sugita, R. Kawai, Y. Ujihara, M. Nakamura

Nagoya Institute of Technology, Japan

THE HARD REALITY OF SCATTERED DATA TO PREDICT HEART RHYTHM DISORDERS

C. M. Buck¹, M. A. de Winter¹, A. G. de Lepper², M. van 't Veer^1,2, W. Huberts^1,3, F. N. van de Vosse¹, L. R. Dekker^1,2

¹Department of Biomedical Engineering, Eindhoven University of Technology, the Netherlands; ²Department of Cardiology, Catharina Hospital Eindhoven, the Netherlands; ³Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, the Netherlands

Investigation of the impact of nanoscale geometry on the mechanical properties of hydroxyapatite platelets

L. Ravazzano¹, L. Alfonso², F. Libonati^1,2

¹Italian Institute of Technology, Italy; ²Department of Mechanical, Energy, Management and Transport Engineering – DIME, University of Genova, 16100 Genova, Italy

Validation of a multimodal 2D-3D registration algorithm using unimodal synthetic experiments

F. Correia Marques¹, E. Wehrle^1,2, R. Müller¹

¹ETH Zürich, Switzerland; ²AO Research Institute Davos, Davos Platz, Switzerland

EVALUATION OF VENTRICULAR STIFFNESS OF FROGS AND SNAKES

M. Ito¹, V. D. Nguyen², Y. Ogura¹, S. Sugita¹, M. Nakamura¹, Y. Ujihara¹

¹Nagoya Institute of Technology, Japan; ²The University of Utah, USA

SUBJECT-SPECIFIC FEMOROACETABULAR IMPINGEMENT SEVERITY COMPUTATIONAL ASSESSMENT OVER VARIOUS ACTIVITIES

T. E. Rayment, A. Jones, S. Williams

University of Leeds, United Kingdom

PARAMETER FITTING FOR A VISCOELASTIC CONSTITUTIVE MODEL USING A MACHINE LEARNING MODEL

M. O. Barra Pavez

Universidad de Santiago de Chile, Chile

Development of a Female Finite Element Model of the Cervical Spine

A. Silva¹, G. Carmo^1,2, R. Alves de Sousa^1,2, F. Fernandes^1,2, M. Parente³

¹TEMA - Centre for Mechanical Technology and Automation, Department of Mechanical Engineering, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal; ²LASI - Intelligent Systems Associate Laboratory, Portugal; ³Department of Mechanical Engineering, Faculty of Engineering, University of Porto, 4000-465 Porto, Portugal

The effect of substrate stiffness on astrocytes and leptomeningeal cells

A. J. Greaney, M. Abubaker, C. McCarthy, J. Mulvihill

University of Limerick, Ireland

Pre-training varied vascular geometries with a deep learning side network in physics-informed neural network simulations of vascular fluid dynamics

H. S. Wong, B. Li, W. X. Chan, C. H. Yap

Imperial College London, United Kingdom

ELUCIDATING THE MECHANICAL SIGNATURE OF DIFFERENT BRAIN LESIONS USING DYNAMIC NANOINDENTATION

U. Gautam¹, P. Narwal², A. Suri², S. Roy¹

¹Department of Applied Mechanics, Indian Institute of Technology Delhi, India; ²Department of Neurosurgery, All India Institute Of Medical Science Delhi, India

Intra-operator comparison of two models to predict vertebral failure on the same experimental dataset

V. Allard^1,2, C. Heidsieck³, C. Confavreux^1,4, F. Bermond², C. Travert³, L. Gajny³, W. Skalli³, D. Mitton², H. Follet¹

¹Univ Lyon, Univ Claude Bernard Lyon 1, INSERM, LYOS UMRS 1033, France; ²Univ Lyon, Univ Gustave Eiffel, Univ Claude Bernard Lyon 1, LBMC UMR_T 9406, 69622 Lyon, France; ³Arts et Métiers Institute of Technologie, IBHGC, France; ⁴Service de rhumatologie Sud, Hospices Civils de Lyon, France

Predicting impact response of human femur using material mapping strategy

A. Malik, V. V. Yadav, A. Chawla, N. V. Datla

Indian Institute of Technology Delhi, India

CODE VERIFICATION OF THE MICRO FINITE ELEMENT SOLVER PAROSOL USING THE METHOD OF MANUFACTURED SOLUTIONS

F. Trommer^1,2, P. Bhattacharya^1,2

¹INSIGNEO institute for in silico medicine, University of Sheffield, United Kingdom; ²Department of Mechanical Engineering, University of Sheffield, United Kingdom

NUMERICAL DETERMINATION OF AN ANATOMICAL STRUCTURE’S UNLOADED STATE FROM IN VIVO MEDICAL IMAGING

N. Collin^1,2, B. Watrisse¹, S. Le Floc'h¹, D. Ambard², J. Sigüenza²

¹Laboratoire de Mécanique et Génie Civil (LMGC, Montpellier, France; ²Sim&Cure, Montpellier, France

VALIDATION OF A MULTIMODAL 2D-3D REGISTRATION ALGORITHM USING UNIMODAL SYNTHETIC EXPERIMENTS

F. Correia Marques¹, E. Wehrle^1,2, R. Müller¹

¹Institute for Biomechanics, ETH Zurich, Zurich, Switzerland; ²AO Research Institute Davos, Davos Platz, Switzerland

STRAIN RATIO DISTRIBUTIONS CAN ELEGANTLY DESCRIBE THE EFFECT OF LESION LOCATION AND SIZE IN FEMORAL METASTASES

A. Rizvi¹, C. Scott², S. Seth³, A. H. Simpson⁴, P. Pankaj¹

¹School of Engineering, The University of Edinburgh, UK; ²Department of Orthopaedics, Royal Infirmary of Edinburgh, UK; ³School of Informatics, The University of Edinburgh, UK; ⁴Edinburgh Medical School, The University of Edinburgh, UK

AN UNSUPERVISED METHOD TO DETECT THE LEFT ATRIAL APPENDAGES AND CLASSIFY THEIR MORPHOLOGIES

V. Martorana¹, G. M. Bosi², M. Lee², G. Burriesci², C. Coronnello³, M. Tumminello¹

¹University of Palermo, Italy; ²University College London, United Kingdom; ³Ri.MED Foundation, Italy

BONE REMODELLING WITH ARTIFICIAL NEURAL NETWORKS

A. Pais¹, J. Lino Alves^1,2, J. Belinha³

¹INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering, Portugal; ²FEUP - Faculty of Engineering, University of Porto; ³ISEP - School of Engineering, Polytechnic of Porto

OPTIMIZATION AND INDUSTRIALIZATION OF A METABOLIC HOLTER DEVICE AND SOFTWARE DEVELOPMENT

E. Bori¹, M. Mouton¹, C. De Asmundis², R. Cannataro³, B. Innocenti¹

¹BEAMS Department (Bio Electro and Mechanical Systems), École Polytechnique de Bruxelles, Université Libre de Bruxelles, Brussel, Belgium; ²Heart Rhythm Management Centre, Universitair Ziekenhuis Brussel–Vrije Universiteit Brussel, Brussel, Belgium; ³Galascreen Laboratories, University of Calabria, Rende, Italy

DEEP LEARNING APPROACH FOR IN-STENT RESTENOSIS USING BIOLOGICALLY-INFORMED NEURAL NETWORKS

J. Shi, K. Manjunatha, S. Reese

Institute of Applied Mechanics, RWTH Aachen University, Germany

PRE-TRAINING VARIED VASCULAR GEOMETRIES WITH A DEEP LEARNING SIDE NETWORK IN PHYSICS-INFORMED NEURAL NETWORK SIMULATIONS OF VASCULAR FLUID DYNAMICS

H. S. Wong, B. Li, W. X. Chan, C. H. Yap

Department of Bioengineering, Imperial College London, United Kingdom

2D-UNET BASED APPROACH FOR 3D SEGMENTATION OF CORONARY ARTERY FROM COMPUTED TOMOGRAPHY ANGIOGRAPHY

G. Nannini¹, S. Saitta¹, A. Baggiano², G. Pontone², A. Redaelli¹

¹Politecnico di Milano, Italy; ²Centro Cardiologico Monzino, Italy

CFD-BASED SYNTHETIC DATA GENERATION FOR MACHINE LEARNING BASED PRESSURE DROP ASSESSMENT IN AORTIC STENOSIS

T. I. Matei^1,2, A. B. Popescu^1,2, C. I. Nita¹, C. F. Ciusdel^1,2, L. M. Itu^1,2

¹Transilvania University of Brasov, Romania; ²Siemens SRL, Romania

SINE-BASED ACTIVATION FUNCTION IS SUPERIOR IN PHYSICS-INFORMED NEURAL NETWORK FOR CARDIOVASCULAR FLOWS

A. Aghaee, M. O. Khan

Department Electrical, Computer and Biomedical Engineering, Toronto Metropolitan University, Toronto, ON, Canada

THREE-DIMENSIONAL FLOW RECONSTRUCTION IN A DISSECTED AORTA FROM 4D-MRI DATA

D. Ahmed¹, C. Stokes^2,3, N. Lind⁴, F. Haupt⁴, D. Becker⁵, V. Muthurangu⁶, H. Von Tengg-Kobligk⁴, S. Balabani^2,3, V. Diaz-Zuccarini^2,3, G. Papadakis¹

