Conference Agenda
Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
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Session Overview |
| Date: Friday, 04/July/2025 | ||
| 9:00am - 10:00am |
Plenary Lecture 4: Plenary Lecture 4: Birger Lindberg Moller, P450 in Green Biotechnology and sustainable chemistry Location: Auditorium 003 Chair: Prof. Amit Pandey, University of Bern, Switzerland P450 in green biotechnology and sustainable chemistry |
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| 10:00am - 12:00pm |
P450 Regulation: Regulatory mechanisms of Cytochrome P450 Location: Auditorium 003 Chair: Prof. Petr Pavek, Charles University, Faculty of Pharmacy, Czech Republic Pregnane X receptor (PXR) antagonists in the regulation of cytochrome P450 genes 10:30am - 11:00am Humanisation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) for modelling consequences of P450 induction in vivo 11:00am - 11:15am Regulation of adrenal androgen production by thyroid hormones 11:15am - 11:30am Post-Translational Modifications of CYP4F11 by 4-Hydroxynonenal: ω-Hydroxylation Impairment and Potential Role in Immunosuppression The contribution has been accepted as poster PGE2-induced CYP1B1 activation might enhance neuronal excitation to promote glioblastoma progression and therapy resistance 11:30am - 11:45am The novel third-generation antipsychotic drug brexpiprazole modulate cytochrome P450 enzymes in the liver. 11:45am - 12:00pm Cytochrome P450 activity in sepsis: Insights into gene expression and enzymatic dysfunction |
P450 in Drug Metabolism: Symposia 14Cytochrome P450 in Drug Metabolism Location: Auditorium 004 Chair: Prof. Jed Noah Lampe, University of Colorado, United States of America Drug metabolism and cytochrome P450 across species 10:25am - 10:55am Drug Metabolism in the Pathobiome: The Impact of P. aeruginosa Cytochrome P450 Metabolism of Drugs and Endogenous Metabolites 10:55am - 11:25am New antifungals and new understanding of resistance in fungal pathogens. 11:25am - 11:55am Understanding CYP450-mediated drug bioactivation in the brain using mass spectrometry imaging. |
| 12:00pm - 1:00pm |
Lunch 4 July: Lunch 4 July Location: Poster Gallery |
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| 1:00pm - 2:30pm |
Short Talks by PhD Students: Symposia 15: Short Talks by PhD Students Location: Auditorium 003 Chair: Jibira Yakubu, University of Bern, Switzerland Chair: Anna Matveeva, University of Bern, Switzerland The contribution has been accepted as short oral presentation. Interaction of fatty acid binding protein 1 (FABP1) with cytochromes P450 3A4, 4A11, and 4F11 1:15pm - 1:30pm Complexation of cytochrome P450 17A1 with its redox proteins in a membrane: Insights from molecular dynamics simulation 1:30pm - 1:45pm Characterization of CYP1750B2 from C. tardaugens NBRC 16725 involved in estrogens degradation: possible applications in green wastewater treatment 1:45pm - 2:00pm The contribution has been accepted as short oral presentation. CRISPR/Cas9-generated POR knockout cells enable personalized modeling of P450 oxidoreductase deficiency 2:00pm - 2:15pm HLM chip: a microfluidic in vitro model for identifying mechanism-based cytochrome P450 inhibition 2:15pm - 2:30pm Cytochrome P450 classification through dynamic topological binding site description: Linking structure to function |
Short Talks: Symposia 16 Short Talks Location: Auditorium 004 Chair: Dr. Therina Du Toit, University Hospital Bern, Switzerland Chair: Prof. Giovanna Di Nardo, University of Torino, Italy Determining the role of an acidic residue in Cytochrome P450: Insights into the function of CYP2S1 1:15pm - 1:30pm Proliferation-Competent Primary-Like Hepatocytes as Platform to Investigate Drug-Drug Interactions and Hepatotoxicity 1:30pm - 1:45pm P450 library screening for the oxyfunctionalization of N-heterocycles 1:45pm - 2:00pm Terminal hydroxylation of hydrocarbons by CYP153A36 from Acinetobacter radioresistens 2:00pm - 2:15pm Fasting enhances diclofenac hepatotoxicity via the induction of multiple cytochrome p450 enzymes and glutathione depletion in mice 2:15pm - 2:30pm In vitro drug-drug interactions between oxycodone and commonly co-consumed drugs in rat and human liver microsomes |
| 2:30pm - 3:00pm |
Afternoon Tea: Afternoon Tea Location: Poster Gallery |
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| 3:00pm - 3:45pm |
Plenary 5: Plenary Lecture 5: Fred Guengerich P450, 2025: quo vadis? Location: Auditorium 003 Chair: Prof. Richard J. Auchus, University of Michigan, United States of America |
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| 3:45pm - 4:15pm |
Awards and Closing Ceremony: Awards and Closing Ceremony Location: Auditorium 003 Chair: Prof. Amit Pandey, University of Bern, Switzerland |
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