Conference Agenda

WALL DISTENSIBILITY MODERATELY AFFECTS WALL SHEAR STRESS TOPOLOGICAL SKELETON AT THE CAROTID BIFURCATION

S. Zambon¹, M. Arminio¹, D. A. Steinman², C. Chiastra¹, U. Morbiducci¹, D. Gallo¹

¹Politecnico di Torino, Italy; ²University of Toronto, Canada

BLOOD FLOW MODELLING IN CORONARY ARTERIES: NEWTONIAN OR NON-NEWTONIAN?

G. De Nisco¹, M. Lodi Rizzini¹, R. Verardi², C. Chiastra¹, G. De Ferrari², F. D'Ascenzo², D. Gallo¹, U. Morbiducci¹

¹PoliToBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy; ²Hemodynamic Laboratory, Department of Medical Sciences, University of Turin, Italy

A SPATIALLY VARYING MULTI-COMPARTMENT MODEL OF THE REGULATION OF CEREBRAL BLOOD FLOW AND VOLUME

S. J. Payne

National Taiwan University, Taiwan

DIGITAL TWIN ANALYSIS OF AORTIC ROOT FLOW DISTURBANCES FOLLOWING TRANSCATHETER IMPLANTATION AND 4D MRI

A. Banfalvi, S. Ringgaard, M. Abkar, P. Johansen, M. Colombo

Aarhus University, Denmark

EFFECTS OF INTERVERTEBRAL DISC DEGENERATION ON THE SURFACE STRAIN DISTRIBUTION OF HUMAN VERTEBRAE

G. Cavazzoni, M. Pasini, L. Cristofolini, M. Palanca

Dept of Industrial Engineering, Alma Mater Studiorum – University of Bologna, Bologna, IT

STRUCTURE AND MECHANICS OF THE INTERVERTEBRAL DISC-ENDPLATE JUNCTION ANALYSED USING SYNCHROTRON CT AND DVC

A. L. Parmenter¹, C. Disney², F. Bosi¹, P. Lee¹

¹University College London, United Kingdom; ²Diamond Light Source, United Kingdom

EFFECT OF FACET JOINT DEGENERATION ON SPINAL UNIT BIOMECHANICS

J. Warren, M. Mengoni

University of Leeds, institute of Medical and Biological Engineering, United Kingdom

THE EFFECT OF PROGRESSIVE HERNIATION ON LUMBAR INTERVERTEBRAL DISC SIX DEGREE OF FREEDOM MECHANICS

M. P. Russo, J. J. Costi

Biomechanics and Implants Laboratory, Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, Australia

INSTABILITY ANALYSIS AFTER THORACIC SPINAL COMPRESSION AND FLEXION-COMPRESSION TRAUMA: AN IN VITRO STUDY

C. Liebsch, A.-K. Greiner-Perth, H.-J. Wilke

Ulm University, Germany

PHYSICS-INFORMED NEURAL NETWORKS FOR PREDICTING FATIGUE DURING INTERMITTENT ISOMETRIC TASKS

I. Loi, K. Moustakas

University of Patras, Patras, Greece

ESTIMATION OF KNEE JOINT CONTACT FORCE MAXIMA DURING GAIT USING A VIDEO CAMERA AND DEMOGRAPHIC DATA

J. J. Lavikainen¹, L. Stenroth¹, P. Vartiainen¹, T. Alkjær², M. Liukkonen³, R. Korhonen¹, M. Mononen¹

¹University of Eastern Finland, Finland; ²University of Copenhagen; ³Kuopio University Hospital

LEARNING FACIAL MOTION USING DEEP REINFORCEMENT LEARNING AND FINITE ELEMENT MODELING

D. P. Nguyen¹, M.-C. HO BA THO¹, T.-T. DAO²

¹Université de technologie de Compiègne, CNRS, Biomechanics and Bioengineering, Centre de recherche Royallieu, CS 60 319 - 60 203, Compiègne Cedex, France; ²Univ. Lille, CNRS, Centrale Lille, UMR 9013 - LaMcube - Laboratoire de Mécanique, Multiphysique, Multiéchelle, F-59000 Lille, France

CRITICAL SHOULDER ANGLE VARIABILITY ESTIMATED WITH A CAUSAL BAYESIAN NETWORK

P. Eghbali¹, O. B. Satir², F. Becce³, P. Goetti³, P. Büchler², D. Pioletti¹, A. Terrier^1,3

¹EPFL, Switzerland; ²ARTORG Center for Biomedical Engineering Research, Switzerland; ³Lausanne University Hospital (CHUV), Switzerland

GENERALIZATION OF MACHINE LEARNING MODEL PREDICTIONS OF KNEE JOINT FORCES TO POST STROKE GAIT

G. Giarmatzis¹, C. Kokkotis¹, E. Giannakou¹, K. Vadikolias², N. Aggelousis¹

¹Physical Education and Sport Science Department, Democritus University of Thrace, Greece; ²Department of Medicine, Democritus University of Thrace, Greece

THE ROLE OF STATISTICAL SHAPE MODELS IN THE DESIGN FRAMEWORK OF OSSEOINTEGRATED IMPLANTS FOR DISTAL FEMUR

V. Betti¹, A. Aldieri², G. Galteri¹, M. L. Ruspi¹, K. Morellato³, E. Gruppioni³, M. Palanca¹, L. Cristofolini¹

¹Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Bologna, Italy; ²PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino, Italy; ³Centro Protesi INAIL, Vigorso, Bologna, Italy

IMPLANT STABILITY AND LOAD TRANSFER OF OSSEOINTEGRATED TRANSFEMORAL PROSTHESIS

G. Galteri¹, M. Palanca¹, V. Betti¹, K. Morellato², E. Gruppioni², L. Cristofolini¹

¹Dept of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Bologna, IT; ²Centro Protesi INAIL, Vigorso di Budrio, Bologna, IT

REASONS FOR OSTEOPENIA IN ABOVE THE KNEE AMPUTEES: A BIOMECHANICAL EXPLANATION

J. L. Zavaleta Ruiz¹, M. J Major², P. Pankaj¹

¹Institute for Bioengineering, School of Engineering, The University of Edinburgh, UK; ²Dept. of Physical Medicine & Rehabilitation, Dept. of Biomedical Engineering, Northwestern University, and Jesse Brown VA Medical Center, Chicago IL USA

DEVELOPMENT OF A PIPELINE FOR 3D PRINTED CUSTOMIZED PLANTAR FOOT ORTHOSIS BASED ON FEM AND GAIT ANALYSIS

Z. Sawacha^1,2, M. Crosato¹, E. Bertoncello³, A. Guiotto¹

¹Dept of Information Engineering, University of Padova, Italy; ²Dept of Medicine, University of Padova, Italy; ³Orthomedica srl, Padova, Italy

VERIFICATION OF A PASSIVE ANKLE-FOOT ORTHOSIS DESIGN METHOD BY USING TRUSS MODELS

D. Scherb, P. Steck, S. Wartzack, J. Miehling

Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Engineering Design, Martensstraße 9, 91058 Erlangen, Germany

COMPUTATIONAL SIMULATIAON OF HAEMODYNAMICS IN PATIENT WITH VA-ECMO

J.-g. Im¹, Y. Zhu², X. Y. Xu², I.-S. Jeong³, B. Gu¹

¹Chonnam National University, Korea; ²Imperial College, London; ³Chonnam National University Hospital, Korea

MULTI-OBJECTIVE OPTIMIZATION OF HOLLOW FIBER MEMBRANES ARRANGEMENT USING MODIFIED ENHANCED JAYA ALGORITHM

S. H. Monsefi^1,2, B. Haddadi¹, M. Gfoehler², M. Harasek¹

¹Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Vienna, Austria; ²Institute of Engineering Design and Product Development, TU Wien, Vienna, Austria

IMPACT OF SICKLE CELL DISEASE FOR OXYGEN TRANSPORT IN INTRACRANIAL ANEURYSMS

M. S.Bazzi¹, H. Wiputra², D. K. Wood³, V. H. Barocas⁴

¹University of Minnesota, United States of America; ²University of Minnesota, United States of America; ³University of Minnesota, United States of America; ⁴University of Minnesota, United States of America

HOW DO SINUSOIDAL SCAFFOLDS AFFECT FLUID FLOW-INDUCED WALL SHEAR STRESS AND MASS TRANSPORT?

T. Baumgartner¹, M. Bösenhofer^2,3, O. Guillaume^4,5, A. Ovsianikov^4,5, M. Harasek^2,3, M. Gföhler¹

¹TU Wien, Institute of Engineering Design and Product Development, Vienna, Austria; ²TU WIen, Institute of Chemical Engineering, Environmental and Bioscience Engineering, Vienna, Austria; ³K1-MET GmbH, Area 4 - Simulation and Analyses, Linz, Austria; ⁴TU Wien, Institute of Materials Science and Technology, Vienna, Austria; ⁵Austrian Cluster for Tissue Regeneration (https://www.tissue-regeneration.at), Vienna, Austria

DEVELOPMENT OF NASAL SPRAY DELIVERY SYSTEM TARGETING AT THE POSTERIOR NOSE FOR MUCOSAL IMMUNIZATION

J. Xi¹, A. Seifelnasr¹, M. Talaat¹, X. Si²

¹University of Massachusetts, Lowell, MA, United States of America; ²California Baptist University, Riverside, CA, United States of America

CLINICAL VALIDATION OF STATIC OPTIMIZATION DURING POST STROKE GAIT

G. Giarmatzis¹, E. Giannakou¹, A. Gkrekidis¹, K. Vadikolias², N. Aggelousis¹

¹School of Physical Education and Sport Science, Democritus University of Thrace, Greece; ²Department of Medicine, Democritus University of Thrace, Greece

PREDICTING KNEE CARTILAGE DEGENERATION IN OBESE ADULTS USING PATIENT-SPECIFIC MODELS: DATA FROM THE CAROT TRIAL

G. A Orozco¹, L. Stenroth^2,3, A. Esrafilian², P. Tanska², M. E. Mononen², T. Alkjær³, R. K. Korhonen², H. Isaksson¹

¹Lund University, Sweden; ²University of Eastern Finland, Finland; ³University of Copenhagen, Denmark

PATIENT-SPECIFIC BONE PLATES: DESIGN STRATEGIES AND BIOMECHANICAL PERFORMANCE

V. Moosabeiki¹, N. de Winter^1,3, M. Cruz Saldivar¹, S. Leeflang¹, M. Witbreuk², V. Lagerburg³, M. J. Mirzaali¹, A. A. Zadpoor¹

¹Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering, Delft University of Technology (TU Delft), Mekelweg 2, 2628 CD, Delft, The Netherlands; ²Department of Orthopaedic Surgery, OLVG, Oosterpark 9, 1091 AC, Amsterdam, the Netherlands; ³Medical Physics, OLVG, Oosterpark 9, 1091 AC, Amsterdam, the Netherlands

AUTOMATED MUSCLE LOCALIZATION AND MODEL-BASED ESTIMATION OF ANKLE TORQUES POST-STROKE VIA A WEARABLE SENSORISED LEG GARMENT

D. Simonetti¹, M. Hendriks², J. Herijgers³, C. Cuerdo del Río¹, B. Koopman¹, N. Keijsers², M. Sartori¹

¹University of Twente, Netherlands; ²Sint Maartenskliniek, Netherlands; ³Twente Medical System Int. (TMSi), Netherlands

INFLUENCE OF METASTATIC LESIONS ON TWO MODELS ASSESSING VERTEBRAL FAILURE

V. Allard^1,2, C. Confavreux^1,3, F. Bermond², M. Stadelmann⁴, R. Alkalay⁵, P. Zysset⁴, D. Mitton², H. Follet¹

¹Univ Lyon, Univ Claude Bernard Lyon 1, INSERM, LYOS UMRS 1033, France; ²Univ Lyon, Univ Gustave Eiffel, Univ Claude Bernard Lyon 1, LBMC UMR_T 9406, 69622 Lyon, France; ³Service de rhumatologie Sud, Hospices Civils de Lyon, France; ⁴ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland; ⁵Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA

MECHANOREGULATION OF BONE FORMATION DURING NON-UNIONS IN PREMATURELY AGEING MICE

J. J. Kendall¹, V. Baumann¹, N. Mathavan¹, E. Wehrle^1,2, R. Müller¹

¹ETH Zurich, Zurich, Switzerland; ²AO Research Institute Davos, Davos Platz, Switzerland

MECHANOBIOCHEMICAL BASED ORTHOTROPIC BONE REMODELING AROUND UNCEMENTED ACETABULAR COMPONENT

C. Mullakkara Saviour, B. Mathai, S. Gupta

Indian Institute of Technology Kharagpur, India

MECHANO-BIOLOGY OF TISSUE REGENERATION WITHIN SCAFFOLDS IN LARGE BONE DEFECTS COMORBID WITH TYPE 2 DIABETES

M. Jaber, D. Dias, P. S. Poh, G. N. Duda, S. Checa

Center for Musculoskeletal Biomechanics and Regeneration (Julius Wolff Institute), Charité – Universitätsmedizin Berlin, Berlin, Germany, Germany

PREMATURELY AGED POLGA MICE EXHIBIT DEGENERATED OSTEOCYTE NETWORK AND MECHANOSENSATION

D. Yilmaz¹, T. Parajasingam¹, L. Gregorio¹, C. P. Gehre¹, F. Correia Marques¹, X.-H. Qin¹, E. Wehrle^1,2, G. A. Kuhn¹, R. Müller¹

¹ETH Zurich, Zurich, Switzerland; ²AO Research Institute Davos, Davos Platz, Switzerland