¹Department of Aeronautics, Imperial College London, United Kingdom; ²Department of Mechanical Engineering, University College London, United Kingdom; ³Wellcome-EPSRC Centre for Interventional Surgical Sciences, London, United Kingdom; ⁴Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern, Switzerland.; ⁵Clinic of Vascular Surgery, Inselspital, University of Bern, Switzerland; ⁶Centre for Translational Cardiovascular Imaging, University College London, United Kingdom

THE HARD REALITY OF SCATTERED DATA TO PREDICT HEART RHYTHM DISORDERS

C. M. Buck¹, M. A. de Winter¹, A. G. de Lepper², M. van 't Veer^1,2, W. Huberts^2,3, F. N. van de Vosse¹, L. R. Dekker^1,2

¹Department of Biomedical Engineering, Eindhoven University of Technology, the Netherlands; ²Department of Cardiology, Catharina Hospital Eindhoven, the Netherlands; ³Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, the Netherlands

REVERSE HOMOGENIZATION USING NEURAL NETWORKS FOR STRESS SHIELDING MINIMIZATION

A. Pais¹, J. Lino Alves^1,2, J. Belinha³

¹INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering, Portugal; ²FEUP - Faculty of Engineering, University of Porto; ³ISEP - School of Engineering, Polytechnic of Porto

PARAMETER FITTING FOR A VISCOELASTIC CONSTITUTIVE MODEL USING A MACHINE LEARNING MODEL

M. Barra¹, C. Garcia-Herrera¹, D. Celentano², F. Sahli², E. Herrera³

¹Universidad de Santiago de Chile, Chile; ²Pontificia Universidad Católica de Chile, Chile; ³Universidad de Chile, Chile

OBESITY'S IMPACT ON JOINT KINETICS AND KINEMATICS DURING GAIT

A. A. Hulleck¹, T. Liu², R. Prasad¹, R. Katmah¹, K. Khalaf¹, M. El Rich¹

¹Khalifa University, United Arab Emirates; ²University of Calgary, Canada

MEASUREMENT OF JOINT ANGLES IN A CANINE MUSCULOSKELETAL MODEL: DIRECT KINEMATICS VERSUS INVERSE KINEMATICS

M. Aghapour¹, C. Peham², H. Kainz³, B. Bockstahler¹

¹Section of Physical Therapy, Small Animal Surgery, Department for Companion Animals and Horses, University of Veterinary Medicine, Vienna; ²Movement Science Group, Equine Surgery, Department for Companion Animals and Horses, University of Veterinary Medicine, Vienna; ³Centre for Sport Science and University Sports, Department of Biomechanics, Kinesiology and Computer Science in Sport, Neuromechanics Research Group, University of Vienna

THE EFFECT OF OFFLOADING INSOLES ON GAIT KINEMATICS AND THE IMPLICATIONS FOR PLANTAR PRESSURE MANAGEMENT.

J. Shuang¹, A. Haron¹, G. Massey², M. Mansoubi², H. Dawes², G. Cooper¹, A. Weightman¹

¹School of Engineering, University of Manchester, United Kingdom; ²NIHR Exeter Biomedical Research Centre, Medical School, University of Exeter, United Kingdom

BEYOND GAIT SPEED

R. A. W. Felius^1,2, N. Wouda^1,4, M. Geerars^1,3, S. Bruijn², J. H. van Dieën², M. Punt¹

¹Utrecht University of applied sciences, The Netherlands; ²Vrije Universiteit Amsterdam, The Netherlands; ³Rehabilitation Center de Parkgraaf, The Netherlands; ⁴De Hoogstraat Revalidation, The Netherlands

TIME VS. SPACE: COMPARING GAIT CYCLE NORMALIZATION METHODS AND THEIR EFFECT ON FOOT PLACEMENT CONTROL

S. Fleischmann¹, J. Shanbhag², J. Miehling², S. Wartzack², S. Leyendecker³, A. D. Koelewijn¹, B. M. Eskofier¹

¹Machine Learning and Data Analytics Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany; ²Engineering Design, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany; ³Institute of Applied Dynamics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany

WEARABLE SENSOR AND MACHINE LEARNING ESTIMATION OF KNEE MOMENTS FOR HEALTHY PARTICIPANTS

A. Fishman¹, A. Sabaty², K. Y. Levi², A. G. Fischer¹

¹Department of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel; ²Department of Electrical & Computer Engineering, Technion - Israel Institute of Technology, Haifa, Israel

APONEUROSIS INSPIRED VARIABLE STIFFNESS FOR SOFT ROBOTICS

H. McAleese, A. Weightman, G. Cooper

University of Manchester, United Kingdom

NEW INSIGHTS FOR THE DESIGN OF BIONIC ROBOTS

D. Xu, X. Jiang, W. Quan, H. Zhou, F. Gusztáv, Y. Gu

Ningbo University, China, People's Republic of

BIONIC MUSCLE-INSPIRED DESIGN OF CABLE-DRIVEN LOWER LIMB REHABILITATION EXOSKELETON (C-LREX)

R. Prasad¹, K. Khalaf¹, M. I. Awad¹, S. K. Agrawal², M. El-Rich¹

¹Khalifa University, United Arab Emirates; ²Columbia University, United States of America

KINEMATICS OF UPPER LIMB MOVEMENT IN RHINO:GRASSHOPPER

K. Senvaitis, K. Daunoravičienė

Vilniaus Gediminas Technical University, Lithuania

PARTICLE TRACING IN AORTIC ROOT MODELS INVESTIGATING SINUS WASHOUT IN TRANSCATHETER VALVE THROMBOSIS PATIENTS

K.-M. Bornemann¹, S. E. Jahren¹, P. Corso¹, C. Demirel², S. Stortecky², D. Obrist¹

¹ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland; ²Department of Cardiology, Inselspital, University of Bern, Switzerland

POTENTIAL OF USING SHELL ELEMENTS METHODS IN FSI SIMULATIONS OF PULMONARY ARTERIES

H. Moradi¹, F. van de Vosse¹, W. Huberts^1,2

¹Eindhoven University of Technology, the Netherlands;; ²Maastricht University, the Netherlands

IN-VITRO AND IN-SILICO MODELING OF THE EFFECT OF GAG ON THE OPENING ANGLE OF THE ASCENDING PORCINE AORTA

N. Ghadie¹, J.-P. St-Pierre², M. Labrosse^1,3

¹Mechanical Engineering Department, University of Ottawa, Canada; ²Chemical and Biological Engineering Department, University of Ottawa, Canada; ³Department of Cardiac Surgery, University of Ottawa Heart Institute, Canada

A SELF-POWERED VENOUS BLOOD PUMP FOR SINGLE-VENTRICLE HEART DISEASE

R. Rasooli¹, K. E. T. Giljarhus¹, I. W. Jolma¹, J. L. Vinningland², H. Holmstrom³, A. Hiorth¹

¹University of Stavanger, Norway; ²Norwegian Research Center (NORCE), Norway; ³University of Oslo, Norway

MODELLING TRANSCATHETER MITRAL VALVE REPLACEMENT USING THE LIVING HEART PROJECT

c. catalano, s. pasta

University of Palermo, Italy

EVALUATION OF 4D ULTRASOUND DATA TO DETERMINE THE RELATIONSHIP BETWEEN 3D AORTIC WALL DISPLACEMENT AND AGE

K. E. Kerr¹, W. Derwich², A. Wittek¹, C. Blase^1,3

¹Personalized Biomedical Engineering Lab, Frankfurt University of Applied Sciences, Germany; ²Vascular and Endovascular Surgery, University Hospital Frankfurt, Germany; ³Biosciences, Goethe University Frankfurt, Germany

CAN THE GEOMETRY OF THE ATHEROMA PLAQUE INFLUENCE ON DRUG TRANSMURAL TRANSPORT ON DRUG ELUTING STENTS?

