Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
P450 Drug Design and targeting: Symposia 7 P450 Drug Design and targeting
Time:
Wednesday, 02/July/2025:
10:00am - 12:00pm
Session Chair: Dr. Irina Pikuleva, Case Western Reserve University, United States of America Session Chair: Dr. Edward Thomas Morgan, Emory University, United States of America
Location:Auditorium 003
199 Places
Session Topics:
7. Cytochrome P450 Drug Design and targeting
Presentations
10:00am - 10:30am
Non-Steroidal Inhibitors of CYP17A1 for Prostate Cancer Therapy
Tomasz M. Wróbel, Amit V. Pandey, Flemming S. Jørgensen, Fredrik Björkling, Jibira Yakubu, Therina du Toit, Katyayani Sharma, Jeremiah C. Harrington, Angelika Grudzińska, Oksana Rogova, Maria N. Rojas Velazquez
10:30am - 11:00am
CYP46A1 as a Pharmacologic Target for Alzheimer’s Disease and Other Brain Disorders
Chair(s): Irina Pikuleva (Case Western Reserve University, United States of America)
Presentations of the Symposium
CYP46A1 as a Pharmacologic Target for Alzheimer’s Disease and Other Brain Disorders
Irina Pikuleva Case Western Reserve University, United States of America
11:00am - 11:15am
Targeting steroidogenic P450s with natural compounds and nanoparticles for cancer and endocrine disorders
Jibira Yakubu, Evangelos Natsaridis, Isabel B. Sousa, Oya Tagit, Amit V. Pandey
11:15am - 11:30am
Abiraterone-derived dual inhibitor targeting CYP17A1 and HDAC6 as a novel strategy to overcome temozolomide resistance in glioblastoma
Hong-Yi Lin, Tsung-I Hsu
11:30am - 12:00pm
Selective chemical inhibition of CYP3A4 and CYP3A5