POST-TRAUMATIC FIBRIL REORIENTATION IN CARTILAGE: ADAPTIVE IN SILICO MODEL VALIDATED AGAINST IN VITRO OA MODEL

S. A. Elahi¹, R. Castro Viñuelas¹, P. Tanska², R. K. Korhonen², R. Lories¹, N. Famaey¹, I. Jonkers¹

¹KU Leuven, Belgium; ²University of Eastern Finland, Finland

IMPACT OF VELOCITY ON MUSCLE FORCE GENERATION DURING LONG ECCENTRIC CONTRACTIONS

T. Siebert¹, S. Weidner¹, C. Rode², A. Tomalka¹

¹University of Stuttgart, Germany; ²University of Rostock, Germany

PREDICTIVE CONTROL OF PLANTARFLEXOR MUSCLE-TENDON FORCE DURING SIMULATED HUMAN HOPPING

M. Nabipour¹, G. S. Sawicki², M. Sartori¹

¹University of Twente, Netherlands; ²Georgia Institute of Technology, United States of America

A UNIFYING APPROACH FOR THE STANDARDISATION OF KINEMATIC SIGNALS

A. Ortigas Vásquez^1,2, W. R. Taylor³, B. Postolka³, P. Schütz³, A. Maas^1,2, M. Woiczinski², T. M. Grupp^1,2, A. Sauer^1,2

¹Research and Development, Aesculap AG, Tuttlingen, Germany; ²Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Centre Munich (MUM), Campus Grosshadern, Ludwig Maximilians University Munich, Munich, Germany; ³Laboratory for Movement Biomechanics, ETH Zurich, Switzerland

APPLICATION OF DIFFERENT OPTIMISATION CRITERIA TO STANDARDISE KINEMATIC SIGNALS

A. Sauer^1,2, A. Ortigas Vásquez^1,2, B. Postolka³, P. Schütz³, A. Maas^1,2, M. Woiczinski², T. M. Grupp^1,2, W. R. Taylor³

¹Research and Development, Aesculap AG, Tuttlingen, Germany; ²Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Centre Munich (MUM), Campus Grosshadern, Ludwig Maximilians University Munich, Munich, Germany; ³Laboratory for Movement Biomechanics, ETH Zurich, Switzerland

A LSTM FRAMEWORK FOR ANKLE JOINT BIOMECHANICS PREDICTIONS FROM INERTIAL SENSORS DURING GAIT

L. Xiang^1,2, Y. Gu^1,2, V. Shim¹, A. Wang¹, J. Fernandez^1,2,3

¹Auckland Bioengineering Institute, The University of Auckland, New Zealand; ²Faculty of Sports Science, Ningbo University, China; ³Department of Engineering Science, The University of Auckland, New Zealand

THE EFFECT OF RESPIRATION ON THE IN-VIVO MECHANICAL EVALUATION OF LINEA ALBA BY SHEARWAVE ELASTOGRAPHY

C. Vergari, S. Persohn, P.-Y. Rohan

École Nationale Supérieure d’Arts et Métiers, IBHGC-Institut de Biomécanique Humaine Georges Charpak, Paris, France

ESTIMATING CEREBRAL MECHANICAL PROPERTIES NON-INVASIVELY THROUGH THE USE OF TISSUE PULSATIONS IN THE HUMAN BRAIN

S. J. Payne¹, I. Henderson², A. Jerusalem², V. D. Nguyen², J. Nicholls³, J. Ince³, J. Minhas³, A. Lecchini-Visintini^3,4, E. Chung^3,5

¹National Taiwan University, Taiwan; ²Department of Engineering Science, University of Oxford, UK; ³CHiASM Research Group, NIHR Leicester Biomedical Research Centre, University of Leicester, UK; ⁴School of Electronics and Computer Science, University of Southampton, UK; ⁵Faculty of Life Sciences and Medicine, King’s College London, SE1 1UL

REGION-DEPENDENT MATERIAL PARAMETERS FOR FULL-SCALE HUMAN BRAIN SIMULATIONS

E. Griffiths, J. Hinrichsen, N. Reiter, S. Budday

Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

MECHANICAL PROPERTIES OF THE HUMAN PIA-ARACHNOID COMPLEX

P. Vandemaele¹, H. Fehervary¹, L. Maes¹, B. Depreitere², J. Vander Sloten¹, N. Famaey¹

¹Biomechanics Section, KU Leuven, Belgium; ²Department of Neurosurgery, University Hospital Leuven, Belgium

BIOMECHANICS OF THE FETAL MEMBRANE UNDER DIFFERENT PHYSIOLOGICAL CONDITIONS

D. Fidalgo¹, M. Oyen², D. Oliveira¹, M. Parente¹, R. Natal¹, K. Myers³

¹INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial, Portugal; ²Washington University, United States; ³Columbia University in The City of New York, United States

BIOMECHANICAL INTEGRITY OF THE CERVIX IN PATIENTS AT LOW- AND HIGH-RISK OF PRETERM BIRTH

E. Louwagie¹, J. Hairston², M. Mourad², R. Wapner², K. Myers¹

¹Mechanical Engineering, Columbia University, United States of America; ²Obstetrics and Gyencology, Columbia University, United States of America

PROPOSAL OF A NEW WRIST MODEL FOR SURGICAL PLANNING : THE ADDED BENEFITS OF 3D ANALYSIS

R. Winter^1,2, T. Poujade², P. Chabrand³, M.-O. Gauci¹

¹Unité de Recherche Clinique Côte d'Azur, Université Côte d'Azur, France; ²Newclip Technics, France; ³Institut des Sciences du Mouvement Etienne-Jules Marey, CNRS, Aix-Marseille Université, France

OPTIMIZING BONE REGENERATION IN 3D SCAFFOLDS WITH COMPUTER-AIDED TECHNOLOGY

P. Martín-Compaired¹, G. Nasello², M. A. Perez Anson¹

¹University of Zaragoza, Spain; ²KU Leuven, Belgium

TOWARDS A COMPUTER-AIDED PLANNING PROCEDURE FOR EPIPHYSIODESIS SURGERY

A. Baeten¹, W.-Y. Liu², F. van Doeveren², K. Ito¹, M. van der Steen², B. van Rietbergen¹

¹Eindhoven University of Technology, The Netherlands; ²Máxima Medical Center, The Netherlands

QUANTIFYING HUMERAL HEAD MIGRATION IN SHOULDER OSTEOARTHRITIS USING BIPLANAR RADIOGRAPHY

N. Daneshvarhashjin¹, F. Verhaegen¹, B. Innocenti², M. Skipper Andersen³, L. Scheys¹

¹Institute for Orthopaedic Research and Training, KU Leuven university, Leuven, Belgium; ²BEAMS Department, Université Libre de Bruxelles, Brussels, Belgium; ³Department of Materials and Production, Aalborg University, Aalborg, Denmark

ENHANCING OSSEOINTEGRATION USING COMPLEX POROUS STRUCTURES

R. Asbai-Ghoudan¹, G. Nasello², M. Á. Pérez³, S. Ruiz de Galarreta¹, N. Rodriguez-Florez¹

¹TECNUN/Universidad de Navarra, Spain; ²KU Leuven, Belgium; ³Universidad de Zaragoza, Spain

AUTOMATICALLY DESIGNED PATIENT-SPECIFIC INSTRUMENTATION FOR TOTAL ANKLE REPLACEMENT: AN IN-VITRO STUDY

M. Conconi¹, N. Sancisi¹, A. Leardini², M. Mosca³, S. Caravelli³, C. Belvedere²

¹Dept. of Industrial Engineering, University of Bologna, Italy; ²Movement analysis Laboratory, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; ³II Clinical Department, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

CELL-BASED MODELING OF BIOMECHANICS IN BIOLOGICAL DEVELOPMENT

R. M. H. Merks

Leiden University, Netherlands, The

MECHANICAL MODELING OF CEREBELLAR FOLIATION CAUSED BY MULTICELLULAR ACTIVITIES

Y. Kameo¹, H. Takeda², T. Adachi¹

¹Kyoto University, Japan; ²Kobe University, Japan

COMPUTATIONAL INSIGHTS INTO MECHANICAL CHANGES IN BACTERIALLY INFECTED CELL MONOLAYERS

R. Aparicio-Yuste^1,2, M. Muenkel², M. T. Sánchez³, E. E. Bastounis², M. J. Gomez-Benito¹

¹Multiscale in Mechanical and Biological Engineering (M2BE), University of Zaragoza, Spain; ²Interfaculty Institute of Microbiology and Infection Medicine, Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI, EXC 2124), University of Tübingen, Germany; ³Centro Universitario de la Defensa de Zaragoza, Zaragoza, 50090, Spain

REMODELING OF 3D MATERIALS VIA A COMBINATION OF THE HOMOGENIZED CONSTRAINED MIXTURE THEORY WITH PLASTICITY

F. Sempertegui, S. Avril

Mines Saint-Étienne, France

COMPUTATIONAL MODELS OF PERITONEAL DIALYSIS

S. Swapnasrita¹, J. de Vries², C. Oberg³, K. G. Gerritsen², A. Carlier¹

¹Maastricht University, Maastricht, the Netherlands; ²Universitair Medisch Centrum, Utrecht, the Netherlands; ³Lund University, Sweden

CONTACT AREA AND CONTACT PRESSURE IN KNEE IMPLANTS: COMPARISON OF DIFFERENT TESTING AND FE METHODS

J.-B. Weiß¹, H. Bächle¹, S. Krüger¹, T. M. Grupp^1,2

¹Aesculap AG, Research & Development, Germany; ²Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, LMU Munich, Munich, Germany

WEAR RATE COMPARISON BETWEEN ADDITIVE MANUFACTURED AND CASTED FEMORAL COMPONENTS

A. L. Puente Reyna¹, J. Schwiesau^1,2, T. M. Grupp^1,2

¹Aesculap AG, Research & Development, Tuttlingen, Germany; ²Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, LMU Munich, Munich, Germany

STRUCTURAL ANALYSIS OF METALLIC ORTHOPAEDIC IMPLANTS BASED ON ASTM STANDARDS: A SOFTWARE COMPARISON STUDY

F. Guidolin, L. Modenese

University of New South Wales, Australia

EFFECT OF DESIGN PARAMETERS IN FB & MB UKA BIOMECHANICS

B. Innocenti¹, E. Bori¹, T. Luyckx²

¹BEAMS Department (Bio Electro and Mechanical Systems), École Polytechnique de Bruxelles, Université Libre de Bruxelles, Bruxelles, Belgium; ²Department of Orthopedic Surgery, AZ Delta, Roeselare, Belgium

KINEMATIC VS MECHANICAL ALIGNMENT IN MEDIALLY-STABILISED TKA: A MATCHED-PAIRS KINEMATIC ANALYSIS

O. Taylan¹, D. Shah¹, F. Dandois¹, W. Han², P. Van Overschelde³, L. Scheys^1,4

¹Institute for Orthopaedic Research and Training (IORT), KU Leuven, Belgium; ²Department of Orthopaedics, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China; ³Hip and Knee Unit, AZ Maria Middelares, Gent, Belgium; ⁴Division of Orthopaedics, University Hospitals Leuven, Belgium

VALIDATION OF A KNEE FINITE ELEMENT MODEL FOR THE DEVELOPMENT OF SURGICAL TRAINING MODELS

K. J. Bennett¹, P. Foroutan¹, E. Fairweather¹, R. Al-Dirini¹, S. Martelli², S. A Sobey³, N. Litchfield³, M. Roe³, K. J Reynolds¹, J. J Costi¹, M. Taylor¹

¹Medical Device Research Institute, Flinders University, Australia; ²Centre for Biomedical Technologies, Queensland University of Technology, Australia; ³Fusetec, Australia

HOW BIOMECHANICS IS CHANGING WOUND CARE: CURRENT ACHIEVEMENTS AND FUTURE PROSPECTS

A. Gefen

Tel Aviv University, Israel

ON THE MECHANOME OF HUMAN SKIN

E. Mazza^1,2, A. Ehret^1,2, D. Sachs¹, A. Wahlsten¹, A. Stracuzzi^1,2, A. Martyts¹

¹Institute for Mechanical Systems, Department of Mechanical and Process Engineering, ETH Zurich, Switzerland; ²Empa, Swiss Federal Lab. for Materials Science and Technology, Dübendorf, Switzerland

DERMAL FIBROBLASTS FEEL AND RESPOND TO PHYSIOLOGICAL MECHANICAL CUES IN VITRO

A. Martyts¹, A. Stracuzzi², D. Al-Nuaimi¹, A. Kourouklis¹, F. Pramotton², D. Sachs¹, C. Giampietro^1,2, E. Mazza^1,2

¹Institute for Mechanical Systems, Department of Mechanical and Process Engineering, ETH Zürich, Zürich, Switzerland; ²EMPA, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf, Switzerland

INVESTIGATION OF GENDER-SPECIFIC RISKS OF SKIN FOLDING AFTER BARIATRIC SURGERY: A COMPUTATIONAL APPROACH

J. Ralvoni^1,2, F. P. T. Baaijens^1,2, S. Loerakker^1,2

¹Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; ²Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands

PROTECTING THE SKIN OF PATIENTS WHO ARE POSITIONED SUPINE OR PRONE

M. Lustig, A. Gefen

Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel

MAXIMUM ARM ELEVATION INVOLVES DIFFERENT SPINOPELVIC MOBILISATION MECHANISMS IN THE ASYMPTOMATIC POPULATION

L. Gajny¹, M.-M. Lefèvre-Colau^2,3,4, R. Ogier³, A. Roby-Brami^3,5, A. Roren^2,3,4

¹Arts et Metiers Institute of Technology, France; ²Université Paris Cité; ³APHP – GH Cochin; ⁴Centre of research in epidemiology and statistics; ⁵Sorbonne université