E. Peña^1,2, J. Escuer¹, E. Pina¹, M. A Martínez^1,2

¹Aragón Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza; ²Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN)

COUPLED MODELING OF DRUG COATED BALOON TREATMENT OF PERIPHERAL ARTERY DISEASE

L. Spahić¹, L. Benolić¹, S. Ur Rehman Qamar¹, V. Simić^1,2, B. Milićević^1,3, M. Milošević^1,2,4, N. Filipović^1,3

¹Research and Development Center for Bioengineering BioIRC,Kragujevac, Serbia; ²Institute for Information Technologies, University of Kragujevac, Kragujevac, Serbia; ³Faculty of Engineering, University of Kragujevac, Serbia; ⁴Belgrade Metropolitan University, Belgrade, Serbia

STENT-GRAFTS DERIVED FROM AUXETIC UNIT CELLS: NUMERICAL SIMULATION OF DEPLOYMENT INTO A CURVED ARTERY

R. S. Vellaparambil^1,2, W.-S. Han¹, P. Di Giovanni², S. Avril¹

¹Centre CIS, Mines Saint-Etienne, Université Jean Monnet Saint-Etienne, INSERM, SAINBIOSE U1059, F-42023 Saint-Etienne, France; ²Research and Development Department, HSL S.R.L, Trento, Italy

FUNDAMENTAL INSIGHTS INTO STENT-VESSEL INTERACTIONS THROUGH A NOVEL CONSTITUTIVE LAW AND IN-SILICO FRAMEWORK

J. Concannon, P. McGarry

University of Galway, Ireland

COMPUTATIONAL MODELING OF IN-STENT RESTENOSIS: PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION

K. Manjunatha¹, M. Behr², F. Vogt³, S. Reese¹

¹Institute of Applied Mechanics, RWTH Aachen University, Germany; ²Chair for Computational Analysis of Technical Systems, RWTH Aachen University, Germany; ³Department of Cardiology, Pulmonology, Intensive Care and Vascular Medicine, RWTH Aachen University, Germany

EXAMINING THE EFFECT OF PARAMETERS ON MECHANOBIOLOGY ATHEROMA PLAQUE GROWTH MODEL

P. Hernández López, M. Á. Martínez Barca, E. Peña Baquedano, M. Cilla Hernández

University of Zaragoza, Spain

AN IMAGE-BASED METHODOLOGY TO QUANTIFY ULTRASONIC CELL DEFORMATION

M. Ballard, A. Marek, F. Pierron

University of Southampton, United Kingdom

ELECTROSPUN POLYCAPROLACTONE 3D FIBROUS SCAFFOLD FOR HUMAN PERIODONTAL LIGAMENT CELLS MECHANOBIOLOGY

R. Gauthier¹, N. Attik^2,3, V. Salles^2,6,7, B. Grosgogeat^2,3,4, K. Gritsch^2,3,4, A.-M. Trunfio-Sfarghiu⁵

¹Univ Lyon,CNRS, INSA Lyon, UCBL, MATEIS, UMR5510, France; ²Univ Lyon - Claude Bernard Lyon 1, UMR CNRS 5615, Laboratoire des Multimatériaux et Interfaces, France; ³Univ Lyon, Université Claude Bernard Lyon 1, Faculté d’Odontologie, France; ⁴Hospices Civils de Lyon, Service d’Odontologie, 69007 Lyon, France; ⁵Univ Lyon, INSA-Lyon, CNRS UMR 5259, LaMCoS, F-69621 Villeurbanne, France; ⁶LIMMS, CNRS-IIS UMI 2820, The University of Tokyo, Tokyo 153-8505, Japan; ⁷Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan

THE EFFECT OF SUBSTRATE STIFFNESS ON ASTROCYTES AND LEPTOMENINGEAL CELLS

A. J. Greaney, M. Abubaker, C. McCarthy, J. Mulvihill

University of Limerick, Ireland

MECHANICAL RESPONSE OF ENDOTHELIAL CELLS TO SHEAR FLOW AS POSSIBLE MARKER IN DEVELOPMENT OF ATHEROSCLEROSIS

L. Orlová¹, I. Zumberg², O. Lisický¹, J. Jagoš¹, V. Čmiel², J. Burša¹

¹Brno University of Technology, Department of Biomechanics, Czech Republic; ²Brno University of Technology, Department of Biomedical Engineering, Czech Republic

A TOOL FOR STUDYING THE ROLE OF INTERCELLULAR STRESSES AND DYNAMIC CELL SHAPE MODULATIONS IN MECHANICAL INHIBITION OF CELL DIVISION

A. Saleem, Y. Lavi, B. Abu Kaff, L. Atia

Ben-Gurion university, Israel

EFFECTS OF THE COLLAGEN COMPOSITION ON THE MECHANICAL MICROENVIRONMENT OF BREAST CANCER CELLS.

P. Blázquez Carmona^1,2, R. Ruíz-Mateos-Brea^1,2, J. A. Sanz-Herrera^1,2, J. Barrasa-Fano³, H. Van Oosterwyck³, E. Reina-Romo^1,2

¹Instituto de Biomedicina de Sevilla, Spain; ²ETSI, Universidad de Sevilla, Spain; ³KU Leuven, Belgium

ACTIN FILAMENTS IN RESPONSE TO CHEMICAL OSTEOGENESIS SUPPLEMENTS ALTER THE MULITCELLULAR BEHAVIOR OF OSTEOCYTIC SPHEROIDS

J. Kim¹, T. Adachi², T. Matsumoto¹

¹Nagoya University, Japan; ²Kyoto University, Japan

SPATIAL MODELING OF YAP PHOSPHORYLATION THROUGH DIRECT INTERACTION WITH INTEGRIN ADHESIONS

H. Jafarinia¹, L. Shi², H. Wolfenson², A. Carlier¹

¹MERLN institute, Maastricht University, The Netherlands; ²The Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Israel

STRESS FIBERS IN AORTIC SMOOTH MUSCLE CELLS ALTER TEHIR DIRECTION TO ELEVATED STRAIN DIRECTION UNDER HYPERTENSION

S. Sugita, R. Kawai, Y. Ujihara, M. Nakamura

Nagoya Institute of Technology, Japan

WHAT COLLAGEN HYDROGEL FOR OPTIMAL MECHANOBIOLOGY OF 3D ENCAPSULLATED SMOOTH MUSCLE CELLS?

C. Techens¹, A. Ben Hassine¹, E.-J. Courtial², D. Eglin¹, S. Avril¹

¹Mines Saint-Etienne, Univ. Jean Monnet Saint-Etienne, INSERM, U 1059 SAINBIOSE, F-42023, France; ²3D.FAB, Univ. Lyon1, CNRS, INSA, CPE-Lyon, ICBMS, UMR 5246, France

INVESTIGATION OF THE IMPACT OF NANOSCALE GEOMETRY ON THE MECHANICAL PROPERTIES OF HYDROXYAPATITE PLATELETS

L. Ravazzano¹, L. Alfonso², F. Libonati^1,2

¹Center for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, 20133 Milano, Italy; ²Department of Mechanical, Energy, Management and Transport Engineering – DIME, University of Genova, 16100 Genova, Italy

FRACTURE MECHANICS OF CORTICAL BONE AT THE MICROSCALE BY SRΜCT IMAGING AND DIGITAL VOLUME CORRELATION

M. Peña Fernández¹, J. Schwiedrzik², A. Bürki³, F. Peyrin⁴, J. Michler², P. Zysset³, U. Wolfram¹

¹School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, United Kingdom; ²EMPA, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Mechanics of Materials and Nanostructures, Thun, Switzerland; ³ARTORG Centre for Biomedical Engineering Research, University of Bern, Bern, Switzerland; ⁴Université de Lyon, INSA Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS UMR 5220, Inserm U1294, CREATIS, Lyon, France

MICROCRACK NUCLEATION AND FRACTURE IN BONE ULTRASTRUCTURE: A COMPUTATIONAL STUDY

H. Alijani, T. Vaughan

Biomedical Engineering and Biomechanics Research Centre, School of Engineering, College of Science and Engineering, University of Galway, Galway, Ireland.

CICLOPE: AN OPEN SOURCE PACKAGE TO BUILD FINITE ELEMENT MODELS FROM MICRO COMPUTED TOMOGRAPHY IMAGES

G. Iori¹, M. Pani², G. Crimi³, G. Fraterrigo³, F. Taddei³, E. Schileo³

¹Synchrotron-light for Experimental Science and Applications in the Middle East, Jordan; ²School of Mechanical and Design Engineering, University of Portsmouth, UK; ³IRCCS Istituto Ortopedico Rizzoli, Italy

DOES 3D-REGISTRATION IMPROVE REPEATABILITY OF HR-PQCT-BASED HOMOGENIZED FINITE ELEMENT ANALYSIS?

M. Indermaur¹, D. Schenk¹, K. Lippuner², P. Zysset¹

¹ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland; ²Department of Osteoporosis, Inselspital, University of Bern, Switzerland

QUANTITATIVE ASSESSMENT OF BONE MICROARCHITECTURE IN THE HUMAN KNEE USING PHOTON-COUNTING CT IS FEASIBLE

F. Azari¹, W. Coudyzer², C. E. Wyers^3,4,5, J. P. van den Bergh^3,4, G. H. van Lenthe¹

¹Ku Leuven, Leuven, Belgium; ²University Hospital Leuven, Leuven, Belgium; ³VieCuri Medical Center, Venlo, the Netherlands; ⁴Maastricht University, Maastricht, the Netherlands; ⁵Maastricht University Medical Centre, Maastricht, the Netherlands

TOPOGRAPHY OPTIMISATION OF AN EXTERNAL CIRCULAR FIXATOR

W. Barros¹, F. Nemavhola², D. Desai¹, H. Ngwangwa³, T. Pandelani⁴

¹Tshwane University of Technology, South Africa; ²Durban University of Technology; ³University of South Africa; ⁴Defence and Security, Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa

INVESTIGATING SKELETAL PERI- AND POST-MORTEM TRAUMA

A. K Maier¹, A. Manzella¹, N. Marquez-Grant¹, P. Zioupos²

¹Cranfield University, UK; ²University of Hull, UK

PREDICTING IMPACT RESPONSE OF HUMAN FEMUR USING MATERIAL MAPPING STRATEGY

A. Malik, V. V. Yadav, A. Chawla, N. V. Datla

Department of Mechanical Engineering, Indian Institute of Technology Delhi, India

