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Index of Titles

A complete list of all conference contributions. Use the alphabetical filter or the search box below to find specific submissions. Click on any contribution to view its session details.

List by Initial Letter: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All Titles

Contribution Title	Author(s)	Session
Abiraterone-derived dual inhibitor targeting CYP17A1 and HDAC6 as a novel strategy to overcome temozolomide resistance in glioblastoma	Lin, Hong-Yi; Hsu, Tsung-I	Symposia 7 P450 Drug Design and targeting
Applications of small angle scattering to delineate P450-membrane and redox partner interactions.	Hackett, John C; Stokowa-Sołtys, Kamila; Zarate-Perez, Francisco	Symposia 6 Catalytic Mechanisms of Cytochrome P450
Assessing the function of a thermophilic CYP152 isolated from a Bacillus species	Gee, Alecia Rachel; Lee, Yu-Jin; Yun, Chul-Ho; Bell, Stephen Graham	Symposia 11 P450 Across Species
Biased P450 activation by controlling P450 oxidoreductase conformational sampling: A single molecule and machine learning perspective	Hatzakis, Nikos	Symposia 4: P450 Biophysics
Biomolecular simulations of Cytochrome P450 enzymes	Kuvek, Tea; Oostenbrink, Chris	Symposia 3: P450 Bioinformatics
Characterization of CYP1750B2 from C. tardaugens NBRC 16725 involved in estrogens degradation: possible applications in green wastewater treatment	Armellino, Francesca; Chiatello, Nicolò; Marucco, Arianna Maria Beatrice; Catucci, Gianluca; Costa, Sabrina; Schilirò, Tiziana; Gilardi, Gianfranco; Di Nardo, Giovanna	Symposia 15: Short Talks by PhD Students
Cofactor-free hydroxylation of aliphatic C–H bonds by bacterial cytochrome P450 and peroxygenase enzymes	Yun, Chul-Ho	Symposia 6 Catalytic Mechanisms of Cytochrome P450
Complexation of cytochrome P450 17A1 with its redox proteins in a membrane: Insights from molecular dynamics simulation	Teuffel, Jonathan; Mukherjee, Goutam; Han, Sungho Bosco; Wade, Rebecca C.	Symposia 15: Short Talks by PhD Students
CRISPR/Cas9-generated POR knockout cells enable personalized modeling of P450 oxidoreductase deficiency	Matveeva, Anna; du Toit, Therina; Pandey, Amit V.	Symposia 15: Short Talks by PhD Students
Cryo-EM reveals an ensemble of CPR conformations in solution	Lepesheva, Galina	Symposia 12 P450 Regulation by interacting proteins
CYP450 mediated herb-drug interactions: exemplified by genetic polymorphism based inhibition on CYP450 by Radix Puerariae lobatae in healthy subjects	Zuo, Joan Z.	Symposia 1: P450 Pharmacology
CYP46A1 as a Pharmacologic Target for Alzheimer’s Disease and Other Brain Disorders	Pikuleva, Irina	Symposia 7 P450 Drug Design and targeting
Cytochrome P450 7B1 structure and analysis of mutations causing disease	Scott, Emily	Symposia 2 Structure of P450 and non-heme Oxygenases
Cytochrome P450 activity in sepsis: Insights into gene expression and enzymatic dysfunction	Halimi, Fellanza; Vandewalle, Jolien; Vanderhaeghen, Tineke; Cuypers, Charlotte; Alonso, Bruna; Cherlet, Marc; Garcia, Bruno; Herpain, Antoine; Timmermans, Steven; Libert, Claude; Schauvliege, Stijn; Croubels, Siska	Regulatory mechanisms of Cytochrome P450
Cytochrome P450 and steroidogenesis	Miller, Walter L.	Waterman Lecture by Prof. Walter L Miller
Cytochrome P450 classification through dynamic topological binding site description: Linking structure to function	Kuvek, Tea	Symposia 15: Short Talks by PhD Students