MULTIBODY KINEMATIC OPTIMIZATION OF SCAPULAR KINEMATICS: THE EFFECT OF MARKER WEIGHTS

F. Lefebvre^1,2, I. Rogowski¹, N. Long², Y. Blache¹

¹Univ Lyon, Université Claude Bernard Lyon 1, Laboratoire Interuniversitaire de Biologie de la Motricité, EA 7424, F-69622 Villeurbanne, France; ²TRINOMA, Villefort, France

GAIT EVENTS DETECTION IN ABSENCE OF THE TOES' AND HEELS' POSITION

M. Hatamzadeh^1,2, L. Busé², R. Zory¹

¹Université Côte d’Azur, LAMHESS, Nice, France; ²Université Côte d’Azur, INRIA, Sophia Antipolis, France

COMPARISON BETWEEN TWO FACE MOBILITY INDEXES FOR HYPOMIMIA ASSESSMENT IN PARKINSON’S DISEASE

E. Pegolo¹, G. Boldrini¹, L. Ricciardi², Z. Sawacha^1,3

¹Department of Information Engineering, University of Padova, Italy; ²Molecular and Clinical Sciences Research Institute, St. George’s University, London, UK; ³Department of Medicine, University of Padova, Padova, Italy

AN INTELLIGENT ALGORITHM TO PREDICT MOVEMENTS AND POSTURES IN SPINAL CORD INJURED PATIENTS

S. Caggiari¹, S. Fryer^1,2, P. Worsley¹

¹School of Health Sciences, University of Southampton, United Kingdom; ²Salisbury NHS Foundation Trust, Salisbury District Hospital, Salisbury, Wiltshire, UK

MECHANOBIOLOGY OF CANCER PROGRESSION

M. T. Raimondi

Dept. of Chemistry, Materials and Chemical Engineering "G.Natta", Politecnico di Milano, Italy

CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION

L. Orlová¹, J. Gumulec², J. Burša¹

¹Brno University of Technology, Department of Biomechanics, Czech Republic; ²Masaryk University, Department of Pathophysiology, Brno, Czech Republic

AN INTEGRATED FINITE ELEMENT AND AGENT-BASED MODEL TO ANALYSE MECHANOSENSITIVE TUMOUR GROWTH

I. Senthilkumar^1,2,3, E. Howley^1,3, E. McEvoy²

¹School of Computer Science, University of Galway, Ireland; ²Discipline of Biomedical Engineering, University of Galway, Ireland; ³Data Science Institute, University of Galway, Ireland

MIGRATION AND TRACTION FORCE CHARACTERIZATION OF PANCREATIC DUCTAL ADENOCARCINOMA CELLS ON STIFFNESS-TUNABLE SUBSTRATES

S. Gabetti¹, S. Marino¹, G. Serino¹, C. Vaghi², M. Tosini¹, A. L. Audenino¹, A. Fiorio Pla², T. Ohashi³, D. Massai¹

¹PoliToBIOMedLab and Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy; ²Department of Life Sciences and Systems Biology, Università di Torino, Italy; ³Faculty of Engineering, Hokkaido University, Sapporo, Japan

DATA-DRIVEN 3D TRACTION FORCE MICROSCOPY IN FIBRILLAR HYDROGELS

J. Barrasa Fano¹, A. Apolinar Fernández², P. Pérez Alcántara², I. Muntz³, G. Koenderink³, J. A. Sanz Herrera², H. Van Oosterwyck¹

¹KU Leuven, Belgium; ²Universidad de Sevilla; ³TU Delft

MULTISCALE MODELLING OF BONE BIOMECHANICS - THE STRUCTURAL ROLES OF MINERAL AND ORGANIC CONSTITUENTS

T. Vaughan

University of Galway, Ireland

MINERAL CONTENT AND MECHANICAL PROPERTIES OF CEMENT LINES IN HUMAN OSTEONAL BONE

A. Cantamessa¹, S. Blouin², S. Amini³, M. Rummler³, A. Berzlanovich⁴, R. Weinkamer³, M. A. Hartmann², D. Ruffoni¹

¹University of Liège, Belgium; ²Ludwig Boltzmann Institute of Osteology, Austria; ³Max Planck Institute of Colloids and Interfaces, Germany; ⁴Center of Forensics Medicine, Austria

BONE COLLAGEN TENSILE PROPERTIES OF THE AGEING HUMAN PROXIMAL FEMUR

S. D. Bracher, B. Voumard, M. Simon, P. Zysset

University of Bern - ARTORG Center for Biomedical Engineering Research, Switzerland

MECHANICAL ENVIROMENT AROUND OSTEOCYTES DURING PHYSIOLOGICAL LOADING

A. Munoz, A. De Paolis, L. Cardoso, A. Carriero

The City College of New York, United States of America

MINERAL MOBILIZATION NEAR THE LACUNAR AND CANAL NETWORK IN LACTATION

M. Sieverts¹, C. Yee², M. Nemani², T. Alliston², C. Acevedo¹

¹University of Utah, United States of America; ²University of California San Francisco, United States of America

A PHYSICS INFORMED NEURAL NETWORK TO SIMULATE THE FREE BOUNDARY PROBLEM OF CELL MIGRATION

S. Malla¹, S. Roy², D. Oelz³

¹UQIDAR, Indian Institute of Technology, Delhi, India.; ²Department of Applied Mechanics, Indian Institute of Technology, Delhi, India.; ³School of Mathematics and Physics, University of Queensland, Australia.

A preliminary 3D finite element study of cell-substrate interaction in microgravity conditions

A. Pica^1,2, A. Marinozzi³, F. Marinozzi¹, F. Bini¹

¹Sapienza University of Rome, Italy; ²University of Sassari, Italy; ³Università Campus Bio-Medico di Roma, Italy

BIOMECHANICAL STUDY ON ADDITIVELY MANUFACTURED NITINOL PATIENT-MATCHED DEVICE FOR UNICORONAL CRANIOSYNOSTOSIS

C. Bregoli¹, A. Borghi^2,3,4, J. Fiocchi¹, C. A. Biffi¹, S. Schievano^3,4, N. U. O. Jeelani^3,4, D. Dunaway^3,4, A. Tuissi¹

¹National Research Council (CNR), Italy; ²Department of Engineering, Durham University, UK; ³GOS Institute of Child Health, University College London, UK; ⁴Great Ormond Street Hospital, UK

BIOMECHANICAL PARAMETER PREDICTS SUCCESSFUL FETAL HEART INTERVENTION OUTCOME BETTER THAN CLINICAL SCANS

L. Green¹, W. X. Chan¹, A. Tulzer², G. Tulzer², C. H. Yap¹

¹Imperial College London, United Kingdom; ²Children's Heart Centre Linz, Austria

EFFECT OF MECHANICAL AORTIC VALVES ON CORONARY ARTERY FLOW IN A PATIENT SUFFERING FROM ISCHEMIC HEART DISEASE

A. Nieroda, K. Jankowski, M. Pawlikowski

Warsaw University of Technology, Poland

MIXED UNIFORM BOUNDARY CONDITIONS IMPROVE HOMOGENIZED FE MODELS OF BONE-SCREWS AND INVERSE REMODELLING

D. Pahr

TU Wien, Austria

Virtual cohort generation for in silico trials of transcatheter aortic valve implantation

S. C. F. P. M. Verstraeten¹, M. J. M. M. Hoeijmakers², F. N. van de Vosse¹, W. Huberts^1,3

¹Eindhoven University of Technology, Netherlands, The; ²ANSYS, The Netherlands; ³Maastricht University, The Netherlands

COLLAGEN-MATRIX WRAP REDUCES CONTACT PRESSURE IN MENISCAL TEAR REPAIR: AN FEA STUDY.

R. Readioff¹, J. Murray², H. Gill¹

¹University of Bath, United Kingdom; ²Avon Orthopaedic Centre, Southmead Hospital North Bristol NHS Trust, Bristol, UK

MODELLING HEMODYNAMICS WITH REAL PHYSIOLOGICAL CONDITIONS OF PATIENT-SPECIFIC CORONARIES

M. C. Fernandes^1,2, L. C. Sousa^1,2, C. C. António^1,2, S. I. Pinto^1,2

¹Engineering Faculty, University of Porto, Porto, Portugal; ²Institute of Science and Innovation in Mechanical and Industrial Engineering, Portugal

IMPACT OF RESISTANCE DISTRIBUTION AND PRESSURE MEASUREMENT IN THE COMPUTED FFR

S. I. Pinto^1,2, A. Martins^1,2, C. C. António^1,2, L. C. Sousa^1,2

¹Engineering Faculty of University of Porto, Portugal; ²Institute of Science and Innovation in Mechanical and Industrial Engineering, Portugal

MINERAL DENSITY AND MICROSTRUCTURAL MORPHOLOGY OF WOVEN BONE DURING DISTRACTION OSTEOGENESIS

J. Mora-Macías¹, B. Van Rietbergen², P. Blázquez-Carmona³, P. García- Florencio⁴, J. Domínguez⁵, E. Reina-Romo⁶

¹University of Huelva, Spain; ²Eindhoven University of Technology, The Netherlands; ³University of Seville, Spain; ⁴University of Seville, Spain; ⁵University of Seville, Spain; ⁶University of Seville, Spain

DXA-driven pipeline for building biofidelic FEMs for hip fracture risk assessment in clinical cohorts

D. Jha^1,2, A. Baker², A. Fung², V. S. Cheong^1,2, N. Hong³, I. Fleps², Y. Rhee³, P. Gupta⁴, E. L. Lamoureux^4,5, S. J. Ferguson^1,2, B. Helgason^1,2

¹ETH Singapore SEC Ltd, Singapore; ²ETH-Zürich, Switzerland; ³Yonsei University College of Medicine, South Korea; ⁴Singapore Eye Research Institute, Singapore; ⁵Duke-NUS Medical School, Singapore

NUMERICAL AND EXPERIMENTAL APPROACH FOR EVALUATING THE RELIABILITY OF CERVICAL SURGICAL INSTRUMENTATION

L. Ciriello¹, A. Belluzzo¹, A. Grassi¹, T. Villa^1,2

¹Department of Chemistry, Materials and Chemical Engineering “Giulio Natta” - LaBS, Politecnico di Milano (Italy); ²IRCCS Istituto Ortopedico Galeazzi (Italy)

MODELING AND SIMULATION OF AN OSTEOCYTE CELLULAR PROCESS INTERACTING WITH FLUID FLOW IN A CANALICULUS

L. Zhu

Indiana University - Purdue Univiersity Indianapolis, United States of America

Effect Of Aortic Valve Geometry On Leaflet Strain Within A Phantom Silicone Aortic Heart Valve During Closing.

T. J. Pritchard, M. Darcy, J. Davies, E. Geeves, L. Giron, C. Ling, R. van Loon, H. Arora

Swansea University, United Kingdom

Patient-specific analysis of the haemodynamic factors contributing to restenosis in peripheral arterial disease

F. Ninno^1,2, A. Dardik^3,4, D. Strosberg^3,4, J. Tsui^5,6, S. Balabani^2,7, V. Diaz-Zuccarini^2,7

¹Dept of Med Physics and Biomedical Engineering, UCL; ²Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), University College London, United Kingdom; ³Yale University School of Medicine, USA; ⁴Dept of Surgery, VA Connecticut Healthcare Systems, USA; ⁵Dept of Vascular Surgery, Royal Free Hospital, UK; ⁶Division of Surgery & Interventional Science, UCL, UK; ⁷Dept of Mechanical Engineering, UCL, UK

EXPLORING THE MECHANISMS OF GROWTH PLATE DEVELOPMENT AND DISEASE PROGRESSION THROUGH A DYNAMIC TRABECULAR BONE MICROSTRUCTURE MODEL

D. Quexada

Université de technologie de compiègne, France

CHARACTERISATION OF THE PHANTOM TISSUE MODELS FOR MEDICAL DEVICE TESTING AND SURGICAL TRAINING

S. Sattar, T. Pritchard, P. Dorrington, R. van Loon, H. Arora

Swansea University, United Kingdom

Fracture toughness of cancellous bone tissues used for the manufacturing of heterologous bone grafts

J. Agnelli¹, M. Morroni², M. Colombo², L. Treccani³, F. Bignotti¹, F. Baldi¹

¹University of Brescia, Italy; ²Bioteck S.p.A., Italy; ³CSMT Gestione S.c.a.r.l., Italy

Damage propagation in osteon-inspired structures: the role of the cement line

T. Volders¹, L. Zorzetto², H. Razi³, R. Weinkamer², D. Ruffoni¹

¹University of Liege, Belgium; ²Max Planck Institute of Colloids and Interfaces, Germany; ³ETH Zurich,Switzerland, and WoodTec Group, Cellulose & Wood Materials Laboratory, Empa, Switzerland

INVESTIGATING BUBBLE DYNAMICS IN A BLOOD-FILLED CAVITY ENCLOSED IN A BLOOD VESSEL

I. Kaykanat, K. Uguz

Bogazici University

CORRECTING THE EJECTION FRACTION FOR BETTER HEART FUNCTION REPRESENTATION AND PROGNOSIS IN HEART FAILURE

W. X. Chan¹, A. Kaura², A. Mulla², D. Papadimitriou², B. Glampson², E. Mayer^2,4, A. S V Shah^2,3, J. Mayet², C. H. Yap¹

¹Imperial College London, United Kingdom; ²UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College London and Imperial College Healthcare NHS Trust; ³Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine; ⁴Department of Surgery & Cancer, Imperial College London

AN ITERATIVE REGULARISATION ALGORITHM TO ESTIMATE PERMEABILITY IN MYOCARDIAL PERFUSION

T. Zhang, K. Fraser, H. Gill, A. Cookson

University of Bath, United Kingdom

PHENOMENOLOGICAL PREDICTION OF FALSE LUMEN THROMBOSIS IN TYPE B AORTIC DISSECTION

A. Jafarinia¹, C. H. Armour², X. Y. Xu², T. Hochrainer¹

¹Graz University of Technology, Austria; ²Imperial College London, London

FLOW VISUALISATION AND SIMULATION IN REALISTIC ANEURYSMS GEOMETRIES TO DETERMINE THE RISK OF RUPTURE

C. Escobar-del Pozo¹, A. Brambila-Solórzano², G. J. Martínez-Sánchez², J. Naude², A. García-Rebolledo¹, V. H. Castillo¹

¹Universidad de Colima, Mexico; ²Universidad Nacional Autónoma de México, México

INVESTIGATING BUBBLE DYNAMICS IN A BLOOD-FILLED CAVITY ENCLOSED IN A BLOOD VESSEL

I. Kaykanat, K. Uguz

Bogazici University

A SYNTHETIC EMBRYONATED AVIAN EGGSHELL COMPUTATIONAL MODELED TO PREDICT THE OXYGEN TRANSPORT

C. Conci¹, L. Cherubin¹, M. Laganà², E. Jacchetti¹, M. Raimondi¹

¹Politecnico di Milano, Dip Chimica Mat e Ing. Chimica G.Natta, Italy; ²Gemma Prototipi, Italy

INTRACRANIAL ANEURYSMS: WHAT ARE YOU MISSING IF YOU CONSIDER FULLY RIGID ARTERIAL TISSUES?