INFLUENCE OF BONE SCREW CONFIGURATIONS ON BONE HEALING BIOMECHANICS USING LOCKING COMPRESSION PLATE FIXATION

K. Khalaf¹, A. Azhang², M. Nikkhoo^2,3

¹Department of Biomedical Engineering, Khalifa University, Abu Dhabi, UAE; ²Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran; ³School of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan

BIOMECHANICAL COMPARISON OF TWO 2-MM HEADLESS CANNULATED SCREWS VERSUS A SINGLE 3-MM SCREW IN CAPITELLAR HUMERUS FRACTURE FIXATION

I. Zderic¹, D. Zhelev^1,2, S. Hristov², S. Ribagin³, S. Ivanov⁴, G. Richards¹, B. Gueorguiev¹

¹AO Research Institute Davos, Switzerland; ²University Multiprofile Hospital for Active Treatment Burgas, Bulgaria; ³University 'Prof. Dr. Asen Zlatarov', Bulgaria; ⁴University Hospital St. Marina, Bulgaria

INFLUENCE OF POLAR GRADATION ON DESIGN OF FUNCTIONALLY GRADED POROUS ACETABULAR COMPONENT

C. Mullakkara Saviour, S. Gupta

Indian Institute of Technology Kharagpur, India

EVOLUTION OF METABOLIC AND MECHANICAL COST OF WALKING WITH AN ABOVE KNEE PROSTHESIS SIMULATOR

A. Bonnet-Lebrun¹, X. Bonnet¹, A. Boos¹, L. Sedran¹, C. Heidsieck¹, M. Thomas-Pohl², H. Pillet¹

¹Institut de Biomecanique Humaine Georges Charpak, Arts et Metiers Sciences et Technologies, France; ²Service de Medecine et de Readaptation, Hôpital d’Instruction des Armees, France

CAN TRANSIENT SIMULATIONS IMPROVE LOWER LIMB-PROSTHESIS INTERACTION ANALYSIS?

V. Plesec, G. Harih

University of Maribor, Faculty of Mechanical Engineering, Slovenia

EVALUATION METHOD FOR HIGH FLEX LOOSENING OF POSTERIOR STABILIZED FEMORAL KNEE IMPLANTS UNDER DYNAMIC LOADING

J. Schwiesau^1,2, B. Fritz¹, T. M. Grupp^1,2

¹Aesculap AG, Germany; ²Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, LMU Munich, Germany

DESIGN OPTIMISATION OF NEXT-GENERATION SCAFFOLD-BASED BONE RECONSTRUCTION IMPLANTS: PHD THESIS PRESENTATION

B. M. Ferguson¹, J. Clark², Q. Li¹

¹School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Australia; ²Chris O’Brien Lifehouse, Australia

EFFECT OF FOOT ORTHOSES ON MULTI-SEGMENT FOOT KINEMATICS: A SYSTEMATIC REVIEW

Y. Meng¹, I. Bíró², Y. Gu³

¹Obuda University, Doctoral school on safety and security sciences; ²University of Szeged, Faculty of Engineering; ³Ningbo University, Faculty of Sports Science

DEVELOPMENT OF A 2-SEGMENT SPINAL FRACTURE FIXATION ROD TO MEASURE FORCES AND MOMENTS IN VIVO

M. Mangaleshwaran¹, J. Leong², S. Taylor¹

¹University College London, United Kingdom; ²Royal National Orthopaedic Hospital

A PROCEDURE FOR THE IN SILICO DESIGN OF ARTIFICIAL URINARY SPHINCTERS

J. V. Fotso Fogang¹, M. V. Mascolini², V. Salomoni³, C. Fontanella², E. L. Carniel², A. N. Natali²

¹Department of Civil Environmental and Architectural Engineering, University of Padova, Italy; ²Department of Industrial Engineering, University of Padova, Italy; ³Department of Management Engineering, University of Padova, Italy

REAL-TIME FATIGUE TRACKING USING ELECTROMYOGRAPHY DRIVEN MUSCULOSKELETAL MODELS

M I Mohamed Refai, M. Sartori

University of Twente, Netherlands, The

CLOSED-FORM MODELING OF THE SOLEUS MUSCULOTENDON UNIT

M. Nabipour, M. Sartori

University of Twente, Netherlands

UNDERSTANDING THE BIOMECHANICAL SIGNIFICANCE OF EXTRACELLULAR MATRIX FOR FUNCTIONAL MUSCLE FORCE USING A BIO-INSPIRED ARTIFICIAL MUSCLE

Z. Liu, A. Weightman, G. Cooper

The University of Manchester, United Kingdom

THE MOVEMENTS AND MORPHOLOGICAL CHARACTERISTICS OF THE SACROILIAC JOINT

S. J. Shin¹, A. Jeon¹, T. S. Bae², D.-S. Kwak¹

¹The Catholic University of Korea, South Korea; ²Jungwon University, South Korea

CAN WE FIND SAFE HINGE LEVEL DURING OPENING WEDGE HIGH TIBIAL OSTEOTOMY USING HETEROGENEOUS TIBIAL MODELS?

T. S. Bae¹, H. H. Baek¹, M. G. Kyung², S.-B. Kang², D.-S. Kwak³

¹Jungwon University, Korea, Republic of (South Korea); ²SMG-SNU Boramae Medical Center, Korea, Republic of (South Korea); ³The Catholic University of Korea, Korea, Republic of (South Korea)

DIRECT MEASUREMENT OF THE FORCES AND MOMENTS ACTING AT THE HINGE OF AN INSTRUMENTED HUMERAL COMPONENT FOR TOTAL ELBOW REPLACEMENT

M. Basiouny¹, S. Lambert², C. Kuenfoo³, S. Taylor¹

¹University College London, United Kingdom; ²University College London Hospital; ³Barking, Havering and Redbridge University Hospitals

MULTIMODAL MOLECULAR PROFILING TO PREDICT PATIENT OUTCOME AFTER CARTILAGE REPAIR SURGERY

M. J. HAARTMANS^2,3, K. S. EMANUEL^2,4, B. D. BALLUFF³, S. NAUTA³, G. J. TUIJHOF⁵, R. M. HEEREN³, P. J. EMANS², B. CILLERO-PASTOR^1,3

¹MERLN Institute for Technology-inspired Regenerative Medicine, Department of Cell Biology-Inspired Tissue Engineering (cBITE), Maastricht University, the Netherlands; ²Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery, Joint Preserving Clinic, CAPHRI Care and Public Health Research Institute, Maastricht University Medical Center+, the Netherlands; ³Maastricht MultiModal Molecular Imaging Institute (M4i), Division of Imaging Mass Spectrometry, Maastricht University, the Netherlands; ⁴Amsterdam UMC, Amsterdam Movement Sciences, Department of Orthopedic Surgery, the Netherlands; ⁵Faculty of Engineering Technology, Biomedical Device Design and Production Technology (BDDP), Twente University, the Netherlands

BIOMECHANICAL EVALUATION OF GENERATIVELY DESIGNED PATIENT-SPECIFIC HIGH TIBIAL OSTEOTOMY PLATE FIXATIONS

S. Kanagalingam¹, T. Boutefnouchet², P. Champneys³, M. Fernandez-Vicente⁴, D. Shepherd¹, D. Wimpenny⁴, L. Thomas-Seale¹

¹University Of Birmingham, United Kingdom; ²University Hospitals Birmingham NHS Trust, Birmingham, United Kingdom; ³Autodesk Technology Centre, Small Heath Business Park, Birmingham, United Kingdom; ⁴Manufacturing Technology Centre, Ansty Park, Coventry, United Kingdom

BIORESORBABLE LATTICE WEDGE FOR PATIENT SPECIFIC TIME DEPENDANT STIFFNESS IN HIGH TIBIAL OSTEOTOMY FIXATION

B. Hawthorn¹, S. Kanagalingam¹, A. Triantaphyllou², F. Khan², R. Dyson³, L. E. Thomas-Seale¹

¹University of Birmingham, United Kingdom; ²The Manufacturing Technology Centre (MTC) Ltd, United Kingdom; ³School of Mathematics, University of Birmingham, United Kingdom

EFFICIENT COMPUTATIONAL METHOD FOR ADJUSTING THE STIFFNESS OF INDIVIDUAL 3D-PRINTED INSOLES

F. Geiger¹, M. Kebbach¹, D. Vogel¹, V. Weissmann², L. Ruehrmund³, R. Bader¹

¹Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock,Germany; ²Institute for Polymer and Production Technologies e.V., 23966 Wismar, Germany; ³Department of Orthopaedics, Rostock University Medical Center, Rostock, Germany

SUBJECT-SPECIFIC FEMOROACETABULAR IMPINGEMENT SEVERITY COMPUTATIONAL ASSESSMENT OVER VARIOUS ACTIVITIES

T. E. Rayment, A. Jones, S. Williams

Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, United Kingdom

TOWARDS INDIVIDUALIZED BIOMECHANICAL MODELS IN MULTIPLE DOMAINS

I. Wechsler¹, A. D. Koelewijn², S. Wartzack¹, J. Miehling¹

¹Engineering Design, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; ²Machine Learning and Data Analytics Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