Cytochrome P450 CYP2D6 and heme oxygenase-1 exist as a complex that affects both CYP2D6 and HO-1 function	Backes, Wayne L.; Connick, J. Patrick; Stepter, Amari; Cawley, George; Eyer, Marilyn	Symposia 5 Protein Interactions
Cytochromes P450 as targets and biocatalysts for detoxification of steroid-mimicking endocrine disruptors.	Di Nardo, Giovanna; Giaretto, Francesco; Armellino, Francesca; Gazzano, Elena; Gilardi, Gianfranco	Symposia 10 P450 and Steroid Metabolism
Defining the worldwide diversity of cytochrome P450s	Nelson, David Ralph	Symposia 3: P450 Bioinformatics
Determining the role of an acidic residue in Cytochrome P450: Insights into the function of CYP2S1	Catalano, Jaclyn; Ahmed, Mostofa; Beaucejour, Chrisnaelle; Messina, Marisa	Symposia 16 Short Talks
Developing novel pro-insecticides to kill mosquito vectors of disease	Cooke, Brittany Hunter; Ching, Justin; Burns, Andrew R.; Knox, Jessica; Tan, Guihong; Samokhin, Philip; Durant, Andrew; Rabeda, Karolina; Martone, Vincent; Lycett, Gareth; Shi, Jin; Cummins, Carolyn; Paine, Mark; Andrews, Brenda; Boone, Charles; Lautens, Mark; Roy, Peter J.	Symposia 11 P450 Across Species
Direct Isolation and Reconstitution of Cytochrome Proteins in Polymer-Based Nanodiscs	Ramamoorthy, Ayyalusamy	Symposia 4: P450 Biophysics
Docking predictivity determinants for the P450 flexible active site	Suwała, Dominik; Hruška, Eugen	Symposia 4: P450 Biophysics continued
Drug metabolism and cytochrome P450 across species	Yamazaki, Hiroshi	Symposia 14Cytochrome P450 in Drug Metabolism
Drug Metabolism in the Pathobiome: The Impact of P. aeruginosa Cytochrome P450 Metabolism of Drugs and Endogenous Metabolites	Lampe, Jed Noah; Kandel, Sylvie Eliane	Symposia 14Cytochrome P450 in Drug Metabolism
Dual roles of the endogenous Ah receptor (AHR) ligand 6-Formylindolo[3,2-b]carbazole (FICZ) in the induction of pulmonary cytochrome P450 (CYP)1A1 induction by hyperoxia, and the attenuation of oxygen-mediated lung injury in mice In Vivo.	Moorthy, Dear. Bhagavatula; Chu, Dear. Chun; Wang, Dear. Lihua; Jiang, Dear. Weiwu	Symposia 1: P450 Pharmacology
Elucidating Biochemistry of Cytochrome P450 2U1 with respect to Lipid and Xenobiotic Metabolism	Tang, Yi Chien {Tiffany}; Das, Aditi	Symposia 4: P450 Biophysics continued
Emerging roles of extrahepatic cytochrome p450s in lipid and drug metabolism	Das, Aditi	Symposia 6 Catalytic Mechanisms of Cytochrome P450
Engineering efficient peroxygenase activity into cytochrome P450 Enzymes for selective C-H bond hydroxylations	Bell, Stephen	Symposia 2 Structure of P450 and non-heme Oxygenases
Enhancing the efficacy of NK cell therapy against glioblastoma by suppressing CYP17A1 activity	Hsu, Dear. Tsung-I	Symposia 8 Novel P450 Reactions and functions
Exploring novel P450 enzymes & redox partners from extremophilic regions by a metagenomic approach	Karagüler, Nevin Gül; Mumcu, Hande; Zaugg, Julian; Kayrav, Aycan; Dizer, Kaan; Nelson, David R.; Hughenholtz, Philip; Gillam, Elizabeth	Session 3 continued: P450 Bioinformatics
Fasting enhances diclofenac hepatotoxicity via the induction of multiple cytochrome p450 enzymes and glutathione depletion in mice	Lee, Yun-Hee	Symposia 16 Short Talks
First functional expression of a lichen cytochrome P450 enzymes enables in vitro usnic acid biosynthesis	Vu, Huynh Ngoc Dieu; Mittal, Navriti; Olafsdottir, Elin Soffia; Sorensen, John L.	Symposia 12 P450 Regulation by interacting proteins