A. Goetz, P. Jeken-Rico, R. Nemer, A. Larcher, P. Meliga, E. Hachem

PSL Mines Paris, CFL Research Group at CEMEF, Sophia Antipolis, 06904, France

SPATIALLY VARYING MULTI-COMPARTMENT MODEL OF BLOOD FLOW AND OXYGEN TRANSPORT IN THE HUMAN BRAIN

S. J. Payne

National Taiwan University, Taiwan

SENSITIVITY OF INTRACRANIAL HAEMODYNAMICS TOWARDS VARYING ARTERIAL TREE EXTENSIONS

P. Jeken Rico, A. Goetz, J. Viquerat, P. Meliga, A. Larcher, E. Hachem

Mines Paris - PSL, France

INFLUENCE OF FLUID-STRUCTURE INTERACTION IN A MODEL OF ATHEROMA PLAQUE GROWTH

P. Hernández-López¹, M. Cilla^1,2, E. Peña^1,2, M. Malvè^2,3, M. A. Martinez^1,2

¹University of Zaragoza, Spain; ²Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Spain; ³Public University of Navarra (UPNA), Pamplona, Spain

INVESTIGATING THE GROWTH & REMODELING MODEL PARAMETERS INFLUENCE ON A HYPERELASTIC ARTERY

K. Yan¹, W. Ye², M. Rochette³, P. Haigron⁴, A. Bel-Brunon⁵

¹ANSYS France, INSA Lyon, LaMCoS ,69100 Villeurbanne; ²ANSYS France; ³ANSYS France; ⁴Univ. de Rennes 1, CHU Rennes, Inserm, France; ⁵Univ Lyon, INSA Lyon, CNRS, LaMCoS, UMR5259, 69621 Villeurbanne, France

CORRECTING THE EJECTION FRACTION FOR BETTER HEART FUNCTION REPRESENTATION AND PROGNOSIS IN HEART FAILURE

W. X. Chan¹, A. Kaura², A. Mulla², D. Papadimitriou², B. Glampson², E. Mayer^2,4, A. S V Shah^2,3, J. Mayet², C. H. Yap¹

¹Department of Bioengineering, Imperial College London, United Kingdom; ²UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College London and Imperial College Healthcare NHS Trust; ³Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine; ⁴Department of Surgery & Cancer, Imperial College London

ON THE ANISOTROPY OF THE MYOCARDIUM

N. Tueni^1,2, J.-M. Allain^1,2, M. Genet^1,2

¹LMS,Ecole Polytechnique, France; ²Inria, France

A NUMERICAL WORKFLOW TO INVESTIGATE THE HEMODYNAMICS EFFECTS OF THE LEFT ATRIAL APPENDAGE OCCLUSION

B. M. Fanni¹, E. Gasparotti¹, K. Capellini¹, F. Danielli², F. Berti², S. Berti³, G. Pennati², L. Petrini⁴, S. Celi¹

¹BioCardioLab, Fondazione Toscana Gabriele Monasterio, Italy; ²LaBS, Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Italy; ³Department of Cardiology, Fondazione Toscana Gabriele Monasterio, Italy; ⁴Department of Civil and Environmental Engineering, Politecnico di Milano, Italy

MECHANICAL FUNCTION IN THE INFARCTED HEART SUPPORTED BY A REGENERATIVE ASSIST DEVICE: A COMPUTATIONAL STUDY

K. Janssens, M. van der Knaap, P. Bovendeerd

Eindhoven University of Technology, The Netherlands

NOVEL PATIENT-SPECIFIC BEATING HEART MODEL INCORPORATING ACTIVE CONTRACTILITY AND A PSEUDO-FLUID DOMAIN

D. Senthil, J. Concannon, J. P. McGarry

University of Galway, Ireland

CONTRAST AGENT TRANSPORT IN A POROELASTIC MODEL OF MYOCARDIAL PERFUSION

T. Zhang, K. Fraser, H. Gill, A. Cookson

University of Bath, United Kingdom

CARDIAC OUTPUT INFLUENCE ON THE FLOW IN A TRI-LEAFLET MECHANICAL HEART VALVE

L. Ferrari

University of Bern, Switzerland

THE INFLUENCE OF THE POSITION ANGLE OF THE ARTIFICIAL BILEAFLET VALVE ON THE FLOW IN THE CORONARY ARTERIES

K. Jankowski, A. Nieroda, M. Pawlikowski

Warsaw University of Technology, Poland

INVESTIGATION OF HUMAN MITRAL VALVE MECHANICS USING AN INHOUSE HYBRID PHYSICAL-COMPUTATIONAL PLATFORM

S. Javadpour¹, F. O'Brien^1,2, C. Conway^1,2

¹Royal College of Surgeons in Ireland, Dublin, Ireland; ²Trinity College Dublin, Dublin, Ireland

EFFECT OF AORTIC VALVE GEOMETRY ON LEAFLET STRAIN WITHIN A PHANTOM SILICONE AORTIC HEART VALVE DURING CLOSING.

T. Pritchard, M. Darcy, J. Davies, E. Geeves, L. Giron, C. Ling, R. van Loon, H. Arora

Swansea University, United Kingdom

EFFECT OF MECHANICAL AORTIC VALVES ON CORONARY ARTERY FLOW IN A PATIENT SUFFERING FROM ISCHEMIC HEART DISEASE

A. Nieroda, K. Jankowski, M. Pawlikowski

Warsaw University of Technology, Poland

BIOMECHANICAL PARAMETER PREDICTS SUCCESSFUL FETAL HEART INTERVENTION OUTCOME BETTER THAN CLINICAL SCANS

L. Green¹, W. X. Chan¹, A. Tulzer², G. Tulzer², C. H. Yap¹

¹Imperial College London, United Kingdom; ²Children's Heart Centre Linz, Austria

COMBINING BIG DATA WITH CELL CULTURE ON THE 3D NICHOID TO DISCOVER NEW THERAPEUTIC STRATEGIES AGAINST CANCER

C. Testa^1,2, E. Jacchetti², C. Martinelli², P. Pinoli¹, S. Carelli³, S. Ceri¹, M. T. Raimondi²

¹DEIB, Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy; ²Department of Chemistry, Materials and Chemical Engineering “Giulio Natta”, Politecnico di Milano, Milano, Italy; ³Pediatric Research Center “Romeo ed Enrica Invernizzi”, Department of Biomedical and Clinical Sciences, University of Milano, Milano, Italy

A PRELIMINARY 3D FINITE ELEMENT STUDY OF CELL-SUBSTRATE INTERACTION IN MICROGRAVITY CONDITIONS

A. Pica^1,2, A. Marinozzi³, F. Marinozzi¹, F. Bini¹

¹Department of Mechanical and Aerospace Engineering, “Sapienza” University of Rome, Italy; ²Department of Biomedical Sciences, University of Sassari, Italy; ³Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Italy

THERAPEUTIC EFFECT OF MECHANICAL LOADING ON BONE METASTASIS: A HCA MODELLING FRAMEWORK

C. Villette¹, L. Geris^1,2

¹KU Leuven, Belgium; ²University of Liège, Belgium

A 3D MECHANOREGULATORY BONE HEALING MODEL COMBINING PATIENT-SPECIFIC GEOMETRY AND INDIVIDUAL LOADING DATA

A. Bäumchen¹, M. Roland¹, M. Orth², T. Pohlemann², B. Ganse³, S. Diebels¹

¹Applied Mechanics, Saarland University, Germany; ²Department of Trauma, Hand and Reconstructive Surgery, Saarland University, Germany; ³Werner Siemens Endowed Chair of Innovative Implant Development (Fracture Healing), Saarland University, Germany

CELL SPREADING ON FIBROUS MATRIX PREDICTED BY HYBRID CELLULAR POTTS MODEL WITH DYNAMIC ADHESIONS

K. A. E. Keijzer, T. Erika, R. M. H. Merks

Leiden University, The Netherlands

MODELING THE REACTION OF A LIVING CELL CYTOSKELETON TO MECHANICAL STRESS IN A FLOWING LIQUID

N. J. Branecka, M. Pawlikowski

Warsaw University of Technology, Poland

MODELING AND SIMULATION OF AN OSTEOCYTE CELLULAR PROCESS INTERACTING WITH FLUID FLOW IN A CANALICULUS

J. Barber¹, M. Mukhin², V. Maybruck³, L. Zhu⁴

¹Indiana University - Purdue Univiersity Indianapolis; ²Vanderbilt University; ³University of Colorado Boulder; ⁴Indiana University - Purdue Univiersity Indianapolis

A PHYSICS INFORMED NEURAL NETWORK TO SIMULATE THE FREE BOUNDARY PROBLEM OF CELL MIGRATION

S. Malla¹, S. Roy², D. Oelz³

¹UQIDAR, Indian Institute of Technology, Delhi, India; ²Department of Applied Mechanics, Indian Institute of Technology, Delhi, India.; ³School of Mathematics and Physics,University of Queensland, Australia.

A 3-DIMENSIONAL MULTIPHASE SMOOTH MUSCLE CELL MODEL EXHIBITING ANISOTROPY & VISCOELASTICITY

A. Marousis, Y. Dimakopoulos, J. Tsamopoulos

University of Patras, Greece

USING A STATISTICAL SHAPE MODEL TO ESTIMATE THE KNEE JOINT CENTER FOR ALIGNING FEMURAL FINITE ELEMENT MODELS

F. Eggermont, E. Mathijssen, M. Bakker, E. Tanck

Orthopaedic Research Lab, Radboud university medical center, Nijmegen, The Netherlands

AGE- AND SEX-SPECIFIC EPIDEMIOLOGY OF EXTRA-ARTICULAR FEMORAL AND TIBIAL FRACTURES 2005-2022

M. Heyland¹, M. Leskovar³, D. Deppe², K. Ziegeler², S. Zachow³, A. Trepczynski¹

¹Julius Wolff Institute, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Germany; ²Department of Radiology, Charité – Universitätsmedizin Berlin, Campus Mitte, Germany; ³Zuse Institute Berlin (ZIB), Berlin, Germany

DXA-DRIVEN PIPELINE FOR BUILDING BIOFIDELIC FEMS FOR HIP FRACTURE RISK ASSESSMENT IN CLINICAL COHORTS

D. Jha^1,2, A. Baker², A. Fung², V. S. Cheong^1,2, N. Hong³, I. Fleps², Y. Rhee³, P. Gupta⁴, E. L. Lamoureux^4,5, S. J. Ferguson^1,2, B. Helgason^1,2

¹Singapore-ETH Centre, Singapore; ²ETH-Zürich, Switzerland; ³Yonsei University College of Medicine, South Korea; ⁴Singapore Eye Research Institute, Singapore; ⁵Duke-NUS Medical School, Singapore

MULTI MODALITY APPROACH FOR OPTIMIZING PROPHYLACTIC AUGMENTATION OF THE PROXIMAL FEMUR FOR HIP FRACTURE PREVENTION

G. Samaras, A. Baker, A. Fung, S. J. Ferguson, B. Helgason

ETH Zurich, Switzerland

VALIDATION OF A FRACTURE HEALING ALGORITHM ACROSS MULTIPLE FIXATION STABILITIES

G. Morgan¹, L. Low¹, A. Ramasamy^1,2, S. Masouros¹

¹Department of Bioengineering, Imperial College London, London, UK; ²Academic Department of Trauma and Orthopaedics, Royal Centre for Defence Medicine, ICT Centre, Birmingham, UK

VIRTUAL COHORT GENERATION FOR IN SILICO TRIALS OF TRANSCATHETER AORTIC VALVE IMPLANTATION

S. C. F. P. M. Verstraeten¹, M. J. M. M. Hoeijmakers², F. N. van de Vosse¹, W. Huberts^1,3

¹Eindhoven University of Technology, The Netherlands; ²ANSYS, The Netherlands; ³Maastricht University, The Netherlands

AN UNCERTAINTY QUANTIFICATION OF IN-SILICO TRIALS FOR THE USE CASE OF NON-UNION TREATMENT

M. Roland¹, K. Wickert¹, A. Andres¹, B. Braun², T. Histing², S. Diebels¹

¹Applied Mechanics, Saarland University, Germany; ²University Hospital Tuebingen, On behalf of the Eberhard-Karls-University Tuebingen, Faculty of Medicine, Department of Trauma and Reconstructive Surgery, BG Hospital Tuebingen, Germany