INTRA-OPERATOR COMPARISON OF TWO MODELS TO PREDICT VERTEBRAL FAILURE ON THE SAME EXPERIMENTAL DATASET

V. Allard^1,2, C. Heidsieck³, C. Confavreux^1,4, F. Bermond², C. Travert³, L. Gajny³, W. Skalli³, D. Mitton², H. Follet¹

¹Univ Lyon, Univ Claude Bernard Lyon 1, INSERM, LYOS UMRS 1033, France; ²Univ Lyon, Univ Gustave Eiffel, Univ Claude Bernard Lyon 1, LBMC UMR_T 9406, 69622 Lyon, France; ³Arts et Métiers ParisTech, IBHGC, France; ⁴Service de rhumatologie Sud, Hospices Civils de Lyon, France

IMPACT OF INTEROBSERVER LUMEN SEGMENTATION UNCERTAINTY IN FFR-CT: THE LOCATION OF THE STENOSIS MATTERS

D. Fernández-Martínez¹, J. M. Montanero¹, J. M. Nogales-Asensio², M. R. González-Fernández², C. Ferrera¹

¹Department of Mechanical, Energy and Materials Engineering, University of Extremadura, Spain; ²Hemodynamics and Interventional Cardiology Section, University Hospital of Badajoz, Spain

MODELING THIN LAYER HYPERELASTIC SOFT BIOLOGICAL TISSUES THROUGH MACRO-SPHERICAL COMPRESSION TESTS

L. K. TAPPERT^1,2, C. DE OLIVEIRA CAFIERO^1,2, A. BALDIT^1,2, A.-S. BONNET^1,2, P. LIPINSKI¹

¹LEM3-UMR-7239 CNRS - Univ. de Lorraine - Arts et Métiers ParisTech, France; ²ENIM, France

BIAXIAL STRETCH CAN HELP IN CORRECT INTERPRETATION OF COLLAGEN FIBRE ORIENTATION HISTOGRAMS

M. Turčanová¹, J. Fischer¹, M. Hermanová², Z. Bednařík², J. Burša¹

¹Brno University of Technology, Faculty of Mechanical Engineering, Czech Republic; ²1st Department of Pathology, St. Anne’s University Hospital Brno, Czech Republic

IMPORTANCE OF STRUCTURAL PARAMETERS IN CONSTITUTIVE MODELS OF AORTA

J. Fischer¹, M. Turčanová¹, V. Man¹, M. Hermanová², Z. Bednařík², J. Burša¹

¹Brno University of Technology, Faculty of Mechanical Engineering, Czech Republic; ²1st Department of Pathology, St. Anne’s University Hospital Brno, Czech Republic

DEVICE INDUCED DAMAGE OF ARTERIAL PORCINE TISSUE

M. Oude Vrielink¹, P. Timmermans¹, B. Van de Wetering², O. Van der Sluis^1,3

¹Philips Research, The Netherlands; ²LifeTec Group, The Netherlands; ³Eindhoven University of Technology, The Netherlands

ELUCIDATING THE MECHANICAL SIGNATURE OF DIFFERENT BRAIN LESIONS USING DYNAMIC NANOINDENTATION

U. Gautam¹, P. Narwal², A. Suri², S. Roy¹

¹Department of Applied Mechanics, Indian Institute of Technology Delhi, India; ²Department of Neurosurgery, All India Institute Of Medical Science Delhi, India

EVALUATION OF VENTRICULAR STIFFNESS OF FROGS AND SNAKES

M. Ito¹, V. D. Nguyen², Y. Ogura¹, S. Sugita¹, M. Nakamura¹, Y. Ujihara¹

¹Nagoya Institute of Technology, Japan; ²The University of Utah, USA

DEVELOPMENT OF A HUMAN WHOLE BODY MODEL TAKING INTO ACCOUNT THE CONNECTIVE TISSUE

H. Stark

Friedrich-Schiller-University Jena, Germany

BIOMECHANICAL IMPACT OF A SUBSEQUENT CHILDBIRTH ON THE FEMALE PELVIC FLOOR

D. Oliveira¹, M. Campos², R. Moura¹

¹INEGI, LAETA, & FEUP, Portugal; ²FEUP, Portugal

PREDICTING PELVIC FLOOR STRESSES DURING VAGINAL DELIVERY: A MACHINE LEARNING APPROACH

R. Moura¹, D. Oliveira¹, M. Parente², R. Natal Jorge²

¹Institute of Science and Innovation in Mechanical and Industrial Engineering, Portugal; ²Faculty of Engineering, University of Porto, Portugal

NUMERICAL EVALUATIONS OF FUNCTIONALLY GRADED POROUS INTERBODY CAGE FOR SPINAL FUSION

R. G. Talukdar, S. Dhara, S. Gupta

Indian Institute of Technology Kharagpur, India

ASSESSING THE EFFECT OF FIXATION LENGTH IN LUMBAR SPINE COMBINING RIGID AND FLEXIBLE BODY MODELING

S. Borrelli^1,2, G. Putame^1,2, A. L. Audenino^1,2, M. Terzini^1,2

¹PolitoBIOMed Lab, Politecnico di Torino, Turin, Italy; ²Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy

OPTIMIZATION OF TITANIUM SPINAL CAGES TO MAXIMIZE SYNTHETIC GRAFT CONTENT IN COMPOSITE IMPLANTS

S. Ghandour¹, P. Isaksson², C. Persson¹

¹Division of Biomedical Engineering, Uppsala University, Sweden; ²Division of Applied Mechanics, Uppsala University, Sweden

BIOMECHANICAL STABILITY OF LUMBAR SPINE INSTRUMENTED WITH INTERBODY FIXATION: WHICH CONSTRUCT PROVIDES BETTER STABILITY?

M. Einafshar¹, A. Kiapour², E. Massaad², J. Shin²

¹Department of Material and Production, Aalborg University, Aalborg, Denmark; ²Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

ANATOMY BASED TEST MODEL OF THE SACROILIAC JOINT FOR BIOMECHANICAL TESTING OF IMPLANTS

S. Krüger¹, T. Mendel^2,3, L. Becker⁴, S. Schedel⁵, M. Pumberger⁴, C. Schilling¹, B. W. Ullrich^2,3

¹Aesculap AG, Tuttlingen, Germany; ²Department of Trauma and Reconstructive Surgery, BG Klinikum Bergmannstrost Halle gGmbH, Halle, Germany; ³Department of Trauma Hand and Reconstructive Surgery, University Hospital Jena, Germany; ⁴Centrum für Muskuloskeletale Chirurgie, Charité – Universitätsmedizin Berlin, Germany; ⁵Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

VERTEBRAL BODY TETHERING VS SPINAL FUSION: LOOKING BEYOND THE RADIOGRAPHICAL OUTCOME

T. Ackermans¹, S. Schelfaut², P. Severijns¹, L. Moke^1,2, P. Moens², L. Scheys^1,2

¹KU Leuven, Belgium; ²University Hospitals Leuven, Belgium

FINITE ELEMENT STRAIN PREDICTION IN INTACT AND LESION-AFFECTED VERTEBRAL BODIES: A NEW VALIDATION EXPERIMENT

G. Fraterrigo^1,2, E. Schileo¹, F. Taddei¹, P. Erani¹, G. Rota¹, M. Berni¹, M. Baleani¹

¹IRCCS Istituto Ortopedico Rizzoli, Italy; ²Politecnico di Torino, Italy

INVESTIGATION OF THE BONE DENSITY IN AN ADOLESCENT IDIOPATHIC SCOLIOTIC VERTEBRA FOLLOWING A UNILATERAL MUSCLES PARALYSIS

M. Hosseinzadeh-Posti¹, M. Rajaeirad², A. Komeili³, Z. Kamal⁴

¹University of Guilan, Iran; ²University of Tehran, Iran; ³University of Calgary, Calgary, AB, Canada; ⁴University Medical Center Groningen, Netherlands, The

EFFECT OF NEGLECTING PASSIVE SPINAL STRUCTURES ON ESTIMATED JOINT LOADS: A MUSCULOSKELETAL MODELLING STUDY

L. Meszaros-Beller^1,2,3, M. Hammer^3,4, S. Schmitt^1,3,4, P. Pivonka^1,2

¹School of Mechanical, Medical and Process Engineering, Queensland University of Technology, Brisbane, Australia; ²Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, Australia; ³Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Germany; ⁴Stuttgart Center for Simulation Science (SC SimTech), University of Stuttgart, Germany

DEVELOPMENT OF A FEMALE FINITE ELEMENT MODEL OF THE CERVICAL SPINE

A. Silva¹, G. Carmo^1,2, R. Alves de Sousa^1,2, F. Fernandes^1,2, M. Parente³

¹TEMA - Centre for Mechanical Technology and Automation, Department of Mechanical Engineering, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal; ²LASI - Intelligent Systems Associate Laboratory, Portugal; ³Department of Mechanical Engineering, Faculty of Engineering, University of Porto, 4000-465 Porto, Portugal

INTRA AND INTER OPERATOR VARIABILITY IN A FINITE ELEMENT MODEL OF VERTEBRA FOR FAILURE LOAD PREDICTION

A. Levillain¹, V. Allard², E. Chevalier², C. Confavreux^2,3,4, J.-P. Roux², F. Bermond¹, D. Mitton¹, H. Follet²

¹Univ Lyon, Univ Gustave Eiffel, UCBL, LBMC UMR_T9406, Lyon, France; ²Univ Lyon, UCBL, INSERM, LYOS UMR 1033, Lyon, France; ³Hospices Civils de Lyon, Centre hospitalier Lyon Sud, Pierre Bénite, France; ⁴CEMOS, Service de Rhumatologie, Institut de Cancérologie, Lyon, France

