Conference Time: 16th June 2025, 10:44:48pm CEST
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P450 regulation by partners: Symposia 12 P450 Regulation by interacting proteins
Time:
Thursday, 03/July/2025:
2:00pm - 4:00pm
Session Chair: Dr. Galina Lepesheva , Vanderbilt University, United States of AmericaSession Chair: Dr. Yuji Ishii , Kyushu University, Japan
Location: Auditorium 004 199 Places
Session Topics:
12. Cytochrome P450 Regulation by interacting proteins
Presentations
2:00pm - 2:25pm Cryo-EM reveals an ensemble of CPR conformations in solution
Chair(s): Galina Lepesheva (Vanderbilt University School of Medicine)
2:25pm - 2:50pm Maternal TCDD exposure causes growth retardation in rat fetus: Potential involvement of pregnancy-specific TCDD-dependent CYP3A1 induction
Chair(s): Yuji Ishii (Kyushu University, Japan)
Presentations of the Symposium
Maternal TCDD exposure causes growth retardation in rat fetus: Potential involvement of pregnancy-specific TCDD-dependent CYP3A1 induction
Yuji Ishii 1 , Ryoto Hiyama1 , Fumiya Nakamoto1 , Chiho Ohta2 , Nobuyuki Koga2 , Yoshitaka Tanaka1 1 Kyushu University, Fukuoka, Japan, 2 Nakamura Gakuen University, Fukuoka, Japan
2:50pm - 3:20pm Unraveling the molecular complexity of cytochrome P450 oxidoreductase: From enzyme mechanisms to liver disease
Michel Kranendonk , Catarina Baptista, Daniel Crispim, Diana Campelo, Francisco Esteves
NOVA Medical School Universidade NOVA de Lisboa, Portugal
3:20pm - 3:35pm Impact of Val334Ile and Val472Leu variants on cytochrome P450 oxidoreductase activity
Isabel S. Barata , Erica Lucato, Maria Natalia Rojas Velazquez, Amit V. Pandey
3:35pm - 3:50pm First functional expression of a lichen cytochrome P450 enzymes enables in vitro usnic acid biosynthesis
Huynh Ngoc Dieu Vu , Navriti Mittal, Elin Soffia Olafsdottir, John L. Sorensen