MODELLING THE INITIAL CALLUS PHASE IN BONE FRACTURES

J. M. Naveiro^1,2, L. Gracia^1,2, J. Roces³, J. Albareda^4,5, S. Puértolas^1,2

¹Universidad de Zaragoza, Spain; ²Aragón Institute for engineering Research; ³Department of Construction and Manufacturing Engineering. University of Oviedo; ⁴Department of surgery, University of Zaragoza; ⁵Aragón Health Research Institute

SCALABLE AGENT-BASED MODELLING OF CELL BIOMECHANICS AND THERAPY USING THE BIODYNAMO PLATFORM

V. Vavourakis^1,2, R. Bauer³

¹University of Cyprus, Cyprus; ²University College London, UK; ³University of Surrey, UK

CELL PROLIFERATION STUDY: A NEW COMPUTATIONAL MODEL SOLVED BY THE SPH METHOD

M. I. Barbosa¹, J. Belinha², R. Natal Jorge³, A. Xavier de Carvalho⁴

¹Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI), Portugal; ²School of Engineering Polytechnic of Porto (ISEP), Portugal; ³Faculty of Engineering of University of Porto (FEUP), Portugal; ⁴Institute for Research and Innovation in Health (I3S), Portugal

SIMULATION OF ANGIOGENESIS DURING TUMOUR GROWTH PROLIFERATION

M. I. Barbosa¹, J. Belinha², R. Natal Jorge³, A. Xavier de Carvalho⁴

¹Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI), Portugal; ²School of Engineering Polytechnic of Porto (ISEP), Portugal; ³Faculty of Engineering of University of Porto (FEUP), Portugal; ⁴Institute for Research and Innovation in Health (I3S), Portugal

EXPLORING THE MECHANISMS OF GROWTH PLATE DEVELOPMENT AND DISEASE PROGRESSION THROUGH A DYNAMIC TRABECULAR BONE MICROSTRUCTURE MODEL

D. Quexada^1,2, S. Bensamoun¹, M.-C. Ho Ba Tho¹, D. Garzón², O. Trabelsi¹

¹Université de Technologie de Compiègne; ²Universidad Nacional de Colombia

COLLAGEN-MATRIX WRAP REDUCES CONTACT PRESSURE IN MENISCAL TEAR REPAIR: AN FEA STUDY.

R. Readioff¹, J. Murray², H. Gill¹

¹Department of Mechanical Engineering, University of Bath, Bath, UK.; ²Avon Orthopaedic Centre, Southmead Hospital North Bristol NHS Trust, Bristol, UK

PARAMETRIC STUDY OF MECHANICAL BEHAVIOR OF AUXETIC GEOMETRIES FOR SKIN TISSUE ENGINEERING SCAFFOLDS

O. Lecina, M. Á. Pérez, C. Borau

Universidad de Zaragoza, Spain

ANATOMICAL RISK FACTORS INCREASING PATHOLOGICAL GROWTH IN CRANIOSYNOSTOSIS

M. Geoffroy^1,2,3, P.-M. François², R. H. Khonsari³, S. Laporte¹

¹Arts et Métiers Institute of Technology, France; ²BONE 3D, France; ³Hôpital Necker - Enfants Malades AP-HP, Université de Paris

TRANSCATHETER MITRAL VALVE REPLACEMENT: ASSESSMENT OF LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION

J. Brüning^1,2, K. Vellguth^1,2, J. Franz^1,2, C. Balemans³, M. Barink³, M. Oude Vrielink³, V. Lavezzo³

¹Deutsches Herzzentrum der Charité; Institute for Cardiovascular, Computer-assisted Medicine; ²Charité - Universitätsmedizin Berlin, Germany; ³Philips Research, AI, Data Science and Digital Twin department, The Netherlands

VIRTUAL TREATMENT PLANNING OF TRANSCATHETER EDGE-TO-EDGE MITRAL VALVE REPAIR

M. Barink¹, K. Vellguth^2,3, J. Franz^2,3, J. Brüning^2,3, V. Lavezzo¹

¹Philips Research, AI, Data Science and Digital Twin department, The Netherlands; ²Deutsches Herzzentrum der Charité, Institute of Computer-assisted Cardiovascular Medicine, Germany; ³Charité - Universitätsmedizin Berlin, Germany

DEVELOPMENT OF DIGITAL TWINS FROM HIGH-FIDELITY SIMULATIONS FOR HEALTHCARE APPLICATIONS

L. Geronzi^1,2, A. Martinez^1,2, M. Rochette², M. E. Biancolini¹

¹University of Rome Tor Vergata, Department of Enterprise Engineering "Mario Lucertini”, Rome, Italy; ²Ansys France, Villeurbanne, France

SUCTION CUP PLACEMENT IN INSTRUMENTED VAGINAL DELIVERY

D. Oliveira¹, E. Ferreira²

¹INEGI, LAETA & FEUP, Portugal; ²FEUP, Portugal

SIMULATION OF MAXIMUM ELBOW FLEXION, EXTENSION, PRONATION AND SUPINATION ACTUATION TORQUES BASED ON ZONOTOPES

J. SAVIN¹, N. REZZOUG^2,3

¹INRS, France; ²PPrime Institute, CNRS-University of Poitiers-ENSMA, UPR 3346, France; ³Equipe projet AUCTUS, INRIA, France

A BIOMECHANICAL MODEL TO TEST THE EFFECTS OF A PASSIVE EXOSKELETON ON THE SHOULDER COMPLEX

A. Ayechu Abendaño^1,2, A. Ancillao¹, G. Aronis¹, T. Angeli¹, M. Gföhler¹

¹TU Wien, Austria; ²Universidad de Zaragoza, Spain.

FOREARM MUSCULAR ACTIVITY DURING THE REAL VS VIRTUAL BOX & BLOCK TEST

N. J. Jarque-Bou¹, V. Gracia-Ibáñez¹, A. Roda-Sales¹, A. de los Reyes-Guzmán², J. L. Sancho-Bru¹, M. Vergara¹

¹Departamento de Ingeniería Mecánica y Construcción, Universitat Jaume I, Castellón, Spain; ²Unidad de Biomecánica y Ayudas Técnicas, Hospital Nacional de Parapléjicos, Toledo, Spain

DESIGN AND OPTIMIZATION OF A SIX-BAR LINKAGE TO ASSIST IN THE REHABILITATION OF THE PULP PINCH GRIP IN STROKE PATIENTS

M. Gabarda-Lopez, V. Roda-Casanova, J. Andres-Esperanza, J. L. Iserte, J. F. Fuentes-Ballesteros, N. J. Jarque-Bou

Department of Mechanical Engineering and Construction, Universitat Jaume I, Spain

DESIGN OF UPPER LIMB EXOSKELETON ORTHOSIS FOR REHABILITATION PURPOSES

E. J. O'Sullivan, A. R. Keppel, L. A. Zambrano Martínez

South East Technological University, Ireland

NOVEL THERAPY SETTING BY USING VIRTUAL AND AUGMENTED REALITY– A COMPARATIVE FEASIBILITY STUDY

D. Baumgartner¹, A. Kilchenmann¹, D. Textor¹, J. Bansi²

¹Zurich University of Applied Sciences, Switzerland; ²Kliniken Valens, Switzerland

MIXED UNIFORM BOUNDARY CONDITIONS IMPROVE HOMOGENIZED FE MODELS OF BONE-SCREWS AND INVERSE REMODELLING

D. Pahr^1,2, S. Bachmann¹, A. Synek¹

¹TU Wien, Austria; ²Karl Landsteiner University of Health Sciences, Austria

BIOMECHANICAL STUDY ON ADDITIVELY MANUFACTURED NITINOL PATIENT-MATCHED DEVICE FOR UNICORONAL CRANIOSYNOSTOSIS

C. Bregoli¹, A. Borghi^2,3,4, J. Fiocchi¹, C. A. Biffi¹, S. Schievano^3,4, N. U. O. Jeelani^3,4, D. Dunaway^3,4, A. Tuissi¹

¹National Research Council (CNR-ICMATE), Italy; ²Department of Engineering, Durham University, UK; ³GOS Institute of Child Health, University College London, UK; ⁴Great Ormond Street Hospital, UK

MINERAL DENSITY AND MICROSTRUCTURAL MORPHOLOGY OF WOVEN BONE DURING DISTRACTION OSTEOGENESIS

J. Mora-Macías^1,2, B. V. Rietbergen^3,4, P. Blázquez-Carmona^2,5, P. García-Florencio⁶, J. Domínguez^2,6, E. Reina-Romo^2,6

¹University of Huelva, Spain; ²Institute of Biomedicine of Seville (IBiS); ³Eindhoven University of Technology; ⁴Maastricht University Medical Centre; ⁵University of Cadiz; ⁶University of Seville

FRACTURE TOUGHNESS OF CANCELLOUS BONE TISSUES USED FOR THE MANUFACTURING OF HETEROLOGOUS BONE GRAFTS

J. Agnelli¹, M. Morroni², M. Colombo², L. Treccani³, F. Bignotti¹, F. Baldi¹

¹Università degli Studi di Brescia, Italy; ²Bioteck S.p.A., Italy; ³CSMT Gestione S.c.a.r.l., Italy

DAMAGE PROPAGATION IN OSTEON-INSPIRED STRUCTURES: THE ROLE OF THE CEMENT LINE

T. Volders¹, L. Zorzetto², H. Razi³, R. Weinkamer², D. Ruffoni¹

¹University of Liege, Belgium; ²Max Planck Institute of Colloids and Interfaces, Germany; ³ETH Zurich,Switzerland, and WoodTec Group, Cellulose & Wood Materials Laboratory, Empa, Switzerland

MECHANICAL EVALUATION OF BONE GRAFT ENHANCED OVINE TIBIA BONE DEFECT USING DIGITAL VOLUME CORRELATION

K. Karali¹, A. DeMori², R. Kallala³, G. Blunn²

¹School of Mechanical and Design Engineering, University of Portsmouth, United Kingdom; ²School of Pharmacy and Biomedical Sciences, University of Portsmouth, UK; ³Corthotec Ltd, United Kingdom

A PROTOCOL FOR THE LOCAL MECHANICAL CHARACTERISATION OF METASTATIC BONE

A. Levillain¹, C. B Confavreux^2,3,4, F. Bermond¹, D. Mitton¹, H. Follet²

¹Univ Lyon, Univ Gustave Eiffel, UCBL, LBMC UMR_T9406, Lyon, France; ²Univ Lyon, UCBL, INSERM, LYOS UMR 1033, Lyon, France; ³Hospices Civils de Lyon, Centre hospitalier Lyon Sud, Pierre Bénite, France; ⁴CEMOS, Service de Rhumatologie, Institut de Cancérologie, Lyon, France

THREE PHASES IN BONE TISSUE PROPERTIES FROM MICROMECHANICAL TESTING AT THE MATERIAL LEVEL

A. Bonicelli¹, E. F. Kranioti², B. Xhemali³, P. Zioupos⁴

¹University of Central Lancashire, UK; ²University of Crete, Greece; ³Institute of Forensic Medicine, Albania; ⁴University of Hull, UK

EFFECT OF WEIGHT LOSS ON SUBCHONDRAL BONE CYST IN THE KNEE JOINT DURING GAIT: A 3D FINITE ELEMENT ANALYSIS

J. Dahlgren¹, G. A Orozco¹, L. Stenroth^2,3, T. Alkjær², H. Isaksson¹

¹Lund University, Sweden; ²University of Copenhagen, Denmark; ³University of Eastern Finland, Finland

PRESSURE DISTRIBUTION AT THE DEVICE SKIN INTERFACE OF A CERVICAL COLLAR: FINITE ELEMENT AND PHYSICAL MODELLING

L. J. Russell, L. Jiang, D. Filingeri, P. R. Worsley

University of Southapmton, UK

A NUMERICAL AND EXPERIMENTAL APPROACH FOR EVALUATING THE RELIABILITY OF CERVICAL SURGICAL INSTRUMENTATION

L. Ciriello¹, A. Belluzzo¹, A. Grassi¹, T. Villa^1,2

¹Department of Chemistry, Materials and Chemical Engineering “Giulio Natta” - LaBS, Politecnico di Milano (Italy); ²IRCCS Istituto Ortopedico Galeazzi (Italy)

THE FEASIBILITY OF BESPOKE REHABILITATION ROBOT HANDGRIPS TO MEET THE SPECIFIC NEEDS OF STROKE PATIENTS—PART 2

L. Li, Z. Lu, Y. Tang, S. Tyson, G. Cooper, A. Weightman

The University of Manchester, United Kingdom

BIOMECHANICS OF BRAIDED, LONG-TERM BIODEGRADABLE SCAFFOLDS FOR ACL TISSUE ENGINEERING

C. Emonts, P. Riedl, B. Bauer, T. Gries

Institut für Textiltechnik, RWTH Aachen University, Germany

A SAWBONE BASED BIOMECHANICAL STUDY TO COMPARE COMPRESSION FORCE AND OSSEOUS AREA OF CONTACT OF TWO SCREWS FOR FOOT AND ANKLE JOINT ARTHRODESIS

A. Weigert, M. Kistler, L. Bauer, B. Holzapfel, B. Wegener

MUM-Muskuloskelettales UniversitätsZentrum LMU München, Germany

UTILISING A 3D FE MODEL TO ASSESS THE EFFECTS OF ANATOMY ON STRESS/STRAIN DISTRIBUTION IN OSSEOINTEGRATED IMPLANTS

T. McGuire, A. M J Bull

Imperial College London, United Kingdom

ADJUSTMENT OF PROSTHETIC SOCKET USING FINITE ELEMENT ANALYSIS

A. Mrozek

Poznan University of Technology, Poland

CLINICAL PERSPECTIVE OF DEVELOPING ROBOTIC SYSTEMS FOR ASSISTING PERCUTANEOUS TRACHEOSTOMY

Y. Tang¹, L. Li¹, P. Yuan¹, Z. Lu¹, B. Adorno², B. McGrath³, A. Weightman¹

¹Department of Mechanical, Aerospace and Civil Engineering, University of Manchester, United Kingdom; ²Department of Electrical and Electronic Engineering, University of Manchester, United Kingdom; ³Manchester University NHS Foundation Trust, United Kingdom

NUMERICAL MODEL OF THE MECHANICAL BEHAVIOUR OF MEDICAL COMPRESSION STOCKINGS

I. Pita Miguélez, D. Soulat, X. Legrand, A. R. Labanieh

Laboratoire GEMTEX, ENSAIT Roubaix - Université de Lille, France

INSOLE: AN IN-SILICO TOOL TO PREDICT INDIVIDUAL RESPONSE TO CORRECTIVE INSOLES DURING WALKING.