MECHANICS UNDERLIES IMPAIRED ANGIOGENESIS AND ENDOTHELIAL MOSAICISM IN CEREBRAL CAVERNOUS MALFORMATIONS

A. Shapeti¹, J. Barrasa Fano¹, J. de Jong¹, A. Rahman Abdel Fattah¹, E. Planus², E. Faurobert², H. Van Oosterwyck^1,3

¹Biomechanics Section, KU Leuven, Belgium; ²Institute for Advanced Biosciences, France; ³Prometheus, Division of Skeletal Tissue Engineering, KU Leuven

OSTEOARTHRITIS PATIENTS CLASSIFICATION BASED ON SUPPORT VECTOR MACHINES AND REGULATORY NETWORK MODELS

M. Segarra-Queralt¹, M. Galofre¹, L. Tio², J. Monfort², J. C. Monllao², G. Piella¹, J. Noailly¹

¹BCN MedTech, Barcelona, Spain; ²IMIM, Barcelona, Spain

A MULTISCALE APPROACH TO STUDY CHONDROCYTE MECHANOBIOLOGY USING A CARTILAGE ON CHIP SETUP

S. Mukherjee¹, L. Spoelstra³, T. Le³, C. A. Paggi³, R. Lesage¹, J. B. Fano¹, H. Van Oosterwyck¹, M. Karperien³, L. Geris^1,2

¹KU Leuven, Belgium; ²University of Liege, Belgium; ³University of Twente, the Netherlands

A CORRELATIVE MULTIMODAL IMAGING APPROACH FOR SPATIAL TRANSCRIPTOMICS MECHANOREGULATION ANALYSIS

F. Correia Marques¹, A. Singh¹, N. Mathavan¹, D. Günther¹, E. Wehrle^1,2, R. Müller¹

¹Institute for Biomechanics, ETH Zurich, Zurich, Switzerland; ²AO Research Institute Davos, Davos Platz, Switzerland

EXPERIMENTAL INVESTIGATIONS AND CONSTITUTIVE MODELLING OF THE LAYER-DEPENDENT BEHAVIOUR OF THE HUMAN OESOPHAGUS

C. Durcan^1,2, M. Hossain¹, G. Chagnon², D. Perić¹, É. Girard^2,3

¹Zienkiewicz Centre for Computational Engineering, Faculty of Science and Engineering, Swansea University, Swansea, UK; ²Laboratoire TIMC, Université Grenoble Alpes, Grenoble, France; ³Laboratoire d’Anatomie des Alpes Françaises, Université Grenoble Alpes, Grenoble, France

MECHANICAL CHARACTERISATION OF FAT SUBSTITUTES FOR SUBCUTANEOUS DRUG DELIVERY EXPERIMENTAL MODEL

A. S. K. Kho^1,2, S. Béguin³, E. O'Cearbhaill^1,2, A. Ní Annaidh^1,2

¹UCD Centre for Biomedical Engineering, University College Dublin, Belfield Dublin 4, Ireland; ²I-Form Advanced Manufacturing Research Centre, School of Mechanical & Materials Engineering, University College Dublin, Belfield Dublin 4, Ireland; ³Becton Dickinson, Pottery Rd, Woodpark, Dún Laoghaire, Co. Dublin, Ireland

FREEZE DRIED WHARTON’S JELLY MECHANICAL RESPONSE CHANGE WITH HYDRATION

A. Baldit¹, M. Vassaux², L. Scomazzon³, C. Laurent¹, C. Mauprivez³, H. Kerdjoudj³

¹LEM3-UMR-7239, CNRS, University of Lorraine, France; ²IPR UMR 6251, CNRS, Université de Rennes, France; ³BIOS, Univ. de Reims Champagne Ardenne,EA 4691 Reims, France.

FROM ANIMAL MODEL TO HUMAN STUDY: A MECHANICAL AND STRUCTURAL ANALYSIS OF THE STOMACH

C. S. Holzer¹, A. Pukaluk¹, C. Viertler², P. Regitnig², A. W. Caulk³, M. Eschbach³, G. A. Holzapfel^1,4

¹Graz University of Technology, Austria; ²Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria; ³Surgical Innovations, Medtronic, North Haven, CT, USA; ⁴Department of Structural Engineering, NTNU, Trondheim, Norway

A CLOT COMPOSITION DEPENDANT HYPERELASTIC MODEL IN THE SIMULATION OF DIRECT ASPIRATION THROMBECTOMY

K. Bein Snee¹, R. McCarthy², P. McHugh¹, B. Fereidoonnezhad³, P. McGarry¹

¹University of Galway, Ireland; ²Cerenovus, Ireland; ³Biomechanical Engineering Department, TU Delft, the Netherlands

EVALUATION OF BIOMECHANICAL PROPERTIES OF SOFT TISSUES MIMICKING PHANTOMS BY IMPACT ANALYSES

A. Bouffandeau¹, A.-S. Poudrel¹, C. Brossier¹, G. Rosi², V.-H. Nguyen², G. Haïat¹

¹CNRS, MSME UMR CNRS 8208, France; ²Université Paris-Est Créteil, France

NOVEL APPROACHES IN COMPUTER-AIDED SCAFFOLD DESIGN FOR BONE REGENERATION

S. Checa

Charite-Universitaetsmedizin Berlin, Germany

RESTORING DISORGANISED TENDINOPATHIC TISSUE USING MAGNETIC TOPOGRAPHICAL CUES

A. K. Mansoor¹, A. Omidinia-Anarkoli², L. De Laporte², L. van IJzendoorn³, K. Ito¹, J. Foolen¹

¹Department of Biomedical Engineering, Technical University of Eindhoven, Netherlands; ²DWI Leibniz Institute for Interactive Materials, RWTH Aachen University, Germany; ³Department of Applied Physics, Eindhoven University of Technology, Netherlands

DESIGN, CHARACTERIZATION AND TESTING OF A PLATFORM FOR INVESTIGATING CELL RESPONSE TO CONTROLLED STRETCH

G. Putame¹, B. Masante^1,2, A. T. Lugas¹, M. Tosini¹, I. Roato², M. Terzini¹, F. Mussano², A. L. Audenino¹, D. Massai¹

¹PolitoBIOMed Lab and Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy; ²Bone and Dental Bioengineering Lab, CIR-Dental School, Department of Surgical Sciences, University of Torino, Italy

MECHANICAL CHARACTERIZATION OF A TRIPHASIC MEW PCL SCAFFOLD MIMICKING ARTICULAR CARTILAGE ARCHITECTURE

A. Amicone, M. X. T. Santschi, S. J. Ferguson

ETH Zürich, Institute for Biomechanics, Switzerland

LARGE-SCALE PRODUCTION OF ACPC-DERIVED CARTILAGE ORGANOIDS

F. Abinzano¹, J. C. A. Feenstra¹, R. P. A. Janssen^1,2,3, K. Ito¹

¹Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; ²Máxima Medical Center Eindhoven/Veldhoven, The Netherlands; ³Department of Paramedical Sciences, Fontys University of Applied Sciences, Eindhoven, The Netherlands

MODERN AI MEETS BIOMECHANICS: A NEW PARADIGM FOR IN SILICO MEDICINE

T.-T. Dao

Centrale Lille Institut, France

PREDICTION OF KNEE OSTEOARTHRITIS USING MACHINE LEARNING ENHANCED FINITE ELEMENT MODELING APPROACH – DATA FROM OSTEOARTHRITIS INITIATIVE

M. J. Turunen¹, T. A. T. Nurmirinta¹, M. K. Liukkonen², J. Tohka¹, M. E. Mononen¹

¹University of Eastern Finland, Finland; ²Kuopio university Hospital, Finland

PREDICTING THE PREMORBID ANATOMY OF THE SCAPULA USING GENERATIVE MODELS

O. B. Satir¹, P. Eghbali², A. Terrier^2,3, F. Becce³, P. Goetti³, A. Meylan³, K. Rothenbühler³, P. Büchler¹

¹ARTORG Center for Biomedical Engineering Research, Switzerland; ²Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland; ³Lausanne University Hospital (CHUV), Switzerland

AI-BASED GENERATION OF MULTIFARIOUS MEDICAL DATA FOR IN SILICO CLINICAL TRIALS

R. GANESAN¹, F. N. V. D. VOSSE¹, W. HUBERTS^1,2

¹Department of Biomedical Engineering, Eindhoven University Of Technology, The Netherlands; ²Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, The Netherlands

INFLUENCE OF ANISOTROPIC CORTICAL BONE PROPERTIES IN PERIPROSTHETIC HIP FRACTURES

Ö. Cebeci^1,2, D. Cronin³, M. Sämann⁴, S. Checa²

¹IAT Ingenieurgesellschaft für Automobiltechnik mbH; ²Julius Wolff Institute, Berlin Institute of Health (BIH); ³Department of Mechanical and Mechatronics Engineering, University of Waterloo; ⁴Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock

COATINGS OSTEOINDUCTIVE EFFECT CALIBRATION IN ASEPTIC LOOSENING SIMULATION OF ANIMAL OSTEOINTEGRATION EXPERIMENT

S. Baroni^1,2, S. Oliviero^1,2, A. A. La Mattina^1,2, M. Viceconti^1,2

¹Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Italy; ²Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

PATIENT-SPECIFIC FINITE ELEMENT MODEL FOR INTRAOPERATIVE FRACTURES PREDICTION WITH A COMMERCIAL DESIGN

M. Petrucci^1,2, A. A. La Mattina^1,2, C. Curreli^1,2, M. Viceconti^1,2

¹University of Bologna, Italy; ²Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

DISRUPTED LUBRICATION METHODOLOGY TO REPLICATE SQUEAKING ON CERAMIC ON CERAMIC HIP JOINT REPLACEMENTS

O. O'Dwyer Lancaster-Jones

DePuy Synthes

SAME OFFSET, DIFFERENT STABILITY: HOW HEAD LENGTH AFFECTS TAPER JUNCTION MICROMOTIONS IN TOTAL HIP ARTHROPLASTY

F. A. Bologna^1,2, G. Putame^1,2, A. L. Audenino^1,2, M. Terzini^1,2

¹Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy; ²PolitoBIOMed Lab, Politecnico di Torino, Turin, Italy

BIOMECHANICAL ANALYSIS OF HIP CEMENTLESS FEMORAL STEM DESIGNS IN PHYSIOLOGICAL AND OSTEOPOROTIC BONE DURING DIFFERENT STATIC LOADS

E. Bori¹, M. Formica², A. Zanirato², T. A. Revetria², J. Ditting¹, B. Innocenti¹

¹BEAMS Department, ULB - Université Libre de Bruxelles, Brussels, Belgium; ²Clinica Ortopedica, IRCCS Policlinico San Martino, Genoa, Italy

CHEMO-MECHANICAL MODELS OF ACTIVE CELL FORCES IN GROWTH AND REMODELLING

E. McEvoy

University of Galway, Ireland

MECHANICS OF CELL SPHEROIDS UNDER LARGE DEFORMATIONS

D. Giannopoulos¹, M. Schlittler², P. J. Thurner¹, A. Rossini², O. G. Andriotis¹

¹Institute of Lightweight Design and Structural Biomechanics, TU Wien, Vienna, Austria; ²Institute for Biomedicine (Affiliated to the University of Lübeck), Eurac Research, Bolzano, Italy

CROSSLINKING ENABLES LONG-RANGED CELL-MATRIX MECHANICS IN A HYBRID CELLULAR POTTS AND MOLECULAR DYNAMICS MODEL

E. Tsingos, B. H. Bakker, K. A E Keijzer, H. J. Hupkes, R. M H Merks

Leiden University, Netherlands

AGENT-BASED MODELING OF SPHEROID-ECM INTERACTION AND EVOLUTION UNDER FLUID FLOW

A. Carrasco-Mantis¹, E. Reina-Romo², J. A. Sanz-Herrera³

¹University of Seville, Spain; ²University of Seville, Spain; ³University of Seville, Spain

ALTERATION OF MICROTUBULE MECHANICS BY TAXOL: INSIGHTS FROM MULTISCALE ANALYSIS OF TUBULIN DYNAMICS

M. Cannariato, E. A. Zizzi, M. A. Deriu

PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy

TOWARDS PERSONALIZED SIMULATIONS AS PRE-PLANNING TOOL FOR CARDIOVASCULAR PROCEDURES

G. Luraghi

Politecnico di Milano, Italy

IN SILICO DEVELOPMENT OF PATIENT-SPECIFIC BARIATRIC SURGERY

I. Toniolo¹, A. Berardo^1,2, S. Perretta³, E. L. Carniel⁴

¹Department of Civil, Environmental and Architectural Engineering, University of Padova, Italy; ²Department of Biomedical Sciences, University of Padova, Italy; ³IRCAD France, Strasbourg, France; ⁴Department of Industrial Engineering, University of Padova, Italy

CAN EMG-DRIVEN MUSCULOSKELETAL MODELS ESTIMATE INDIVIDUAL MUSCLE DISPLACEMENTS?

C. P. Cop¹, K. L. Jakubowski^2,3, A. C. Schouten^1,4, B. Koopman¹, E. J. Perreault^5,6, M. Sartori¹

¹University of Twente, Netherlands, The; ²Emory University, USA; ³Georgia Institute of Technology, USA; ⁴Delft University of Technology, Netherlands, The; ⁵Northwestern University, USA; ⁶Shirley Ryan AbilityLab, USA

LIGAMENT PRE-TENSION DETERMINES OUTCOME IN SACROILIAC JOINT IN-SILICO MODELLING

M. Heyland¹, D. Maikath¹, P. Damm¹, K.-G. Hermann², K. Ziegeler²

¹Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany; ²Department of Radiology, Charité – Universitätsmedizin Berlin, Campus Mitte, Germany

AN ADVANCED MODELLING FRAMEWORK FOR ASSESSING KNEE ARTICULAR MECHANICS AND SOFT TISSUE LOADING AFTER TOTAL KNEE ARTHROPLASTY

N. Guo¹, C. Smith², A. Trepczynski³, P. Damm³, B. Taylor¹, H. Hosseini¹

¹Department of Health Sciences and Technology, Institute for Biomechanics, ETH Zurich, Switzerland; ²Department of Biomedical Engineering, Steadman Philippon Research Institute, USA; ³Julius Wolff Institute, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Germany

DEVELOPMENT OF A 2-SEGMENT FOOT MODEL FOR KINEMATIC MEASUREMENT OF MEDICAL GAIT ANALYSIS

L. Bauer, M. Hamberger, W. Böcker, H. Polzer, S. F. Baumbach

LMU University Hospital Munich, Germany

HEEL PAD COMPRESSION AND IMPACT DURING GAIT USING ULTRASONOGRAPHY AND IMU SENSORS: A PILOT STUDY

T. Gerbrands, L. Schluter

Fontys University of Apllied Sciences, The Netherlands

A NEW SYNERGY-BASED FOOT MODEL: DESCRIPTION OF ARCHES MOBILITY IN HEALTY AND FLAT FEET DURING GAIT

M. Conconi¹, N. Sancisi¹, C. Belvedere², A. Leardini²

¹Dept. of Industrial Engineering – DIN, University of Bologna, Italy; ²Movement Analysis Laboratory, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

AN EXPLORATORY APPROACH TO MUSCULAR FATIGUE ASSESSMENT DURING EXOSKELETON-ASSISTED GAIT

S. Pizzocaro^1,2, R. Baptista^2,3, F. Salvaggio^2,4, C. Cavallo^2,3, S. Galasso^2,3,5, M. Schmid¹, A. M. De Nunzio^2,3

¹Dep. of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy; ²Dep. of Research and Development, LUNEX International University, Differdange, Luxembourg; ³Luxembourg Health & Sport Sciences Research Institute ASBL, Differdange, Luxembourg; ⁴Dep. of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy; ⁵Dep. of Electrical and Information Engineering, University of Cassino and Southern Lazio, Cassino, Italy

IN WATER AND ON LAND FORWARD AND BACKWARD SPATIOTEMPORAL GAIT CHARACTERISTICS

C. Monoli^1,2, M. Galli², J. A. Tuhtan¹

¹Tallinn University of Technology, Department of Computer System, Tallinn 12616, Estonia; ²Politecnico di Milano, Department of Electronics, Information and Bioengineering, Milano 20133, Italy

KINETICS OF RAT LOCOMOTION NEGOTIATING ACTIVE PERTUBATIONS

E. Andrada¹, D. Arnold², M. S. Fischer¹

¹Friedrich-Schiller-University Jena, Germany; ²University Hospital of Jena, ENT department, Germany

OPTIMALITY OF TRABECULAR BONE AT THE CONTINUUM LEVEL

P. Zysset

University of Bern, Switzerland

MECHANICAL PROPERTIES OF INDIVIDUAL OSTEOPOROTIC AND CONTROL TRABECULAE IN COMPRESSION

K. Haslinger¹, M. Frank^1,2, D. H. Pahr^1,2, P. J. Thurner¹

¹Institute of Lightweight Design and Structural Biomechanics, TU Wien, AT; ²Division Biomechanics, Karl Landsteiner University of Health Sciences, AT

MECHANICAL LOADING OF EX VIVO BOVINE TRABECULAR BONE IN 3D-PRINTED BIOREACTORS

A. V. Correa¹, M. Zojaji², A. M. Parkhill², B. A Kunath², J. F. Vivanco¹, R. Rainbow², H.-L. Ploeg²

¹Facultad de Ingeniería y Ciencias, Universidad Adolfo Ibáñez, Chile; ²Department of Mechanical and Materials Engineering, Queen's University, Canada

MICROMECHANICAL CHARACTERISATION OF OSTEOARTHRITIC SUBCHONDRAL BONE BY MICROPILLAR COMPRESSION

S. McPhee¹, L. Koria², M. Mengoni², M. Peña Fernández¹, R. Beck³, J. D Shephard³, C. Brockett⁴, U. Wolfram¹

¹Institute of Mechanical, Process and Energy Engineering, Heriot-Watt University, UK; ²Institute of Medical and Biological Engineering, University of Leeds, UK; ³Institute of Photonics and Quantum Sciences, Heriot-Watt University, UK; ⁴INSIGNEO Institute for in silico Medicine, University of Sheffield, UK