Focusing the computational microscope on the dynamics of mammalian cytochrome P450s and their redox partners	Teuffel, Jonathan; Mukherjee, Goutam; Bosco Han, Sungho; Ber, Sophia; Elstner, Marcus; Wade, Rebecca	Symposia 4: P450 Biophysics continued
From lanosterol to desmosterol: Sterol-specific modulation of hepatic signalling and gene networks	Skubic, Cene; Kreft, Tinkara; Klun, Gregor Matej; Rozman, Damjana	Symposia 10 P450 and Steroid Metabolism Continued
Functional effects of protein-protein interactions in cytochrome P450 ensemble and their manifestation in the impact of alcohol on drug metabolism	Davydov, Dmitri R.	Symposia 5 Protein Interactions
Functional interactomics of cytochrome P450s	Gilep, Andrei; Svirid, Andrey; Kisel, Mariya; Yablokov, Evgeniy; Karputs, Elena; Tumilovich, Anastasia; Grabovec, Irina; Kaluzhskiy, Leonid; Ivanov, Alexey; Strushkevich, Natallia	Symposia 5 Protein Interactions
HLM chip: a microfluidic in vitro model for identifying mechanism-based cytochrome P450 inhibition	Rautsola, Iiro; Haapala, Markus; Paludetto, Marie-Noëlle; Niemi, Mikko; Backman, Janne; Sikanen, Tiina	Symposia 15: Short Talks by PhD Students
How important are mosquito P450s in the fight against malaria?	Paine, Mark	Symposia 11 P450 Across Species
Humanisation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) for modelling consequences of P450 induction in vivo	Macleod, A Kenneth; Kapelyukh, Yury; Read, Kevin D.; Wolf, C. Roland	Regulatory mechanisms of Cytochrome P450
Hydroxylation and epoxidation of terpenoid alcohols by engineered bacterial cytochrome P450	Jeong, Hae Chan; Kim, Jeong-Hoon; Seo, Yu Sun; Yun, Chul-Ho	Symposia 8 Novel P450 Reactions and functions
Hydroxylation and lyase reaction mechanisms in CYP17A1	Denisov, Ilia	Symposia 4: P450 Biophysics
Impact of Val334Ile and Val472Leu variants on cytochrome P450 oxidoreductase activity	Barata, Isabel S.; Lucato, Erica; Rojas Velazquez, Maria Natalia; Pandey, Amit V.	Symposia 12 P450 Regulation by interacting proteins
In vitro drug-drug interactions between oxycodone and commonly co-consumed drugs in rat and human liver microsomes	Gu, Weilong; Tyndale, Rachel F.	Symposia 16 Short Talks
Inducible Cyp51 knockout model revels sterol imbalance and hepatic alterations in adult mouse liver	Kreft, Tinkara; Blagotinšek Cokan, Kaja; Skubic, Cene; Perše, Martina; Wechtersbach, Karmen; Kojc, Nika; Jeruc, Jera; Debeljak, Željko; Mandić, Dario; Heffer, Marija; Matz-Soja, Madlen; Rozman, Damjana	Symposia 10 P450 and Steroid Metabolism Continued
Inhibition of cytochrome P450-dependent xenobiotic metabolism by NF-κB activation and subsequent JAK/STAT activation by the marine biotoxin okadaic acid	Braeuning, Dear. Albert	Symposia 1: P450 Pharmacology
Insights into the structural diversity of the cytochrome P450s	Smit, Martha Sophia	Symposia 3: P450 Bioinformatics
Integrating structural data to enhance CYP annotation in the P450Atlas	Śmieja, Piotr L.; Zadrożna, Marta; Gront, Dominik	Symposia 3: P450 Bioinformatics
Interaction of fatty acid binding protein 1 (FABP1) with cytochromes P450 3A4, 4A11, and 4F11	McCarty, Kevin D.; Guengerich, F. Peter	Symposia 15: Short Talks by PhD Students
Major factors influencing C–H bond hydroxylation reaction of branched alkanes by bacterial CYP102A1 enzymes	Cao, Ngoc Tan; Nguyen, Ngoc Anh; Lee, Yu-Jin; Jeong, Hae Chan; Yeom, Soo-Jin; Yun, Chul-Ho	Symposia 8 Novel P450 Reactions and functions
Mapping the metabolism of adrenal 11-oxy androgens in human primary hepatocytes	Smit, Suzanne E.; Keogh, Adrian; Stroka, Deborah; Albrecht, Christiane; Flück, Christa E.; du Toit, Therina	Symposia 10 P450 and Steroid Metabolism Continued