B. A. Killen¹, S. Van Rossom², F. Burg², I. Jonkers¹

¹Department of Movement Science, KU Leuven, Belgium; ²Materialise Motion, Materialise NV, Belgium

VARIABLE ROTATIONAL SPEED SUBSTANTIALLY REDUCE THE RATE OF HEMOLYSIS WITHIN IN-HOUSE ROLLER PUMP

J. Kohut, J. Jagos, M. Formanek, J. Bursa

Brno University of Technology, Czech Republic

MODELLING BIOFILM GROWTH SUBJECT TO LOCAL ANTIBIOTIC DELIVERY

P. Mandal, N. Mottram, S. McGinty

University of Glasgow, United Kingdom

BIOMECHANICAL DETERMINANTS OF CHONDROLABRAL COMPLEX LESIONS IN FEMOROACETABULAR IMPINGEMENT

I. Lazarev¹, A. Babko², M. Skyban²

¹OTH Regensburg, Germany; ²Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine

A MATLAB TOOL TO SCALE ITERATIVELY AND AUTOMATICALLY GENERIC MUSCULOSKELETAL MODELS

A. Di Pietro¹, F. Di Puccio^1,2

¹Department of Civil and Industrial Engineering, University of Pisa, Italy; ²Center for Rehabilitative Medicine “Sport and Anatomy”, University of Pisa, Italy

LOWER LIMB AMPUTEES HAVE SIMILAR UPPER LIMB FUNCTION 8Y POST INJURY AS UNINJURED GROUP: THE ADVANCE COHORT STUDY

F. C E Watson¹, A. E Kedgley¹, A. Bennett², A. M J Bull¹

¹Imperial College London, United Kingdom; ²The Defence Medical Rehabilitation Centre, United Kingdom

MUSCULOSKELETAL MULTIBODY SIMULATION OF PAEDIATRIC PATIENTS BEFORE AND AFTER FEMUR OSTEOTOMY

L. Ruehrmund¹, N. Moeller¹, H. Boehm², C. Fritz³, U. Schreiber⁴, D. Vogel¹, R. Bader¹, M. Kebbach¹

¹Department of Orthopaedics, Rostock University Medical Center, Rostock, Germany; ²Orthopedic Children’s Hospital, Kind im Zentrum – Chiemgau, Aschau, Germany; ³School of Engineering and Design, Technical University of Munich, Munich, Germany; ⁴OT Medizintechnik GmbH, Munich, Germany

SIMULATION OF LOWER LIMB MUSCLE ACTIVATION USING RUNNING SHOES WITH DIFFERENT HEEL-TO-TOE DROPS USING OPENSIM

W. Quan^1,2, X. Jiang^1,3, D. Xu^1,2, H. Zhou^1,4, G. Fekete⁵, Y. Gu¹

¹Ningbo University, China, Faculty of Sports Science; ²University of Pannonia, Hungary,Department of Materials Engineering; ³Óbuda University, Hungary, Doctoral School on Safety and Security Sciences; ⁴University of the West of Scotland, United Kingdom,School of Health and Life Sciences; ⁵Eötvös Loránd University, Hungary,Savaria Institute of Technology

EMG-BASED JOINT TORQUE ESTIMATION USING PHYSICS-INFORMED NEURAL NETWORK IN HUMAN UPPER LIMB

R. Kumar¹, S. Roy¹, L. Kumar², S. P. Muthukrishnan³

¹Dept. of Applied Mechanics, Indian Institute of Technology Delhi, India; ²Dept. of Electrical Engineering, Indian Institute of Technology Delhi, India; ³Dept. of Physiology, All India Institute of Medical Sciences, New Delhi, India

NEW AUTOMATED ALGORITHM FOR MUSCLE ARCHITECTURE EXTRACTION FROM B-MODE ULTRASOUND IMAGES

E. Karakasis¹, E. Giannakou¹, A. Arampatzis², K. Vadikolias¹, N. Aggelousis¹

¹Democritus University of Thrace, Greece; ²Humboldt Universität zu Berlin, Germany

SIMULATION ENVIRONMENT FOR THE DEVELOPMENT OF NEURO-MUSCULAR STIMULATION SYSTEMS

S. Selkmann, J. Baier, R. Remus, M. Neumann, B. Bender

Chair of Product Development, Department of Mechanical Engineering, Ruhr-University Bochum, Germany

COMPUTATIONAL SIMULATION OF THE ACTIVE BEHAVIOUR OF MOUSE ROTATOR CUFF MUSCLES

Á. Heras¹, A. Pérez Ruíz^2,3, G. Abizanda^2,3, B. Calvo^1,4, J. Grasa^1,4

¹University of Zaragoza, Spain; ²University of Navarra (UNAV), Spain; ³Instituto de Investigación Sanitaria de Navarra (IdiSNA), Spain; ⁴Bioengineering, Biomaterials and Nanomedicine Networking Biomedical Research Centre (CIBER-BBN)

WHICH ARE THE MINIMUM ACTIVITIES OF DAILY LIVING TO REPRESENT FOREARM MUSCLE ACTIVITY?

N. J. Jarque-Bou, V. Gracia-Ibañez, A. Roda-Sales, J. L. Sancho-Bru, M. Vergara

Departamento de Ingeniería Mecánica y Construcción, Universitat Jaume I, Spain

MULTI-SCALE CORONARY SIMULATION PIPELINE: VALIDATION AGAINST INTRAVASCULAR VELOCITY AND PRESSURE

A. A. Seresti¹, A. L. Marsden², A. M. Kahn³, M. O. Khan¹

¹Department of Electrical, Computer and Biomedical Engineering, Toronto Metropolitan University, Canada; ²Department of Pediatrics, Stanford University, Stanford, CA, USA; ³Division of Cardiovascular Medicine, University of California San Diego, La Jolla, CA, USA

TUNING PATIENT-SPECIFIC CORONARY LUMPED PARAMETER MODELS IN PRESENCE OF SEVERE AORTIC STENOSIS

D. Fernández-Martínez¹, J. M. Nogales-Asensio², M. R. González-Fernández², C. Ferrera¹

¹Department of Mechanical, Energy and Materials Engineering,University of Extremadura, Spain; ²Hemodynamics and Interventional Cardiology Section, University Hospital of Badajoz, Spain

PATIENT-SPECIFIC ANALYSIS OF THE HAEMODYNAMIC FACTORS CONTRIBUTING TO RESTENOSIS IN PERIPHERAL ARTERIAL DISEASE

F. Ninno^1,2, A. Dardik^3,4, D. Strosberg^3,4, J. Tsui^5,6, S. Balabani^2,7, V. Diaz-Zuccarini^2,7

¹Dept of Med Physics and Biomedical Engineering, UCL, UK; ²Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), UCL, UK; ³Yale University School of Medicine, USA; ⁴Dept of Surgery, VA Connecticut Healthcare Systems, USA; ⁵Dept of Vascular Surgery, Royal Free Hospital, UK; ⁶Division of Surgery & Interventional Science, UCL, UK; ⁷Dept of Mechanical Engineering, UCL, UK

IMPACT OF RESISTANCE DISTRIBUTION AND PRESSURE MEASUREMENT IN THE COMPUTED FFR

S. I. Pinto^1,2, A. Martins¹, C. C. António^1,2, L. C. Sousa^1,2

¹Engineering Faculty of University of Porto, Porto, Portugal; ²Institute of Science and Innovation in Mechanical and Industrial Engineering, Porto, Portugal

LUMPED-PARAMETER MODEL TO ASSESS CORONARY BLOOD FLOW IN AAOCA: A FOCUS ON THE IMPACT OF BOUNDARY CONDITIONS

V. Ceserani¹, M. Lo Rito², G. M. Formato³, M. L. Agnifili⁴, A. Rosato³, A. F. Pascaner¹, M. Conti¹

¹DICAr, University of Pavia, Italy; ²Department of Congenital Cardiac Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Italy; ³3D and Computer Simulation Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Italy; ⁴Department of Clinical and Interventional Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy

EFFICIENT SENSITIVITY ANALYSIS FOR BIOMECHANICAL MODELS WITH CORRELATED INPUTS

P. L. J. Hilhorst¹, S. Quicken¹, F. N. van de Vosse¹, W. Huberts^1,2

¹Eindhoven University of Technology, the Netherlands; ²CARIM School for Cardiovascular Diseases, Maastricht, the Netherlands

MODELLING HEMODYNAMICS WITH REAL PHYSIOLOGICAL CONDITIONS OF PATIENT-SPECIFIC CORONARIES

M. C. Fernandes^1,2, L. C. Sousa^1,2, C. C. António^1,2, S. I. Pinto^1,2

¹Engineering Faculty, University of Porto, Porto, Portugal; ²Institute of Science and Innovation in Mechanical and Industrial Engineering, Porto, Portugal

AORTIC HEMODYNAMICS EVALUATION BASED ON REDUCED ORDER MODELS: EFFECT OF INLET CONDITIONS

F. Galbiati^1,2, C. Angeletti³, K. Capellini³, E. Vignali³, C. Morin², S. Avril², E. Costa¹, S. Celi³

¹RINA Consulting S.p.A., Italy; ²Mines Saint Etienne, INSERM, SAINBIOSE U1059, F-42023, Saint-Étienne, France; ³BioCardioLab, Fondazione Toscana Gabriele Monasterio, Massa, Italy

ON THE NEED OF A RELIABLE NUMERICAL MODEL TO SIMULATE THE LEFT ATRIAL APPENDAGE OCCLUSION: A FINITE ELEMENT STUDY

F. Danielli¹, F. Berti¹, B. M. Fanni², E. Gasparotti², S. Celi², G. Pennati¹, L. Petrini³

¹Department of Chemistry, Materials and Chemical Engineering "Giulio Natta" (CMIC), Politecnico di Milano; ²BioCardioLab, Fondazione Toscana Gabriele Monasterio (FTGM), Italy; ³Department of Civil and Environmental Engineering (DICA), Politecnico di Milano

PERSONALISED COMPUTATIONAL MODELS TO STUDY THE IMPACT OF COVID-19 LUNGS UNDER MECHANICAL VENTILATION

D. Kernot, J. Carson, R. van Loon, H. Arora

Department of Biomedical Engineering, Swansea University, United Kingdom

COMPARING THE STIFFNESS OF THE SKIN TO THAT OF COMMONLY USED SKIN-CONTACTING MEDICAL DEVICES IN CONTEXT OF MDRPU

A. Orlov¹, O. Belo¹, S. Solmos², J. Cuddigan², M. Lustig³, A. Gefen¹

¹Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Israel; ²University of Nebraska Medical Center, NE, USA; ³Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel

CHARACTERISATION OF THE PHANTOM TISSUE MODELS FOR MEDICAL DEVICE TESTING AND SURGICAL TRAINING

S. Sattar, T. Pritchard, P. Dorrington, R. van Loon, H. Arora

Swansea University, United Kingdom

EXPERIMENTAL ANALYSIS OF PLANTAR SKIN

S. Pettenuzzo, A. Berardo, E. Belluzzi, A. Pozzuoli, P. Ruggieri, E. L. Carniel, C. G. Fontanella

Univeristy of Padova, Italy

USE OF AGAR SAMPLES TO MIMIC THE ELECTROMECHANICAL PROPERTIES OF HUMAN BURN SKIN

R. MATTHIEU^1,2, E. SCHALL^1,2,3, A. BALDIT^1,2, A.-S. BONNET^1,2, M.-R. LOSSER^3,4, S. LE TACON⁴

¹LEM3-UMR-7239, CNRS - Université de Lorraine - Arts et Métiers ParisTech, France; ²ENIM, Université de Lorraine, France; ³INSERM U1116-DCAC, Université de Lorraine, France; ⁴Centre Hospitalier Régional Metz-Thionville, France

COMPRESSION TEXTILES AND SKIN IRRITATION: A CLINICAL STUDY

B. Eydan¹, D. Rimaud², P. Calmels², J.-J. Perrot², R. Convert³, H. Zahouani⁴, B. Pierrat¹, J. Molimard¹

¹Mines Saint-Etienne, Univ Lyon, Univ Jean Monnet, INSERM, U 1059 Sainbiose, Centre CIS, Saint-Étienne, France; ²Hôpital Nord, CHU de Saint-Etienne, France; ³Thuasne, BP243, 92307 Levallois-Perret cedex, France; ⁴Laboratoire de Tribologie et Dynamique des Systèmes, UMR 5513, CNRS, ECL, ENISE, Saint Etienne, France

IN-VIVO DETERMINATION OF PRE-STRESS AND TENSION LINES IN SKIN

H. Conroy Broderick¹, M. Destrade², W. Shu¹, A. Ní Annaidh¹

¹University College Dublin, Ireland; ²University of Galway, Ireland

A COMPARATIVE STUDY ON THE BIOMECHANICAL PROPERTIES OF PORCINE MENISCUS IN CONFINED COMPRESSION

L. de Roy¹, A. Morejon², A. R. Jackson², F. Travascio^2,3, A. M. Seitz¹

¹Institute of Orthopaedic Research and Biomechanics, University Ulm, Germany; ²Department of Mechanical Engineering, University of MiamiUniversity of Miami, USA; ³Max Biedermann Institute for Biomechanics at Mount Sinai Medical Center, USA

