Conference Agenda
Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
|
Daily Overview |
| Session | |
|
VP: Virtual Prototyping & Digital Twin Location: B8.1.1 Session Chair: Prof. Nicola Cappetti, University of Salerno Session Chair: Dr. Michele Bici, Sapienza University of Rome | |
    | |
Julich Brain Atlas Version Sensitivity in GBM Topologi-cal Mapping Alma Mater Studiorum University of Bologna, Italy Brain atlas selection is rarely treated as an explicit methodological variable in neuroimaging workflows, yet successive releases of probabilistic atlases may differ substantially in their spatial coverage and ontological completeness. This paper examines how the anatomical assignment of a glioblastoma (GBM) lesion changes across five successive versions of the Julich Brain Atlas (v1.18, v2.4, v2.6, v3.0, v3.1) as deployed on the EBRAINS research infrastructure, within the framework of the EU Horizon project DTRIP4H. A single IDH-wildtype GBM case - segmented via MONAI from clinical DICOM data and registered to the MNI ICBM152 reference space - was mapped against each at-las version using labeled maximum probability maps. Volumetric intersection statistics were computed separately for enhancing tumor and necrotic core, without diagnostic or functional inference. Results show that atlas coverage of the tumor volume ranges from 49.8% to 82.4% across versions, with no mono-tonic relationship to release recency. Ontological labeling quality varies inde-pendently, with three versions unsuitable for named-area assignment in their current deployment. Version v3.0 provides the most complete and interpreta-ble output. A potential anatomical discontinuity between v3.0 and v3.1 is doc-umented and discussed. | |