Maternal TCDD exposure causes growth retardation in rat fetus: Potential involvement of pregnancy-specific TCDD-dependent CYP3A1 induction	Ishii, Yuji	Symposia 12 P450 Regulation by interacting proteins
Mechanistic insights from new(ish) radical clock mechanistic probes	De Voss, James Joseph; Buczynski, Julia B.; Bell, Stephen G.; Williams, Craig M.; Giang, Peter D.; Churchman, Luke R.	Symposia 6 Catalytic Mechanisms of Cytochrome P450
New antifungals and new understanding of resistance in fungal pathogens.	Kelly, Steven	Symposia 14Cytochrome P450 in Drug Metabolism
New reactions and mechanisms of CYP152 peroxygenases	Li, Shengying	Symposia 8 Novel P450 Reactions and functions
Non-Steroidal Inhibitors of CYP17A1 for Prostate Cancer Therapy	Wróbel, Tomasz M.; Pandey, Amit V.; Jørgensen, Flemming S.; Björkling, Fredrik; Yakubu, Jibira; du Toit, Therina; Sharma, Katyayani; Harrington, Jeremiah C.; Grudzińska, Angelika; Rogova, Oksana; Rojas Velazquez, Maria N.	Symposia 7 P450 Drug Design and targeting
Novel vitamin D hydroxylation activity by the CYP3A4 variant I301T causing Type 3 rickets.	Yasuda, Kaori	Symposia 10 P450 and Steroid Metabolism Continued
P450 in green biotechnology and sustainable chemistry	Møller, Birger Lindberg	Plenary Lecture 4: Birger Lindberg Moller, P450 in Green Biotechnology and sustainable chemistry
P450 inhibition and carbon monoxide: possible pharmacological implications.	Gori, Muskan; Wang, Binghe	Symposia 8 Novel P450 Reactions and functions
P450 library screening for the oxyfunctionalization of N-heterocycles	Wassing, Alexander	Symposia 16 Short Talks
Pesticide toxification by human cytochrome P450s	Chen, Lucia; Flaget, Arthur; Knox, Jessica; Burns, Andrew; Farshour, Nazli H.; Cooke, Brittany; Ching, Justin; Jiang, Yulia; Al Qassar, Modhar; Lacoste, Jessica; Shuteriqi, Ermira; Usaj, Matej; Tan, Guihong; Costanzo, Michael; Kamal, Muntasir; Andrews, Brenda; Boone, Charles; Lautens, Mark; Roy, Peter	Symposia 11 P450 Across Species
PGE2-induced CYP1B1 activation might enhance neuronal excitation to promote glioblastoma progression and therapy resistance	Shen, Dear. Chih-Jie; Chang, Dear. Wen-Chang; Hsu, Dear. Tsung-I	Regulatory mechanisms of Cytochrome P450
Pharmacogenomics of cytochrome P450s: From drug response variability to cancer and beyond	Schwab, Matthias	Symposia 9 Genetics and Genomics of P450 and human diseases
Post-Translational Modifications of CYP4F11 by 4-Hydroxynonenal: ω-Hydroxylation Impairment and Potential Role in Immunosuppression	Skorokhod, Oleksii	Regulatory mechanisms of Cytochrome P450
Pregnane X receptor (PXR) antagonists in the regulation of cytochrome P450 genes	Pavek, Petr	Regulatory mechanisms of Cytochrome P450
Proliferation-Competent Primary-Like Hepatocytes as Platform to Investigate Drug-Drug Interactions and Hepatotoxicity	Anders, Lennard; Küpper, Jan-Heiner; Kammerer, Sarah	Symposia 16 Short Talks
Regulation of adrenal androgen production by thyroid hormones	Augsburger, Philipp; du Toit, Therina; Smit, Suzanne; Flück, Christa	Regulatory mechanisms of Cytochrome P450
Role of cytochromes P450 in the pathogenesis of Parkinson’s disease	Bernhardt, Rita	Symposia 9 Genetics and Genomics of P450 and human diseases
Selective chemical inhibition of CYP3A4 and CYP3A5	Chen, Taosheng	Symposia 7 P450 Drug Design and targeting
Sterol mediated stress response after diminished CYP51A1	Rozman, Damjana	Symposia 11 P450 Across Species