EXPERIMENTAL ASSESSMENT OF MECHANICAL CHANGES IN HUMAN OSTEOARTHRITIC CARTILAGE

A. Berardo^1,2, C. G. Fontanella³, I. Toniolo¹, G. Mazzucco¹, E. Belluzzi⁴, A. Pozzuoli⁴, P. Ruggieri⁴, E. L. Carniel³

¹Department of Civil, Environmental and Architectural Engineering, University of Padova, Italy; ²Department of Biomedical Sciences, University of Padova, Italy; ³Department of Industrial Engineering, University of Padova, Italy; ⁴Orthopedics and Orthopedic Oncology, DiSCOG, University of Padova, Italy

AGE INFLUENCE ON CUT-OUT RESISTANCE OF SUTURED MENISCUS: AN EXPERIMENTAL CADAVERIC STUDY

A. Peña-Trabalon, M. B. Estebanez-Campos, S. Moreno-Vegas, A. Perez-Blanca, M. Prado-Novoa

Clinical Biomechanics Laboratory of Andalusia (BIOCLINA), University of Malaga, Spain

PARAMETRIC ANALYSIS OF GEOMETRIC VARIANCE IN ARTICULAR CARTILAGE SAMPLE BIOMECHANICS USING FINITE ELEMENT

V. Jönsson, G. A. Orozco, L. Grassi, H. Isaksson

Department of Biomedical Engineering, Lund University

NON-INVASIVE MRI-BASED CHARACTERIZATION OF CARTILAGE DEGRADATION USING VIRTUAL FIELDS METHOD

I. Mohout¹, S. A. Elahi¹, L. Maes², P. Vandemaele², N. Famaey², I. Jonkers¹

¹Human Movement Biomechanics, KU Leuven, Belgium; ²Soft tissue biomechanics, KU Leuven, Belgium

REDUCTION OF STRAIN CLUSTERS IN INJURED HEEL FINITE ELEMENT MODELS WITH A NEW PRESSURE ULCER DRESSING

N. Fougeron¹, G. Chagnon¹, N. Connesson¹, T. Alonso¹, L. Pasquinet², S. Auguste², A. Perrier^1,3, Y. Payan¹

¹Univ. Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000 Grenoble, France; ²Urgo Research, Innovation & Development, 21300, Chenôve, France; ³Sorbonne Université Médecine; Assistance publique Hôpitaux de Paris (APHP), Service de Diabétologie, Hôpital Pitié-Salpêtrière

ASCENDING AORTIC ANEURYSM GROWTH PREDICTION BASED ON MACHINE LEARNING AND SHAPE FEATURES DERIVED FROM 3D SLICER

L. Geronzi^1,2, A. Martinez^1,2, P. Haigron³, A. Bel-Brunon⁴, M. Rochette², P. P. Valentini¹, M. E. Biancolini¹

¹University of Rome Tor Vergata, Department of Enterprise Engineering ``Mario Lucertini”, Rome, Italy; ²Ansys France, Villeurbanne, France; ³University of Rennes, CHU Rennes, Inserm, LTSI – UMR 1099, F-35000, Rennes, France; ⁴University of Lyon, INSA Lyon, CNRS, LaMCoS, UMR5259, 69621 Villeurbanne, France

INTER-SPECIES DIFFERENCES IN PULMONARY ARTERY MORPHOMETRY AND HEMODYNAMICS

J. Brüning^1,2, N. Krüger^1,2, P. Yevtushenko^1,2, L. Goubergrits^1,2

¹Deutsches Herzzentrum der Charité; Institute for Cardiovascular, Computer-assisted Medicine; ²Charité - Universitätsmedizin Berlin, Germany

INTEGRATION OF REAL-TIME SIMULATIONS AND AUGMENTED REALITY FOR CATHETER MONITORING DURING PERCUTANEOUS PROCEDURES

V. Ruozzi, P. Vassena, M. C. Palumbo, A. Caimi, A. Redaelli, E. De Momi, E. Votta

Politecnico di Milano, Italy

MACHINE LEARNING AND REDUCED ORDER MODELLING FOR THE SIMULATION OF BRAIDED STENT DEPLOYMENT

B. Bisighini^1,2,3, M. Aguirre^1,4,5, B. Pierrat¹, D. Perrin², S. Avril¹

¹École des Mines de Saint-Étienne, France; ²Predisurge, Saint-Étienne, France; ³Università Tor Vergata, Rome, Italy; ⁴Laboratori de Calcul Numeric, Universitat Politecnica de Catalunya, Barcelona, Spain; ⁵International Centre for Numerical Methods in Engineering (CIMNE), Barcelona, Spain

STICKING TOGETHER: COMPUTATIONAL MODELLING OF CELL-CELL AND CELL-MATRIX INTERACTIONS

A. Carlier

Maastricht University, Belgium

YAP/TAZ AND MECHANICAL CUES AS TEMPORAL REGULATORS OF ANGIOGENESIS

M. M. Passier¹, K. Bentley², S. Loerakker¹, T. Ristori¹

¹Eindhoven, University of Technology, Netherlands, The; ²Francis Crick Institute, United Kingdom

A TWO-PHASE HAEMODYNAMIC MODEL FOR ARTERIAL MICROVASCULAR BIFURCATIONS

T. Wisitponchai^1,2, J. Wu¹, A. Kazakidi¹

¹Department of Biomedical Engineering, University of Strathclyde, Glasgow, UK; ²Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand

MODELLING MIDLINE SHIFT AND VENTRICLE COLLAPSE IN POST-STROKE CEREBRAL OEDEMA

X. Chen¹, T. I. Józsa^1,2, S. J. Payne^1,3

¹Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, United Kingdom; ²Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Amsterdam, Netherlands; ³Institute of Applied Mechanics, National Taiwan University, Taiwan

TOWARDS MODELLING COLD-WATER CORAL REEF CRUMBLING

M. Peña Fernández¹, S. Henninge², U. Wolfram¹

¹School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, United Kingdom; ²Changing Oceans Research Group, School of GeoSciences, University of Edinburgh, Edinburgh,United Kingdom

CONSIDERING MIXED EPISTEMIC AND ALEATORIC UNCERTAINTY IN THE STRUCTURAL VALIDATION OF A SAPIEN-3 TAVI FEM-MODEL

N. Götzen¹, O. Zahalka¹, T. Turgut¹, S. Pasta², V. Bouwman¹

¹4RealSim Services BV, Netherlands, The; ²University of Palermo, Italy

EFFECT OF THE LUMBAR BELT ON TRUNK MOBILITY: A COMPARATIVE CLINICAL STUDY

A. ERRABITY^1,2, J. P. Vasco Marin¹, R. Bonnaire³, W.-S. Han¹, R. Pannetier², R. Convert², P. Calmels⁴, J. Molimard¹

¹Mines Saint-Etienne, Univ Jean Monnet, INSERM, U 1059 Sainbiose, Centre CIS, Saint-Etienne France; ²Thuasne, BP243, 92307 Levallois-Perret cedex, France; ³Institut Clément Ader (ICA), Université de Toulouse, CNRS, IMT Mines Albi, INSA, ISAE-SUPAERO, UPS Campus Jarlard, F-81013 Albi, France; ⁴Hôpital Nord, CHU de Saint-Etienne, France

INVESTIGATING CERVICAL COLLAR DESIGN AND FIT: INTERFACE PRESSURE AND DISCOMFORT

L. J. Russell, L. Jiang, D. Filingeri, P. R. Worsley

University of Southapmton, UK

FINITE ELEMENT MODEL FOR THE TREATMENT OF PLAGIOCEPHALY BY CRANIAL ORTHESIS.

G. Vallois¹, E. Marty¹, C. Cavinato², F. Jourdan²

¹Lagarrigue, France; ²LMGC, Université de Montpellier, CNRS, France

A PIPELINE FOR MECHANOBIOLOGY-DRIVEN DESIGN OF SCAFFOLD

M. J. A. Bedding-Tyrrell, F. Zhao

Swansea University, United Kingdom

SENSORISED CHILD WALKER FOR THE ASSESSMENT OF REHABILITATION THERAPIES

M. B. Estebanez Campos¹, J. M. Velasco Garcia¹, A. Peña Trabalon¹, S. Moreno Vegas¹, F. Nadal Martinez¹, F. Garcia Vacas¹, A. Perez de la Blanca¹, M. Prado Novoa¹, M. Ceccarelli²

¹UNIVERSITY OF MALAGA, Spain; ²UNIVERSITY OF ROME TOR VERGATA, Italy

METABOLIC ANALYSIS OF A WEARABLE UPPER LIMB EXOSKELETON FOR OVERHEAD WORK

G. Aronis¹, A. Ancillao¹, T. Del Grossi², T. Angeli¹, M. Gföhler¹

¹TU Wien, Austria; ²Politecnico di Milano,Italy

BENDING RESPONSE OF A SOFT ACTUATOR FOR A WEARABLE HAPTIC DEVICE

A. D. André^1,2, P. Martins^2,3, M. Taghavi⁴

¹FEUP, Portugal; ²INEGI-LAETA, Portugal; ³i3A, University of Zaragoza, Spain; ⁴Imperial College London, United Kingdom

ESTIMATION OF INTERSEGMENTAL LOAD AT L5-S1 DURING LIFTING/LOWERING TASK WITH MARKERLESS MOTION CAPTURE

J. JIANG^1,2, W. Skalli¹, A. Siadat², L. Gajny¹

¹Arts et Metiers Institute of Technology, Institut de Biomecanique Humaine Georges Charpak, France; ²Arts et Metiers Institute of Technology, Laboratoire de Conception Fabrication Commande, France

EFFECTS OF AN ACTIVE BACK-SUPPORTING EXOSKELETON ON KINEMATICS DURING LIFTING AND CARRYING LOADS

H. Wackerle^1,2, J. Bruckhuber^1,3, P. Augat^1,2

¹Institute for Biomechanics, BG Unfallklinik Murnau, Germany; ²Institute for Biomechanics, Paracelsus Medical University Salzburg, Austria; ³Department of Industrial Engineering and Health, Technical University of Applied Sciences, Amberg-Weiden, Germany

SENSOR-BASED CONTINUOUS ASSESSMENT OF POSTOPERATIVE SHOULDER ACTIVITY

M. Herteleer¹, A. Runer^2,3, M. Remppis⁴, J. Schlatter⁴, J. Brouwers¹, F. Schneider², V. C. Panagiotopoulou⁴, B. Grimm⁵, C. Hengg², R. Arora², S. Nijs^1,6, P. Varga⁴

¹University Hospitals Leuven, Belgium; ²Medical University Innsbruck, Austria; ³Technical University of Munich, Germany; ⁴AO Research Institute Davos, Switzerland; ⁵Luxembourg Institute of Health, Luxembourg; ⁶University Medical Center Utrecht, The Netherlands

BUILDING AN ECOSYSTEM FOR DIGITAL TWINS IN HEALTHCARE

L. Geris

KU Leuven

IN SILICO CLINICAL TRIAL TO PREDICT THE EFFICACY OF HIP PROTECTORS FOR PREVENTING HIP FRACTURES

S. Oliviero^1,2, A. A. La Mattina^1,2, A. Aldieri^2,3, G. Savelli^1,2, M. Viceconti^1,2

¹Department of Industrial Engineering, University of Bologna, Italy; ²Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; ³Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy

STRATIFYING HIP FRACTURE RISK IN THE FULL AGES REYKJAVIK COHORT USING FINITE ELEMENT MODELLING

A. D. Praveen¹, A. Baker², D. Jha^1,2, I. Fleps¹, P. Bjornsson³, S. Sigurdsson⁴, L. M. Ellingsen³, V. S. Cheong¹, V. Gudnason⁴, S. J. Ferguson^1,2, H. Palsson³, B. Helgason^1,2

¹Singapore ETH Centre, Singapore; ²Institute for Biomechanics, ETH Zurich, Zurich, Switzerland; ³University of Iceland, Reykjavik, Iceland; ⁴The Icelandic Heart Association, Kopavogur, Iceland

USING BIOFIDELIC FEMS TO QUANTIFY THE EFFICACY OF INVASIVE PROPHYLACTIC TREATMENTS FOR HIP FRACTURE PREVENTION

A. Fung, A. Baker, R. Langenegger, G. Samaras, S. J. Ferguson, B. Helgason

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland

ENDOSCOPIC STRIP CRANIECTOMY WITH HELMET THERAPY: A COMPUTATIONAL TOOL FOR PREDICTION OF HEAD RESHAPING

L. Deliege¹, A. Carriero², S. Schievano¹, J. Ong³, G. James³, O. Jeelani³, D. Dunaway³, M. Bookland⁴, A. Borghi⁵

¹University College of London, UK; ²City College of New York, US; ³Great Ormond Street Hospital, UK; ⁴Connecticut Children’s Hospital, US; ⁵Durham University, UK

MECHANOBIOLOGY FOR CLINICAL CANCER PROGNOSIS: CONTEMPORARY SCIENCE AND FUTURE, APPLICATIVE PROSPECTS

D. Weihs

Technion-Israel Institute of Technology, Israel

GENERATION OF TRANSGENIC MICE EXPRESSING FRET-BASED TENSION SENSOR: MASUREMENT WITH CONVENTIONAL CLSM

T. Matsumoto¹, J. Wang¹, E. Maeda¹, Y. Tsujimura², H. Yokota², T. Kitaguchi³

¹Nagoya University, Japan; ²RIKEN Center for Advanced Photonics, Japan; ³Tokyo Institute of Technology, Japan

