Conference Agenda

Topical Meetings and Sessions:

TOM 1 - Silicon Photonics and Guided-Wave Optics
TOM 2 - Computational, Adaptive and Freeform Optics
TOM 3 - Optical System Design, Tolerancing and Manufacturing
TOM 4 - Bio-Medical Optics
TOM 5 - Resonant Nanophotonics
TOM 6 - Optical Materials: crystals, thin films, organic molecules and polymers, syntheses, characterization and devices
TOM 7 - Thermal radiation and energy management
TOM 8 - Nonlinear and Quantum Optics
TOM 9 - Optics at Nanoscale (ONS)
TOM 10 - Optical Microsystems (OMS)
TOM 11 - Waves in Complex Photonic Media
TOM 12 - Optofluidics
TOM 13 - Ultrafast Optical Technologies and Applications
TOM 14 - Advances and Applications of Optics and Photonics
EU Project Session
Early Stage Researcher Session organised by SIOF
Grand Challenges of Photonics Session

More information on the Topical Meetings

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Session Overview
TOM10 S01: Optical Microsystems (OMS): Biosensors & Biochips
Thursday, 16/Sept/2021:
8:15 - 9:45

Session Chair: Ivo Rendina, National Research Council (CNR), Italy
Location: Aula 9

1st Floor

8:15 - 9:00
Special Invited
ID: 290 / TOM10 S01: 1
TOM 10 Optical Microsystems (OMS)

Bioelectronic single-molecule label-free sensing with large-area transducing interfaces

Luisa Torsi

Università Degli Studi di Bari Aldo Moro, Italy

Nanosized bioelectronic sensing interfaces are the privileged choice for single-molecule detections. While giving access to rarer events, they are unsuited to work at low-concentrations. Bioelectronic transistors are perceived as unsuited due to the irrelevant footprint of a single molecule on a much larger detecting interface. Many field-effect biosensors detect below femtomolar. Here the field is reviewed, illustrating device architectures, materials used, and target analytes that can be selectively detected. The sensing mechanisms enabling the large-area bioelectronic sensor to detect at a single-molecule are also detailed.

9:00 - 9:30
ID: 390 / TOM10 S01: 2
TOM 10 Optical Microsystems (OMS)

Development of an ultra sensitive lateral flow immunoassay based on the use of gold nanoprisms to detect prostate cancer derived exosomes

Beatriz Martín-Gracia1,2, Alba Martin-Barreiro1,2, Carlos Cuestas-Ayllón1,2, Valeria Grazu1,2, Jesus M. de la Fuente1,2, Maria Moros1,2

1Instituto de Nanociencia y Materiales de Aragón(INMA), Spain; 2Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN),

Extracellular vesicles (EV) are very interesting as biomarkers to study prostate cancer (PCa) progression.

In this work, we propose the development of an ultrasensitive thermal transduction biosensor based on lateral flow immunoassay (LFIA) and gold nanoprisms as thermal labels. We have been able to detect low amounts of EVs on the LFIA strips, increasing the sensitivity of the biosensor when compared to classical LFIA where non-thermal labels are used. Further, we have been able to differentiate between pools of EVs derived from healthy donors and PCa patients

9:30 - 9:45
ID: 532 / TOM10 S01: 3
TOM 10 Optical Microsystems (OMS)

In-vivo fabrication of bioelectronic interface via polymerization of conjugated oligomers

Giuseppina Tommasini1, Gwennaël Dufil2, Federica Fardella1, Xenofon Strakosas2, Eugenio Fergola1, Tobias Abrahamsson2, David Bliman3, Roger Olsson3,4, Magnus Berggren2, Angela Tino1, Eleni Stavrinidou2, Claudia Tortiglione1

1Istituto di Scienze Applicate e Sistemi Intelligenti “E. Caianiello”, Consiglio Nazionale delle Ricerche, Via Campi Flegrei 34, 80078, Pozzuoli, Italy; 2Laboratory of Organic Electronics, Department of Science and Technology, Linkoping University, SE-60174, Norrkoping, Sweden; 3Department of Chemistry and Molecular Biology, University of Gothenburg, SE-405 30, Gothenburg, Sweden; 4Chemical Biology & Therapeutics, Department of Experimental Medical Science, Lund University, SE-221 84, Lund, Sweden

Leveraging the biocatalytic machinery of living organisms for fabricating functional bioelectronic interfaces, in-vivo, defines a new class of micro-biohybrids enabling the seamless integration of technology with living biological systems. Here, we expand this concept by reporting that Hydra, an invertebrate animal, polymerizes the conjugated oligomer ETE-S resulting in electronically conducting and electrochemically active µm-sized domains, that are fully integrated within the hydra tissue and the secreted mucus.