Conference Agenda

Session
P450 Drug Design and targeting: Symposia 7 P450 Drug Design and targeting
Time:
Wednesday, 02/July/2025:
10:00am - 12:00pm

Session Chair: Dr. Irina Pikuleva, Case Western Reserve University, United States of America
Session Chair: Dr. Edward Thomas Morgan, Emory University, United States of America
 Location: Auditorium 003

199 Places
Session Topics:
7. Cytochrome P450 Drug Design and targeting

Presentations
10:00am - 10:30am

Non-Steroidal Inhibitors of CYP17A1 for Prostate Cancer Therapy

Tomasz M. Wróbel, Amit V. Pandey, Flemming S. Jørgensen, Fredrik Björkling, Jibira Yakubu, Therina du Toit, Katyayani Sharma, Jeremiah C. Harrington, Angelika Grudzińska, Oksana Rogova, Maria N. Rojas Velazquez


10:30am - 11:00am

CYP46A1 as a Pharmacologic Target for Alzheimer’s Disease and Other Brain Disorders

Chair(s): Irina Pikuleva (Case Western Reserve University, United States of America)

 

Presentations of the Symposium

 

CYP46A1 as a Pharmacologic Target for Alzheimer’s Disease and Other Brain Disorders

Irina Pikuleva
Case Western Reserve University, United States of America


11:00am - 11:15am

Targeting steroidogenic P450s with natural compounds and nanoparticles for cancer and endocrine disorders

Jibira Yakubu, Evangelos Natsaridis, Isabel B. Sousa, Oya Tagit, Amit V. Pandey


11:15am - 11:30am

Abiraterone-derived dual inhibitor targeting CYP17A1 and HDAC6 as a novel strategy to overcome temozolomide resistance in glioblastoma

Hong-Yi Lin, Tsung-I Hsu


11:30am - 12:00pm

Selective chemical inhibition of CYP3A4 and CYP3A5

Taosheng Chen