3D PHOTOPOLYMERIZED SCAFFOLD PORE SIZE REGULATES MESENCHYMAL STEM CELL PHENOTYPE

E. Jacchetti¹, T. Baldissera¹, B. Barzghini¹, L. Messa^2,3, C. Cereda⁴, S. Carelli^2,4, M. Raimondi¹

¹Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Italy.; ²Pediatric Research Center "Romeo ed Enrica Invernizzi", Department of Biomedical and Clinical Sciences, University of Milano, Milano, Italy; ³Department of Electronics, Information and Bioengineering, Politecnico di Milano, Italy; ⁴Center of Functional Genomics and Rare Diseases, Buzzi Childen's Hospital, Milano, Italy

THE CONTRIBUTION OF LOWER-MINERALIZED TISSUE TO THE STRENGTH OF FRACTURED DISTAL RADII DURING HEALING

M. Bevers^1,2, F. Heyer¹, C. Wyers¹, P. Geusens³, H. Janzing¹, O. Lambers Heerspink¹, M. Poeze³, J. van den Bergh¹, B. van Rietbergen²

¹VieCuri Medical Center, Netherlands, The; ²Eindhoven University of Technology, Netherlands, The; ³Maastricht University Medical Center, Netherlands, The

PREDICTING FEMORAL STRENGTH FROM 2D-3D DXA FINITE ELEMENT MODELS ACROSS AGE AND ETHNICITIES

V. S. Cheong^1,2, D. Jha^1,2, A. Baker², L. Grassi³, N. Hong⁴, K. A Greene⁵, A. A Weaver⁵, S. Väänänen⁶, Y. Rhee⁴, H. Isaksson³, S. J Ferguson^1,2, B. Helgason^1,2

¹Singapore-ETH Centre, Singapore; ²Institute for Biomechanics, ETH Zürich, Switzerland; ³Department of Biomedical Engineering, Lund University, Sweden; ⁴Department of Internal Medicine, Yonsei University College of Medicine, South Korea; ⁵Department of Biomedical Engineering, Wake Forest University School of Medicine, USA; ⁶Department of Technical Physics, University of Eastern Finland, Finland

BONE MATERIAL STRENGTH INDEX TO DIFFERENTIATE EARLY BONE STRUCTURE IN PATIENTS AFFECTED BY CRANIOSYNOSTOSIS

S. Ajami^1,2, S. Schievano^1,2, M. Pinedo¹, G. James², J. Ong², D. Dunaway^1,2, N. U. O. Jeelani^1,2, A. Borghi^1,2,3

¹UCL Great Ormond Street Institute of Child Health; ²Great Ormond Street Hospital; ³Durham University, United Kingdom

STATISTICAL MODELS INFORMED BY DXA IMAGES SLIGHTLY OUTPERFORM T-SCORE IN THE PREDICTION OF HIP FRACTURE

A. Aldieri¹, M. Paggiosi², P. Bhattacharya³, R. Eastell², A. L Audenino¹, M. Terzini¹

¹PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Torino, Italy.; ²Department of Oncology and Metabolism University of Sheffield, UK.; ³Department of Mechanical Engineering and INSIGNEO Institute for in silico Medicine, University of Sheffield, UK.

QCT-BASED COMPUTATIONAL BONE STRENGTH ASSESSMENT UPDATED WITH MRI-DERIVED ‘HIDDEN’ MICROPOROSITY

S. McPhee¹, L. Kershaw², C. Daniel³, M. Peña Fernández¹, S. E Taylor³, U. Wolfram¹

¹Institute of Mechanical, Process and Energy Engineering, Heriot-Watt University, UK.; ²Centre for Cardiovascular sciences and Edinburgh Imaging, University of Edinburgh, UK.; ³Royal (Dick) School of Veterinary Studies and Roslin Institute, University of Edinburgh, UK

MINIMAL DETECTABLE FEATURES IN CT IMAGES AND DIGITAL 3D MODELS

M. Frank^1,2, A. Strassl³, E. Unger², L. Hirtler⁴, B. Eckhart¹, M. Koenigshofer², A. Stoegner¹, K. Staats¹, F. Kainberger³, R. Windhager¹, F. Moscato^2,5,6, E. Benca¹

¹Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Austria; ²Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria; ³Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Austria; ⁴Center for Anatomy and Cell Biology, Medical University of Vienna, Austria; ⁵Ludwig Boltzmann Institute for Cardiovascular Research, Austria; ⁶Austrian Cluster for Tissue Regeneration, Austria

LIMB FLEXION INDUCED DEFORMATION OF FEMOROPOPLITEAL ARTERY STENTS IN THIEL EMBALMED CADAVERS

S. Nandan¹, H. D. Simpson³, S. Clark³, C. Voustas³, M. Bernini¹, C. Dunlop², G. Houston³, R. Hellmuth², E. Dolan¹, T. Vaughan¹

¹Biomechanics Research Center, University of Galway, Ireland; ²Vascular Flow Technologies, Dundee, UK; ³Tayside Innovation MedTech Ecosystem, University of Dundee, UK

ROLE OF VASCULAR SMOOTH MUSCLE CELL PHENOTYPE SWITCHING IN THE ROSS PROCEDURE: A COMPUTATIONAL STUDY

L. Maes, T. Vervenne, L. Van Hoof, A. Hendrickx, P. Verbrugghe, F. Rega, E. A. V. Jones, N. Famaey

KU Leuven, Belgium

ON THE IMPACT OF ARTERIAL MODELLING IN CORONARY STENTING SIMULATIONS: A VALIDATED STUDY ON 5 PATIENT-SPECIFIC CASES

G. Poletti¹, L. Antonini¹, G. S. Karanasiou², D. I. Fotiadis², L. Petrini³, G. Pennati¹

¹LaBS - Dept. of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Italy; ²Dept. of Biomedical Research, FORTH-IMBB, GR 45110 Ioannina, Greece; ³Dept. of Civil and Environmental Engineering, Politecnico di Milano, Milan, Italy

ULTRASTRUCTURAL STUDY OF INDUCED VASCULAR DAMAGE CAUSED BY IN VITRO STENTING

G. Sommer¹, M. Pranger², D. Kolb^2,3, G. Leitinger², G. A. Holzapfel^1,4

¹Institute of Biomechanics, Graz University of Technology, Austria; ²Gottfried Schatz Research Center, Medical University Graz, Austria; ³Core Facility Ultrastructure Analysis, Medical University Graz, Austria; ⁴Department of Structural Engineering, Norwegian University of Science and Technology, Norway

HOMOGENIZED FE MODELS CAN PREDICT HIP JOINT LOADING USING INVERSE BONE REMODELING AT THE FEMORAL HEAD

S. Bachmann¹, D. H. Pahr^1,2, A. Synek¹

¹TU Wien, Austria; ²Karl Landsteiner University of Health Sciences, Austria

A PLATFORM FOR IN-SILICO EXPERIMENT OF BONE REMODELING FOR UNDERSTANDING ROLES OF MECHANO-CHEMICAL COUPLINGS

T. Adachi, Y. Kameo

Kyoto University, Japan

IN-SILICO APROACH TO ELUCIDATE THE PATHWAYS LEADING TO PRIMARY OSTEOPOROSIS: AGE-RELATED VS. POSTMENOPAUSAL

R. Ruiz-Lozano¹, J. L. Calvo-Gallego¹, P. Pivonka², J. Martínez-Reina¹

¹University of Seville, Spain; ²Queensland University of Technology, Australia

EFFECT OF THE LOADING DIRECTION ON THE PREDICTED MECHANICAL PROPERTIES OF THE MOUSE TIBIA

S. M. Farage-O'Reilly^1,2,3, V. S. Cheong^2,4, I. Bellantuono^1,2,3, V. Kadirkamanathan^2,5, E. Dall'Ara^1,2,3

¹Department of Oncology and Metabolism, University of Sheffield, UK; ²INSIGNEO Institute of in silico Medicine, UK; ³Healthy Lifespan Institute, UK; ⁴Future Health Technologies, Singapore-ETH Centre, Singapore; ⁵Department of Automatic Controls and Systems Engineering, University of Sheffield, UK

IN SILICO EXPLORATION OF OSTEOPOROSIS DRUG EFFECTS ON BONE ADAPTATION BASED ON REMODELING AND MODELING

Y. K. Kim^1,2, Y. Kameo¹, S. Tanaka², T. Adachi¹

¹Institute for Life and Medical Sciences, Kyoto University, Japan; ²Department of Orthopaedic Surgery, The University of Tokyo, Japan

LIMITATIONS OF HOMOGENIZED FINITE ELEMENTS ANALYSIS OF DISTAL TIBIA SECTIONS

M. Simon¹, M. Indermaur¹, D. Schenk¹, B. Voumard¹, P. Varga², M. Pretterklieber³, P. Zysset¹

¹ARTORG Center for biomedical engineering research, University of Bern, Switzerland; ²AO Research Institute Davos, 7270 Davos, Switzerland; ³Division of macroscopical and clinical Anatomy Medical University of Graz, Graz, Austria

DATA-DRIVEN FSI SIMULATION OF VENTRICLE AND AORTA INTEGRATING IN VIVO AND IN SILICO DATA

M. A. Scarpolini^1,2, G. Piumini³, F. Cademartiri⁴, S. Celi¹, F. Viola⁵

¹BioCardioLab, Fondazione Toscana Gabriele Monasterio, Italy; ²University of Rome “Tor Vergata”, Italy; ³University of Twente, The Netherlands; ⁴Clinical Imaging Department, Fondazione Toscana Gabriele Monasterio, Italy; ⁵GSSI (Gran Sasso Science Institute), L’Aquila, Italy

A CT-BASED DEEP LEARNING SYSTEM FOR AUTOMATIC ASSESSMENT OF AORTIC ROOT MORPHOLOGY FOR TAVI PLANNING

S. Saitta¹, F. Sturla^2,1, R. Gorla², O. Oliva², E. Votta^1,2, F. Bedogni², A. Redaelli¹

¹Politecnico di Milano, Italy; ²IRCCS Policlinico San Donato, Italy

DATA-DRIVEN METHODS FOR PATIENT-SPECIFIC REDUCED ORDER MODELING OF COMPLEX AORTIC FLOWS

C. Chatpattanasiri^1,2, G. Franzetti¹, V. Diaz-Zuccarini^1,2, S. Balabani^1,2

¹Department of Mechanical Engineering, University College London, London, UK; ²Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), Department of Medical Physics and Biomedical Engineering, University College London, London, UK

AORTIC SEGMENTATION VIA SYNTHETIC DATA AUGMENTATION STRATEGY FROM PC-MRI SMALL DATASET

S. Garzia^1,2, M. A. Scarpolini^1,3, M. Mazzoli^1,2, A. Monteleone⁴, F. Cademartiri⁴, S. Celi¹

¹BioCardioLab - Fondazione Toscana Gabriele Monasterio, Italy; ²Department of Information Engineering, University of Pisa, Italy; ³Department of Industrial Engineering, University of Rome "Tor Vergata", Italy; ⁴Clinical Imaging Department, Fondazione Toscana Gabriele Monasterio, Italy

DEEP RESIDUAL AMBIVALENT GRAPH CONVOLUTIONAL NETWORKS FOR BIOMARKER PREDICTION IN LARGE VESSEL NETWORKS

A. B. Drysdale¹, H. Arora¹, A. Davies², R. van Loon¹

¹Swansea University, United Kingdom; ²United Kingdom Atom Energy Authority, Culham Centre for Fusion Energy

IMPLEMENTING DIGITAL TWINS OF THE CARDIOVASCULAR SYSTEM IN CLINICAL SETTINGS: AN AUTOMATED DEEP LEARNING PIPELINE

M. A. Scarpolini^1,2, M. Mazzoli^1,3, S. Garzia^1,3, A. Monteleone⁴, S. Celi¹

¹BioCardioLab, Fondazione Toscana Gabriele Monasterio, Italy; ²University of Rome “Tor Vergata”, Italy; ³Department of Information Engineering, University of Pisa, Italy; ⁴Clinical Imaging Department, Fondazione Toscana Gabriele Monasterio, Italy

DATA-DRIVEN GENERATION OF INLET VELOCITY PROFILES FOR CFD MODELLING IN THORACIC AORTIC ANEURYSMS

S. Saitta¹, L. Maga^1,2, C. H. Armour³, E. Votta¹, D. P. O’Regan³, M. Y. Salmasi³, T. Athanasiou³, J. W. Weinsaft⁴, X. Y. Xu³, A. Redaelli¹, S. Pirola^2,3

¹Politecnico di Milano, Italy; ²Delft University of Technology, The Netherlands; ³Imperial College London, UK; ⁴Weill Cornell College, NY, USA

IN SEARCH OF CARDIOVASCULAR BIOMARKERS FOR PRE-ECLAMPSIA

R. van Loon¹, C. Popp¹, D. Kernot¹, J. Carson¹, H. Arora¹, J. Myers², E. Johnstone²

¹Swansea University, United Kingdom; ²University of Manchester, United Kingdom

MODELLING OF CELL-SCALE HAEMODYNAMICS IN THE MATERNAL INTERVILLOUS SPACE OF HUMAN PLACENTA

Q. Zhou¹, E. Doman², I. L. Chernyavsky^2,3, O. E. Jensen², M. O. Bernabeu^4,5, T. Krüger¹

¹School of Engineering, Institute for Multiscale Thermofluids, The University of Edinburgh, UK; ²Department of Mathematics, The University of Manchester, UK; ³Maternal and Fetal Health Research Centre, School of Medical Sciences, The University of Manchester, UK; ⁴Centre for Medical Informatics, Usher Institute, The University of Edinburgh, UK; ⁵The Bayes Centre, The University of Edinburgh, UK