Structural and functional characterization of a novel P450 peroxygenase from the cyanobacterium Rivularia sp. MS3 (CYP152E8)	Correddu, Danilo; Catucci, Gianluca; Rosso, Samuele; Aleo, Valentina; Di Nardo, Giovanna; Gilardi, Gianfranco	Symposia 11 P450 Across Species
Structure and mechanism of plant 2-oxoglutarate-dependent dioxygenases catalyzing α-tomatine oxidation	Nagano, Shingo	Symposia 2 Structure of P450 and non-heme Oxygenases
Structure-function analysis and practical application of CYP105A1	Sakaki, Toshiyuki; Yoneda, Sachiyo; Takita, Teisuke; Mikami, Bunzo; Yasukawa, Kiyoshi; Hirano, Yu; Tamada, Taro; Yasuda, Kaori	Symposia 11 P450 Across Species
Tandem reactions of P450s and FMOs in xenobiotic metabolism	De Angelis, Melissa; Dong, Shiman; Tozzato, Chiara; Catucci, Gianluca; Gilardi, Gianfranco; Sadeghi, Sheila	Symposia 5 Protein Interactions
Targeting steroidogenic P450s with natural compounds and nanoparticles for cancer and endocrine disorders	Yakubu, Jibira; Natsaridis, Evangelos; B. Sousa, Isabel; Tagit, Oya; V. Pandey, Amit	Symposia 7 P450 Drug Design and targeting
Terminal hydroxylation of hydrocarbons by CYP153A36 from Acinetobacter radioresistens	Voicu, George Paul; Catucci, Gianluca; Correddu, Danilo; Opperman, Diederik Johannes; Gilardi, Gianfranco	Symposia 16 Short Talks
The CYP1A2 inhibition by a herbal formula Xin-yi-san: theophylline oxidation and risk assessment	Ueng, Yune-Fang	Symposia 1: P450 Pharmacology
The novel third-generation antipsychotic drug brexpiprazole modulate cytochrome P450 enzymes in the liver.	Danek, Przemysław Jan; Pukło, Renata; Daniel, Władysława Anna	Regulatory mechanisms of Cytochrome P450
The role of polygenic, structurally variable CYP2A6 on Smoking behaviours, Cessation, Brain Imaging and Disease.	Tyndale, Rachel	Symposia 9 Genetics and Genomics of P450 and human diseases
Toxicological and behavioral screening of zebrafish CYPs	Goldstone, Jared; Lamb, David; Alsop, Derek; Easwaramoorthy, Melissa; Wilson, Joanna; Stegeman, John	Symposia 11 P450 Across Species
Tracing evolutionary pathways of P450s using ancestral sequence reconstruction	Gillam, Elizabeth M. J.	Session 3 continued: P450 Bioinformatics
Traumatic brain injury alters the metabolic microenvironment and potentially impacts neuronal activity through the cholesterol metabolic enzyme Cyp46a1	Huang, Yi-Han; Yeh, Shiu-Hwa; Chuang, Jian-Ying	Symposia 10 P450 and Steroid Metabolism Continued
Two cytochrome P450 enzymes found in the resin acid-degrading bacterium Pseudomonas abieticivorans	Ortega, Facundo Andrés; Hasani, Merima; McKee, Lauren; Larsbrink, Johan	Session 3 continued: P450 Bioinformatics
Understanding CYP450-mediated drug bioactivation in the brain using mass spectrometry imaging.	Seneviratne, Herana Kamal	Symposia 14Cytochrome P450 in Drug Metabolism
Unraveling the molecular complexity of cytochrome P450 oxidoreductase: From enzyme mechanisms to liver disease	Kranendonk, Michel; Baptista, Catarina; Crispim, Daniel; Campelo, Diana; Esteves, Francisco	Symposia 12 P450 Regulation by interacting proteins
What happens after electron transfer to human cytochrome P450 17A1?	Auchus, Richard	Symposia 10 P450 and Steroid Metabolism
What NMR teaches us about P450 structure, dynamics and function.	Pochapsky, Thomas C.	Symposia 2 Structure of P450 and non-heme Oxygenases

24^th International Conference on Cytochrome P450

June 30, 2025 to July 4, 2025

Bern, Switzerland

Index of Titles