Conference Agenda

Topical Meetings and Sessions:

TOM 1 - Silicon Photonics and Guided-Wave Optics
TOM 2 - Computational, Adaptive and Freeform Optics
TOM 3 - Optical System Design, Tolerancing and Manufacturing
TOM 4 - Bio-Medical Optics
TOM 5 - Resonant Nanophotonics
TOM 6 - Optical Materials: crystals, thin films, organic molecules & polymers, syntheses, characterization and applications
TOM 7 - Thermal radiation and energy management
TOM 8 - Non-linear and Quantum Optics
TOM 9 - Opto-electronic Nanotechnologies and Complex Systems
TOM 10 - Frontiers in Optical Metrology
TOM 11 - Tapered optical fibers, from fundamental to applications
TOM 12 - Optofluidics
TOM 13 - Advances and Applications of Optics and Photonics
EU Project Session
Early Stage Researcher Session

More information on the Topical Meetings

Select a date or location to show only sessions at that day or location. Select a single session for a detailed view (with abstracts and downloads when you are logged in as a registered attendee). The rest of the TOM sessions, EU project session, tutorials, and Early Stage Researcher session will be updated soon. Thank you for your patience!

Please note that all times are shown in the time zone of the conference. The current conference time is: 11th Aug 2022, 10:39:36pm WEST

Session Overview
TOM12 S02: Optofluidics: Emerging Concepts
Tuesday, 13/Sept/2022:
2:30pm - 4:00pm

Location: Room 3

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2:30pm - 3:00pm
ID: 159 / TOM12 S02: 1
TOM 12 Optofluidics

Heliconical Cholesterics: new opportunities for optofluidics?

Francesco Simoni

ISASI - CNR - Italy, Italy

In this presentation the novelty represented by the heliconical cholesteric liquid crystals (Ch-OH) for easy electric and optical control of optical properties are highlighted. After a quick summary of their electro-optical properties, an account of the recent experimental and theoretical achievements about the nonlinear optical response of Ch-OH will be given. The peculiar conical structure allows an easy control of the spectral location of the Bragg resonance making possible effects never observed previously in pure liquid crystals, making these materials attractive for development of several optical devices.

3:00pm - 3:15pm
ID: 240 / TOM12 S02: 2
TOM 12 Optofluidics

Sized based separation of microparticles with lab-in-a-fiber optofluidic device

Harish Achar Vasant1, Tharagan Kumar2, Walter Margulis3, Aman Russom2, Fredrik Laurell1

1KTH-Royal Institute of Technology, Sweden; 2Division of Nanobiotechnology, Department of Protein Science, Science for Life Laboratory, KTH Royal Institute of Technology, Solna, Sweden; 3Fiber Optics, Photonics and Nano, RISE Research Institutes of Sweden

Separation of cells or microparticles from mixed population based on their size is an important part of biomedical diagnostics. Conventional devices that perform such tasks are often bulky and expensive, limiting their use in remote areas with resource-constrained settings. To address such a challenge we develop a portable, lab-scale prototype “all-fiber” device capable of separating microparticles based on their size. Different kinds of silica fiber capillaries were used to fabricate the separation device in a Vytran glass processing station. We use elasto-inertial fluid dynamics to focus the larger particle to center of the device, while the smaller particles remain unfocused. Through systemic arrangement of fiber capillaries at the collection end we achieve the separation. As a key demonstration, we separated 10 and 1 µm microparticles from a mixed population with a separation efficiency of 100% for the 10 µm and 97% for the 1 µm particles.

3:15pm - 3:30pm
ID: 333 / TOM12 S02: 3
TOM 12 Optofluidics

Trapping, characterization and reactions of biocolloids in a salinity gradient

Martin Kjærulf Rasmussen, Jonas Nyvold Pedersen, Rodolphe Marie

Technical University of Denmark, Denmark

The properties of soft matter nanoparticles like exosomes are interesting for drug delivery and diagnostics applications. However, the simultaneous characterization of multiple properties, e.g., size and zeta potential, can only be done serially and is highly sensitive to the purification prior to characterization. Here we show how a salt gradient established in a nanofluidic channel induces opposing transport of particles and liquid that trap the particles. Particles are thus accumulated in the trap. We show how optical microscopy images of the particle positions in the salinity gradient provide a measurement of the size and surface charge. We demonstrate the method on a sample of exosomes and on individual particles. Finally, we show how biomolecular reactions at the surface of the nanoparticle can be detected from the optical microscopy analysis of the particles’ trapping position

3:30pm - 3:45pm
ID: 326 / TOM12 S02: 4
TOM 12 Optofluidics

Size-based chromosome separation in a microfluidic particle separation device using viscoelastic fluids

Therese Rahbek Wassberg1, Mathilde Lassen Witt1, Murat Serhatlioglu1, Christian Friberg Nielsen2, Ian David Hickson2, Anders Kristensen1

1Technical University of Denmark (DTU), Denmark; 2University of Copenhagen (KU), Denmark

Viscoelastic flow-based particle manipulation techniques enable bio-particle focusing, separation, and enrichment by precisely tuning the rheological parameters, flow conditions, and microchannel geometry. In this study, we fabricated a PDMS-based single inlet/outlet microchannel to separate bio-particles by their size ranging from 1-10 µm. Flow conditions and rheological properties are optimized using 2 µm and 4 µm Polystyrene beads to reach the best particle separation condition. We demonstrated the size-based separation of human chromosomes by separating 1-2 µm size small chromosomes from 8-10 µm size large chromosomes. Thanks to its miniaturized size and simplicity, the isolation chip and unique viscoelastic separation method have great potential to be used as a future pioneering tool for genetic applications to study chromosome abnormalities such as fragile-X and trisomy.

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