MYOCARDIAL TRABECULAE IN ZEBRAFISH EMBRYOS IMPROVE TISSUE DEFORMABILITY AND REDUCE STRESSES

A. G. Cairelli¹, A. Gendernalik², J. Vermot^1,3, J. Lee⁴, D. Bark Jr.², C. H. Yap¹

¹Department of Bioengineering, Imperial College London, London, United Kingdom; ²Department of Pediatrics, Washington University in St. Louis, St. Louis, United States of America; ³Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France; ⁴Department of Bioengineering, University of Texas at Arlington, Arlington, United States of America

A BIOPHYSICALLY DETAILED COMPUTATIONAL MODEL OF THE FOUR CHAMBER HUMAN HEART ELECTROMECHANICS

M. Fedele¹, R. Piersanti¹, F. Regazzoni¹, M. Salvador¹, P. C. Africa¹, M. Bucelli¹, A. Zingaro¹, L. Dede'¹, A. Quarteroni^1,2

¹Politecnico di Milano, Italy; ²École Polytechnique Fédérale de Lausanne, Switzerland

REGULATORY MECHANISMS IN CARDIAC ACTIVE MECHANICS: FROM MICROSCALE MODELS TO MULTISCALE NUMERICAL SIMULATIONS

F. Regazzoni¹, A. Quarteroni^1,2

¹MOX - Dipartimento di Matematica, Politecnico di Milano, Italy; ²Mathematics Institute, École Polytechnique Fédérale de Lausanne, Switzerland (Professor Emeritus)

STRAIN-CONTROLLED ENZYMIC COLLAGEN DEGRADATION CAN EXPLAIN THE HEALTHY NATIVE MYOCARDIAL FIBER ORGANIZATION AN IN-SILICO APPROACH

H. Hoursan^1,2, K. Janssens¹, T. Ristori^1,2, C. Bouten^1,2, P. Bovendeerd¹, S. Loerakker^1,2

¹Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; ²Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.

A THERMODYNAMIC FRAMEWORK FOR SARCOMERE EVOLUTION IN CARDIOMYOCYTES SUBJECTED TO DYNAMIC LOADING

R. J. Coleman, P. McGarry

University of Galway, Ireland

OXYGEN DIFFUSION DYNAMICS WITHIN THE INTERVERTEBRAL DISC - A NANOSCALE AGENT-BASED MODEL

L. Baumgartner, A. Kaniewski, J. Noailly

Universitat Pompeu Fabra, Spain

A MODEL TO EXPLORE INTERVERTEBRAL DISC CELL ACTIVITY IN ADVERSE BIOCHEMICAL ENVIRONMENTS

S. Tseranidou¹, P. Bermudez-Lekerika², M. Segarra-Queralt¹, B. Gantenbein², C. Le Maitre³, J. Piñero⁴, J. Noailly¹

¹Universitat Pompeu Fabra, Spain; ²Department for BioMedical Research (DBMR), Faculty of Medicine, University of Bern, Switzerland; ³Department of Oncology and Metabolism, University of Sheffield, United Kingdom; ⁴IMIM, Spain

A COHORT OF PATIENT-SPECIFIC AND VIRTUAL FINITE ELEMENT MODELS OF INTERVERTEBRAL DISCS AND MODEL VALIDATION

E. M. Muñoz-Moya, M. Rasouligandomani, C. Ruiz, G. Piella, J. Noailly

Universitat Pompeu Fabra, Spain

AI-BASED IDENTIFICATION OF ADULT SPINAL DEFORMITIES BASED ON MUSCLE ACTIVATIONS

P. Severijns^1,2, J. D'Espallier³, L. Moke¹, D. Volkaerts³, L. Scheys¹

¹Institute for Orthopaedic Research and Training (IORT), Faculty of Medicine, KU Leuven, Leuven, Belgium; ²Faculty of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; ³UCLL University of applied sciences, Research & Expertise, Digital solutions, Leuven, Belgium

BIOMECHANICAL EFFECTS OF LUMBAR MULTIFIDUS AND PSOAS MAJOR MUSCLE DYSFUNCTION ON THE LUMBOSACRAL SPINE

R. Remus¹, A. Lipphaus², S. Selkmann¹, B. Bender¹

¹Chair of Product Development, Dept. of Mechanical Engineering, Ruhr-University Bochum, Germany; ²Biomechanics Research Group, Dept. of Mechanical Engineering, Ruhr-University Bochum, Germany

GAIT PHASE IDENTIFICATION BASED ON IMU READOUTS USING THREE GRADIENT-BOOSTED MODELS

A. Khandan, R. Fathian, M. Nazarahari, H. Rouhani

University of Alberta, Canada

CLASSIFYING PHYSICAL ACTIVITY LEVEL VIA KINEMATIC GAIT DATA

S. Galasso^1,2,3, R. Baptista^1,3, M. Molinara², S. Pizzocaro^1,4, R. S. Calabrò⁵, A. M. De Nunzio^1,3

¹Department of Research and Development, LUNEX International University, Differdange, Luxembourg; ²Department of Electrical and Information Engineering, University of Cassino and Southern Lazio, Cassino, Italy; ³Luxembourg Health & Sport Sciences Research Institute ASBL, Differdange, Luxembourg; ⁴Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy; ⁵Istituto di Ricerca e Cura a Carattere Scientifico Centro Neurolesi “Bonino Pulejo”, Messina, Italy

ASSISTING CLINICAL DECISION-MAKING BY PREDICTING TREATMENT RESPONSE FOR PAEDIATRIC MOVEMENT DISORDERS

R. M. Visscher^1,2, J. Murer¹, F. Fatemeh^1,3, E. Viehweger^2,4, W. R. Taylor^1,3, R. Brunner^2,4, N. B. Singh^1,3

¹ETH Zürich, Switzerland; ²University of Basel, Switzerland; ³Signapore-ETH Centre, Singapore; ⁴University Children's Hospital Basel, Switzerland

FALL RECOVERY LIMITATIONS FOR YOUNG ADULT AND ELDERLY MODELS THROUGH COUPLED DEEP REINFORCEMENT LEARNING SIMULATIONS

K. Nowakowski¹, K. El Kirat¹, T.-T. Dao²

¹Université de Technologie de Compiègne, Alliance Sorbonne Université, CNRS, UMR 7338 Biomécanique et Bio-ingénierie, Centre de Recherche Royallieu, CS 60 319 Compiègne, France; ²Univ. Lille, CNRS, Centrale Lille, UMR 9013 - LaMcube - Laboratoire de Mécanique, Multiphysique, Multiéchelle, F-59000 Lille, France

ONLY IN UNLOADED ACTIVITIES TKA DESIGN FEATURES DOMINATE IN THE AMOUNT OF ROLLING AND SLIDING

P. Moewis¹, R. Ehrig^1,2, H. Hommel³, A. Trepczynski¹, L. Krahl¹, G. N Duda¹

¹Julius Wolff Institute, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Germany; ²Zuse Institut Berlin, Germany; ³Krankenhaus Märkisch-Oderland GmBH, Wriezen, Germany

SIX DOF KNEE GAIT KINEMATICS OF KINEMATIC ALIGNED TKA

A.-K. Einfeldt¹, L. Tücking², P. Savov², M. Ettinger², H. Windhagen², E. Jakubowitz¹

¹Laboratory for Biomechanics and Biomaterials, Hannover Medical School, Germany; ²Department of Orthopaedic Surgery, Diakovere Annastift, Germany

FE STUDY ON THE EFFECT OF PATIENT-RELATED VARIATIONS ON THE PRIMARY FIXATION OF A CEMENTLESS PEEK TIBIAL COMPONENT

C. Post¹, T. Bitter¹, I. van Langen¹, A. Briscoe², N. Verdonschot^1,3, D. Janssen¹

¹Radboud University Medical Center, Orthopaedic Research Laboratory, Nijmegen, The Netherlands; ²Invibio Ltd., Thornton Cleveleys, Lancashire, United Kingdom; ³University of Twente, Laboratory for Biomechanical Engineering, Enschede, The Netherlands

STUDY OF THE LOCATIONS AND MORPHOLOGY OF ISOLATED KNEE FOCAL CARTILAGE DEFECTS USING A STATISTICAL SHAPE MODELING APPROACH

M. Mohammad Sadeghi¹, E. Aşık², P. Emans^1,2, N. Tümer³, G. Tuijthof⁴, A. Roth^1,2

¹Maastricht University, The Netherlands; ²Avalanche Medical BV, Maastricht, The Netherlands; ³Department of Biomaterials & Tissue Biomechanics, Delft University of Technology, The Netherlands; ⁴Department of Biomechanical Engineering, University of Twente, The Netherlands

INFLUENCE OF LOADING CONDITION ON THE ABILITY TO PREDICT HUMERAL STRESS SHIELDING

C. Mueri¹, A. Henderson¹, G. Maquer¹, J. Bischoff², H. Seyed Hosseini¹, P. Favre¹

¹Zimmer Biomet, Switzerland; ²Zimmer Biomet, US